Results for:
PubChem ID: 460

2-methoxyphenol

Mass-Spectra

Compound Details

Synonymous names
orthomethoxyphenol
Hydroxyanisole
Methylcatachol
Methylcatechol
Methoxyphenol
Guaicolina
ortho-methoxyphenol
Pyrocatechol monomethyl ether
Beechwood creosote
Creosote
guaiacol
Guaiastil
Guajacol
Guajakol
LHGVFZTZFXWLCP-UHFFFAOYSA-N
Anastil
Catechol monomethyl ether
Creodon
Guaicol
Guajol
Guasol
guiacol
Methyl Catechol
o-Hydroxyanisole
o-Methoxyphenol
Pyrocatechol methyl ester
Pyroguaiac acid
methoxy phenol
ortho-Guaiacol
Wood creosote
2-Hydroxyanisole
Guaiacol, oxidation indicator
Nat.Guaiacol
2-Methoxyphenol
6-methoxyphenol
Creosote, beechwood
o-Guaiacol
o-Guiacol
a hydroxlyated aryl lignin fragment
Catechol mono methyl ether
JZ3
o--methoxyphenol
o-methoxy-Phenol
O-Methyl catechol
CREOSOTE, WOOD
6JKA7MAH9C
2-methoxy phenol
2-Methoxy-Phenol
2-methoxyphenol;
AC1L19AA
Guaiacol (natural)
UNII-6JKA7MAH9C
1-Hydroxy-2-methoxybenzene
AC1Q46B5
Creosote (wood)
Guajakol [Czech]
KSC204S1J
Phenol, methoxy-
2-(methyloxy)phenol
2-Methoxyphenol, Catechol monomethyl ether, Pyrocatechol monomethyl ether
2-Methoxyphenol; Catechol monomethyl ether; Pyrocatechol monomethyl ether
CHEMBL13766
Creosote [JAN]
Guaiacol (JAN)
Guaiacol [JAN]
NSC3815
SCHEMBL21626
3JYG22FD73
Creodon (TN)
CTK1A4914
Guaiacol (2-Methoxyphenol)
Guaiacol, European Pharmacopoeia (EP) Reference Standard
HMDB01398
M0121
Creosote (wood tar)
guaiacol (liquid) extra pure
Phenol, o-methoxy-
STR03604
1- hydroxy-2-methoxybenzene
bmse000436
bmse010027
C01502
C15572
CCRIS 2943
CCRIS 6004
D00117
Guaiacol [JAN:NF]
Guaiacol, pharmaceutical secondary standard; traceable to USP and PhEur
Guaiacol, United States Pharmacopeia (USP) Reference Standard
HMS2089D18
HMS2233P04
HMS3372N11
HSDB 1979
HSDB 4241
RCRA waste number U051
UNII-3JYG22FD73
AK114448
BT000121
CS-D1347
DNC009129
DTXSID0023113
LS-1906
NSC 3815
NSC-3815
NSC760376
OR025059
OR153692
OR163668
OR268520
OR343147
PHENOXY, 2-METHOXY-
PS-3252
SBB058681
STL281868
WLN: QR BO1
A843426
Beechwood creosote (Fagus spp.)
CHEBI:28591
DSSTox_CID_3113
Phenol, 2-methoxy-
AB1001888
AJ-63992
AN-17339
ANW-13634
DSSTox_GSID_23113
DSSTox_GSID_24853
EBD2205193
KB-30331
SC-18105
ST2410094
ACMC-209784
BDBM50240369
DSSTox_RID_76880
DSSTox_RID_77552
MFCD00002185
ZINC13512224
AI3-05615
CCG-214035
DB-024854
NSC-760376
RTR-028311
ST50214385
TR-028311
AKOS000118831
ghl.PD_Mitscher_leg0.900
I01-6054
Q-100002
FEMA No. 2532
FT-0626815
Guaiacol, puriss., 99%
MLS001055375
SMR000059155
90-05-1
Guaiacol, natural, >=99%, FG
Tox21_111031
Tox21_201136
Tox21_202990
Tox21_400004
F2173-0425
CAS-90-05-1
8021-39-4
Guaiacol, SAJ first grade, >=98.0%
Guaiacol, Vetec(TM) reagent grade, 98%
MCULE-5627336368
NCGC00090827-01
NCGC00090827-02
NCGC00090827-03
NCGC00090827-04
NCGC00090827-05
NCGC00090827-06
NCGC00090827-07
NCGC00258688-01
NCGC00260535-01
AB00876226_07
AB00876226-06
EINECS 201-964-7
EINECS 232-419-1
26638-03-9
Pharmakon1600-01506165
2-Methoxyphenol, 98% 250g
CAS-8021-39-4
EC 201-964-7
SR-01000838056
7519-EP2292227A2
7519-EP2295426A1
7519-EP2295427A1
7519-EP2305636A1
7519-EP2305683A1
7519-EP2308857A1
7519-EP2308861A1
7519-EP2311821A1
7519-EP2311839A1
7519-EP2314584A1
7519-EP2314589A1
7519-EP2316470A2
7519-EP2316832A1
7519-EP2316833A1
7519-EP2316837A1
MolPort-000-871-969
196981-EP2269977A2
196981-EP2371803A1
196981-EP2377843A1
SR-01000838056-2
InChI=1/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H
Microorganism:

Yes

IUPAC name2-methoxyphenol
SMILESCOC1=CC=CC=C1O
InchiInChI=1S/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3
FormulaC7H8O2
PubChem ID460
Molweight124.139
LogP1.51
Atoms17
Bonds17
H-bond Acceptor2
H-bond Donor1
Chemical Classificationbenzenoids ethers alcohols

mVOC Specific Details

Volatilization
The Henry's Law constant for o-methoxyphenol is as 1.2X10-6 atm-cu m/mole(1). This Henry's Law constant indicates that o-methoxyphenol is expected to volatilize from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 34 days(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 251 days(SRC). o-Methoxyphenol's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). o-Methoxyphenol is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 0.103 mm Hg(3).
Literature: (1) Sagebiel JC et al; Chemosphere 25: 1763-68 (1992) (2) Lyman WJ et al; Handbook of Chemical Property Estimation Methods. Washington, DC: Amer Chem Soc pp. 15-1 to 15-29 (1990) (3) Verschueren K; Handbook of Environmental Data of Organic Chemicals. 2nd ed. New York, NY: Van Nostrand Reinhold Co., p. 435 (1983)
Soil Adsorption
A log Koc of 1.60 for o-methoxyphenol, corresponding to a Koc of 40(SRC), was experimentally determined in a Brookston clay loam soil(1). A log Koc of 1.56(2), corresponding to a Koc of 36(SRC) has also been reported. According to a classification scheme(3), these Koc values suggest that o-methoxyphenol is expected to have very high mobility in soil. The pKa of o-methoxyphenol is 9.98(4), indicating that this compound will exist primarily in the undissociated form in the environment(SRC). The adsorption of the phenol occurrs by hydrogen bonding to sites on soil surfaces; ortho-substitution generally results in decreased adsorption compared to para-substitution due to steric hindrance(1).
Literature: (1) Boyd SA; Soil Sci 134: 337-43 (1982) (2) Schuurmann G et al; Environ Sci Technol 40: 7005-11 (2006). Supporting information. Predicition of the sorption of organic compounds into soil organic matter from molecular structure. Available from, as of Dec 22, 2009: http//pub.acs.org (3) Swann RL et al; Res Rev 85: 17-28 (1983) (4) Pearce PJ, Simkins RJJ; Can J Chem 46: 241-8 (1968)
Vapor Pressure
PressureReference
0.103 mm Hg 25 deg CVerschueren, K. Handbook of Environmental Data of Organic Chemicals. 2nd ed. New York, NY: Van Nostrand Reinhold Co., 1983., p. 435
MS-Links
1D-NMR-Links

Microorganisms emitting the compound
KingdomSpeciesBiological FunctionOrigin/HabitatReference
FungiTuber Aestivumn/aT. melanosporum was from the cultivated truffle zones in the province and T. aestivum from the natural truffle zones in the same regionCullere et al., 2010
FungiTuber Melanosporumn/aT. melanosporum was from the cultivated truffle zones in the province and T. aestivum from the natural truffle zones in the same regionCullere et al., 2010
BacteriaPseudomonas Simiae AUnarhizosphere of a soybean field in the province of Rajasthan, IndiaVaishnav et al., 2016
Method
KingdomSpeciesGrowth MediumApplied MethodVerification
FungiTuber Aestivumn/aGas chromatography-olfactometry (GC-O)
FungiTuber Melanosporumn/aGas chromatography-olfactometry (GC-O)
BacteriaPseudomonas Simiae AUNutrient broth; King's B agarGC/MSNo