4-HYDROXYBENZOIC ACID

99-96-7

p-Hydroxybenzoic acid

4-Carboxyphenol

p-Salicylic acid

Benzoic acid, 4-hydroxy-

para-Hydroxybenzoic acid

Benzoic acid, p-hydroxy-

p-carboxyphenol

Paraben-acid

4-Hydroxybenzoesaeure

p-Oxybenzoesaure

Kyselina 4-hydroxybenzoova

p-Oxybenzoesaure [German]

4-Hydroxybenzoicacid

NSC 4961

PHBA

parahydroxybenzoic acid

Acido p-idrossibenzoico

4-hydroxy-benzoic acid

Hydroxybenzoic acid

HSDB 7233

Acido p-idrossibenzoico [Italian]

Kyselina 4-hydroxybenzoova [Czech]

EINECS 202-804-9

UNII-JG8Z55Y12H

CCRIS 8812

JG8Z55Y12H

DTXSID3026647

CHEBI:30763

HYDROXYBENZOIC ACID, PARA

p-hydroxy benzoic acid

AI3-01003

p-hydroxy-Benzoic acid

NSC-4961

Benzoic acid, 4-hydroxy

Hydroxybenzenecarboxylic acid

4-HBA

CHEMBL441343

DTXCID806647

FEMA NO. 3986

EC 202-804-9

MFCD00002547

3pcc

3pch

4-hydroxy-benzoate

4-hydroxy benzoic acid

Benzoic acid, p-hydroxy

WLN: QVR DQ

PHB

CAS-99-96-7

NSC4961

SALICYLIC ACID IMPURITY A (EP IMPURITY)

SALICYLIC ACID IMPURITY A [EP IMPURITY]

DB04242

NCGC00166040-01

ACETYLSALICYLIC ACID IMPURITY A (EP IMPURITY)

ACETYLSALICYLIC ACID IMPURITY A [EP IMPURITY]

PROPYL HYDROXYBENZOATE IMPURITY A (EP IMPURITY)

PROPYL HYDROXYBENZOATE IMPURITY A [EP IMPURITY]

METHYL PARAHYDROXYBENZOATE IMPURITY A (EP IMPURITY)

METHYL PARAHYDROXYBENZOATE IMPURITY A [EP IMPURITY]

C00156

p-Salicylate

AE-848/32195059

p-hydroxy-Benzoate

4-hydoxybenzoic acid

4-hyroxybenzoic acid

phenol derivative, 8

4-hydroxylbenzoic acid

4-Hydroxy-benzoesaeure

4-hydroxybenzoi c acid

PHLORETIN_met004

4-hydroxyl benzoic acid

4-Hydroxybenzoate, III

AVOBENZONE_met002

para-hydroxy benzoic acid

bmse000092

bmse000583

SCHEMBL4110

BIDD:ER0706

4-Hydroxybenzenecarboxylic acid

p-Hydroxybenzoic Acid, Reagent

BDBM26194

P-HYDROXYBENZOIC ACID [MI]

CS-D1180

HY-Y0264

STR01287

Tox21_202342

Tox21_303301

AC-008

BBL011981

s3754

STL138745

4-HYDROXYBENZOIC ACID [FHFI]

4-HYDROXYBENZOIC ACID [HSDB]

4-HYDROXYBENZOIC ACID [INCI]

4-Hydroxybenzoic acid, >=99%, FG

AKOS000119033

AM87513

CCG-266143

MCULE-1367764897

NCGC00166040-02

NCGC00257058-01

NCGC00259891-01

H0207

NS00005418

4-Hydroxybenzoic acid, ReagentPlus(R), 99%

EN300-21461

D86505

4-Hydroxybenzoic acid, ReagentPlus(R), >=99%

4-Hydroxybenzoic acid, puriss., >=99.0% (T)

A858402

Q229970

46DD083D-BFD3-4CE1-B2D9-6C6D5FEFD3D9

J-660066

W-100004

4-Hydroxybenzoic acid, Vetec(TM) reagent grade, 99%

2-3-4'-TRIHYDROXY-4-METHOXYBENZOPHENONE_met005

F2191-0237

Z104498098

2-3-DIHYDROXY-4-METHOXY-4'-ETHOXYBENZOPHENONE_met009

4-Hydroxybenzoic acid, certified reference material, TraceCERT(R)

4-Hydroxybenzoic acid, Pharmaceutical Secondary Standard; Certified Reference Material

InChI=1/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10

30729-36-3

The Henry's Law constant for 4-hydroxybenzoic acid is estimated as 7.2X10-12 atm-cu m/mole(SRC) derived from its extrapolated vapor pressure, 1.9X10-7 mm Hg(1), and water solubility, 5000 mg/L(2). This Henry's Law constant indicates that 4-hydroxybenzoic acid is expected to be essentially nonvolatile from water surfaces(3). 4-Hydroxybenzoic acid's estimated Henry's Law constant indicates that volatilization from moist soil surfaces is not expected to occur(SRC). In addition, 4-hydroxybenzoic acid's pKa value of 4.54(4) indicates that it will exist almost entirely as an anion at pH values of 5 to 9 and therefore volatilization from water and moist soil surfaces is not expected to be an important fate process(SRC). 4-Hydroxybenzoic acid is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(1).
Literature: (1) Jones AH; J Chem Eng Data 5:196-200 (1960) (2) Yalkowsky SH, He Y, eds; Handbook of aqueous solubility data. Boca Raton, FL: CRC Press p. 377 (2003) (3) Lyman WJ et al; Handbook of Chemical Property Estimation Methods. Washington, DC: Amer Chem Soc pp. 15-1 to 15-29 (1990) (4) Bykova LN et al; Zh Obshch Khim 40: 2295-300 (1970)

Koc values of 142, 20, and 14 were measured according to a modified version of OECD guideline 106 for 4-hydroxybenzoic acid in a podzol (pH=2.8, C organic=4.85%, sand:silt:clay=89.2:8.2:2.6%), alfisol (pH=6.7, C organic=1.25%, sand:silt:clay=69.7:14.4:15.9%), and a sediment (pH=7.1, C organic=1.58%, sand:silt:clay=5.5:58.8:35.7%), respectively(1). According to a classification scheme(2), these Koc values suggest that 4-hydroxybenzoic acid is expected to have high to very high mobility in soil. The pKa of 4-hydroxybenzoic acid is 4.54(3), indicating that this compound will primarily exist in anion form in the environment and anions generally do not adsorb more strongly to organic carbon and clay than their neutral counterparts(4).
Literature: (1) Vonoepen B et al; Chemosphere 22: 285-304 (1991) (2) Swann RL et al; Res Rev 85: 17-28 (1983) (3) Bykova LN et al; Zh Obshch Khim 40: 2295-300 (1970) (4) Doucette WJ; pp. 141-188 in Handbook of Property Estimation Methods for Chemicals. Boethling RS, Mackay D, eds. Boca Raton, FL: Lewis Publ (2000)