| NEUTROPENIA | 102 |
| ANAEMIA | 93 |
| FEBRILE NEUTROPENIA | 87 |
| THROMBOCYTOPENIA | 86 |
| PANCYTOPENIA | 81 |
| RHABDOMYOLYSIS | 79 |
| ALANINE AMINOTRANSFERASE INCREASED | 79 |
| ASPARTATE AMINOTRANSFERASE INCREASED | 74 |
| NAUSEA | 66 |
| PYREXIA | 64 |
| NEUTROPHIL COUNT DECREASED | 56 |
| Platelet count decreased | 54 |
| Acute kidney injury | 52 |
| White blood cell count decreased | 50 |
| VOMITING | 49 |
| LEUKOPENIA | 45 |
| FATIGUE | 41 |
| BLOOD CREATINE PHOSPHOKINASE INCREASED | 39 |
| SEPSIS | 37 |
| HEPATIC FUNCTION ABNORMAL | 35 |
| ASTHENIA | 35 |
| Pneumonia | 33 |
| Off label use | 32 |
| Death | 30 |
| BLOOD ALKALINE PHOSPHATASE INCREASED | 30 |
| DIARRHOEA | 28 |
| TRANSAMINASES INCREASED | 27 |
| HEPATOTOXICITY | 25 |
| GAMMA-GLUTAMYLTRANSFERASE INCREASED | 25 |
| Dyspnoea | 24 |
| Blood bilirubin increased | 24 |
| DECREASED APPETITE | 23 |
| ABDOMINAL PAIN | 23 |
| Renal failure | 22 |
| BONE MARROW FAILURE | 22 |
| Device related infection | 20 |
| CARDIAC FAILURE | 20 |
| Malaise | 19 |
| EXTRAVASATION | 19 |
| Myalgia | 16 |
| HYPOALBUMINAEMIA | 16 |
| Haemoglobin decreased | 16 |
| HAEMATOTOXICITY | 16 |
| CONSTIPATION | 15 |
| URINARY TRACT INFECTION | 14 |
| Septic shock | 14 |
| Renal impairment | 14 |
| Pneumonitis | 14 |
| Hypokalaemia | 14 |
| ATRIAL FIBRILLATION | 14 |
| Underdose | 13 |
| RESPIRATORY FAILURE | 13 |
| INTERSTITIAL LUNG DISEASE | 13 |
| Infusion site extravasation | 13 |
| BLOOD CREATININE INCREASED | 13 |
| Pleural effusion | 12 |
| Hepatocellular injury | 12 |
| Ejection fraction decreased | 12 |
| Stomatitis | 11 |
| PULMONARY EMBOLISM | 11 |
| Oedema peripheral | 11 |
| Multiple organ dysfunction syndrome | 11 |
| Infection | 11 |
| HEPATIC ENZYME INCREASED | 11 |
| Blood albumin decreased | 11 |
| Drug dose omission | 10 |
| DEHYDRATION | 10 |
| CARDIAC ARREST | 10 |
| Ascites | 10 |
| Product use issue | 9 |
| NEUTROPENIC SEPSIS | 9 |
| Mucosal inflammation | 9 |
| Hepatic failure | 9 |
| Capillary leak syndrome | 9 |
| Liver disorder | 8 |
| Intestinal obstruction | 8 |
| HYPOTENSION | 8 |
| Hyponatraemia | 8 |
| Hypertransaminasaemia | 8 |
| Cough | 8 |
| Catheter site related reaction | 8 |
| CARDIAC FAILURE CONGESTIVE | 8 |
| Acute myeloid leukaemia | 8 |
| Wrong technique in product usage process | 7 |
| Pulmonary oedema | 7 |
| Product use in unapproved indication | 7 |
| Pain | 7 |
| Myelosuppression | 7 |
| Hypertension | 7 |
| General physical health deterioration | 7 |
| Febrile bone marrow aplasia | 7 |
| Disease progression | 7 |
| Device malfunction | 7 |
| APLASIA | 7 |
| Adverse event | 7 |
| Toxicity to various agents | 6 |
| RASH | 6 |
| Myocardial infarction | 6 |
| HYPERKALAEMIA | 6 |
| Hepatitis | 6 |
| Hepatic cytolysis | 6 |
| Cholestasis | 6 |
| Cellulitis | 6 |
| Catheter site erythema | 6 |
| Acute pulmonary oedema | 6 |
| Subileus | 5 |
| RENAL FAILURE ACUTE | 5 |
| Palmar-plantar erythrodysaesthesia syndrome | 5 |
| Oedema | 5 |
| Muscular weakness | 5 |
| Lung infection | 5 |
| Liver injury | 5 |
| Liver function test increased | 5 |
| Liver function test abnormal | 5 |
| Leiomyosarcoma | 5 |
| GASTROINTESTINAL HAEMORRHAGE | 5 |
| Erythema | 5 |
| Drug-induced liver injury | 5 |
| DRUG INTERACTION | 5 |
| Disseminated intravascular coagulation | 5 |
| Cardiomyopathy | 5 |
| ACUTE RESPIRATORY DISTRESS SYNDROME | 5 |
| Abdominal pain upper | 5 |
| Weight increased | 4 |
| Weight decreased | 4 |
| Tumour lysis syndrome | 4 |
| Troponin increased | 4 |
| Renal tubular necrosis | 4 |
| Product preparation error | 4 |
| Pneumocystis jirovecii pneumonia | 4 |
| NEUROPATHY PERIPHERAL | 4 |
| Myocarditis | 4 |
| Myelodysplastic syndrome | 4 |
| Lymphocyte count decreased | 4 |
| Lung disorder | 4 |
| Ileus | 4 |
| HYPOXIA | 4 |
| Hyperuricaemia | 4 |
| Electrocardiogram QT prolonged | 4 |
| Device infusion issue | 4 |
| Deep vein thrombosis | 4 |
| Chest pain | 4 |
| Catheter site pain | 4 |
| Bone marrow toxicity | 4 |
| Bacteraemia | 4 |
| ACUTE MYOCARDIAL INFARCTION | 4 |
| Venous thrombosis | 3 |
| Vascular device infection | 3 |
| Uterine leiomyosarcoma | 3 |
| Syncope | 3 |
| Supraventricular tachycardia | 3 |
| Somnolence | 3 |
| Soft tissue sarcoma | 3 |
| Shock | 3 |
| Product quality issue | 3 |
| Oesophagitis | 3 |
| Medical device site fibrosis | 3 |
| Liposarcoma | 3 |
| Insomnia | 3 |
| Infusion site necrosis | 3 |
| Incorrect dose administered | 3 |
| Inappropriate schedule of product administration | 3 |
| Hypophosphataemia | 3 |
| Hypocalcaemia | 3 |
| Hyperbilirubinaemia | 3 |
| Hospitalisation | 3 |
| Headache | 3 |
| Escherichia infection | 3 |
| Enteritis | 3 |
| Device related thrombosis | 3 |
| Device occlusion | 3 |
| Cytopenia | 3 |
| Complication associated with device | 3 |
| Cholecystitis acute | 3 |
| Catheter site inflammation | 3 |
| Cardiac disorder | 3 |
| CARBOHYDRATE ANTIGEN 125 INCREASED | 3 |
| Blood sodium decreased | 3 |
| Azotaemia | 3 |
| Arrhythmia | 3 |
| Administration site extravasation | 3 |
| Abdominal discomfort | 3 |
| Vertigo | 2 |
| URINARY RETENTION | 2 |
| Tumour haemorrhage | 2 |
| Thrombosis in device | 2 |
| Thrombosis | 2 |
| Synovial sarcoma metastatic | 2 |
| Swelling | 2 |
| Suicide attempt | 2 |
| Small intestinal obstruction | 2 |
| Skin necrosis | 2 |
| Seizure | 2 |
| Respiratory disorder | 2 |
| Renal disorder | 2 |
| Red blood cell count decreased | 2 |
| Rectal haemorrhage | 2 |
| Pruritus | 2 |
| Product substitution issue | 2 |
| Product dose omission | 2 |
| Pneumothorax | 2 |
| Pneumonia legionella | 2 |
| Pneumonia aspiration | 2 |
| Pharyngitis | 2 |
| Pericardial effusion | 2 |
| Paraesthesia | 2 |
| Pancreatitis | 2 |
| OVARIAN CANCER METASTATIC | 2 |
| Oliguria | 2 |
| Neuromuscular toxicity | 2 |
| Nervous system disorder | 2 |
| Neoplasm progression | 2 |
| Mood altered | 2 |
| Mixed liver injury | 2 |
| Medication error | 2 |
| Lymphopenia | 2 |
| Lipase increased | 2 |
| Left ventricular dysfunction | 2 |
| Jugular vein thrombosis | 2 |
| Injection site erythema | 2 |
| Infusion site reaction | 2 |
| Infusion related reaction | 2 |
| INFLUENZA LIKE ILLNESS | 2 |
| Influenza | 2 |
| Incorrect drug administration rate | 2 |
| Incorrect drug administration duration | 2 |
| Implant site ulcer | 2 |
| Implant site extravasation | 2 |
| Ileus paralytic | 2 |
| Hypomagnesaemia | 2 |
| Hypersensitivity | 2 |
| Hyperpyrexia | 2 |
| HYPERGLYCAEMIA | 2 |
| Herpes zoster | 2 |
| Hepatobiliary disease | 2 |
| Hepatitis acute | 2 |
| Hepatic enzyme abnormal | 2 |
| Hepatic cirrhosis | 2 |
| Heart rate increased | 2 |
| Haemorrhage | 2 |
| Haemoptysis | 2 |
| Haematuria | 2 |
| Generalised oedema | 2 |
| Gastrointestinal toxicity | 2 |
| Face oedema | 2 |
| Escherichia sepsis | 2 |
| Epistaxis | 2 |
| Embolism | 2 |
| Dyspepsia | 2 |
| Dry skin | 2 |
| Drug delivery system malfunction | 2 |
| Device leakage | 2 |
| Device issue | 2 |
| Delirium | 2 |
| Congestive cardiomyopathy | 2 |
| Confusional state | 2 |
| Colitis ischaemic | 2 |
| Clostridium difficile infection | 2 |
| CHEST DISCOMFORT | 2 |
| Cerebrovascular accident | 2 |
| Cardiovascular disorder | 2 |
| Cardiotoxicity | 2 |
| Cardiogenic shock | 2 |
| Cardiac failure acute | 2 |
| Blood potassium increased | 2 |
| Blood creatinine abnormal | 2 |
| BLOOD BILIRUBIN ABNORMAL | 2 |
| BLOOD ALKALINE PHOSPHATASE ABNORMAL | 2 |
| Back pain | 2 |
| Atrial flutter | 2 |
| ANXIETY | 2 |
| Angiosarcoma metastatic | 2 |
| Altered state of consciousness | 2 |
| ALANINE AMINOTRANSFERASE ABNORMAL | 2 |
| Acute respiratory failure | 2 |
| Acute leukaemia | 2 |
| Acute coronary syndrome | 2 |
| Wrong technique in device usage process | 1 |
| Wound infection staphylococcal | 1 |
| White blood cell count increased | 1 |
| White blood cell count | 1 |
| Visual impairment | 1 |
| Visual acuity reduced | 1 |
| Ventricular tachycardia | 1 |
| Ventricular hypokinesia | 1 |
| Venous thrombosis limb | 1 |
| Vasculitis | 1 |
| Urosepsis | 1 |
| Urogenital disorder | 1 |
| Urine output decreased | 1 |
| Urinary tract obstruction | 1 |
| Urinary tract disorder | 1 |
| Urinary sediment abnormal | 1 |
| Upper respiratory tract infection | 1 |
| Upper gastrointestinal haemorrhage | 1 |
| Unresponsive to stimuli | 1 |
| Tumour compression | 1 |
| Tremor | 1 |
| Treatment failure | 1 |
| Traumatic liver injury | 1 |
| Transient ischaemic attack | 1 |
| Toxic skin eruption | 1 |
| Torsade de pointes | 1 |
| Tissue injury | 1 |
| Thrombophlebitis migrans | 1 |
| Thrombophlebitis | 1 |
| Throat tightness | 1 |
| Thermal burn | 1 |
| Therapy interrupted | 1 |
| Therapy change | 1 |
| Therapeutic response decreased | 1 |
| Tachypnoea | 1 |
| Tachycardia | 1 |
| SYNCOPE VASOVAGAL | 1 |
| Swelling face | 1 |
| Supraventricular extrasystoles | 1 |
| Superior vena cava syndrome | 1 |
| Sudden death | 1 |
| Stress cardiomyopathy | 1 |
| Streptococcus test positive | 1 |
| Streptococcal bacteraemia | 1 |
| Staphylococcal sepsis | 1 |
| Staphylococcal osteomyelitis | 1 |
| Sputum increased | 1 |
| Spinal compression fracture | 1 |
| Small intestinal haemorrhage | 1 |
| Sleep disorder | 1 |
| Skin ulcer | 1 |
| Skin lesion | 1 |
| Skin exfoliation | 1 |
| Skin disorder | 1 |
| Sinus tachycardia | 1 |
| Sinus node dysfunction | 1 |
| Sinus disorder | 1 |
| Sinus bradycardia | 1 |
| Sinus arrest | 1 |
| SHOCK HAEMORRHAGIC | 1 |
| Second primary malignancy | 1 |
| Scoliosis | 1 |
| SCIATICA | 1 |
| Scar | 1 |
| Sarcoma | 1 |
| Retinopathy | 1 |
| Retinal detachment | 1 |
| Retching | 1 |
| Respiratory tract infection viral | 1 |
| Respiratory tract infection | 1 |
| Respiratory distress | 1 |
| Renal injury | 1 |
| Rash maculo-papular | 1 |
| Rash generalised | 1 |
| Radiation oesophagitis | 1 |
| Pyelonephritis | 1 |
| Putamen haemorrhage | 1 |
| Pulmonary mass | 1 |
| Pulmonary hypertension | 1 |
| Pulmonary haemorrhage | 1 |
| Pulmonary congestion | 1 |
| Psoriasis | 1 |
| Pseudomonal sepsis | 1 |
| Pseudoaldosteronism | 1 |
| PROTHROMBIN TIME PROLONGED | 1 |
| Protein total decreased | 1 |
| Prostate infection | 1 |
| Product quality control issue | 1 |
| Product packaging issue | 1 |
| Product label issue | 1 |
| Procalcitonin increased | 1 |
| Presyncope | 1 |
| Post procedural haemorrhage | 1 |
| Polyneuropathy | 1 |
| Pneumocystis jirovecii infection | 1 |
| Pleural thickening | 1 |
| PHLEBITIS | 1 |
| Phaeochromocytoma | 1 |
| Persistent depressive disorder | 1 |
| Peroneal nerve palsy | 1 |
| Peripheral sensory neuropathy | 1 |
| PERIPHERAL ISCHAEMIA | 1 |
| Pancreatitis acute | 1 |
| PALPITATIONS | 1 |
| Overdose | 1 |
| Ovarian cancer recurrent | 1 |
| OVARIAN CANCER | 1 |
| Otitis media | 1 |
| ORAL PAIN | 1 |
| Oral candidiasis | 1 |
| Oesophageal infection | 1 |
| Occupational exposure to product | 1 |
| Non-cardiac chest pain | 1 |
| Nodal arrhythmia | 1 |
| Neutrophilic dermatosis | 1 |
| Neurotoxicity | 1 |
| Nephropathy toxic | 1 |
| Needle issue | 1 |
| Necrotising fasciitis | 1 |
| Necrosis | 1 |
| Nasal herpes | 1 |
| Myocardial necrosis marker increased | 1 |
| Musculoskeletal pain | 1 |
| Musculoskeletal disorder | 1 |
| Muscle spasms | 1 |
| Muscle fatigue | 1 |
| Multi-organ failure | 1 |
| Mucous membrane disorder | 1 |
| Metastases to lung | 1 |
| Metastases to liver | 1 |
| Metabolic disorder | 1 |
| Metabolic acidosis | 1 |
| Medical device site thrombosis | 1 |
| Mass | 1 |
| Malignant neoplasm progression | 1 |
| Macrocytosis | 1 |
| Lymphatic disorder | 1 |
| Lymphangiosis carcinomatosa | 1 |
| Lymphangioleiomyomatosis | 1 |
| Lung opacity | 1 |
| Lower respiratory tract infection | 1 |
| Lower gastrointestinal haemorrhage | 1 |
| Loss of consciousness | 1 |
| Liver abscess | 1 |
| Liquid product physical issue | 1 |
| Leukocytosis | 1 |
| Leiomyosarcoma metastatic | 1 |
| Large intestine perforation | 1 |
| Large intestinal haemorrhage | 1 |
| Laboratory test abnormal | 1 |
| Kidney infection | 1 |
| Jaundice | 1 |
| Ischaemic stroke | 1 |
| Intestinal pseudo-obstruction | 1 |
| Intestinal perforation | 1 |
| Intestinal haemorrhage | 1 |
| Intercepted medication error | 1 |
| Intentional product use issue | 1 |
| Injection site thrombosis | 1 |
| Injection site swelling | 1 |
| Injection site paraesthesia | 1 |
| Injection site pain | 1 |
| Injection site necrosis | 1 |
| Injection site mass | 1 |
| Injection site extravasation | 1 |
| Infusion site pain | 1 |
| Infusion site irritation | 1 |
| Infusion site infection | 1 |
| Infusion site haemorrhage | 1 |
| Infusion site erythema | 1 |
| Infertility | 1 |
| Infected neoplasm | 1 |
| Infected lymphocele | 1 |
| Incorrect product storage | 1 |
| Implant site thrombosis | 1 |
| Implant site necrosis | 1 |
| Implant site inflammation | 1 |
| Implant site infection | 1 |
| Implant site erythema | 1 |
| Impaired gastric emptying | 1 |
| Hypothyroidism | 1 |
| Hypoproteinaemia | 1 |
| Hyperventilation | 1 |
| Hyperthyroidism | 1 |
| Hypertensive crisis | 1 |
| Hyperphosphatasaemia | 1 |
| Hypernatraemia | 1 |
| Hyperhidrosis | 1 |
| Hypercreatinaemia | 1 |
| Hypercalcaemia | 1 |
| HYDROTHORAX | 1 |
| Hydronephrosis | 1 |
| Hot flush | 1 |
| Hirsutism | 1 |
| Hip fracture | 1 |
| Herpes ophthalmic | 1 |
| Hepatorenal failure | 1 |
| HEPATITIS TOXIC | 1 |
| Hepatitis cholestatic | 1 |
| Hepatic lesion | 1 |
| Hepatic infection | 1 |
| Haemorrhoids | 1 |
| Haemorrhage intracranial | 1 |
| Haemoglobinaemia | 1 |
| Haematemesis | 1 |
| Gingivitis | 1 |
| Gingival pain | 1 |
| General physical condition abnormal | 1 |
| Gastrooesophageal reflux disease | 1 |
| Gastrointestinal perforation | 1 |
| Gastrointestinal pain | 1 |
| Gastrointestinal obstruction | 1 |
| Gastrointestinal necrosis | 1 |
| Gastrointestinal disorder | 1 |
| Gastroenteritis | 1 |
| Gastritis | 1 |
| Gastric haemorrhage | 1 |
| Gamma-glutamyltransferase | 1 |
| Furuncle | 1 |
| Fungaemia | 1 |
| Full blood count decreased | 1 |
| Fracture | 1 |
| Food intolerance | 1 |
| Folliculitis | 1 |
| Flushing | 1 |
| Fluid retention | 1 |
| Flatulence | 1 |
| Fistula of small intestine | 1 |
| Femoral neck fracture | 1 |
| Feeling hot | 1 |
| Fall | 1 |
| Failure to thrive | 1 |
| Facial paresis | 1 |
| Fabry's disease | 1 |
| Eye disorder | 1 |
| Extra-osseous Ewing's sarcoma | 1 |
| Expired product administered | 1 |
| Erythema multiforme | 1 |
| Enterobacter bacteraemia | 1 |
| Endocrine disorder | 1 |
| Encephalopathy | 1 |
| Embolism arterial | 1 |
| Embolic stroke | 1 |
| ELECTROMECHANICAL DISSOCIATION | 1 |
| ELECTROCARDIOGRAM CHANGE | 1 |
| Ejection fraction | 1 |
| Dyspnoea exertional | 1 |
| Dysphonia | 1 |
| Dysphagia | 1 |
| Dysgeusia | 1 |
| Dysarthria | 1 |
| Duodenal ulcer haemorrhage | 1 |
| Duodenal ulcer | 1 |
| DRUG TOXICITY | 1 |
| Drug intolerance | 1 |
| Drug ineffective | 1 |
| Drug hypersensitivity | 1 |
| Drug effect decreased | 1 |
| Drug administration error | 1 |
| Drug administered to patient of inappropriate age | 1 |
| DRUG ADMINISTERED AT INAPPROPRIATE SITE | 1 |
| Dizziness | 1 |
| Dilated cardiomyopathy | 1 |
| Dialysis | 1 |
| Diabetes mellitus | 1 |
| Device use issue | 1 |
| Device dislocation | 1 |
| Device breakage | 1 |
| Dermatitis bullous | 1 |
| Dermatitis | 1 |
| Depression | 1 |
| Depressed mood | 1 |
| Cytokine release syndrome | 1 |
| Cranial nerve paralysis | 1 |
| Contraindication to medical treatment | 1 |
| Condition aggravated | 1 |
| Colour blindness | 1 |
| Colon cancer | 1 |
| Colon adenoma | 1 |
| COLITIS | 1 |
| COGNITIVE DISORDER | 1 |
| Coagulopathy | 1 |
| Clostridium difficile colitis | 1 |
| Clostridial sepsis | 1 |
| Circulatory collapse | 1 |
| Chronic kidney disease | 1 |
| Cholecystitis | 1 |
| Cholangitis | 1 |
| Chills | 1 |
| Childhood | 1 |
| Cerebral infarction | 1 |
| Catheter site swelling | 1 |
| Catheter site pruritus | 1 |
| Catheter site discharge | 1 |
| Catheter site cellulitis | 1 |
| Carotid artery perforation | 1 |
| Cardiovascular insufficiency | 1 |
| Cardiopulmonary failure | 1 |
| Cardiac pacemaker insertion | 1 |
| Capillary permeability increased | 1 |
| Cancer fatigue | 1 |
| Calculus ureteric | 1 |
| Cachexia | 1 |
| Burning sensation | 1 |
| Bronchostenosis | 1 |
| Bradycardia | 1 |
| Body temperature increased | 1 |
| Blood uric acid increased | 1 |
| Blood thyroid stimulating hormone increased | 1 |
| Blood thyroid stimulating hormone decreased | 1 |
| Blood product transfusion dependent | 1 |
| Blood pressure systolic increased | 1 |
| Blood pressure increased | 1 |
| Blood lactate dehydrogenase increased | 1 |
| Blood glucose increased | 1 |
| Blood electrolytes decreased | 1 |
| Blood disorder | 1 |
| Blood creatine phosphokinase MB increased | 1 |
| Blood creatine phosphokinase | 1 |
| Blood creatine abnormal | 1 |
| Blood calcium decreased | 1 |
| Blood alkaline phosphatase | 1 |
| Blood albumin increased | 1 |
| Blood acid phosphatase increased | 1 |
| Blister | 1 |
| Bile duct stenosis | 1 |
| Bicytopenia | 1 |
| Auditory disorder | 1 |
| Aspartate aminotransferase abnormal | 1 |
| Aspartate aminotransferase | 1 |
| Arthralgia | 1 |
| Arteritis | 1 |
| ARTERIAL THROMBOSIS LIMB | 1 |
| Application site induration | 1 |
| Aplastic anaemia | 1 |
| Angiosarcoma | 1 |
| Angiopathy | 1 |
| Angina pectoris | 1 |
| Anal incontinence | 1 |
| Anaemia of malignant disease | 1 |
| Amylase increased | 1 |
| Alveolar rhabdomyosarcoma | 1 |
| Alopecia | 1 |
| Alanine aminotransferase | 1 |
| Akinaesthesia | 1 |
| Agitation | 1 |
| Adverse drug reaction | 1 |
| Adolescence | 1 |
| Administration site inflammation | 1 |
| Acute hepatic failure | 1 |
| Acinetobacter infection | 1 |
| Accidental overdose | 1 |
| Accidental exposure to product | 1 |
| Accident at home | 1 |
| Abdominal pain lower | 1 |
| Abdominal mass | 1 |
| Abdominal infection | 1 |
