Thiethylperazine


DB00372



General information:


Withdrawn ID: DB00372
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es): R06AD03
Molecular Formula: C22H29N3S2
Molweight: 399.616



Withdrawal information:


Withdrawn due to drug safety reasons:No
First approved: 1961
First withdrawn: 2009
Last withdrawn: 2009



Side-effects:

Total reported cases (submitted by medical professionals) with Thiethylperazine as primary suspect: 25


Reported final outcomes:
Hospitalization (initial or prolonged): 11
Life-Threatening condition: 4
Death: 0


Reported side-effects:

Side-effect Case number
DYSTONIA7
TORTICOLLIS5
EXTRAPYRAMIDAL DISORDER3
TREMOR3
DYSKINESIA3
LOSS OF CONSCIOUSNESS2
HYPONATRAEMIA2
TACHYCARDIA2
MUSCLE RIGIDITY2
HALLUCINATION, VISUAL1
EYE ROLLING1
GAIT DISTURBANCE1
GRAND MAL CONVULSION1
HAEMOLYTIC ANAEMIA1
JAW DISORDER1
HEADACHE1
INCONTINENCE1
Increased bronchial secretion1
APRAXIA1
EPILEPSY1
Electrocardiogram QT prolonged1
DYSPRAXIA1
DYSPNOEA1
DYSPHONIA1
DYSARTHRIA1
DRUG INTERACTION1
DEPRESSION1
CARDIO-RESPIRATORY ARREST1
BRADYKINESIA1
BENIGN PROSTATIC HYPERPLASIA1
URINARY RETENTION1
Pulmonary oedema1
Unresponsive to stimuli1
Toxicity to various agents1
TONIC CLONIC MOVEMENTS1
TONGUE SPASM1
TONGUE OEDEMA1
TARDIVE DYSKINESIA1
Tachypnoea1
Suicide attempt1
SPEECH DISORDER1
SOMNOLENCE1
SINGLE PHOTON EMISSION COMPUTERISED TOMOGRAM ABNORMAL1
SCOTOMA1
LARYNGEAL OEDEMA1
Psychomotor hyperactivity1
Personality disorder1
PARKINSONISM1
PAIN1
Overdose1
OCULOGYRIC CRISIS1
MULTIPLE MYELOMA1
MOVEMENT DISORDER1
MIGRAINE1
MASKED FACIES1
LIP OEDEMA1
LARYNGOSPASM1





Toxicity information:

Toxicity class: 4
Toxicity type: N/A
LD50: 680 mg/kg



External links:

ChEBML: CHEMBL1378
DrugBank: DB00372