Tacrine
General information:
| Withdrawn ID: | DB00382 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | N06DA01 |
| Molecular Formula: | C13H14N2 |
| Molweight: | 198.264 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | No |
|---|---|
| First approved: | 1993 |
| First withdrawn: | 2013 |
| Last withdrawn: | 2013 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| P05067 | 12.21 | Amyloid-beta precursor protein | A4_HUMAN |
| P06276 | 7 | Cholinesterase | CHLE_HUMAN |
| P22303 | 7.53 | Acetylcholinesterase | ACES_HUMAN |
| Q04844 | 152.28 | Acetylcholine receptor subunit epsilon | ACHE_HUMAN |
Toxicity information:
| Toxicity class: | 3 |
|---|---|
| Toxicity type: | N/A |
| LD50: | 290 mg/kg |
External links:
| ChEBML: | CHEMBL95 |
|---|---|
| DrugBank: | DB00382 |