Sulfinpyrazone
General information:
| Withdrawn ID: | 238 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | M04AB02 |
| Molecular Formula: | C23H20N2O3S |
| Molweight: | 404.482 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | No |
|---|---|
| First approved: | 1959 |
| First withdrawn: | 2009 |
| Last withdrawn: | 2009 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| B2RXH2 | 10000 | Lysine-specific demethylase 4E | KDM4E_HUMAN |
| P00352 | 794.3 | Retinal dehydrogenase 1 | AL1A1_HUMAN |
| P15428 | 10000 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | PGDH_HUMAN |
| Q6XQN6 | 0.5 | Nicotinate phosphoribosyltransferase | PNCB_HUMAN |
| Q99714 | 5011.9 | 3-hydroxyacyl-CoA dehydrogenase type-2 | HCD2_HUMAN |
| Q9NUW8 | 1122 | Tyrosyl-DNA phosphodiesterase 1 | TYDP1_HUMAN |
Toxicity information:
| Toxicity class: | 3 |
|---|---|
| Toxicity type: | N/A |
| LD50: | 298 mg/kg |
External links:
| ChEBML: | CHEMBL832 |
|---|---|
| DrugBank: | DB01138 |