Withdrawn ID: | w34 |
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Canonical SMILES: | |
Standard InChI: | |
Standard InChIKey: | |
ATC class(es): | J01MA09 |
Molecular Formula: | C19H22F2N4O3 |
Molweight: | 392.4 |
Withdrawn due to drug safety reasons: | Yes |
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First approved: | 1996 |
First withdrawn: | 2001 |
Last withdrawn: | 2001 |
Reference: | https://www.ncbi.nlm.nih.gov/pubmed/1971092 |
Target UniProtKB ID | Activity in nm | Target Name | Target gene |
---|---|---|---|
P28482 | 4466.8 | Mitogen-activated protein kinase 1 | MK01_HUMAN |
Toxicity class: | 4 |
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Toxicity type: | cardiovascular |
LD50: | 2000 mg/kg |
ChEBML: | CHEMBL850 |
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DrugBank: | DB01208 |