Sitaxentan
General information:
| Withdrawn ID: | w104 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | C02KX03 |
| Molecular Formula: | C18H15ClN2O6S2 |
| Molweight: | 454.905 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First approved: | 2006 |
| First death: | 2002 |
| First withdrawn: | 2010 |
| Last withdrawn: | 2010 |
| Reference: | https://www.ncbi.nlm.nih.gov/pubmed/22890981 |
Side-effects:
| Total reported cases (submitted by medical professionals) with Sitaxentan as primary suspect: | 8 |
|---|
Reported final outcomes:
| Death: | 3 |
|---|---|
| Hospitalization (initial or prolonged): | 2 |
Reported side-effects:
| Side-effect | Case number |
|---|---|
| CARDIAC FAILURE | 2 |
| HEPATIC FUNCTION ABNORMAL | 2 |
| LIVER FUNCTION TEST ABNORMAL | 2 |
| ANAEMIA | 1 |
| BLOOD CREATININE INCREASED | 1 |
| CARDIAC ARREST | 1 |
| CARDIO-RESPIRATORY ARREST | 1 |
| OEDEMA PERIPHERAL | 1 |
| PANCREATITIS | 1 |
| PULMONARY ARTERIAL HYPERTENSION | 1 |
| RENAL FAILURE ACUTE | 1 |
| RENAL IMPAIRMENT | 1 |
| RESPIRATORY ARREST | 1 |
Toxicity information:
| Toxicity type: | hepatic |
|---|
External links:
| ChEBML: | CHEMBL282724 |
|---|---|
| DrugBank: | DB06268 |