Procyclidine


168



General information:


Withdrawn ID: 168
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es): N04AA04
Molecular Formula: C19H29NO
Molweight: 287.44



Withdrawal information:


Withdrawn due to drug safety reasons:No
First approved: 1955



Side-effects:

Total reported cases (submitted by medical professionals) with Procyclidine as primary suspect: 23


Reported final outcomes:
Hospitalization (initial or prolonged): 9
Death: 6
Disability: 4
Congenital anomaly: 0


Reported side-effects:

Side-effect Case number
DRUG INTERACTION3
DYSTONIA3
MULTIPLE DRUG OVERDOSE3
HYPONATRAEMIA2
OVERDOSE2
CONFUSIONAL STATE2
PSYCHOTIC DISORDER2
CARDIO-RESPIRATORY ARREST2
BRAIN OEDEMA2
DYSKINESIA2
MUSCULOSKELETAL STIFFNESS2
SEDATION2
SOMNOLENCE2
AKATHISIA2
VOMITING2
DRUG EFFECT DECREASED1
Developmental hip dysplasia1
DIARRHOEA1
DILATATION VENTRICULAR1
CONSTIPATION1
HAEMOLYTIC ANAEMIA1
DISORIENTATION1
DIZZINESS1
Drooling1
FAECAL VOMITING1
HAEMOGLOBIN DECREASED1
GASTROINTESTINAL SOUNDS ABNORMAL1
Feeding disorder neonatal1
DRUG LEVEL INCREASED1
FAECALOMA1
ELECTROCARDIOGRAM QT PROLONGED1
BLOOD BILIRUBIN INCREASED1
ABDOMINAL DISTENSION1
ABDOMINAL PAIN1
ABDOMINAL RIGIDITY1
AGITATION1
Agitation neonatal1
AKINESIA1
AMNESIA1
ARRHYTHMIA1
ARTERITIS1
ASTHENIA1
BALANCE DISORDER1
DEPRESSED LEVEL OF CONSCIOUSNESS1
BRADYKINESIA1
CARDIOTOXICITY1
CATATONIA1
CHOREA1
COMA1
CONDITION AGGRAVATED1
LOSS OF CONSCIOUSNESS1
DEATH1
DEHYDRATION1
DELUSION1
RIGHT VENTRICULAR FAILURE1
PSYCHOMOTOR HYPERACTIVITY1
PULMONARY CONGESTION1
PULMONARY HAEMORRHAGE1
PULMONARY INFARCTION1
PULMONARY OEDEMA1
PYREXIA1
REFUSAL OF TREATMENT BY PATIENT1
RENAL IMPAIRMENT1
Respiratory distress1
RESTLESS LEGS SYNDROME1
RESTLESSNESS1
PSORIASIS1
ROAD TRAFFIC ACCIDENT1
SEPSIS1
SKIN DISORDER1
Somatic delusion1
SUICIDAL IDEATION1
THERAPEUTIC AGENT TOXICITY1
TREMOR1
UNEVALUABLE EVENT1
WATER INTOXICATION1
WEIGHT INCREASED1
NEUROTOXICITY1
INTESTINAL OBSTRUCTION1
LIP DISCOLOURATION1
WRONG DRUG ADMINISTERED1
LUNG DISORDER1
MITRAL VALVE DISEASE1
Movement disorder1
Muscle spasms1
Muscular weakness1
Myasthenia gravis1
MYOCARDITIS1
MYOCLONUS1
Insomnia1
OCULOGYRATION1
ORAL DISCHARGE1
ORTHOSTATIC HYPOTENSION1
PARKINSONISM1
PERICARDITIS1
Persecutory delusion1
PNEUMONIA ASPIRATION1
POLYDIPSIA1
POLYTRAUMATISM1
POOR PERSONAL HYGIENE1





Toxicity information:

Toxicity class: 4
Toxicity type: N/A
LD50: 395 mg/kg



External links:

ChEBML: CHEMBL86715
DrugBank: DB00387