Withdrawn ID: | w22 |
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Canonical SMILES: | |
Standard InChI: | |
Standard InChIKey: | |
ATC class(es): | R07AB53 |
Molecular Formula: | C6H10N4 |
Molweight: | 138.17 |
Withdrawn due to drug safety reasons: | Yes |
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First approved: | 1934 |
First withdrawn: | 1982 |
Last withdrawn: | 1982 |
Reference: | https://www.ncbi.nlm.nih.gov/pubmed/14322383 |
Target UniProtKB ID | Activity in nm | Target Name | Target gene |
---|---|---|---|
P10636 | 891.3 | Microtubule-associated protein tau | TAU_HUMAN |
P54132 | 2.8 | Bloom syndrome protein | BLM_HUMAN |
Toxicity class: | 3 |
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Toxicity type: | neurological |
LD50: | 88 mg/kg |
ChEBML: | CHEMBL116943 |
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DrugBank: |