Oxyphenbutazone
General information:
| Withdrawn ID: | w18 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | M01AA03 |
| S01BC02 | |
| Molecular Formula: | C19H20N2O3 |
| Molweight: | 324.374 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First approved: | 1960 |
| First death: | 1974 |
| First withdrawn: | 1984 |
| Last withdrawn: | 1992 |
| Reference: | https://www.ncbi.nlm.nih.gov/pubmed/5499222 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| P51151 | 6309.6 | Ras-related protein Rab-9A | RAB9A_HUMAN |
| Q6XQN6 | 0.3 | Nicotinate phosphoribosyltransferase | PNCB_HUMAN |
Toxicity information:
| Toxicity class: | 4 |
|---|---|
| Toxicity type: | hematological |
| LD50: | 329 mg/kg |
External links:
| ChEBML: | CHEMBL1228 |
|---|---|
| DrugBank: | DB03585 |