Noscapine

General information:

Withdrawn ID:	w5
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es):	R05DA07
Molecular Formula:	C22H23NO7
Molweight:	413.421

Withdrawal information:

Withdrawn due to drug safety reasons:	Yes
First approved:	1930
First withdrawn:	1991
Last withdrawn:	1991
Reference:	https://www.ncbi.nlm.nih.gov/pubmed/25980655

Side-effects:

Total reported cases (submitted by medical professionals) with Noscapine as primary suspect:	1

Reported final outcomes:

Hospitalization (initial or prolonged):	1

Reported side-effects:

Side-effect	Case number
THROMBOSIS	1
EMBOLISM	1
DRUG TOXICITY	1

Filtered ChEMBL targets:

Target UniProtKB ID	Activity in nm	Target Name	Target gene
O15244	2600	Solute carrier family 22 member 2	S22A2_HUMAN

Toxicity information:

Toxicity class:	4
Toxicity type:	carcinogenicity
LD50:	853 mg/kg

External links:

ChEBML:	CHEMBL364713
DrugBank: