Nomifensine
General information:
| Withdrawn ID: | w165 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | N06AX04 |
| Molecular Formula: | C16H18N2 |
| Molweight: | 238.327 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First approved: | 1977 |
| First death: | 1985 |
| First withdrawn: | 1986 |
| Last withdrawn: | 1986 |
| Reference: | https://www.ncbi.nlm.nih.gov/pubmed/12772401 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| P23975 | 3.8 | Sodium-dependent noradrenaline transporter | SC6A2_HUMAN |
| P31645 | 874 | Sodium-dependent serotonin transporter | SC6A4_HUMAN |
| Q01959 | 10 | Sodium-dependent dopamine transporter | SC6A3_HUMAN |
Toxicity information:
| Toxicity class: | 4 |
|---|---|
| Toxicity type: | hematological |
| LD50: | 1000 mg/kg |
External links:
| ChEBML: | CHEMBL273575 |
|---|---|
| DrugBank: | DB04821 |