Mesoridazine
General information:
| Withdrawn ID: | 1224 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | N05AC03 |
| Molecular Formula: | C21H26N2OS2 |
| Molweight: | 386.574 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | No |
|---|---|
| First approved: | 1970 |
| First withdrawn: | 2004 |
| Last withdrawn: | 2004 |
Side-effects:
| Total reported cases (submitted by medical professionals) with Mesoridazine as primary suspect: | 2 |
|---|
Reported final outcomes:
| Hospitalization (initial or prolonged): | 1 |
|---|
Reported side-effects:
| Side-effect | Case number |
|---|---|
| TORTICOLLIS | 1 |
| THOUGHT BLOCKING | 1 |
| SPERM COUNT ABNORMAL | 1 |
| SKIN ULCER | 1 |
| RASH PAPULAR | 1 |
| MYOCARDIAL INFARCTION | 1 |
| EXCESSIVE MASTURBATION | 1 |
| ERECTILE DYSFUNCTION | 1 |
| EAR DEFORMITY ACQUIRED | 1 |
| CHEST PAIN | 1 |
| BACK PAIN | 1 |
| AGGRESSION | 1 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| Q12809 | 316.23 | Potassium voltage-gated channel subfamily H member 2 | KCNH2_HUMAN |
Toxicity information:
| Toxicity class: | 4 |
|---|---|
| Toxicity type: | N/A |
| LD50: | 520 mg/kg |
External links:
| ChEBML: | CHEMBL1088 |
|---|---|
| DrugBank: | DB00933 |