Masoprocol

General information:

Withdrawn ID:	656
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es):	L01XX10
Molecular Formula:	C18H22O4
Molweight:	302.365

Withdrawal information:

Withdrawn due to drug safety reasons:	No
First approved:	1992
First withdrawn:	1996
Last withdrawn:	1996

Filtered ChEMBL targets:

Target UniProtKB ID	Activity in nm	Target Name	Target gene
O75496	7079.5	Geminin	GEMI_HUMAN
P00352	158.5	Retinal dehydrogenase 1	AL1A1_HUMAN
P02545	7943.3	Prelamin-A/C	LMNA_HUMAN
P06746	794.3	DNA polymerase beta	DPOLB_HUMAN
P15428	3162.3	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	PGDH_HUMAN
P16050	631	Polyunsaturated fatty acid lipoxygenase ALOX15	LOX15_HUMAN
P18054	2818.4	Polyunsaturated fatty acid lipoxygenase ALOX12	LOX12_HUMAN
P19838	7943.3	Nuclear factor NF-kappa-B p105 subunit	NFKB1_HUMAN
P40225	5011.9	Thrombopoietin	TPO_HUMAN
P46063	2511.9	ATP-dependent DNA helicase Q1	RECQ1_HUMAN
Q16665	7943.3	Hypoxia-inducible factor 1-alpha	HIF1A_HUMAN
Q99714	125.9	3-hydroxyacyl-CoA dehydrogenase type-2	HCD2_HUMAN

Toxicity information:

Toxicity class:	5
Toxicity type:	N/A
LD50:	2460 mg/kg

External links:

ChEBML:	CHEMBL313972
DrugBank:	DB00179