masitinib

General information:

Withdrawn ID:	EMA26
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es):	L01XE22
Molecular Formula:	C28H30N6OS
Molweight:	498.642

Withdrawal information:

Withdrawn due to drug safety reasons:	No

Filtered ChEMBL targets:

Target UniProtKB ID	Activity in nm	Target Name	Target gene
P00519	593	Tyrosine-protein kinase ABL1	ABL1_HUMAN
P09619	4743	Platelet-derived growth factor receptor beta	PGFRB_HUMAN
P11274	78	Breakpoint cluster region protein	BCR_HUMAN
P12236	6	ADP/ATP translocase 3	ADT3_HUMAN
P16083	469	Ribosyldihydronicotinamide dehydrogenase [quinone]	NQO2_HUMAN
P42684	354	Tyrosine-protein kinase ABL2	ABL2_HUMAN
P42685	643	Tyrosine-protein kinase FRK	FRK_HUMAN
Q08345	1119	Epithelial discoidin domain-containing receptor 1	DDR1_HUMAN
Q15067	14	Peroxisomal acyl-coenzyme A oxidase 1	ACOX1_HUMAN
Q16832	3956	Discoidin domain-containing receptor 2	DDR2_HUMAN

Toxicity information:

Toxicity type:	N/A

External links:

ChEBML:	CHEMBL1908391
DrugBank:	N/A