Lumiracoxib
General information:
| Withdrawn ID: | w76 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | M01AH06 |
| Molecular Formula: | C15H13ClFNO2 |
| Molweight: | 293.721 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First approved: | 2006 |
| First death: | 2007 |
| First withdrawn: | 2007 |
| Last withdrawn: | 2007 |
| Reference: | https://www.ncbi.nlm.nih.gov/pubmed/24099022 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| P35354 | 60 | Prostaglandin G/H synthase 2 | PGH2_HUMAN |
Toxicity information:
| Toxicity class: | 3 |
|---|---|
| Toxicity type: | hepatic |
| LD50: | 54.6 mg/kg |
External links:
| ChEBML: | CHEMBL404108 |
|---|---|
| DrugBank: | DB01283 |