Iophendylate


w250



General information:


Withdrawn ID: w250
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es): V08AD04
Molecular Formula: C19H29IO2
Molweight: 416.337



Withdrawal information:


Withdrawn due to drug safety reasons:Yes
First approved: 1946
First withdrawn: 1987
Last withdrawn: 1987
Reference: https://www.ncbi.nlm.nih.gov/pubmed/24769261



Side-effects:

Total reported cases (submitted by medical professionals) with Iophendylate as primary suspect: 3


Reported final outcomes:
Disability: 2
Hospitalization (initial or prolonged): 1


Reported side-effects:

Side-effect Case number
ARACHNOIDITIS2
Fall1
Diffuse idiopathic skeletal hyperostosis1
Drug prescribing error1
Dysaesthesia1
Dyspnoea1
Ear discomfort1
Encephalomalacia1
Erectile dysfunction1
Exostosis1
Eyelid injury1
Facet joint syndrome1
Deep vein thrombosis1
Fatigue1
Gait disturbance1
Headache1
Herpes zoster1
Hydrocephalus1
Hypoaesthesia1
Hypotension1
Hypotonia1
Influenza1
Bradycardia1
Anal incontinence1
Anxiety1
Aortic dilatation1
Arteriovenous fistula1
Asthenia1
Back pain1
Blood pressure diastolic decreased1
Blood pressure diastolic increased1
Blood pressure systolic increased1
Intervertebral disc degeneration1
Cellulitis1
Central cord syndrome1
Cervical cord compression1
Cervical radiculopathy1
Clonus1
Clumsiness1
Constipation1
CSF protein increased1
Cystitis1
Synovial cyst1
Pain in extremity1
Paraesthesia1
Paraplegia1
Peripheral swelling1
Peripheral venous disease1
Prostate cancer1
Pyrexia1
Quadriplegia1
Scoliosis1
Seizure1
Pain1
Syringomyelia1
Tethered cord syndrome1
Thrombocytopenia1
Thrombophlebitis1
Urethral stenosis1
Urinary incontinence1
Urinary retention1
Urinary tract infection1
Vertebral foraminal stenosis1
Musculoskeletal stiffness1
Intervertebral disc protrusion1
Joint space narrowing1
Left ventricular dysfunction1
Left ventricular hypertrophy1
Measles1
Meningeal disorder1
Meningism1
Mental impairment1
Muscular weakness1
White blood cell count increased1
Myalgia1
Myelopathy1
Nail hypertrophy1
Neck pain1
Neurogenic bladder1
Obesity1
Oedema peripheral1
Onycholysis1
Osteopenia1





Toxicity information:

Toxicity class: 5
Toxicity type: multiple
LD50: 2100 mg/kg



External links:

ChEBML: CHEMBL951
DrugBank: DB01187