Indoprofen
General information:
| Withdrawn ID: | w120 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | M01AE10 |
| Molecular Formula: | C17H15NO3 |
| Molweight: | 281.306 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First approved: | 1981 |
| First death: | 1982 |
| First withdrawn: | 1984 |
| Last withdrawn: | 1984 |
| Reference: | https://www.ncbi.nlm.nih.gov/pubmed/26071143 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| O15118 | 89.1 | NPC intracellular cholesterol transporter 1 | NPC1_HUMAN |
| P04637 | 10000 | Cellular tumor antigen p53 | P53_HUMAN |
| P10253 | 177.8 | Lysosomal alpha-glucosidase | LYAG_HUMAN |
| P42858 | 1995.3 | Huntingtin | HD_HUMAN |
| P51151 | 316.2 | Ras-related protein Rab-9A | RAB9A_HUMAN |
| Q16637 | 1258.9 | Survival motor neuron protein | SMN_HUMAN |
Toxicity information:
| Toxicity class: | 3 |
|---|---|
| Toxicity type: | carcinogenicity, gastrointestinal |
| LD50: | 60.83 mg/kg |
External links:
| ChEBML: | CHEMBL15870 |
|---|---|
| DrugBank: | DB08951 |