Guanethidine


1218



General information:


Withdrawn ID: 1218
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es): C02CC02
S01EX01
Molecular Formula: C10H22N4
Molweight: 198.309



Withdrawal information:


Withdrawn due to drug safety reasons:No
First approved: 1960



Side-effects:

Total reported cases (submitted by medical professionals) with Guanethidine as primary suspect: 1


Reported final outcomes:
Hospitalization (initial or prolonged): 1


Reported side-effects:

Side-effect Case number
HYPERTENSION1
ACCIDENTAL OVERDOSE1





Filtered ChEMBL targets:

Target UniProtKB ID Activity in nm Target Name Target gene
P02545 1412.5 Prelamin-A/C LMNA_HUMAN



Toxicity information:

Toxicity class: 3
Toxicity type: N/A
LD50: 280 mg/kg



External links:

ChEBML: CHEMBL765
DrugBank: DB01170