Fenoterol
General information:
| Withdrawn ID: | w85 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | G02CA03 |
| R03AC04 | |
| Molecular Formula: | C17H21NO4 |
| Molweight: | 303.353 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First approved: | 1971 |
| First death: | 1987 |
| First withdrawn: | 1990 |
| Last withdrawn: | 1990 |
| Reference: | https://www.ncbi.nlm.nih.gov/pubmed/7613161 |
Side-effects:
| Total reported cases (submitted by medical professionals) with Fenoterol as primary suspect: | 4 |
|---|
Reported final outcomes:
| Congenital anomaly: | 2 |
|---|
Reported side-effects:
| Side-effect | Case number |
|---|---|
| Tachycardia | 2 |
| Premature baby | 2 |
| Atrial septal defect | 2 |
| Vomiting | 1 |
| Systolic hypertension | 1 |
| Maternal drugs affecting foetus | 1 |
| Intentional overdose | 1 |
| Balance disorder | 1 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| P07550 | 100 | Beta-2 adrenergic receptor | ADRB2_HUMAN |
Toxicity information:
| Toxicity class: | 4 |
|---|---|
| Toxicity type: | cardiovascular |
| LD50: | 1600 mg/kg |
External links:
| ChEBML: | CHEMBL32800 |
|---|---|
| DrugBank: | DB01288 |