Withdrawn ID: | 235 |
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Canonical SMILES: | |
Standard InChI: | |
Standard InChIKey: | |
ATC class(es): | S01EC02 |
Molecular Formula: | C6H6Cl2N2O4S2 |
Molweight: | 305.159 |
Withdrawn due to drug safety reasons: | No |
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First approved: | 1958 |
First withdrawn: | 2007 |
Last withdrawn: | 2007 |
Target UniProtKB ID | Activity in nm | Target Name | Target gene |
---|---|---|---|
O43570 | 50 | Carbonic anhydrase 12 | CAH12_HUMAN |
P00915 | 25 | Carbonic anhydrase 1 | CAH1_HUMAN |
P00918 | 8 | Carbonic anhydrase 2 | CAH2_HUMAN |
P02545 | 354.8 | Prelamin-A/C | LMNA_HUMAN |
P22748 | 95 | Carbonic anhydrase 4 | CAH4_HUMAN |
P23280 | 79 | Carbonic anhydrase 6 | CAH6_HUMAN |
P35218 | 81 | Carbonic anhydrase 5A, mitochondrial | CAH5A_HUMAN |
P43166 | 6 | Carbonic anhydrase 7 | CAH7_HUMAN |
Q16790 | 34 | Carbonic anhydrase 9 | CAH9_HUMAN |
Q8N1Q1 | 23 | Carbonic anhydrase 13 | CAH13_HUMAN |
Q9ULX7 | 345 | Carbonic anhydrase 14 | CAH14_HUMAN |
Q9Y2D0 | 21 | Carbonic anhydrase 5B, mitochondrial | CAH5B_HUMAN |
Toxicity class: | 4 |
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Toxicity type: | N/A |
LD50: | 1710 mg/kg |
ChEBML: | CHEMBL17 |
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DrugBank: | DB07948 |