Colfosceril palmitate
General information:
| Withdrawn ID: | 1404 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | R07AA01 |
| Molecular Formula: | C40H80NO8P |
| Molweight: | 734.039 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | No |
|---|---|
| First approved: | 1990 |
Side-effects:
| Total reported cases (submitted by medical professionals) with Colfosceril palmitate as primary suspect: | 9 |
|---|
Reported final outcomes:
| Death: | 2 |
|---|---|
| Hospitalization (initial or prolonged): | 1 |
Reported side-effects:
| Side-effect | Case number |
|---|---|
| Medical device complication | 3 |
| Pneumothorax | 3 |
| Pulmonary interstitial emphysema syndrome | 2 |
| Pulmonary haemorrhage | 2 |
| Neonatal hypoxia | 1 |
| Respiratory failure | 1 |
| Renal failure | 1 |
| Reflux laryngitis | 1 |
| Pulmonary hypoplasia | 1 |
| Oxygen saturation decreased | 1 |
| No therapeutic response | 1 |
| Acute respiratory failure | 1 |
| MIGRAINE | 1 |
| Intraventricular haemorrhage neonatal | 1 |
| Hepatic failure | 1 |
| Haemorrhage intracranial | 1 |
| General physical health deterioration | 1 |
| Bradycardia neonatal | 1 |
| Blood pH decreased | 1 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| Q16637 | 1778.3 | Survival motor neuron protein | SMN_HUMAN |
Toxicity information:
| Toxicity class: | 4 |
|---|---|
| Toxicity type: | N/A |
| LD50: | 420 mg/kg |
External links:
| ChEBML: | CHEMBL1200737 |
|---|---|
| DrugBank: |