Cefoperazone


1027



General information:


Withdrawn ID: 1027
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es): J01DD12
J01DD62
Molecular Formula: C25H27N9O8S2
Molweight: 645.67



Withdrawal information:


Withdrawn due to drug safety reasons:No
First approved: 1982



Side-effects:

Total reported cases (submitted by medical professionals) with Cefoperazone as primary suspect: 38


Reported final outcomes:
Death: 12
Hospitalization (initial or prolonged): 9
Life-Threatening condition: 2


Reported side-effects:

Side-effect Case number
ANAPHYLACTIC SHOCK9
HYPERSENSITIVITY3
Erythema2
HYPOTENSION2
Chills2
Pyrexia2
RASH2
DYSPNOEA2
VOMITING2
ASTHMA2
SYNCOPE2
ANAPHYLACTIC REACTION2
NAUSEA2
Liver injury2
Dry skin1
Crystal urine1
Drug hypersensitivity1
Condition aggravated1
Drug reaction with eosinophilia and systemic symptoms1
Coagulation time prolonged1
EPIDERMOLYSIS BULLOSA1
Erythema multiforme1
EYE DISORDER1
EYELID OEDEMA1
Coma1
COLD SWEAT1
Coagulopathy1
Haematuria1
CHEST PAIN1
CHEST DISCOMFORT1
Cerebral infarction1
Cerebral haemorrhage neonatal1
CARDIO-RESPIRATORY ARREST1
CARDIAC ARREST1
Blood loss anaemia1
Atrial fibrillation1
Acute myocardial infarction1
Acute coronary syndrome1
ABDOMINAL PAIN UPPER1
Palpitations1
Ventricular fibrillation1
Tremor1
TOXIC EPIDERMAL NECROLYSIS1
Tachypnoea1
Stevens-Johnson syndrome1
SHOCK1
RETINAL DETACHMENT1
Restlessness1
RESPIRATORY ARREST1
Renal disorder1
Rash maculo-papular1
Pulse absent1
Pulmonary haemorrhage1
Puerperal infection1
Peritoneal haemorrhage1
FACE OEDEMA1
Ocular hyperaemia1
Monocyte percentage increased1
Lymphocyte percentage increased1
Kounis syndrome1
IRITIS1
Inflammation1
Hyperpyrexia1
HYPERHIDROSIS1
Hepatic haematoma1
HEADACHE1
Haemorrhage subcutaneous1
Gastrointestinal haemorrhage1
Gastric haemorrhage1
Flushing1





Toxicity information:

Toxicity class: 6
Toxicity type: N/A
LD50: 12000 mg/kg



External links:

ChEBML: CHEMBL507674
DrugBank: DB01329