Carmofur


w271



General information:


Withdrawn ID: w271
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es): L01BC04
Molecular Formula: C11H16FN3O3
Molweight: 257.261



Withdrawal information:


Withdrawn due to drug safety reasons:Yes
Reference: https://www.ncbi.nlm.nih.gov/pubmed/19029469



Filtered ChEMBL targets:

Target UniProtKB ID Activity in nm Target Name Target gene
P02545 100 Prelamin-A/C LMNA_HUMAN
Q13510 20.7 Acid ceramidase ASAH1_HUMAN
Q16637 199.5 Survival motor neuron protein SMN_HUMAN



Toxicity information:

Toxicity class: 3
Toxicity type: neurological
LD50: 268 mg/kg



External links:

ChEBML: CHEMBL460499
DrugBank: DB09010