Buprenorphine

General information:

Withdrawn ID:	w240
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es):	N02AE01
	N07BC01
	N07BC51
Molecular Formula:	C29H41NO4
Molweight:	467.64

Withdrawal information:

Withdrawn due to drug safety reasons:	Yes
First approved:	1978
First death:	1991
First withdrawn:	1991
Last withdrawn:	1991
Reference:	https://www.ncbi.nlm.nih.gov/pubmed/25024861

Side-effects:

Total reported cases (submitted by medical professionals) with Buprenorphine as primary suspect:	14110

Reported final outcomes:

Hospitalization (initial or prolonged):	3230
Death:	1449
Life-Threatening condition:	471
Disability:	170
Congenital anomaly:	128
Intervention required to prevent permanent impairment/damage:	46

Reported side-effects:

Side-effect	Case number
DRUG WITHDRAWAL SYNDROME	1923
DRUG DEPENDENCE	1890
Drug abuse	1193
PAIN	1143
NAUSEA	948
OVERDOSE	804
EMOTIONAL DISTRESS	765
DEATH	741
DRUG INEFFECTIVE	668
Foetal exposure during pregnancy	653
VOMITING	652
OFF LABEL USE	630
Maternal exposure during pregnancy	613
Product use issue	588
Toxicity to various agents	554
PRODUCT ADHESION ISSUE	523
HEADACHE	512
INJECTION SITE PAIN	508
Intentional product use issue	484
APPLICATION SITE PRURITUS	475
DRUG WITHDRAWAL SYNDROME NEONATAL	465
Wrong technique in product usage process	453
ANXIETY	408
Intentional product misuse	399
SOMNOLENCE	384
SUBSTANCE ABUSE	378
APPLICATION SITE ERYTHEMA	373
HYPERHIDROSIS	349
DRUG EXPOSURE DURING PREGNANCY	302
APPLICATION SITE RASH	281
Inappropriate schedule of product administration	267
DIZZINESS	258
INADEQUATE ANALGESIA	251
RASH	248
MALAISE	242
APPLICATION SITE PAIN	242
FEELING ABNORMAL	231
Exposure during pregnancy	225
WITHDRAWAL SYNDROME	224
FATIGUE	216
DYSPNOEA	213
INSOMNIA	210
DRUG EFFECT DECREASED	205
CONFUSIONAL STATE	203
APPLICATION SITE VESICLES	198
PRURITUS	196
ABORTION SPONTANEOUS	195
DEPRESSION	188
Intentional underdose	184
INTENTIONAL DRUG MISUSE	183
OEDEMA PERIPHERAL	179
PRODUCT SUBSTITUTION ISSUE	178
DIARRHOEA	173
Product preparation error	172
Injection site erythema	171
DRUG INTERACTION	171
COMA	168
AGITATION	168
PREMATURE BABY	164
CONSTIPATION	163
ALCOHOL ABUSE	163
HOSPITALISATION	162
TREMOR	160
Application site burn	156
SUICIDAL IDEATION	155
HALLUCINATION	155
LOSS OF CONSCIOUSNESS	154
MIOSIS	148
Drug screen negative	142
STOMATITIS	137
WEIGHT DECREASED	136
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION	136
FALL	133
RESPIRATORY DEPRESSION	132
EUPHORIC MOOD	132
DRUG SCREEN POSITIVE	132
Premature delivery	130
WRONG TECHNIQUE IN DRUG USAGE PROCESS	128
INCORRECT ROUTE OF DRUG ADMINISTRATION	128
HYPERSENSITIVITY	127
Decreased appetite	126
COMPLETED SUICIDE	125
URTICARIA	123
Asthenia	122
APPLICATION SITE IRRITATION	118
Injection site extravasation	117
PNEUMONIA	115
Drug use disorder	114
ACCIDENTAL OVERDOSE	114
PYREXIA	113
ADVERSE EVENT	110
HEPATITIS C	107
CONDITION AGGRAVATED	104
ENDOCARDITIS	101
TACHYCARDIA	98
DRUG HYPERSENSITIVITY	98
ABDOMINAL PAIN	97
UNEVALUABLE EVENT	96
PRODUCT SOLUBILITY ABNORMAL	96
CHEST PAIN	94
ABDOMINAL PAIN UPPER	94
MIGRAINE	93
SUICIDE ATTEMPT	92
Seizure	92
Exposure during breast feeding	92
DELIRIUM	92
PRODUCT QUALITY ISSUE	91
ROAD TRAFFIC ACCIDENT	88
CONVULSION	88
INCORRECT DOSE ADMINISTERED	87
THERAPY CESSATION	83
PAIN IN EXTREMITY	80
MUSCLE SPASMS	79
Drug detoxification	79
LETHARGY	78
DRUG INTOLERANCE	78
DEPRESSED LEVEL OF CONSCIOUSNESS	78
ASPHYXIA	77
IRRITABILITY	76
CHILLS	76
AGGRESSION	76
ABDOMINAL DISCOMFORT	76
HYPOTENSION	74
THERAPEUTIC RESPONSE DECREASED	73
SEDATION	73
Product packaging quantity issue	73
PRODUCT PHYSICAL ISSUE	72
INJECTION SITE INFECTION	72
INJECTION SITE ABSCESS	72
BACK PAIN	72
URINARY RETENTION	71
UNRESPONSIVE TO STIMULI	71
OEDEMA	71
Drug effect incomplete	71
RESTLESSNESS	69
HYPERTENSION	68
PULMONARY OEDEMA	67
Prescribed overdose	67
DISORIENTATION	67
RHABDOMYOLYSIS	66
Injection site pruritus	66
ERYTHEMA	66
ABORTION INDUCED	66
PALPITATIONS	65
Low birth weight baby	65
SWOLLEN TONGUE	64
SEPSIS	64
Oral mucosal blistering	64
DRUG DIVERSION	64
MENTAL DISORDER	63
Injection site swelling	63
PSYCHOTIC DISORDER	62
INTENTIONAL OVERDOSE	62
ARTHRALGIA	62
Accidental exposure to product by child	62
Oral administration complication	61
DYSARTHRIA	60
DENTAL CARIES	60
PULMONARY EMBOLISM	59
Drug prescribing error	58
APPLICATION SITE DISCOLOURATION	58
WEIGHT INCREASED	57
SWELLING	57
CARDIO-RESPIRATORY ARREST	57
MYALGIA	55
MATERNAL DRUGS AFFECTING FOETUS	55
BLISTER	55
Therapeutic product effect incomplete	54
NO ADVERSE EVENT	54
MYOCARDIAL INFARCTION	54
BLOOD PRESSURE INCREASED	54
PARAESTHESIA	53
MEMORY IMPAIRMENT	53
GAIT DISTURBANCE	53
DISTURBANCE IN ATTENTION	53
APPLICATION SITE SCAR	53
SYNCOPE	52
PNEUMONIA ASPIRATION	52
AMNESIA	52
Product dispensing error	51
DYSGEUSIA	51
APPLICATION SITE EXFOLIATION	51
Application site discharge	49
Peripheral swelling	48
APPLICATION SITE REACTION	48
STAPHYLOCOCCAL INFECTION	47
POISONING	47
Injection site bruising	47
Acute kidney injury	47
ABSCESS	47
THERAPEUTIC RESPONSE UNEXPECTED	46
INJECTION SITE ULCER	46
APPLICATION SITE EROSION	46
VISION BLURRED	45
SEPTIC SHOCK	45
PREMATURE LABOUR	45
GLOSSODYNIA	45
DRY MOUTH	45
CARDIAC FAILURE	45
Application site dryness	45
RESPIRATORY ARREST	44
RENAL FAILURE	44
OXYGEN SATURATION DECREASED	44
Incorrect route of product administration	44
DRUG EFFECT INCREASED	44
DEEP VEIN THROMBOSIS	44
ALTERED STATE OF CONSCIOUSNESS	44
RESPIRATORY DISTRESS	43
PERIPHERAL ISCHAEMIA	43
NERVOUSNESS	43
Application site urticaria	43
ADVERSE DRUG REACTION	43
ABNORMAL BEHAVIOUR	43
HEPATIC ENZYME INCREASED	42
DRUG ABUSER	42
Device leakage	42
CARDIAC ARREST	42
Tongue blistering	41
RHINORRHOEA	41
RESPIRATORY FAILURE	41
MOUTH ULCERATION	41
GENERAL PHYSICAL HEALTH DETERIORATION	41
BRAIN OEDEMA	41
TOOTH DISORDER	40
SLEEP DISORDER	40
ORAL DISCOMFORT	40
DRUG TOXICITY	40
Drug delivery system removal	40
BURNING SENSATION	40
APPLICATION SITE SWELLING	40
URINARY TRACT INFECTION	39
PLACENTAL DISORDER	39
INJECTION SITE NECROSIS	39
HEART RATE INCREASED	39
HALLUCINATION, VISUAL	39
Foetal growth restriction	39
Extra dose administered	39
COLD SWEAT	39
SKIN ULCER	38
RASH PRURITIC	38
HYPOAESTHESIA	38
DYSPHAGIA	38
Drug administered at inappropriate site	38
BRADYCARDIA	38
PRURITUS GENERALISED	37
INJURY	37
DEPENDENCE	37
DEHYDRATION	37
CARDIAC DISORDER	37
ASTHMA	37
VERTIGO	36
SEROTONIN SYNDROME	36
Product administered at inappropriate site	36
MYDRIASIS	36
Accidental exposure to product	36
PARANOIA	35
JAUNDICE	35
HYPOXIA	35
CEREBROVASCULAR ACCIDENT	35
JAUNDICE NEONATAL	34
INTENTIONAL MISUSE	34
Injection site cellulitis	34
Gastrooesophageal reflux disease	34
Dermatitis contact	34
ACCIDENTAL DRUG INTAKE BY CHILD	34
Therapeutic response shortened	33
Stress cardiomyopathy	33
PRODUCT DOSAGE FORM ISSUE	33
Product colour issue	33
PROCEDURAL PAIN	33
HOT FLUSH	33
Breakthrough pain	33
SWELLING FACE	32
RETCHING	32
PANCREATITIS	32
MEDICATION ERROR	32
Injection site warmth	32
INFECTION	32
COGNITIVE DISORDER	32
ANAPHYLACTIC REACTION	32
ANAEMIA	32
ACCIDENTAL EXPOSURE	32
SMALL FOR DATES BABY	31
MENTAL IMPAIRMENT	31
INTERVERTEBRAL DISCITIS	31
HYPOAESTHESIA ORAL	31
ERECTILE DYSFUNCTION	31
DYSKINESIA	31
DRUG INEFFECTIVE FOR UNAPPROVED INDICATION	31
DISCOMFORT	31
DEPRESSED MOOD	31
BRADYPNOEA	31
PSYCHOMOTOR HYPERACTIVITY	30
PREGNANCY	30
NEOPLASM MALIGNANT	30
Influenza like illness	30
IMPAIRED DRIVING ABILITY	30
DYSURIA	30
CYANOSIS	30
CHEST DISCOMFORT	30
CELLULITIS	30
Alopecia	30
Sleep apnoea syndrome	29
ORAL PAIN	29
ORAL DISORDER	29
NEONATAL RESPIRATORY DISTRESS SYNDROME	29
MUSCULAR WEAKNESS	29
Injection site irritation	29
HEPATIC FAILURE	29
ENDOCARDITIS STAPHYLOCOCCAL	29
BALANCE DISORDER	29
VISUAL IMPAIRMENT	28
Product physical consistency issue	28
PHARYNGEAL OEDEMA	28
FLUSHING	28
CRYING	28
SKIN NECROSIS	27
RASH GENERALISED	27
INJECTION SITE REACTION	27
Drug level decreased	27
Dermatitis allergic	27
ARRHYTHMIA	27
Application site haemorrhage	27
STILLBIRTH	26
SKIN IRRITATION	26
RASH MACULAR	26
NIGHTMARE	26
MYOCLONUS	26
HALLUCINATION, AUDITORY	26
GLOSSITIS	26
EPILEPSY	26
ANGER	26
PRODUCT TASTE ABNORMAL	25
Product dose omission	25
Product dispensing issue	25
Premature rupture of membranes	25
POISONING DELIBERATE	25
MENTAL STATUS CHANGES	25
Injection site vesicles	25
Injection site induration	25
HYPOGLYCAEMIA	25
ELECTROCARDIOGRAM QT PROLONGED	25
Stress	24
PRODUCT FORMULATION ISSUE	24
Pre-eclampsia	24
LACRIMATION INCREASED	24
JOINT SWELLING	24
Injection site inflammation	24
Hepatitis	24
FEELING HOT	24
CONTUSION	24
TOOTHACHE	23
Product prescribing error	23
Pneumothorax	23
Placental hypertrophy	23
Multiple organ dysfunction syndrome	23
LYMPHADENOPATHY	23
INCOHERENT	23
FAECALOMA	23
DEVELOPMENTAL DELAY	23
CAESAREAN SECTION	23
Substance use disorder	22
SPEECH DISORDER	22
Skin reaction	22
RESTLESS LEGS SYNDROME	22
PALLOR	22
NECK PAIN	22
LIBIDO DECREASED	22
GASTROINTESTINAL DISORDER	22
DISABILITY	22
BLOOD CREATINE PHOSPHOKINASE INCREASED	22
YAWNING	21
THROAT TIGHTNESS	21
MOOD ALTERED	21
Loss of personal independence in daily activities	21
Injection site erosion	21
FORMICATION	21
FEELING OF BODY TEMPERATURE CHANGE	21
DRUG DISPENSING ERROR	21
CHRONIC OBSTRUCTIVE PULMONARY DISEASE	21
CARDIAC FAILURE CONGESTIVE	21
BLOOD PRESSURE DECREASED	21
Application site scab	21
ACUTE RESPIRATORY DISTRESS SYNDROME	21
ACCIDENTAL POISONING	21
WHEEZING	20
TREATMENT NONCOMPLIANCE	20
Therapy change	20
SKIN BURNING SENSATION	20
PANCREATITIS ACUTE	20
NECROSIS	20
MOBILITY DECREASED	20
MANIA	20
Injection site rash	20
INJECTION SITE HAEMORRHAGE	20
FEELING COLD	20
ENCEPHALOPATHY	20
DELUSION	20
COMPARTMENT SYNDROME	20
ARTHRITIS BACTERIAL	20
APPLICATION SITE DERMATITIS	20
ABDOMINAL DISTENSION	20
Tongue discomfort	19
Therapy non-responder	19
SURGERY	19
SEPTIC EMBOLUS	19
Night sweats	19
LUNG DISORDER	19
LIP SWELLING	19
Incorrect product administration duration	19
DERMATITIS	19
ASPIRATION	19
APPLICATION SITE ULCER	19
AGITATION NEONATAL	19
TOOTH LOSS	18
TONGUE ULCERATION	18
SELECTIVE ABORTION	18
PRODUCT CONTAMINATION	18
Premature separation of placenta	18
PERSECUTORY DELUSION	18
Oropharyngeal pain	18
Learning disability	18
INTENTIONAL SELF-INJURY	18
HYPOTHERMIA	18
HYPOKALAEMIA	18
HEART RATE DECREASED	18
ERYSIPELAS	18
DYSPEPSIA	18
DERMO-HYPODERMITIS	18
C-REACTIVE PROTEIN INCREASED	18
BIPOLAR DISORDER	18
ARTHRITIS	18
ABSCESS LIMB	18
ABNORMAL DREAMS	18
WOUND	17
THROMBOCYTOPENIA	17
Therapeutic product effect decreased	17
SCHIZOPHRENIA	17
RESPIRATORY ACIDOSIS	17
Product use in unapproved indication	17
Pre-existing condition improved	17
PHOTOPHOBIA	17
PARAESTHESIA ORAL	17
NERVOUS SYSTEM DISORDER	17
MUSCLE TWITCHING	17
HAEMATEMESIS	17
Exposure via breast milk	17
Emotional disorder	17
DIABETES MELLITUS	17
APHASIA	17
TINNITUS	16
THERAPY NAIVE	16
SNEEZING	16
SKIN EXFOLIATION	16
RIB FRACTURE	16
RESPIRATORY RATE DECREASED	16
Renal impairment	16
PANIC ATTACK	16
INFLAMMATION	16
HEAD INJURY	16
FEEDING DISORDER NEONATAL	16
EMBOLIC STROKE	16
Drug effect less than expected	16
Drug dose omission	16
DEMENTIA	16
CARDIOMYOPATHY	16
APNOEA	16
ANGIOEDEMA	16
ACCIDENT	16
VAGINAL HAEMORRHAGE	15
TREATMENT FAILURE	15
PULMONARY CONGESTION	15
Product administration error	15
LIVER FUNCTION TEST ABNORMAL	15
Injection site discolouration	15
Injection site discharge	15
Hypersomnia	15
FLUID RETENTION	15
DYSPHONIA	15
COUGH	15
Cleft palate	15
CEREBRAL HAEMORRHAGE	15
CARDIAC VALVE VEGETATION	15
ARTHROPATHY	15
ANKLE FRACTURE	15
ULCER	14
THROMBOSIS	14
THROAT IRRITATION	14
SUBCUTANEOUS ABSCESS	14
STAPHYLOCOCCAL SEPSIS	14
SKIN LESION	14
SALIVARY HYPERSECRETION	14
RESPIRATORY DISORDER NEONATAL	14
RESPIRATORY DISORDER	14
PRODUCT ODOUR ABNORMAL	14
OSTEOMYELITIS	14
Neonatal disorder	14
NASOPHARYNGITIS	14
INTRA-UTERINE DEATH	14
HEPATIC CIRRHOSIS	14
Foetal non-stress test abnormal	14
FEAR	14
EJECTION FRACTION DECREASED	14
DRUG ADMINISTRATION ERROR	14
CONVULSION NEONATAL	14
BRADYCARDIA FOETAL	14
ATRIAL FIBRILLATION	14
APATHY	14
ALCOHOL WITHDRAWAL SYNDROME	14
VISCERAL CONGESTION	13
VASCULAR PSEUDOANEURYSM	13
TONGUE DISORDER	13
TALIPES	13
Substance dependence	13
RENAL TUBULAR NECROSIS	13
RENAL DISORDER	13
RASH ERYTHEMATOUS	13
POTENTIATING DRUG INTERACTION	13
Poor feeding infant	13
MUSCULOSKELETAL STIFFNESS	13
LUNG NEOPLASM MALIGNANT	13
LUNG ABSCESS	13
LOGORRHOEA	13
INFLUENZA	13
IMPAIRED WORK ABILITY	13
HYPOVENTILATION	13
HYPERVENTILATION	13
HYPERTHERMIA	13
GUN SHOT WOUND	13
GRAND MAL CONVULSION	13
Gestational diabetes	13
GASTROINTESTINAL HAEMORRHAGE	13
FOETAL DISTRESS SYNDROME	13
DYSPHORIA	13
DRUG-INDUCED LIVER INJURY	13
DIPLOPIA	13
CIRCULATORY COLLAPSE	13
CHOLESTASIS	13
CEREBRAL INFARCTION	13
Brachial artery entrapment syndrome	13
Application site inflammation	13
URINARY INCONTINENCE	12
UNDERDOSE	12
TREMOR NEONATAL	12
TRANSAMINASES INCREASED	12
Thermal burn	12
SKIN DISCOLOURATION	12
SINUS TACHYCARDIA	12
QUADRIPARESIS	12
Product storage error	12
PRESYNCOPE	12
Prescription form tampering	12
Prescription drug used without a prescription	12
Piloerection	12
Neuropathy peripheral	12
NEURALGIA	12
NEONATAL ASPIRATION	12
MUSCULOSKELETAL PAIN	12
Mouth swelling	12
MENINGITIS	12
Medication residue present	12
LIVER DISORDER	12
INTESTINAL OBSTRUCTION	12
HYPOPNOEA	12
HYPONATRAEMIA	12
HYPERTONIA	12
Housebound	12
HAEMORRHAGE	12
Generalised tonic-clonic seizure	12
FRACTURE	12
Foreign body embolism	12
Dry skin	12
DRUG LEVEL INCREASED	12
DEATH NEONATAL	12
Contraindicated product administered	12
CONGENITAL ANOMALY	12
CHOLELITHIASIS	12
ALANINE AMINOTRANSFERASE INCREASED	12
ACUTE RESPIRATORY FAILURE	12
ACUTE MYOCARDIAL INFARCTION	12
ACTIVITIES OF DAILY LIVING IMPAIRED	12
Venous thrombosis	11
Sudden infant death syndrome	11
STREPTOCOCCAL INFECTION	11
Sexual dysfunction	11
SCAR	11
RENAL INFARCT	11
Product packaging issue	11
Post-traumatic stress disorder	11
POLLAKIURIA	11
NEPHROPATHY	11
Myelopathy	11
METABOLIC ACIDOSIS	11
MALNUTRITION	11
LYMPHOEDEMA	11
Injection site discomfort	11
HYPOTONIA NEONATAL	11
Head discomfort	11
HALLUCINATIONS, MIXED	11
GLOMERULONEPHRITIS ACUTE	11
GENERALISED OEDEMA	11
Foetal death	11
Feeling jittery	11
EYE SWELLING	11
CHROMATURIA	11
Candida infection	11
Bone pain	11
BLOOD GLUCOSE INCREASED	11
Application site odour	11
Application site bruise	11
ALCOHOLISM	11
AFFECTIVE DISORDER	11
Wrong patient received product	10
WHITE BLOOD CELL COUNT INCREASED	10
Urinary hesitation	10
UPPER LIMB FRACTURE	10
Transcription medication error	10
Tissue injury	10
Sudden death	10
STAPHYLOCOCCAL BACTERAEMIA	10
SPLENIC INFARCTION	10
Sinusitis	10
RENAL FAILURE ACUTE	10
Product dose omission in error	10
POOR QUALITY SLEEP	10
PLEURAL EFFUSION	10
NEPHROLITHIASIS	10
MUSCLE TIGHTNESS	10
MOOD SWINGS	10
LYMPHANGITIS	10
LEUKOCYTOSIS	10
ISCHAEMIA	10
INJECTION SITE OEDEMA	10
Illness	10
HYPOGLYCAEMIA NEONATAL	10
Hypercapnia	10
Hyperaesthesia	10
Hepatic encephalopathy	10
FOOT FRACTURE	10
FOETAL MALFORMATION	10
FAECES DISCOLOURED	10
Exposure via body fluid	10
EXCORIATION	10
ESCHAR	10
Dysmorphism	10
CONGESTIVE CARDIOMYOPATHY	10
CARDIAC MURMUR	10
Brain injury	10
ASCITES	10
Application site papules	10
ACCIDENTAL DEATH	10
Victim of crime	9
TRICUSPID VALVE DISEASE	9
TOOTH FRACTURE	9
Tooth erosion	9
Tongue discolouration	9
TACHYPNOEA	9
SHOCK	9
Oral mucosal erythema	9
ORAL CANDIDIASIS	9
OLIGOHYDRAMNIOS	9
NECROTISING FASCIITIS	9
MUSCLE RIGIDITY	9
MOVEMENT DISORDER	9
Mouth haemorrhage	9
Ischaemic stroke	9
Injection site mass	9
Injection site hypersensitivity	9
Injection site haematoma	9
Incorrect drug administration duration	9
INCONTINENCE	9
HEPATOTOXICITY	9
Hepatic function abnormal	9
Hepatic cytolysis	9
HEART RATE IRREGULAR	9
ENDOPHTHALMITIS	9
DYSSTASIA	9
Disease recurrence	9
CRYOGLOBULINAEMIA	9
COVID-19	9
COMA SCALE ABNORMAL	9
Cluster headache	9
Behavioural addiction	9
Application site discomfort	9
Aphthous ulcer	9
Adrenal insufficiency	9
ACUTE HEPATIC FAILURE	9
ACNE	9
ACIDOSIS	9
VISUAL ACUITY REDUCED	8
VASCULITIS	8
TRICUSPID VALVE INCOMPETENCE	8
TRANSIENT ISCHAEMIC ATTACK	8
Tooth discolouration	8
Substance-induced psychotic disorder	8
STATUS EPILEPTICUS	8
Stasis dermatitis	8
Spinal operation	8
SKIN DISORDER	8
Renal tubular disorder	8
RASH PUSTULAR	8
PANCYTOPENIA	8
ORTHOSTATIC HYPOTENSION	8
MICROCEPHALY	8
MALABSORPTION	8
LOWER LIMB FRACTURE	8
LOCALISED INFECTION	8
LIMB INJURY	8
LEUKOPENIA	8
Intentional dose omission	8
HYPOXIC-ISCHAEMIC ENCEPHALOPATHY	8
HYPOTONIA	8
HYPERGLYCAEMIA	8
HEPATITIS ACUTE	8
HEPATIC CONGESTION	8
HAEMATOCHEZIA	8
GYNAECOMASTIA	8
FEMUR FRACTURE	8
FEMORAL NECK FRACTURE	8
EXTRAPYRAMIDAL DISORDER	8
Expulsion of medication	8
Drug tolerance	8
COORDINATION ABNORMAL	8
Contraindicated drug administered	8
COAGULOPATHY	8
Behaviour disorder	8
BACTERIAL INFECTION	8
Autism	8
ASPARTATE AMINOTRANSFERASE INCREASED	8
APPLICATION SITE HYPERSENSITIVITY	8
APPENDICITIS	8
ANGINA PECTORIS	8
ANEURYSM	8
Anaphylactic shock	8
ADVERSE REACTION	8
ABASIA	8
Weight decrease neonatal	7
URINE ANALYSIS ABNORMAL	7
Torsade de pointes	7
THROMBOPHLEBITIS	7
Thinking abnormal	7
Therapeutic product ineffective	7
Tension	7
SUBSTANCE USE	7
STRABISMUS	7
Spinal compression fracture	7
Sopor	7
Sluggishness	7
Sensitivity of teeth	7
Scratch	7
RHEUMATOID ARTHRITIS	7
Rash papular	7
Product use complaint	7
PNEUMONITIS	7
PLACENTA PRAEVIA	7
Photosensitivity reaction	7
PARALYSIS	7
OSTEONECROSIS	7
OSTEOARTHRITIS	7
Oral mucosal eruption	7
OBSTRUCTIVE AIRWAYS DISORDER	7
Neutropenia	7
NASAL SEPTUM DEVIATION	7
MYOCARDITIS	7
MUCOSAL INFLAMMATION	7
MITRAL VALVE INCOMPETENCE	7
LIVIDITY	7
Liver injury	7
LEUKOENCEPHALOPATHY	7
Intercepted product dispensing error	7
Insurance issue	7
Injection site urticaria	7
Injection site injury	7
Injection site exfoliation	7
ILL-DEFINED DISORDER	7
Hypertonia neonatal	7
HYPERREFLEXIA	7
HIV infection	7
Hernia	7
Gingival pain	7
Gestational hypertension	7
GASTROSCHISIS	7
GAMMA-GLUTAMYLTRANSFERASE INCREASED	7
FLUID INTAKE REDUCED	7
FLATULENCE	7
FACE OEDEMA	7
EYE PAIN	7
Expired product administered	7
EMBOLISM	7
Embolia cutis medicamentosa	7
ECZEMA	7
ECTOPIC PREGNANCY	7
DRUG LEVEL BELOW THERAPEUTIC	7
DRUG EXPOSURE VIA BREAST MILK	7
DROWNING	7
DISEASE PROGRESSION	7
DIABETIC KETOACIDOSIS	7
DELUSIONAL DISORDER, PERSECUTORY TYPE	7
Deafness neurosensory	7
DEAFNESS	7
Crime	7
CARDIAC FAILURE ACUTE	7
CANDIDIASIS	7
BREAST CANCER	7
Blood testosterone decreased	7
BLOOD ALKALINE PHOSPHATASE INCREASED	7
BLINDNESS	7
Bedridden	7
BACK DISORDER	7
ATRIAL FLUTTER	7
AMNIOTIC CAVITY INFECTION	7
Allergic reaction to excipient	7
ACUTE PULMONARY OEDEMA	7
ACUTE PSYCHOSIS	7
Ventricular tachycardia	6
Tongue erythema	6
Systemic lupus erythematosus	6
SPINAL DISORDER	6
Skin wound	6
SKIN INFECTION	6
SELF-MEDICATION	6
SCIATICA	6
Rotator cuff syndrome	6
REACTION TO DRUG EXCIPIENTS	6
PSYCHOMOTOR SKILLS IMPAIRED	6
Productive cough	6
Product size issue	6
POLYNEUROPATHY	6
PIERRE ROBIN SYNDROME	6
PETECHIAE	6
Personality change	6
PANIC REACTION	6
PANCREATIC CARCINOMA	6
OSTEITIS	6
Neonatal respiratory distress	6
NEEDLE TRACK MARKS	6
Nasal congestion	6
Narcolepsy	6
MYOSITIS	6
MULTIPLE SCLEROSIS	6
Multiple congenital abnormalities	6
MASS	6
MALIGNANT NEOPLASM PROGRESSION	6
Macrosomia	6
Liver function test increased	6
LIVEDO RETICULARIS	6
Lip blister	6
LACTIC ACIDOSIS	6
KIDNEY INFECTION	6
JOINT STIFFNESS	6
Intentional removal of drug delivery system by patient	6
IMPAIRED GASTRIC EMPTYING	6
IMMOBILE	6
ILEUS PARALYTIC	6
ILEUS	6
HYPOKINESIA	6
Hydronephrosis	6
HOMICIDAL IDEATION	6
HIP FRACTURE	6
HICCUPS	6
Herpes zoster	6
HEMIPARESIS	6
Head circumference abnormal	6
HAEMOPTYSIS	6
HAEMATOMA	6
GASTRITIS	6
GALLBLADDER DISORDER	6
Feeling drunk	6
EXTREMITY NECROSIS	6
Exposure via father	6
EPISTAXIS	6
ENERGY INCREASED	6
ENDOCARDITIS BACTERIAL	6
EATING DISORDER	6
EAR PAIN	6
Drug effect delayed	6
DISSEMINATED INTRAVASCULAR COAGULATION	6
Dermal absorption impaired	6
CYTOLYTIC HEPATITIS	6
Craniocerebral injury	6
Compression fracture	6
COMPLICATIONS OF MATERNAL EXPOSURE TO THERAPEUTIC DRUGS	6
Clumsiness	6
CLAVICLE FRACTURE	6
Cervical myelopathy	6
CAROTID ARTERY OCCLUSION	6
Cancer pain	6
BRUXISM	6
BRONCHOPNEUMONIA	6
BRAIN HERNIATION	6
BRAIN ABSCESS	6
BRADYCARDIA NEONATAL	6
BONE MARROW FAILURE	6
BLOOD GLUCOSE DECREASED	6
BLOOD CREATININE INCREASED	6
Attention deficit/hyperactivity disorder	6
Atrial septal defect	6
Arthropod bite	6
ARTERIAL THROMBOSIS LIMB	6
Application site infection	6
Application site induration	6
APPENDIX DISORDER	6
ANXIETY DISORDER	6
ANHEDONIA	6
AMENORRHOEA	6
ALCOHOL POISONING	6
AGEUSIA	6
AFFECT LABILITY	6
ABORTION	6
17 ketosteroids urine abnormal	6
WRONG DRUG ADMINISTERED	5
VOMITING PROJECTILE	5
Uterine disorder	5
URINE OUTPUT DECREASED	5
Umbilical cord around neck	5
Tubulointerstitial nephritis	5
TRISMUS	5
Tooth infection	5
Thyroid disorder	5
THIRST	5
Tachyphrenia	5
Suppressed lactation	5
STEVENS-JOHNSON SYNDROME	5
Splenic rupture	5
Spina bifida	5
SOMNAMBULISM	5
SKIN LACERATION	5
Shoulder operation	5
Self esteem decreased	5
SACROILIITIS	5
RETAINED PLACENTA OR MEMBRANES	5
RECTAL HAEMORRHAGE	5
Reaction to excipient	5
RASH MACULO-PAPULAR	5
PYELONEPHRITIS	5
PULSE ABSENT	5
Pulmonary hypertension	5
PSORIASIS	5
Prostatomegaly	5
Prostatitis	5
Product prescribing issue	5
Product preparation issue	5
Product dose omission issue	5
Product administered to patient of inappropriate age	5
PROCTALGIA	5
PRIAPISM	5
PHLEBITIS	5
PAROSMIA	5
PARKINSONISM	5
Pain of skin	5
PAIN IN JAW	5
OROPHARYNGEAL BLISTERING	5
ORAL MUCOSAL EXFOLIATION	5
Ocular hyperaemia	5
Noninfective gingivitis	5
NECK INJURY	5
MUSCULOSKELETAL CHEST PAIN	5
MULTI-ORGAN FAILURE	5
Mixed anxiety and depressive disorder	5
MENSTRUATION IRREGULAR	5
Medical observation	5
Medical device removal	5
Lyme disease	5
LOCAL SWELLING	5
Lip and/or oral cavity cancer	5
LIMB MALFORMATION	5
Limb discomfort	5
LEUKOPLAKIA	5
Labelled drug-drug interaction medication error	5
KNEE ARTHROPLASTY	5
INTESTINAL PERFORATION	5
Intervertebral disc protrusion	5
Intervertebral disc degeneration	5
INGUINAL HERNIA	5
Increased appetite	5
INCORRECT PRODUCT STORAGE	5
IMMUNE SYSTEM DISORDER	5
HYPOPHAGIA	5
Hypersensitivity pneumonitis	5
HEPATOCELLULAR INJURY	5
HEPATITIS TOXIC	5
HEPATITIS CHOLESTATIC	5
GINGIVAL DISORDER	5
Gastric disorder	5
GANGRENE	5
Foreign body reaction	5
FOETAL GROWTH RETARDATION	5
Fibrosis	5
FEEDING DISORDER	5
FAILURE TO THRIVE	5
FACIAL BONES FRACTURE	5
ENTEROBACTER INFECTION	5
ENCEPHALITIS	5
EMPHYSEMA	5
DYSTONIA	5
Drug screen false positive	5
Drug level fluctuating	5
DECREASED INTEREST	5
CORONARY ARTERY STENOSIS	5
COMMUNICATION DISORDER	5
CHOLECYSTITIS	5
Choking	5
CEREBRAL ISCHAEMIA	5
BRONCHITIS	5
BORDERLINE PERSONALITY DISORDER	5
BONE INFARCTION	5
BODY TEMPERATURE INCREASED	5
BLOOD PRESSURE FLUCTUATION	5
Blood pressure abnormal	5
BLOOD BILIRUBIN INCREASED	5
BLINDNESS TRANSIENT	5
BLADDER DILATATION	5
Bacteraemia	5
ARTERIAL OCCLUSIVE DISEASE	5
Anorgasmia	5
ANOREXIA	5
ALCOHOL USE	5
Acute coronary syndrome	5
Wrong product administered	4
WRIST FRACTURE	4
VISUAL FIELD DEFECT	4
Viral infection	4
VICTIM OF HOMICIDE	4
VENTRICULAR SEPTAL DEFECT	4
VENTRICULAR FIBRILLATION	4
Upper respiratory tract infection	4
Ulcer haemorrhage	4
TYPE 1 DIABETES MELLITUS	4
TUBERCULOSIS	4
Troponin T increased	4
Tricuspid valve replacement	4
TOXIC EPIDERMAL NECROLYSIS	4
TOOTH INJURY	4
Tooth abscess	4
Tonic clonic movements	4
Tongue eruption	4
Tibia fracture	4
THREATENED LABOUR	4
Therapeutic response increased	4
Therapeutic product effect delayed	4
Theft	4
SUPRAVENTRICULAR TACHYCARDIA	4
SUFFOCATION FEELING	4
Substance abuser	4
STUPOR	4
Splenomegaly	4
Spinal osteoarthritis	4
SPEECH DISORDER DEVELOPMENTAL	4
Soft tissue necrosis	4
SNORING	4
SMALL INTESTINAL OBSTRUCTION	4
Slow response to stimuli	4
SKIN WARM	4
SKIN ODOUR ABNORMAL	4
Skin abrasion	4
SINUS BRADYCARDIA	4
SENSORY LOSS	4
SENSORY DISTURBANCE	4
Sedation complication	4
RENAL EMBOLISM	4
Renal cancer	4
PYLORIC STENOSIS	4
PURPURA	4
PULSE ABNORMAL	4
Pulmonary artery stenosis congenital	4
Psychiatric decompensation	4
PROLONGED PREGNANCY	4
PROLONGED LABOUR	4
PRODUCT MEASURED POTENCY ISSUE	4
Product communication issue	4
POSTPARTUM HAEMORRHAGE	4
Poor quality product administered	4
Polyhydramnios	4
PNEUMONIA STAPHYLOCOCCAL	4
Pneumonia necrotising	4
Pharyngeal swelling	4
Pharyngeal disorder	4
Peripheral embolism	4
PERICARDIAL EFFUSION	4
Osteoporosis	4
Oral herpes	4
OEDEMA MOUTH	4
NYSTAGMUS	4
Neurotoxicity	4
Neuroleptic malignant syndrome	4
NEPHROTIC SYNDROME	4
Nephroangiosclerosis	4
Neonatal hypoxia	4
Muscle contractions involuntary	4
Multiple use of single-use product	4
Multiple fractures	4
MOTOR DYSFUNCTION	4
Micrognathia	4
METABOLIC DISORDER	4
Maternal exposure during breast feeding	4
Macrocytosis	4
LYMPHOMA	4
LUNG INFILTRATION	4
LIPASE INCREASED	4
Ligament rupture	4
Large intestine perforation	4
Lack of application site rotation	4
Lack of administration site rotation	4
IRRITABLE BOWEL SYNDROME	4
Intercepted drug dispensing error	4
Injection site scab	4
Injection site ischaemia	4
Infantile vomiting	4
Imprisonment	4
Hyporesponsive to stimuli	4
HYPOALBUMINAEMIA	4
Hypoacusis	4
HYPERTENSIVE CRISIS	4
HYPERPROLACTINAEMIA	4
Hyperkalaemia	4
HYPERBILIRUBINAEMIA	4
Hepatitis C virus test positive	4
HEPATIC STEATOSIS	4
Hearing impaired	4
Hangover	4
GROWTH RETARDATION	4
Gingival recession	4
Gingival bleeding	4
FOREIGN BODY	4
FOETAL HEART RATE DECREASED	4
Foetal heart rate abnormal	4
FOETAL ARRHYTHMIA	4
Flank pain	4
FINGER AMPUTATION	4
FIBROMYALGIA	4
FEELING OF DESPAIR	4
Facial paralysis	4
EYE MOVEMENT DISORDER	4
Electrocardiogram QRS complex prolonged	4
Ejaculation delayed	4
ECLAMPSIA	4
DRY GANGRENE	4
DRY EYE	4
DROOLING	4
DISSOCIATION	4
Device breakage	4
Detoxification	4
CORONARY ARTERY DISEASE	4
Congenital multiplex arthrogryposis	4
COLITIS	4
Clostridium difficile colitis	4
CLONUS	4
CIRRHOSIS ALCOHOLIC	4
Chronic kidney disease	4
Chronic hepatitis C	4
CHONDRODYSTROPHY	4
CHOKING SENSATION	4
Cerebral ventricle dilatation	4
CARPAL TUNNEL SYNDROME	4
CARDIOVASCULAR DISORDER	4
Cardio-respiratory distress	4
CARDIAC VALVE DISEASE	4
Cardiac valve abscess	4
Bundle branch block right	4
Bronchopneumopathy	4
Breech presentation	4
BRAIN CONTUSION	4
Bradyphrenia	4
Blood lactic acid increased	4
Blood disorder	4
Back injury	4
ARTERIOSCLEROSIS CORONARY ARTERY	4
Application site warmth	4
Application site pustules	4
Application site paraesthesia	4
Apnoea neonatal	4
AORTIC VALVE INCOMPETENCE	4
Amniotic fluid volume decreased	4
Alcohol detoxification	4
Administration site abscess sterile	4
Acute hepatitis C	4
ABDOMINAL PAIN LOWER	4
Wound secretion	3
Victim of chemical submission	3
VENOUS THROMBOSIS LIMB	3
VEIN DISORDER	3
Uterine haemorrhage	3
Urosepsis	3
Urine flow decreased	3
URINARY TRACT MALFORMATION	3
Type 2 diabetes mellitus	3
TRISOMY 21	3
Trigeminal neuralgia	3
TOXICOLOGIC TEST ABNORMAL	3
Tooth hypoplasia	3
Tongue pruritus	3
Tongue neoplasm malignant stage unspecified	3
Tongue injury	3
Tobacco poisoning	3
Taste disorder	3
SYSTEMIC INFLAMMATORY RESPONSE SYNDROME	3
SYSTEMIC CANDIDA	3
Swelling of eyelid	3
Streptococcal bacteraemia	3
STAPHYLOCOCCUS TEST POSITIVE	3
SPONDYLITIS	3
Splenic embolism	3
SKIN NODULE	3
Skin mass	3
Shock haemorrhagic	3
Sensory processing disorder	3
SENSATION OF FOREIGN BODY	3
SELF-INJURIOUS IDEATION	3
SECRETION DISCHARGE	3
Ruptured ectopic pregnancy	3
Rubber sensitivity	3
Retroplacental haematoma	3
RESPIRATORY TRACT INFECTION	3
Respiratory symptom	3
RESPIRATORY RATE INCREASED	3
RESPIRATORY PARALYSIS	3
RESPIRATION ABNORMAL	3
Renal dysplasia	3
Regurgitation	3
RASH VESICULAR	3
Quality of life decreased	3
Purpura fulminans	3
PULMONARY SEPSIS	3
Pulmonary hypoplasia	3
PULMONARY ARTERIAL HYPERTENSION	3
PSYCHOTIC BEHAVIOUR	3
Psychiatric symptom	3
Product monitoring error	3
Product leakage	3
Product label issue	3
Product distribution issue	3
Product contamination microbial	3
Product commingling	3
Product appearance confusion	3
Portal vein thrombosis	3
Poor sucking reflex	3
POLYARTHRITIS	3
PO2 DECREASED	3
PLACENTAL INSUFFICIENCY	3
Peritonitis	3
Peripheral venous disease	3
Peripheral vascular disorder	3
Peripheral coldness	3
Peripheral artery thrombosis	3
Penile necrosis	3
Pelvic pain	3
Patient uncooperative	3
PATHOLOGICAL FRACTURE	3
PARONYCHIA	3
Parkinson's disease	3
Papule	3
PAPILLOEDEMA	3
PANCREATITIS CHRONIC	3
Oral mucosal discolouration	3
OESOPHAGITIS	3
NUCLEAR MAGNETIC RESONANCE IMAGING BRAIN ABNORMAL	3
NORMOCHROMIC NORMOCYTIC ANAEMIA	3
NO THERAPEUTIC RESPONSE	3
Neonatal respiratory depression	3
NEONATAL INFECTION	3
Negative thoughts	3
Necrotising enterocolitis neonatal	3
MYOCARDIAL ISCHAEMIA	3
MUSCULOSKELETAL DISORDER	3
Musculoskeletal discomfort	3
Muscle fatigue	3
Mucosal ulceration	3
Middle insomnia	3
METABOLIC ENCEPHALOPATHY	3
MELAENA	3
MEDICATION RESIDUE	3
MECONIUM STAIN	3
Maternal exposure during delivery	3
LUNG NEOPLASM	3
LUNG INFECTION	3
LUNG CANCER METASTATIC	3
Lumbar vertebral fracture	3
LOWER RESPIRATORY TRACT INFECTION	3
LOSS OF EMPLOYMENT	3
LARYNGITIS	3
LACERATION	3
Knee operation	3
Joint injury	3
JOINT DISLOCATION	3
ISCHAEMIC HEPATITIS	3
INTERSTITIAL LUNG DISEASE	3
INTERNATIONAL NORMALISED RATIO INCREASED	3
Intentional misuse of drug delivery system	3
Injection site thrombosis	3
Injection site scar	3
Injection site pallor	3
Injection site nodule	3
Injection site granuloma	3
INDUCED LABOUR	3
Increased viscosity of upper respiratory secretion	3
Inappropriate schedule of product discontinuation	3
INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION	3
Inappropriate affect	3
IMPULSIVE BEHAVIOUR	3
Idiopathic intracranial hypertension	3
HYPOVOLAEMIA	3
HYPOTHYROIDISM	3
HYPOGONADISM	3
Hypocalcaemia	3
HYPERVIGILANCE	3
HYPERGAMMAGLOBULINAEMIA	3
Hydrocephalus	3
HOMICIDE	3
HIV TEST POSITIVE	3
Hepatosplenomegaly	3
HEPATOMEGALY	3
HEPATITIS C ANTIBODY POSITIVE	3
Hepatitis B	3
Hepatitis A	3
HEPATIC NEOPLASM MALIGNANT	3
Heart disease congenital	3
Head titubation	3
Hand fracture	3
Hallucination, tactile	3
HAEMOTHORAX	3
Haemorrhagic stroke	3
HAEMOLYTIC ANAEMIA	3
HAEMOGLOBIN DECREASED	3
HAEMODYNAMIC INSTABILITY	3
HAEMATURIA	3
Gout	3
GLOSSOPTOSIS	3
Glomerulonephritis membranoproliferative	3
GLAUCOMA	3
Gingival swelling	3
Gingival discomfort	3
GENERALISED ERYTHEMA	3
GENERAL PHYSICAL CONDITION ABNORMAL	3
GAZE PALSY	3
GASTROINTESTINAL OBSTRUCTION	3
GASTROENTERITIS	3
Gastric ulcer	3
GASTRIC HAEMORRHAGE	3
GASTRIC CANCER	3
GALACTORRHOEA	3
FUNGAL INFECTION	3
FOOD CRAVING	3
Foetal malnutrition	3
FOETAL HYPOKINESIA	3
Foetal heart rate disorder	3
Foetal heart rate deceleration abnormality	3
Fistula	3
Female sexual dysfunction	3
Feeding intolerance	3
Eye pruritus	3
EPIDERMAL NECROSIS	3
ENDOCARDITIS ENTEROCOCCAL	3
ENAMEL ANOMALY	3
Electrolyte imbalance	3
Economic problem	3
Ear neoplasm malignant	3
Drug withdrawal headache	3
Drug monitoring procedure not performed	3
Drug level abnormal	3
Drug effect variable	3
DRUG EFFECT PROLONGED	3
Diarrhoea neonatal	3
Developmental hip dysplasia	3
Delirium tremens	3
Decubitus ulcer	3
DECREASED ACTIVITY	3
Cyanosis neonatal	3
CSF PROTEIN INCREASED	3
Crohn's disease	3
CONVERSION DISORDER	3
Contraindicated product prescribed	3
Congenital genital malformation	3
Conduction disorder	3
Complication of device removal	3
Coma blister	3
Cleft lip	3
Circumstance or information capable of leading to medication error	3
CHORIOAMNIONITIS	3
Chemical submission	3
CHEMICAL INJURY	3
Cheilitis	3
CERVICOBRACHIAL SYNDROME	3
Cervical spinal stenosis	3
Cerebral atrophy	3
Cerebellar stroke	3
CAROTID ARTERY STENOSIS	3
CARDIOMEGALY	3
CARDIAC TAMPONADE	3
CACHEXIA	3
Bursitis	3
BURNS SECOND DEGREE	3
BURNING SENSATION MUCOSAL	3
Breast disorder	3
Bowen's disease	3
Blood prolactin increased	3
Blood potassium increased	3
BLOOD POTASSIUM DECREASED	3
BLOOD GLUCOSE ABNORMAL	3
BLOOD CULTURE POSITIVE	3
Blood carbon monoxide increased	3
BLOOD ALCOHOL INCREASED	3
BLINDNESS UNILATERAL	3
BLADDER DISORDER	3
BLADDER CANCER	3
BILIARY COLIC	3
BENIGN INTRACRANIAL HYPERTENSION	3
Autism spectrum disorder	3
Aura	3
Attention deficit hyperactivity disorder	3
ATAXIA	3
Aspergillus infection	3
Arthritis infective	3
Application site laceration	3
Application site haematoma	3
APPARENT DEATH	3
AORTIC ANEURYSM	3
ANURIA	3
ANOSMIA	3
ANAESTHETIC COMPLICATION	3
Amyotrophy	3
ALCOHOL INTERACTION	3
AIDS RELATED COMPLICATION	3
Administration site reaction	3
Acute cardiac event	3
Accident at work	3
ABDOMINAL HERNIA	3
Wrong patient received medication	2
Wrong dose	2
Wound necrosis	2
WHITE BLOOD CELL COUNT DECREASED	2
Weight gain poor	2
Viral upper respiratory tract infection	2
Victim of sexual abuse	2
Vestibular ischaemia	2
Vestibular disorder	2
Vertebral foraminal stenosis	2
Ventricular hypoplasia	2
VENTRICULAR EXTRASYSTOLES	2
VARICES OESOPHAGEAL	2
Uterine spasm	2
Uterine leiomyoma	2
UTERINE CONTRACTIONS DURING PREGNANCY	2
Urine odour abnormal	2
URINE ABNORMALITY	2
URINARY TRACT DISORDER	2
Urethritis	2
Upper-airway cough syndrome	2
Unintentional medical device removal	2
UNINTENDED PREGNANCY	2
Umbilical hernia	2
Umbilical cord abnormality	2
ULNAR NERVE INJURY	2
Ulna fracture	2
Type IV hypersensitivity reaction	2
Trisomy 18	2
Traumatic liver injury	2
Transient tachypnoea of the newborn	2
Toxic skin eruption	2
Toxic encephalopathy	2
Tooth extraction	2
Tongue exfoliation	2
TIC	2
THROMBOPHLEBITIS SUPERFICIAL	2
THROMBOPHLEBITIS SEPTIC	2
Therapy interrupted	2
Therapeutic response changed	2
Therapeutic product effect increased	2
Therapeutic nerve ablation	2
Testis cancer	2
Tendon disorder	2
Tachycardia foetal	2
Synovitis	2
Synovial cyst	2
SYNDACTYLY	2
Symptom recurrence	2
Suprapubic pain	2
Sunburn	2
Suicidal behaviour	2
Subileus	2
Subdural haemorrhage	2
Subarachnoid haemorrhage	2
Subacute endocarditis	2
STREPTOCOCCUS TEST POSITIVE	2
Streptococcal sepsis	2
Staring	2
SQUAMOUS CELL CARCINOMA	2
Sputum discoloured	2
SPLINTER HAEMORRHAGES	2
SPLEEN CONGESTION	2
SPINE MALFORMATION	2
Spinal pain	2
Spinal fusion surgery	2
Spinal cord compression	2
Spinal cord abscess	2
SPINAL COLUMN STENOSIS	2
Somatic delusion	2
Solar dermatitis	2
SOCIAL PROBLEM	2
Social anxiety disorder	2
Sleep terror	2
Skin texture abnormal	2
Skin injury	2
Skin hypertrophy	2
SKIN GRAFT	2
SKIN CANDIDA	2
Shoulder dystocia	2
Shoplifting	2
Selective eating disorder	2
Seborrhoea	2
Seasonal allergy	2
SCREAMING	2
SCIATIC NERVE NEUROPATHY	2
SCHIZOPHRENIFORM DISORDER	2
Schizoaffective disorder	2
Scab	2
Sarcopenia	2
RIGHT VENTRICULAR FAILURE	2
Rheumatic disorder	2
Rhesus incompatibility	2
Reversible cerebral vasoconstriction syndrome	2
Retroperitoneal abscess	2
RETINITIS	2
Respiratory syncytial virus infection	2
RENAL PAIN	2
Renal injury	2
RENAL ABSCESS	2
Rehabilitation therapy	2
RED BLOOD CELL SEDIMENTATION RATE INCREASED	2
RECTAL PROLAPSE	2
Reaction to colouring	2
REACTION TO AZO-DYES	2
RALES	2
RADIUS FRACTURE	2
Radial nerve palsy	2
PUPILLARY REFLEX IMPAIRED	2
PUPIL FIXED	2
Pupil constriction procedure	2
Pulseless electrical activity	2
Pulmonary tuberculosis	2
Pulmonary mass	2
Pulmonary fibrosis	2
PULMONARY ARTERY THROMBOSIS	2
Psychotic symptom	2
PSYCHOMOTOR RETARDATION	2
Psychiatric disorder prophylaxis	2
PSOAS ABSCESS	2
Prothrombin time prolonged	2
PROTHROMBIN LEVEL DECREASED	2
PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY	2
Product tampering	2
Product substitution	2
Product shape issue	2
Product residue present	2
Product packaging confusion	2
Product outer packaging issue	2
Product label confusion	2
PRODUCT FRIABLE	2
Product deposit	2
Product contamination physical	2
Product complaint	2
Product blister packaging issue	2
Product administration interrupted	2
Preterm premature rupture of membranes	2
Prescribed underdose	2
POST PROCEDURAL COMPLICATION	2
PORTAL HYPERTENSION	2
Poor weight gain neonatal	2
POLYURIA	2
POLYDACTYLY	2
PNEUMOPERITONEUM	2
Plicated tongue	2
PLATELET COUNT DECREASED	2
Plasma cell myeloma	2
Placental infarction	2
PITUITARY ENLARGEMENT	2
PHYSICAL ASSAULT	2
Photopsia	2
Pharyngitis	2
Phantom pain	2
Personality disorder	2
Persistent depressive disorder	2
Periorbital oedema	2
PERICARDITIS	2
Perforation	2
Peptic ulcer	2
Pemphigoid	2
PELVIC FRACTURE	2
PATENT DUCTUS ARTERIOSUS	2
Parkinsonian gait	2
PARESIS	2
PARAPARESIS	2
PANNICULITIS	2
Panic disorder	2
Palatal disorder	2
Painful respiration	2
Oxygen consumption decreased	2
Ovarian cyst	2
Otospondylomegaepiphyseal dysplasia	2
Osteopenia	2
Organ failure	2
Oral mucosa erosion	2
ORAL INFECTION	2
Opiates positive	2
OLIGURIA	2
OESOPHAGEAL RUPTURE	2
Oesophageal oedema	2
Oesophageal obstruction	2
Oesophageal disorder	2
Obesity	2
NON-CARDIOGENIC PULMONARY OEDEMA	2
Neutrophilia	2
Neurosis	2
Neurological symptom	2
Nerve injury	2
NERVE COMPRESSION	2
Nephritis	2
NEOPLASM PROGRESSION	2
NEONATAL ASPHYXIA	2
NECK DEFORMITY	2
Nasal dryness	2
Nasal discomfort	2
Muscle strain	2
MUSCLE INJURY	2
Multiple injuries	2
Mouth injury	2
MONOPLEGIA	2
MONOPARESIS	2
Moaning	2
Mixed liver injury	2
MITRAL VALVE PROLAPSE	2
Migration of implanted drug	2
METASTASES TO LYMPH NODES	2
METASTASES TO LIVER	2
Metastases to bone	2
Meningomyelocele	2
MECONIUM IN AMNIOTIC FLUID	2
Meconium aspiration syndrome	2
Maternal use of illicit drugs	2
Malignant melanoma	2
Male sexual dysfunction	2
Malabsorption from application site	2
MAJOR DEPRESSION	2
MACULOPATHY	2
LYMPHOPENIA	2
LYMPHADENITIS	2
Lupus-like syndrome	2
Loss of libido	2
LOCALISED OEDEMA	2
LOBAR PNEUMONIA	2
Liver transplant	2
Liver abscess	2
Live birth	2
LIP PAIN	2
Linear IgA disease	2
Limb reduction defect	2
LEUKAEMIA	2
Legal problem	2
LEG AMPUTATION	2
Left ventricular hypertrophy	2
Laryngomalacia	2
Language disorder	2
LACUNAR INFARCTION	2
Laboratory test abnormal	2
Knee deformity	2
KLEBSIELLA INFECTION	2
Kidney fibrosis	2
JOINT RANGE OF MOTION DECREASED	2
Jaw disorder	2
IRON DEFICIENCY ANAEMIA	2
INTRACRANIAL PRESSURE INCREASED	2
INTERVERTEBRAL DISC OPERATION	2
Intercepted product prescribing error	2
Intercepted drug prescribing error	2
Intentional medical device removal by patient	2
INJECTION SITE PHLEBITIS	2
Injection site paraesthesia	2
Injection site dermatitis	2
Injection site cyst	2
INJECTION	2
INFERTILITY	2
Infective spondylitis	2
INFANTILE APNOEIC ATTACK	2
Incorrect product dosage form administered	2
Incorrect drug administration rate	2
Illusion	2
Hypovitaminosis	2
Hypothermia neonatal	2
Hypothalamo-pituitary disorder	2
Hypoperfusion	2
Hypogeusia	2
HYPERTRIGLYCERIDAEMIA	2
Hypersensitivity vasculitis	2
HYPERPYREXIA	2
Hyperphagia	2
Hypernatraemia	2
Hyperleukocytosis	2
Hyperkeratosis	2
Hyperemesis gravidarum	2
HYPERCHOLESTEROLAEMIA	2
Hyperbilirubinaemia neonatal	2
Hyperammonaemia	2
HOSTILITY	2
Hospice care	2
Hormone level abnormal	2
Hodgkin's disease	2
HIGH ARCHED PALATE	2
Hernia congenital	2
HEPATITIS VIRAL	2
HEPATITIS D	2
HEPATITIS C POSITIVE	2
HEPATIC PAIN	2
Hepatic necrosis	2
Hepatic haemorrhage	2
Hepatic enzyme abnormal	2
Hepatic cancer	2
HEART RATE ABNORMAL	2
HAND DEFORMITY	2
Haemorrhagic anaemia	2
HAEMORRHAGE INTRACRANIAL	2
Haemorrhage in pregnancy	2
HAEMODIALYSIS	2
GRUNTING	2
GRIMACING	2
Gingival ulceration	2
Gastrointestinal perforation	2
GASTROINTESTINAL PAIN	2
GASTROINTESTINAL MOTILITY DISORDER	2
GASTROINTESTINAL HYPOMOTILITY	2
Gastric perforation	2
Gait inability	2
Furuncle	2
FUNGAL SKIN INFECTION	2
Functional gastrointestinal disorder	2
Frequent bowel movements	2
FORCEPS DELIVERY	2
Food poisoning	2
Food intolerance	2
Foetal exposure during delivery	2
Foetal cystic hygroma	2
FOETAL CARDIAC DISORDER	2
Fine motor skill dysfunction	2
Femoral artery aneurysm	2
Feeding disorder of infancy or early childhood	2
FALLOT'S TETRALOGY	2
FACIAL SPASM	2
FACIAL PALSY	2
Facial asymmetry	2
Eyelid ptosis	2
Eyelid oedema	2
EYE ROLLING	2
EXTRASYSTOLES	2
EXTRADURAL ABSCESS	2
Exposure via partner	2
Exposed bone in jaw	2
EXPIRED DRUG ADMINISTERED	2
Exomphalos	2
Eosinophilia	2
Enterococcal sepsis	2
Enteritis	2
Endocrine disorder	2
Encephalocele	2
EMPYEMA	2
Emotional poverty	2
EMBOLISM ARTERIAL	2
ELECTROCARDIOGRAM ST SEGMENT ELEVATION	2
Electrocardiogram repolarisation abnormality	2
Ejaculation failure	2
Ear discomfort	2
Ear canal stenosis	2
DYSPNOEA EXERTIONAL	2
Dysphemia	2
Dyshidrotic eczema	2
Ductus arteriosus premature closure	2
Dry throat	2
Drug withdrawal maintenance therapy	2
Drug tolerance increased	2
Drug eruption	2
Drug effect faster than expected	2
Drug dispensed to wrong patient	2
Drug dependence, antepartum	2
Drug administered to patient of inappropriate age	2
Documented hypersensitivity to administered product	2
Dizziness postural	2
Disturbance in social behaviour	2
Dissociative disorder	2
Dilatation ventricular	2
DIFFICULTY IN WALKING	2
Diaphragmatic hernia	2
Diabetic complication	2
DEXTROCARDIA	2
Device use error	2
Device issue	2
Device dislocation	2
DEVICE COLOUR ISSUE	2
DERMATITIS DIAPER	2
Dermatitis bullous	2
DEREALISATION	2
Depressive symptom	2
Delusion of reference	2
Defaecation urgency	2
CYTOMEGALOVIRUS INFECTION	2
CYSTITIS KLEBSIELLA	2
Cystitis	2
CSF white blood cell count increased	2
CORONARY ARTERY OCCLUSION	2
Conjunctival oedema	2
CONJUNCTIVAL HAEMORRHAGE	2
Congenital vesicoureteric reflux	2
CONGENITAL NOSE MALFORMATION	2
CONGENITAL MUSCULOSKELETAL ANOMALY	2
Congenital jaw malformation	2
CONGENITAL HAND MALFORMATION	2
CONGENITAL GENITOURINARY ABNORMALITY	2
Congenital cystic kidney disease	2
Conductive deafness	2
Concussion	2
Computerised tomogram thorax abnormal	2
COLON CANCER	2
Colitis ischaemic	2
Coeliac disease	2
Coating in mouth	2
Clostridium difficile infection	2
Circumoral oedema	2
Chorea	2
CERVICAL VERTEBRAL FRACTURE	2
CERVICAL DYSPLASIA	2
CEREBROVASCULAR SPASM	2
Cerebral palsy	2
Cerebral disorder	2
CEREBRAL CYST	2
CEREBELLAR INFARCTION	2
Cellulitis staphylococcal	2
Cell death	2
Catheterisation cardiac	2
Catatonia	2
Carpal tunnel decompression	2
Carditis	2
Cardiovascular symptom	2
Cardiopulmonary failure	2
CARDIAC HYPERTROPHY	2
Cardiac flutter	2
Burns third degree	2
Burning mouth syndrome	2
Breast cancer metastatic	2
Brain neoplasm	2
BRAIN DEATH	2
BRADYARRHYTHMIA	2
Botulism	2
BONE NEOPLASM MALIGNANT	2
Bone loss	2
Bone disorder	2
Blood triglycerides increased	2
Blood thyroid stimulating hormone increased	2
BLOOD TEST ABNORMAL	2
Blood pressure systolic increased	2
BLOOD PRESSURE DIASTOLIC DECREASED	2
BLOOD GLUCOSE FLUCTUATION	2
Blood cholesterol increased	2
Blood blister	2
Blister rupture	2
Bladder dysfunction	2
BASEDOW'S DISEASE	2
Bacterial sepsis	2
AUTOIMMUNE DISORDER	2
Atrioventricular block first degree	2
Asthenopia	2
Asterixis	2
Asocial behaviour	2
ARTHRITIS VIRAL	2
ARTERITIS	2
ARTERIOSCLEROSIS	2
Application site perspiration	2
APPLICATION SITE NECROSIS	2
Application site eczema	2
APPLICATION SITE BLEEDING	2
Appetite disorder	2
APPENDICITIS PERFORATED	2
APHAGIA	2
APGAR SCORE LOW	2
Aortic valve disease	2
Aortic dissection	2
Antiphospholipid syndrome	2
Ankylosing spondylitis	2
Ankyloglossia congenital	2
Anion gap	2
Aneurysm ruptured	2
ANAPHYLACTOID REACTION	2
Anal incontinence	2
Anaemia macrocytic	2
Anaemia folate deficiency	2
AMPUTATION	2
Amniotic fluid volume increased	2
Amniocentesis abnormal	2
AMINOACIDURIA	2
ALPHA HAEMOLYTIC STREPTOCOCCAL INFECTION	2
Alcohol problem	2
AGORAPHOBIA	2
Adrenergic syndrome	2
Administration site pain	2
Administration site irritation	2
Administration site dermatitis	2
Adenocarcinoma	2
ABORTION MISSED	2
Yellow skin	1
Wrong technique in device usage process	1
Wrong schedule	1
Wound infection fungal	1
Wound infection	1
WOUND DEHISCENCE	1
Wound abscess	1
Withdrawal hypertension	1
White coat hypertension	1
WHITE BLOOD CELLS URINE POSITIVE	1
Wheelchair user	1
WALLENBERG SYNDROME	1
WALDENSTROM'S MACROGLOBULINAEMIA	1
Vulvovaginal pain	1
Vulvovaginal injury	1
VULVAR DYSPLASIA	1
Vulvar basal cell carcinoma	1
Vomiting neonatal	1
Volvulus	1
VOLUME BLOOD DECREASED	1
VOCAL CORD PARALYSIS	1
Vocal cord disorder	1
VITREOUS HAEMORRHAGE	1
Vitreous floaters	1
VITREOUS DETACHMENT	1
VITREOUS DEGENERATION	1
VITH NERVE PARALYSIS	1
Vitamin D increased	1
Vitamin D decreased	1
Vitamin B12 deficiency	1
Vitamin B12 abnormal	1
Vitamin B1 deficiency	1
VISUAL DISTURBANCE	1
Visual agnosia	1
Vision abnormal neonatal	1
Visceral pain	1
Viral load increased	1
VIIth nerve paralysis	1
Victim of child abuse	1
Ventricular hypokinesia	1
Venous pressure jugular decreased	1
Vein collapse	1
VASODILATION PROCEDURE	1
Vasoconstriction	1
VASCULAR STENOSIS	1
Vascular purpura	1
Vascular pseudoaneurysm ruptured	1
Vascular operation	1
Vascular injury	1
Vascular access site rupture	1
Vascular access site haemorrhage	1
Varicella virus test positive	1
Varicella	1
Vanishing twin syndrome	1
Vaginal lesion	1
Vaginal infection	1
Vaginal discharge	1
UTERINE RUPTURE	1
Uterine prolapse	1
Uterine neoplasm	1
Uterine mass	1
Uterine hypotonus	1
Uterine contractions abnormal	1
UTERINE CERVIX STENOSIS	1
Use of accessory respiratory muscles	1
URINE OUTPUT INCREASED	1
URINE OSMOLARITY INCREASED	1
Urine alcohol test positive	1
URINARY TRACT OBSTRUCTION	1
Urinary retention postoperative	1
Urethral stenosis	1
Urethral pain	1
Ureteric dilatation	1
Upper respiratory tract congestion	1
Upper gastrointestinal perforation	1
Unintentional use for unapproved indication	1
Unable to afford prescribed medication	1
Umbilical cord prolapse	1
Ultrasound antenatal screen	1
Type I hypersensitivity	1
Twin pregnancy	1
Turner's syndrome	1
Tunnel vision	1
Tumour haemorrhage	1
Trichorrhexis	1
Traumatic haemothorax	1
Traumatic haematoma	1
TRAUMATIC BRAIN INJURY	1
TRANSPLANT FAILURE	1
TRANSMISSION OF DRUG VIA SEMEN	1
Transfusion	1
TRANCE	1
Tracheobronchitis	1
TRACHEO-OESOPHAGEAL FISTULA	1
TOXOPLASMA SEROLOGY POSITIVE	1
Tourette's disorder	1
Torticollis	1
Tooth deposit	1
Tooth delamination	1
TOOTH DECALCIFICATION	1
Tonsillitis	1
TONIC CONVULSION	1
Tongue pigmentation	1
Tongue oedema	1
Tongue movement disturbance	1
Tongue haemorrhage	1
Thyroidectomy	1
THYROID NEOPLASM	1
Thyroid hormones increased	1
THYROID CANCER	1
Thrombotic microangiopathy	1
Thrombocytosis	1
Thrombocytopenia neonatal	1
Throat cancer	1
Therapy partial responder	1
Therapeutic response unexpected with drug substitution	1
Therapeutic response delayed	1
Therapeutic drug monitoring analysis not performed	1
THERAPEUTIC AGENT TOXICITY	1
TETANUS	1
Testicular pain	1
Testicular disorder	1
TESTICULAR CANCER METASTATIC	1
Terminal dribbling	1
Tenosynovitis	1
Tendon rupture	1
Tendon injury	1
TENDERNESS	1
Temporomandibular joint syndrome	1
Temperature regulation disorder	1
TEMPERATURE INTOLERANCE	1
Telangiectasia	1
TEETHING	1
Teeth brittle	1
Tearfulness	1
Tardive dyskinesia	1
TABLET PHYSICAL ISSUE	1
SYMPATHECTOMY	1
Suspected product quality issue	1
Suspected product contamination	1
Superimposed pre-eclampsia	1
Superficial vein thrombosis	1
Suicide threat	1
Substance-induced mood disorder	1
Subdural hygroma	1
Subdural haematoma	1
Subdural abscess	1
Subcutaneous haematoma	1
Subcutaneous emphysema	1
SUBCLAVIAN VEIN THROMBOSIS	1
Subarachnoid haemorrhage neonatal	1
STRIDOR	1
Stress at work	1
Sternal fracture	1
Stenotrophomonas infection	1
Stem cell transplant	1
STATUS ASTHMATICUS	1
Starvation	1
Squamous cell carcinoma of lung	1
SPUTUM RETENTION	1
Sputum increased	1
Spontaneous bacterial peritonitis	1
Splenic cyst	1
Splenic artery aneurysm	1
Spinal stenosis	1
Spinal nerve stimulator implantation	1
Spinal fracture	1
Spinal decompression	1
Spinal cord ischaemia	1
Spinal cord infection	1
Somnolence neonatal	1
Somatic symptom disorder	1
Soft tissue infection	1
Soft tissue disorder	1
Social avoidant behaviour	1
Small intestinal stenosis	1
Sleep talking	1
Skull malformation	1
Skull fracture	1
Skin weeping	1
Skin tightness	1
Skin striae	1
Skin sensitisation	1
Skin oedema	1
SKIN MACERATION	1
SKIN INFLAMMATION	1
SKIN INDURATION	1
Skin haemorrhage	1
Skin fragility	1
SKIN DYSTROPHY	1
Sinus pain	1
Sinus node dysfunction	1
Sinus disorder	1
Sinus congestion	1
SINGLE UMBILICAL ARTERY	1
Single functional kidney	1
SIMPLE PARTIAL SEIZURES	1
SIMILAR REACTION ON PREVIOUS EXPOSURE TO DRUG	1
SILENT MYOCARDIAL INFARCTION	1
Sickle cell anaemia with crisis	1
Shunt infection	1
SHOULDER DEFORMITY	1
Short stature	1
Sexual inhibition	1
SEX CHROMOSOME ABNORMALITY	1
Serum serotonin increased	1
SEROLOGY POSITIVE	1
Septic pulmonary embolism	1
Septic necrosis	1
Septic endocarditis	1
Sepsis neonatal	1
SENSATION OF PRESSURE	1
SENSATION OF HEAVINESS	1
Seizure like phenomena	1
SCROTAL PAIN	1
SCROTAL DISORDER	1
SCOTOMA	1
Scoliosis	1
Scar excision	1
Sarcoidosis	1
Salmonellosis	1
Salivary gland enlargement	1
Salivary gland disorder	1
SALIVARY GLAND CANCER	1
Salivary duct inflammation	1
Sacroiliac fracture	1
RUPTURED CEREBRAL ANEURYSM	1
Rhinitis allergic	1
Rheumatoid nodule	1
Rhabdomyosarcoma	1
Reye's syndrome	1
Retinopathy solar	1
RETINAL HAEMORRHAGE	1
RETINAL DISORDER	1
RETINAL ARTERY STENOSIS	1
Retained products of conception	1
Respiratory tract oedema	1
Renal surgery	1
Renal mass	1
Renal haematoma	1
Renal fusion anomaly	1
Renal function test abnormal	1
Renal failure chronic	1
Renal cyst	1
RENAL CELL CARCINOMA	1
Refusal of treatment by patient	1
REFLEXES ABNORMAL	1
Red blood cell sedimentation rate abnormal	1
Red blood cell morphology abnormal	1
RED BLOOD CELL COUNT DECREASED	1
RECURRENT CANCER	1
RECTAL ULCER HAEMORRHAGE	1
RECTAL ULCER	1
Raynaud's phenomenon	1
Rash maculovesicular	1
Radiculopathy	1
Quadriplegia	1
Pyruvate kinase decreased	1
PYOTHORAX	1
PYOPNEUMOTHORAX	1
Pyelonephritis chronic	1
Pustular psoriasis	1
Purging	1
Pulmonary valve stenosis	1
Pulmonary valve incompetence	1
Pulmonary thrombosis	1
PULMONARY NECROSIS	1
PULMONARY INFARCTION	1
Pulmonary haemorrhage	1
PULMONARY GRANULOMA	1
PULMONARY ALVEOLAR HAEMORRHAGE	1
Pulmonary air leakage	1
Puerperal pyrexia	1
Psychological trauma	1
Psychogenic seizure	1
PSEUDOMONAS PSEUDOMALLEI INFECTION	1
PSEUDOMONAS INFECTION	1
PSEUDOMEMBRANOUS COLITIS	1
Proteinuria	1
PROTEIN-LOSING GASTROENTEROPATHY	1
Prostate cancer	1
Prolonged rupture of membranes	1
PROLACTIN-PRODUCING PITUITARY TUMOUR	1
Product selection error	1
Product lot number issue	1
Product label on wrong product	1
Product expiration date issue	1
Product container seal issue	1
Product barcode issue	1
Product availability issue	1
Procedural pneumothorax	1
Procedural hypotension	1
Procedural complication	1
Primary hyperthyroidism	1
Premenstrual headache	1
PREMATURE EJACULATION	1
Prehypertension	1
PREGNANCY WITH INJECTABLE CONTRACEPTIVE	1
Pregnancy test positive	1
Pregnancy on contraceptive	1
Posturing	1
Posture abnormal	1
Postpartum disorder	1
Postpartum depression	1
Postoperative wound complication	1
Postoperative abscess	1
Postmature baby	1
Postictal state	1
Post-traumatic neck syndrome	1
Post thrombotic syndrome	1
Post lumbar puncture syndrome	1
Post infection glomerulonephritis	1
Porphyrins urine increased	1
Porphyria	1
Poriomania	1
Porencephaly	1
POOR PERIPHERAL CIRCULATION	1
POLYTRAUMATISM	1
POLYSUBSTANCE DEPENDENCE	1
POLYDIPSIA	1
Polycythaemia neonatorum	1
POLYCYTHAEMIA	1
Polycystic ovaries	1
Polychondritis	1
Pneumothorax spontaneous	1
Pneumonia viral	1
PNEUMONIA PRIMARY ATYPICAL	1
PNEUMONIA PNEUMOCOCCAL	1
Pneumonia lipoid	1
Pneumonia klebsiella	1
Pneumonia bacterial	1
Pneumomediastinum	1
PNEUMOCYSTIS JIROVECI PNEUMONIA	1
Pneumococcal infection	1
Pneumocephalus	1
PNEUMATOSIS INTESTINALIS	1
PLEURITIC PAIN	1
Pleurisy	1
PLATELET COUNT INCREASED	1
PITTING OEDEMA	1
Pilonidal cyst	1
Physical product label issue	1
Physical disability	1
Physical deconditioning	1
Phonophobia	1
Phimosis	1
Pharyngitis streptococcal	1
Pharyngeal paraesthesia	1
Pharyngeal mass	1
Pharyngeal cancer	1
PHARMACEUTICAL PRODUCT COMPLAINT	1
PHAEOCHROMOCYTOMA	1
Pertussis	1
Personal relationship issue	1
Perseveration	1
PERONEAL NERVE PALSY	1
PERIVENTRICULAR LEUKOMALACIA	1
Peritoneal haemorrhage	1
PERITONEAL EFFUSION	1
Periprosthetic fracture	1
Peripheral sensorimotor neuropathy	1
PERIPHERAL PARALYSIS	1
Peripheral nerve operation	1
PERIPHERAL ARTERY DISSECTION	1
PERIPHERAL ARTERY ANEURYSM	1
Peripheral arterial occlusive disease	1
Periodontitis	1
Periodic limb movement disorder	1
PERINATAL BRAIN DAMAGE	1
PERICARDIAL HAEMORRHAGE	1
Pericardial disease	1
PERFORMANCE STATUS DECREASED	1
Penis injury	1
Penile infection	1
Pelvic floor dyssynergia	1
PELVIC ABSCESS	1
Paternal exposure timing unspecified	1
PATERNAL DRUGS AFFECTING FOETUS	1
Patella fracture	1
Passive smoking	1
PAROTITIS	1
Parotid gland enlargement	1
Parathyroid disorder	1
Parasomnia	1
PARANOID PERSONALITY DISORDER	1
Paraneoplastic syndrome	1
Paranasal cyst	1
Paraesthesia ear	1
PAPILLOMA VIRAL INFECTION	1
Pancreatitis relapsing	1
Pancreatic failure	1
PANCREATIC ENZYMES INCREASED	1
Pancreatic disorder	1
Pancreatic cystadenoma	1
Pancreatic cyst	1
Pancreatic carcinoma metastatic	1
Palatal oedema	1
Painful ejaculation	1
Oxygen saturation abnormal	1
Overweight	1
Overflow diarrhoea	1
Ovarian operation	1
Ovarian cystectomy	1
Ovarian cyst ruptured	1
OVARIAN CANCER	1
Osteoporotic fracture	1
Osteonecrosis of jaw	1
Osteomyelitis bacterial	1
OSLER'S NODES	1
OROPHARYNGEAL SWELLING	1
Oropharyngeal discomfort	1
Oral surgery	1
Oral pruritus	1
Oral fungal infection	1
Oral allergy syndrome	1
OPTIC NEURITIS	1
Oppositional defiant disorder	1
OILY SKIN	1
Oesophageal ulcer	1
Oesophageal stenosis	1
Oesophageal spasm	1
OESOPHAGEAL HAEMORRHAGE	1
Oesophageal carcinoma	1
Oesophageal adenocarcinoma	1
Oesophageal achalasia	1
Oedematous pancreatitis	1
OEDEMA GENITAL	1
OCULOGYRIC CRISIS	1
Ocular neoplasm	1
Ocular icterus	1
OCCULT BLOOD	1
Obstructive sleep apnoea syndrome	1
Obsessive-compulsive symptom	1
Obsessive-compulsive disorder	1
Nuchal rigidity	1
Normal newborn	1
Non-Hodgkin's lymphoma	1
Non-cardiac chest pain	1
NO ADVERSE EFFECT	1
Nipple pain	1
Neutropenia neonatal	1
Neurostimulator removal	1
Neuropsychiatric syndrome	1
Neuropsychiatric symptoms	1
Neuropathic arthropathy	1
Neuromuscular blockade	1
Neurodermatitis	1
Nephrosclerosis	1
Nephritic syndrome	1
NEOVASCULARISATION	1
Neoplasm	1
Neonatal respiratory failure	1
Neonatal hypotension	1
Neonatal hypoacusis	1
Neonatal hepatomegaly	1
Neonatal deafness	1
Neonatal complications of substance abuse	1
Neonatal behavioural syndrome	1
NEONATAL APNOEIC ATTACK	1
NEGLECT OF PERSONAL APPEARANCE	1
Necrosis of artery	1
Neck surgery	1
Neck mass	1
Near death experience	1
Nasal ulcer	1
Nasal obstruction	1
Nasal injury	1
Nasal inflammation	1
Nasal flaring	1
Myopathy	1
Myomectomy	1
MYOCLONIC EPILEPSY	1
Myocardial fibrosis	1
MYOCARDIAC ABSCESS	1
MYCOTIC ANEURYSM	1
Mycoplasma infection	1
MYCOBACTERIAL INFECTION	1
Mutism	1
Muscular dystrophy	1
Muscle spasticity	1
MUSCLE HYPERTROPHY	1
Muscle disorder	1
Muscle contracture	1
MUSCLE ATROPHY	1
MULTIPLE DRUG OVERDOSE INTENTIONAL	1
MULTIPLE DRUG OVERDOSE ACCIDENTAL	1
MULTIPLE DRUG OVERDOSE	1
MULTIPLE ALLERGIES	1
MULTI-ORGAN DISORDER	1
Motion sickness	1
Morphoea	1
Mononucleosis heterophile test positive	1
MOEBIUS II SYNDROME	1
MITOCHONDRIAL CYTOPATHY	1
Miliaria	1
Migraine with aura	1
Middle ear effusion	1
Micturition urgency	1
Micturition disorder	1
Microtia	1
MICROPENIS	1
Metrorrhagia	1
METHICILLIN-RESISTANT STAPHYLOCOCCAL AUREUS TEST POSITIVE	1
Methaemoglobinaemia	1
Metastatic malignant melanoma	1
METASTASIS	1
METASTASES TO THE MEDIASTINUM	1
Metastases to spine	1
Metastases to pleura	1
Metastases to neck	1
Metastases to central nervous system	1
Mesenteric artery embolism	1
MESANGIOPROLIFERATIVE GLOMERULONEPHRITIS	1
Menstrual disorder	1
Menorrhagia	1
Menopause	1
Meniscus injury	1
MENINGITIS VIRAL	1
Meningitis staphylococcal	1
Meningitis cryptococcal	1
Meningitis candida	1
Meningitis bacterial	1
Meniere's disease	1
MENDELSON'S SYNDROME	1
Medical induction of coma	1
Medical device implantation	1
MEDIAN NERVE INJURY	1
Measles	1
Maternal exposure timing unspecified	1
Maternal exposure before pregnancy	1
Mastitis	1
MARITAL PROBLEM	1
Marasmus	1
Manufacturing production issue	1
Male orgasmic disorder	1
Malabsorption from administration site	1
MACULE	1
MACROCEPHALY	1
Lymphocytosis	1
LYMPHOCYTE COUNT DECREASED	1
Lymphocele	1
LYMPHATIC DISORDER	1
LYMPHANGIECTASIA INTESTINAL	1
Lymphadenopathy mediastinal	1
LUNG CONSOLIDATION	1
LUNG ADENOCARCINOMA METASTATIC	1
LUMBAR SPINAL STENOSIS	1
LOWER RESPIRATORY TRACT INFLAMMATION	1
Loss of control of legs	1
Long QT syndrome	1
Listless	1
Lipomatosis	1
Lip oedema	1
Lip discolouration	1
Limb operation	1
Limb fracture	1
Limb deformity	1
Ligament sprain	1
Ligament injury	1
Lice infestation	1
Libido increased	1
LEFT VENTRICULAR DYSFUNCTION	1
Left ventricular dilatation	1
Laziness	1
LARYNGEAL OEDEMA	1
LARYNGEAL DYSPNOEA	1
Laryngeal dysplasia	1
Large intestinal obstruction	1
LABOUR PAIN	1
Klinefelter's syndrome	1
Jugular vein thrombosis	1
Joint hyperextension	1
Joint effusion	1
Joint destruction	1
Janeway lesion	1
IVTH NERVE PARALYSIS	1
ISCHAEMIC LIMB PAIN	1
INTUSSUSCEPTION	1
Intraductal proliferative breast lesion	1
INTRACRANIAL INJURY	1
Intracranial haematoma	1
Intracranial aneurysm	1
INTRACARDIAC THROMBUS	1
Intra-abdominal haematoma	1
INTESTINAL INFARCTION	1
Intestinal congestion	1
INTERTRIGO	1
International normalised ratio decreased	1
Internal haemorrhage	1
Intermenstrual bleeding	1
INTERCOSTAL RETRACTION	1
Intercepted product selection error	1
Intercepted medication error	1
Inner ear disorder	1
INJURY ASPHYXIATION	1
Injection site pustule	1
Injection site nerve damage	1
Injection site hypoaesthesia	1
Injection site hypertrophy	1
Inhibitory drug interaction	1
Inguinal hernia, obstructive	1
Infrequent bowel movements	1
Inferiority complex	1
Infective aneurysm	1
Infectious pleural effusion	1
INFECTED SKIN ULCER	1
Infected dermal cyst	1
INFARCTION	1
INFANTILE SPITTING UP	1
Infantile colic	1
Infantile apnoea	1
INCREASED BRONCHIAL SECRETION	1
Incorrect dosage administered	1
Incisional hernia	1
Inability to afford medication	1
Implant site swelling	1
Implant site pruritus	1
Implant site irritation	1
Implant site inflammation	1
Implant site infection	1
Implant site erythema	1
Impetigo	1
Impaired self-care	1
Impaired reasoning	1
Impaired healing	1
IMMUNOGLOBULINS DECREASED	1
Illogical thinking	1
IIIRD NERVE DISORDER	1
Idiosyncratic drug reaction	1
IDIOPATHIC THROMBOCYTOPENIC PURPURA	1
Idiopathic interstitial pneumonia	1
Iatrogenic injury	1
Hysterectomy	1
Hypozincaemia	1
Hypoventilation neonatal	1
Hypospadias	1
Hyposmia	1
Hyporeflexia	1
HYPOPLASTIC LEFT HEART SYNDROME	1
HYPOPITUITARISM FOETAL	1
HYPOMAGNESAEMIA	1
Hypogonadism male	1
Hypoglycaemia unawareness	1
Hypoaesthesia teeth	1
Hypertrophy of tongue papillae	1
Hypertonic bladder	1
HYPERTHYROIDISM	1
Hypertensive urgency	1
HYPERTENSIVE HEART DISEASE	1
Hypertensive emergency	1
HYPERTELORISM OF ORBIT	1
Hypersexuality	1
Hypermagnesaemia	1
Hyperlipidaemia	1
Hyperkinesia	1
Hyperchlorhydria	1
Hyperaesthesia teeth	1
HYGROMA COLLI	1
Humerus fracture	1
Human rhinovirus test positive	1
Hip surgery	1
HIP DYSPLASIA	1
Hip arthroplasty	1
High risk pregnancy	1
Heterotaxia	1
HERPES VIRUS INFECTION	1
Herpes simplex test positive	1
Herpes simplex	1
HEPATOCELLULAR DAMAGE	1
Hepatocellular carcinoma	1
HEPATITIS NON-A NON-B	1
Hepatitis fulminant	1
Hepatitis alcoholic	1
Hepatic fibrosis marker abnormal	1
Hepatic fibrosis	1
Hepatic embolisation	1
HEPATIC CYST	1
Hepatic cancer stage IV	1
Hemivertebra	1
Heat stroke	1
Heart valve replacement	1
HEART VALVE INCOMPETENCE	1
HEART INJURY	1
HEART ALTERNATION	1
Head lag	1
HALLUCINATION, OLFACTORY	1
Hair texture abnormal	1
Hair colour changes	1
Haemorrhoids	1
Haemorrhagic diathesis	1
Haemorrhage subcutaneous	1
Haemophilus infection	1
Haemophilia	1
HAEMATOTOXICITY	1
Haematoma muscle	1
GUILLAIN-BARRE SYNDROME	1
GROIN PAIN	1
Grip strength decreased	1
GRIEF REACTION	1
Granulomatosis with polyangiitis	1
GRANULOMA	1
GRANULOCYTOSIS	1
GRANULOCYTOPENIA	1
GRAFT INFECTION	1
Glomerulonephritis chronic	1
GLOMERULAR FILTRATION RATE DECREASED	1
Glassy eyes	1
GLASGOW COMA SCALE	1
Gingivitis	1
Gingival injury	1
GINGIVAL INFECTION	1
Gingival erythema	1
Gingival erosion	1
Gingival blister	1
Genitourinary symptom	1
GENITAL HERPES	1
Generalised anxiety disorder	1
Gastrointestinal sounds abnormal	1
Gastrointestinal infection	1
Gastrointestinal hypermotility	1
Gastrointestinal erosion	1
Gastrointestinal bacterial infection	1
Gastroenteritis viral	1
Gastric ulcer perforation	1
GASTRIC HYPOMOTILITY	1
Gastric dilatation	1
GALLBLADDER PAIN	1
Gallbladder operation	1
FUSOBACTERIUM INFECTION	1
FUNISITIS	1
FUNGAL ENDOCARDITIS	1
Frustration tolerance decreased	1
Frustration	1
Foreign body ingestion	1
Foot operation	1
Food aversion	1
FOLLICULITIS	1
Foetal placental thrombosis	1
FOETAL MOVEMENTS DECREASED	1
Foetal macrosomia	1
Foetal heart rate increased	1
Foetal heart rate deceleration	1
FOETAL DISORDER	1
Foetal chromosome abnormality	1
Foetal anticonvulsant syndrome	1
Foetal alcohol syndrome	1
FOAMING AT MOUTH	1
FLAT AFFECT	1
FLASHBACK	1
FILARIASIS	1
Fibula fracture	1
Fibromatosis	1
FIBROCYSTIC BREAST DISEASE	1
Fibrin D dimer increased	1
Fever neonatal	1
Feelings of worthlessness	1
Feeling guilty	1
Febrile convulsion	1
Fear of death	1
False positive investigation result	1
False labour	1
Fallopian tube leiomyoma	1
Failure of child resistant product closure	1
Failure of child resistant mechanism for pharmaceutical product	1
Failed trial of labour	1
Faeces soft	1
Faecalith	1
Faecal incontinence	1
Faecal disimpaction	1
FACTOR VIII DEFICIENCY	1
Factor V Leiden mutation	1
Facial pain	1
FACIAL DYSMORPHISM	1
Fabry's disease	1
Eye penetration	1
EYE INJURY	1
EYE INFECTION FUNGAL	1
Eye infection bacterial	1
Eye infection	1
Eye disorder	1
EXUDATIVE RETINOPATHY	1
EXTRAVASATION	1
EXPOSURE VIA SEMEN	1
Exposure to extreme temperature	1
Explorative laparotomy	1
Exercise tolerance decreased	1
EXERCISE ELECTROCARDIOGRAM ABNORMAL	1
Excessive eye blinking	1
Ex-drug abuser	1
Evans syndrome	1
Essential hypertension	1
ESCHERICHIA URINARY TRACT INFECTION	1
Escherichia infection	1
Erythrosis	1
ERYTHROCYANOSIS	1
Erythema of eyelid	1
ERUCTATION	1
Erection increased	1
EPSTEIN-BARR VIRUS INFECTION	1
Epigastric discomfort	1
Epidural injection	1
Epicondylitis	1
EOSINOPHILIC PNEUMONIA	1
Enterobacter test positive	1
Endocarditis candida	1
Encephalopathy neonatal	1
Encephalomalacia	1
ENCEPHALITIS VIRAL	1
Encephalitis fungal	1
Emergency care examination	1
ELECTROENCEPHALOGRAM ABNORMAL	1
ELECTROCARDIOGRAM U-WAVE ABNORMALITY	1
ELECTROCARDIOGRAM T WAVE INVERSION	1
Electrocardiogram T wave abnormal	1
ELECTROCARDIOGRAM ST-T SEGMENT ABNORMAL	1
Electrocardiogram ST segment abnormal	1
Electrocardiogram QT interval abnormal	1
Electrocardiogram change	1
Edentulous	1
Ecchymosis	1
Ear pruritus	1
Ear injury	1
Ear infection	1
EAR HAEMORRHAGE	1
Ear disorder	1
Ear deformity acquired	1
DYSTHYMIC DISORDER	1
Dyspnoea at rest	1
Dysmenorrhoea	1
DYSLIPIDAEMIA	1
Dyslexia	1
DYSLALIA	1
Dyschezia	1
DYSAESTHESIA	1
Dwarfism	1
Duodenal atresia	1
Drug withdrawal convulsions	1
Drug tolerance decreased	1
Drug titration error	1
Drug therapeutic incompatibility	1
Drug resistance	1
Drug reaction with eosinophilia and systemic symptoms	1
Drug monitoring procedure incorrectly performed	1
Drug metabolising enzyme decreased	1
Drug level changed	1
DRUG LEVEL ABOVE THERAPEUTIC	1
Drug delivery system malfunction	1
Double ureter	1
Diverticulitis	1
DISUSE SYNDROME	1
Disturbance in sexual arousal	1
Disseminated cryptococcosis	1
Dislocation of vertebra	1
DISINHIBITION	1
Discoloured vomit	1
DiGeorge's syndrome	1
DIET REFUSAL	1
DIABETIC END STAGE RENAL DISEASE	1
DIABETIC COMA	1
Diabetes mellitus inadequate control	1
Diabetes insipidus	1
Device malfunction	1
Device difficult to use	1
Device computer issue	1
Developmental regression	1
Detrusor sphincter dyssynergia	1
Dermatitis exfoliative generalised	1
Dermatitis exfoliative	1
DERMATITIS ATOPIC	1
Dermal absorption increased	1
Depression suicidal	1
DEPERSONALISATION	1
Denture wearer	1
Dental discomfort	1
DENERVATION ATROPHY	1
DEMYELINATION	1
Delusional disorder, unspecified type	1
Delivery	1
DELAYED RECOVERY FROM ANAESTHESIA	1
Deformity	1
Decreased eye contact	1
Deafness bilateral	1
Daydreaming	1
CYTOTOXIC OEDEMA	1
Cytogenetic analysis abnormal	1
Cyst	1
Cutaneous symptom	1
CULTURE TISSUE SPECIMEN POSITIVE	1
CULTURE POSITIVE	1
CSF TEST ABNORMAL	1
CSF PRESSURE INCREASED	1
CRYPTOGENIC CIRRHOSIS	1
Craniofacial fracture	1
CORYNEBACTERIUM INFECTION	1
Convulsive threshold lowered	1
CONTRAINDICATION TO MEDICAL TREATMENT	1
Contraindicated drug prescribed	1
Contact stomatitis	1
Congenital scoliosis	1
Congenital pneumonia	1
Congenital naevus	1
Congenital melanocytic naevus	1
Congenital megaureter	1
CONGENITAL INTESTINAL MALFORMATION	1
Congenital hydronephrosis	1
Congenital hydrocephalus	1
CONGENITAL HEPATOBILIARY ANOMALY	1
Congenital hearing disorder	1
Congenital foot malformation	1
Congenital cerebrovascular anomaly	1
Congenital aortic anomaly	1
Compulsive hoarding	1
COMPLICATION OF PREGNANCY	1
Complication associated with device	1
COMA HEPATIC	1
Colonic pseudo-obstruction	1
Colon operation	1
Colon cancer recurrent	1
Colon cancer metastatic	1
Colloid brain cyst	1
COLLAPSE OF LUNG	1
Colectomy	1
Cold-stimulus headache	1
Clubbing	1
Clonic convulsion	1
CLINODACTYLY	1
CLEFT UVULA	1
Chronic sinusitis	1
CHRONIC OBSTRUCTIVE AIRWAYS DISEASE	1
CHRONIC MYELOMONOCYTIC LEUKAEMIA	1
Chronic inflammatory demyelinating polyradiculoneuropathy	1
Chronic hepatic failure	1
CHROMOSOMAL DELETION	1
Choroiditis	1
CHORDAE TENDINAE RUPTURE	1
Chondrocalcinosis pyrophosphate	1
Chondrocalcinosis	1
CHOLESTATIC PRURITUS	1
Cholestatic liver injury	1
Cholecystitis chronic	1
Cholecystitis acute	1
Cholangitis acute	1
Childhood disintegrative disorder	1
Cheyne-Stokes respiration	1
Chemical burn of gastrointestinal tract	1
Chemical burn	1
Cervix operation	1
CERVIX DISORDER	1
Cervix carcinoma stage 0	1
Cervical radiculopathy	1
CERVICAL INCOMPETENCE	1
CEREBROVASCULAR INSUFFICIENCY	1
Cerebrovascular disorder	1
Cerebrovascular arteriovenous malformation	1
Cerebrospinal fluid leakage	1
Cerebral ventricle collapse	1
CEREBRAL PERFUSION PRESSURE DECREASED	1
Cerebral artery thrombosis	1
Cerebral artery occlusion	1
Cerebral artery embolism	1
Cerebellar haemorrhage	1
Cerebellar atrophy	1
CEPHALO-PELVIC DISPROPORTION	1
Central sleep apnoea syndrome	1
CENTRAL NERVOUS SYSTEM NEOPLASM	1
CENTRAL NERVOUS SYSTEM LESION	1
Catheter site infection	1
Catheter site extravasation	1
Cataract	1
CAROTID ARTERY DISSECTION	1
Cardiogenic shock	1
Cardiac valve replacement complication	1
Cardiac pacemaker insertion	1
CARDIAC FIBRILLATION	1
Cardiac failure chronic	1
Cardiac dysfunction	1
CARDIAC DEATH	1
Carbon dioxide decreased	1
Caput succedaneum	1
CAPILLARY DISORDER	1
Candida test positive	1
Candida osteomyelitis	1
Candida endophthalmitis	1
Cancer surgery	1
CAMPTODACTYLY CONGENITAL	1
Camptocormia	1
CALCULUS URINARY	1
CALCULUS URETHRAL	1
Calciphylaxis	1
Butterfly rash	1
Burn oral cavity	1
Bundle branch block left	1
BRONCHIOLITIS	1
Bronchiectasis	1
Bronchial obstruction	1
BRONCHIAL CARCINOMA	1
Brief psychotic disorder with marked stressors	1
BREECH DELIVERY	1
BREATH SOUNDS ABNORMAL	1
Breath odour	1
BREAST PAIN	1
Breast milk substitute intolerance	1
Breast feeding	1
Breast cancer recurrent	1
Breast calcifications	1
Brain stem stroke	1
Brain stem infarction	1
BRAIN NATRIURETIC PEPTIDE INCREASED	1
Bradykinesia	1
Brachiocephalic vein thrombosis	1
Brachial plexus injury	1
BOWENOID PAPULOSIS	1
Boredom	1
BONE NEOPLASM	1
Bone marrow disorder	1
Bone graft	1
Bone cancer	1
Bone abscess	1
Body height decreased	1
Blood urine present	1
Blood urea increased	1
Blood thyroid stimulating hormone abnormal	1
Blood testosterone abnormal	1
Blood sodium abnormal	1
BLOOD PRESSURE SYSTOLIC DECREASED	1
Blood pressure diastolic increased	1
Blood magnesium increased	1
Blood magnesium decreased	1
BLOOD IMMUNOGLOBULIN G INCREASED	1
Blood folate decreased	1
Blood creatinine abnormal	1
Blood creatine increased	1
Blood cholesterol abnormal	1
BLOOD CALCIUM DECREASED	1
BLOOD AMYLASE INCREASED	1
Blister infected	1
BLINDNESS CORTICAL	1
Blindness congenital	1
Blighted ovum	1
BLEPHAROPHIMOSIS	1
Blast injury	1
Bladder prolapse	1
Bladder pain	1
Bladder irritation	1
Bipolar I disorder	1
BIOPSY LUNG ABNORMAL	1
BINOCULAR EYE MOVEMENT DISORDER	1
BILIARY DILATATION	1
BILIARY CIRRHOSIS PRIMARY	1
Beta haemolytic streptococcal infection	1
Benign prostatic hyperplasia	1
Benign hydatidiform mole	1
Belligerence	1
Basal ganglia haematoma	1
Basal cell carcinoma	1
BACTERIAL TOXAEMIA	1
BACILLUS INFECTION	1
Bacillus bacteraemia	1
B-CELL LYMPHOMA	1
AZOOSPERMIA	1
Aversion	1
Autosomal chromosome anomaly	1
Autonomic neuropathy	1
AUTOMATISM, COMMAND	1
Autoinflammatory disease	1
Autoimmune arthritis	1
Atypical pneumonia	1
Atypical haemolytic uraemic syndrome	1
Attention-seeking behaviour	1
ATRIOVENTRICULAR BLOCK	1
ATELECTASIS	1
Astigmatism	1
Arthropod sting	1
ARTHRITIS REACTIVE	1
ARTERIAL THROMBOSIS	1
ARTERIAL RUPTURE	1
Arterial haemorrhage	1
Arterial disorder	1
Arrested labour	1
Arnold-Chiari malformation	1
ARM AMPUTATION	1
Application site wound	1
Application site oedema	1
Application site mass	1
Application site hypoaesthesia	1
Application site atrophy	1
Apnoeic attack	1
Aphthous stomatitis	1
Aphonia	1
Apgar score abnormal	1
Aortic valve stenosis	1
Aortic valve prolapse	1
AORTIC STENOSIS	1
AORTIC NECROSIS	1
Aortic intramural haematoma	1
Aortic disorder	1
Antisocial personality disorder	1
Antinuclear antibody positive	1
ANTIMICROBIAL SUSCEPTIBILITY TEST RESISTANT	1
ANTICONVULSANT DRUG LEVEL DECREASED	1
ANTEPARTUM HAEMORRHAGE	1
ANOXIC ENCEPHALOPATHY	1
ANOXIA	1
Anorectal disorder	1
Anorectal discomfort	1
Anomaly of external ear congenital	1
Anogenital dysplasia	1
Anion gap increased	1
Anion gap abnormal	1
Angular cheilitis	1
ANGIONEUROTIC OEDEMA	1
Angina unstable	1
Analgesic drug level increased	1
Anal fistula	1
Anal atresia	1
ANAESTHESIA REVERSAL	1
ANAEMIA HAEMOLYTIC AUTOIMMUNE	1
Amylase increased	1
Amniotic infection syndrome of Blane	1
Amniotic cavity disorder	1
Amniorrhoea	1
AMMONIA INCREASED	1
Amblyopia	1
AMAUROSIS FUGAX	1
Alveolar lung disease	1
Allergy to metals	1
Allergy to arthropod sting	1
Alcoholic	1
Alcohol use disorder	1
ALCOHOL REHABILITATION	1
AKATHISIA	1
Agranulocytosis	1
Aerophobia	1
Adrenal insufficiency neonatal	1
Adrenal haemorrhage	1
Adrenal adenoma	1
Administration site wound	1
Administration site ulcer	1
Administration site injury	1
Administration site inflammation	1
Administration site hypertrophy	1
Administration site discomfort	1
Administration site abscess	1
ADJUSTMENT DISORDER	1
Adjacent segment degeneration	1
Acute stress disorder	1
Acute lymphocytic leukaemia	1
Acute lung injury	1
ACUTE HIV INFECTION	1
Acute hepatitis B	1
ACUTE FATTY LIVER OF PREGNANCY	1
ACUTE ENDOCARDITIS	1
ACUTE ABDOMEN	1
Acoustic neuroma	1
ACNE CYSTIC	1
ACINETOBACTER INFECTION	1
Acetonaemia	1
Accidental underdose	1
ACCIDENTAL NEEDLE STICK	1
Accidental exposure to product packaging by child	1
Accelerated hypertension	1
Abulia	1
Abscess neck	1
Abscess intestinal	1
Abscess fungal	1
ABSCESS BACTERIAL	1
ABNORMAL WEIGHT GAIN	1
ABNORMAL PALMAR/PLANTAR CREASES	1
ABNORMAL LOSS OF WEIGHT	1
Abnormal labour	1
Abnormal clotting factor	1
Abdominal wall haematoma	1
Abdominal wall cyst	1
Abdominal wall anomaly	1
Abdominal tenderness	1
Abdominal rigidity	1
ABDOMINAL REBOUND TENDERNESS	1
Abdominal injury	1
Abdominal abscess	1

Filtered ChEMBL targets:

Target UniProtKB ID	Activity in nm	Target Name	Target gene
P35372	0.09	Mu-type opioid receptor	OPRM_HUMAN
P41143	1.15	Delta-type opioid receptor	OPRD_HUMAN
P41145	0.04	Kappa-type opioid receptor	OPRK_HUMAN
P41146	77	Nociceptin receptor	OPRX_HUMAN
Q12809	7943.28	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN

Toxicity information:

Toxicity class:	4
Toxicity type:	respiratory
LD50:	359 mg/kg

External links:

ChEBML:	CHEMBL511142
DrugBank:	DB00921