Withdrawn ID: | w199 |
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Canonical SMILES: | |
Standard InChI: | |
Standard InChIKey: | |
ATC class(es): | G02CB01 |
N04BC01 | |
Molecular Formula: | C33H44BrN5O8S |
Molweight: | 750.71 |
Withdrawn due to drug safety reasons: | Yes |
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First approved: | 1976 |
First death: | 1995 |
First withdrawn: | 1994 |
Last withdrawn: | 1994 |
Reference: | https://www.ncbi.nlm.nih.gov/pubmed/23476663 |
Target UniProtKB ID | Activity in nm | Target Name | Target gene |
---|---|---|---|
O75496 | 7079.5 | Geminin | GEMI_HUMAN |
P10636 | 7079.5 | Microtubule-associated protein tau | TAU_HUMAN |
Toxicity class: | 4 |
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Toxicity type: | neurological |
LD50: | 800 mg/kg |
ChEBML: | CHEMBL1200503 |
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DrugBank: | DB01200 |