Amfepramone Hydrochloride
General information:
| Withdrawn ID: | w187 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | A08AA03 |
| Molecular Formula: | C13H19NO |
| Molweight: | 205.296 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First approved: | 1971 |
| First withdrawn: | 2000 |
| Last withdrawn: | 2000 |
| Reference: | https://www.ncbi.nlm.nih.gov/pubmed/3557542 |
Side-effects:
| Total reported cases (submitted by medical professionals) with Amfepramone Hydrochloride as primary suspect: | 3 |
|---|
Reported final outcomes:
| Hospitalization (initial or prolonged): | 3 |
|---|---|
| Intervention required to prevent permanent impairment/damage: | 1 |
Reported side-effects:
| Side-effect | Case number |
|---|---|
| WHITE BLOOD CELL COUNT INCREASED | 1 |
| WHITE BLOOD CELL COUNT DECREASED | 1 |
| VOMITING | 1 |
| REBOUND EFFECT | 1 |
| PULMONARY HYPERTENSION | 1 |
| NEUTROPHIL COUNT INCREASED | 1 |
| NEUTROPHIL COUNT DECREASED | 1 |
| MEDICATION ERROR | 1 |
| Duodenitis | 1 |
| DRUG WITHDRAWAL SYNDROME | 1 |
| DRUG TOXICITY | 1 |
| Diabetic ketoacidosis | 1 |
| DEPRESSION | 1 |
Toxicity information:
| Toxicity class: | 3 |
|---|---|
| Toxicity type: | cardiovascular |
| LD50: | 225 mg/kg |
External links:
| ChEBML: | CHEMBL1194666 |
|---|---|
| DrugBank: | DB00937 |