Nialamide
General information:
| Withdrawn ID: | w94 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | N06AF02 |
| Molecular Formula: | C16H18N4O2 |
| Molweight: | 298.34 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First withdrawn: | 1974 |
| Last withdrawn: | 1983 |
| Reference: | https://www.ncbi.nlm.nih.gov/pubmed/23934415 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| B2RXH2 | 8912.5 | Lysine-specific demethylase 4E | KDM4E_HUMAN |
| P02545 | 7079.5 | Prelamin-A/C | LMNA_HUMAN |
| P16473 | 6309.6 | Thyrotropin receptor | TSHR_HUMAN |
| Q16637 | 3548.1 | Survival motor neuron protein | SMN_HUMAN |
Toxicity information:
| Toxicity class: | 4 |
|---|---|
| Toxicity type: | hepatic |
| LD50: | 590 mg/kg |
External links:
| ChEBML: | CHEMBL1256841 |
|---|---|
| DrugBank: | DB04820 |