Dithiazanine iodide
General information:
| Withdrawn ID: | w91 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | A |
| Molecular Formula: | C23H23IN2S2 |
| Molweight: | 518.477 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First death: | 1960 |
| First withdrawn: | 1964 |
| Last withdrawn: | 1979 |
| Reference: | https://www.ncbi.nlm.nih.gov/pubmed/21574210 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| O15118 | 281.8 | NPC intracellular cholesterol transporter 1 | NPC1_HUMAN |
| P02545 | 4466.8 | Prelamin-A/C | LMNA_HUMAN |
| P10636 | 3981.1 | Microtubule-associated protein tau | TAU_HUMAN |
| P35222 | 3730 | Catenin beta-1 | CTNB1_HUMAN |
| P51151 | 316.2 | Ras-related protein Rab-9A | RAB9A_HUMAN |
| Q16637 | 1000 | Survival motor neuron protein | SMN_HUMAN |
| Q6W5P4 | 7943.3 | Neuropeptide S receptor | NPSR1_HUMAN |
Toxicity information:
| Toxicity class: | 1 |
|---|---|
| Toxicity type: | cardiovascular |
| LD50: | 2.55 mg/kg |
External links:
| ChEBML: | CHEMBL421701 |
|---|---|
| DrugBank: |