Alpidem
General information:
| Withdrawn ID: | w70 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | N |
| Molecular Formula: | C21H23Cl2N3O |
| Molweight: | 404.333 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First approved: | 1991 |
| First death: | 1994 |
| First withdrawn: | 1994 |
| Last withdrawn: | 1994 |
| Reference: | https://www.ncbi.nlm.nih.gov/pubmed/21574210 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| O95342 | 9200 | Bile salt export pump | ABCBB_HUMAN |
| P30536 | 0.5 | Translocator protein | TSPO_HUMAN |
Toxicity information:
| Toxicity class: | 4 |
|---|---|
| Toxicity type: | hepatic |
| LD50: | 695 mg/kg |
External links:
| ChEBML: | CHEMBL54349 |
|---|---|
| DrugBank: |