Etretinate


w53



General information:


Withdrawn ID: w53
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es): D05BB01
Molecular Formula: C23H30O3
Molweight: 354.483



Withdrawal information:


Withdrawn due to drug safety reasons:Yes
First approved: 1986
First withdrawn: 1989
Last withdrawn: 1989
Reference: https://www.ncbi.nlm.nih.gov/pubmed/21574210



Side-effects:

Total reported cases (submitted by medical professionals) with Etretinate as primary suspect: 3


Reported final outcomes:
Death: 3
Hospitalization (initial or prolonged): 2
Life-Threatening condition: 2
Disability: 1


Reported side-effects:
Side-effect Case number
DEATH2
SEPSIS1
RENAL FAILURE ACUTE1
PANCYTOPENIA1
OESOPHAGEAL CARCINOMA1





Toxicity information:

Toxicity class: 5
Toxicity type: reproductive
LD50: 4000 mg/kg



External links:

ChEBML: CHEMBL464
DrugBank: DB00926