Levamisole
General information:
| Withdrawn ID: | w51 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | P02CE01 |
| Molecular Formula: | C11H12N2S |
| Molweight: | 204.291 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First approved: | 1990 |
| First withdrawn: | 1999 |
| Last withdrawn: | 1999 |
| Reference: | https://www.ncbi.nlm.nih.gov/pubmed/7091125 |
Side-effects:
| Total reported cases (submitted by medical professionals) with Levamisole as primary suspect: | 11 |
|---|
Reported final outcomes:
| Hospitalization (initial or prolonged): | 5 |
|---|---|
| Congenital anomaly: | 4 |
| Death: | 3 |
| Intervention required to prevent permanent impairment/damage: | 1 |
| Life-Threatening condition: | 1 |
| Disability: | 1 |
Reported side-effects:
| Side-effect | Case number |
|---|---|
| PYREXIA | 4 |
| DRUG EXPOSURE DURING PREGNANCY | 3 |
| AGRANULOCYTOSIS | 3 |
| TOXICITY TO VARIOUS AGENTS | 3 |
| SYNDACTYLY | 3 |
| SPINA BIFIDA | 3 |
| CRYPTORCHISM | 3 |
| ACCIDENTAL EXPOSURE | 2 |
| CONGENITAL GENITAL MALFORMATION MALE | 2 |
| RASH | 2 |
| ANTIPHOSPHOLIPID ANTIBODIES POSITIVE | 2 |
| BLOOD ALBUMIN DECREASED | 1 |
| BLOOD BILIRUBIN INCREASED | 1 |
| CANDIDIASIS | 1 |
| CELLULITIS | 1 |
| Completed suicide | 1 |
| ARTHRALGIA | 1 |
| DRUG ADMINISTRATION ERROR | 1 |
| MENTAL STATUS CHANGES | 1 |
| ELECTROCARDIOGRAM QT PROLONGED | 1 |
| INTERNATIONAL NORMALISED RATIO INCREASED | 1 |
| JOINT EFFUSION | 1 |
| LEUKOENCEPHALOPATHY | 1 |
| Leukopenia | 1 |
| WHITE BLOOD CELL COUNT DECREASED | 1 |
| NEUTROPENIA | 1 |
| OFF LABEL USE | 1 |
| Oral infection | 1 |
| Pain | 1 |
| PERITONSILLAR ABSCESS | 1 |
| PLATELET COUNT DECREASED | 1 |
| PNEUMONIA | 1 |
| RENAL FAILURE ACUTE | 1 |
| SINUS TACHYCARDIA | 1 |
| Skin graft | 1 |
| Vasculitis | 1 |
| VENTRICULAR FIBRILLATION | 1 |
Toxicity information:
| Toxicity class: | 3 |
|---|---|
| Toxicity type: | hematological |
| LD50: | 138 mg/kg |
External links:
| ChEBML: | CHEMBL1454 |
|---|---|
| DrugBank: | DB00848 |