Withdrawn ID: | w43 |
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Canonical SMILES: | |
Standard InChI: | |
Standard InChIKey: | |
ATC class(es): | N05AL04 |
Molecular Formula: | C16H23BrN2O3 |
Molweight: | 371.269 |
Withdrawn due to drug safety reasons: | Yes |
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First approved: | 1991 |
First withdrawn: | 1993 |
Last withdrawn: | 1993 |
Reference: | https://www.ncbi.nlm.nih.gov/pubmed/1978484 |
Target UniProtKB ID | Activity in nm | Target Name | Target gene |
---|---|---|---|
P21917 | 3872 | D(4) dopamine receptor | DRD4_HUMAN |
Q16665 | 1995.3 | Hypoxia-inducible factor 1-alpha | HIF1A_HUMAN |
Toxicity class: | 4 |
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Toxicity type: | hematological |
LD50: | 325 mg/kg |
ChEBML: | CHEMBL22242 |
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DrugBank: | DB00409 |