Withdrawn ID: | w271 |
---|---|
Canonical SMILES: | |
Standard InChI: | |
Standard InChIKey: | |
ATC class(es): | L01BC04 |
Molecular Formula: | C11H16FN3O3 |
Molweight: | 257.261 |
Withdrawn due to drug safety reasons: | Yes |
---|---|
Reference: | https://www.ncbi.nlm.nih.gov/pubmed/19029469 |
Target UniProtKB ID | Activity in nm | Target Name | Target gene |
---|---|---|---|
P02545 | 100 | Prelamin-A/C | LMNA_HUMAN |
Q13510 | 20.7 | Acid ceramidase | ASAH1_HUMAN |
Q16637 | 199.5 | Survival motor neuron protein | SMN_HUMAN |
Toxicity class: | 3 |
---|---|
Toxicity type: | neurological |
LD50: | 268 mg/kg |
ChEBML: | CHEMBL460499 |
---|---|
DrugBank: | DB09010 |