Indoramin
General information:
| Withdrawn ID: | w264 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | C02CA02 |
| Molecular Formula: | C22H25N3O |
| Molweight: | 347.453 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First withdrawn: | 2011 |
| Reference: | https://www.ncbi.nlm.nih.gov/pubmed/24288637 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| P18089 | 528 | Alpha-2B adrenergic receptor | ADA2B_HUMAN |
| P18825 | 476 | Alpha-2C adrenergic receptor | ADA2C_HUMAN |
| P25100 | 110 | Alpha-1D adrenergic receptor | ADA1D_HUMAN |
Toxicity information:
| Toxicity class: | 4 |
|---|---|
| Toxicity type: | cardiovascular |
| LD50: | 410 mg/kg |
External links:
| ChEBML: | CHEMBL279516 |
|---|---|
| DrugBank: | DB08950 |