Adenosine Phosphate
General information:
| Withdrawn ID: | w253 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | V |
| Molecular Formula: | C10H14N5O7P |
| Molweight: | 347.221 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First withdrawn: | 1973 |
| Last withdrawn: | 1973 |
| Reference: | https://static-content.springer.com/esm/art%3A10.1186%2Fs12916-016-0553-2/MediaObjects/12916_2016_553_MOESM3_ESM.pdf |
Side-effects:
| Total reported cases (submitted by medical professionals) with Adenosine Phosphate as primary suspect: | 14 |
|---|
Reported final outcomes:
| Life-Threatening condition: | 1 |
|---|---|
| Hospitalization (initial or prolonged): | 1 |
Reported side-effects:
| Side-effect | Case number |
|---|---|
| Drug hypersensitivity | 9 |
| Arteriospasm coronary | 2 |
| Off label use | 2 |
| BRONCHOSPASM | 2 |
| Hypotension | 2 |
| Drug ineffective | 2 |
| Ventricular fibrillation | 2 |
| Electrocardiogram ST segment elevation | 1 |
| Abdominal pain upper | 1 |
| Anaphylactic reaction | 1 |
| Bradycardia | 1 |
| Drug interaction | 1 |
| Dyspnoea | 1 |
| Electrocardiogram PR prolongation | 1 |
| Flushing | 1 |
| Haemodynamic instability | 1 |
| Idiosyncratic drug reaction | 1 |
| Incorrect drug administration rate | 1 |
| RESPIRATORY ARREST | 1 |
| Respiratory failure | 1 |
| Stress cardiomyopathy | 1 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| P09467 | 140 | Fructose-1,6-bisphosphatase 1 | F16P1_HUMAN |
| P30542 | 500 | Adenosine receptor A1 | AA1R_HUMAN |
Toxicity information:
| Toxicity class: | 6 |
|---|---|
| Toxicity type: | cardiovascular |
| LD50: | 11250 mg/kg |
External links:
| ChEBML: | CHEMBL752 |
|---|---|
| DrugBank: | DB00131 |