Aminopyrine
General information:
| Withdrawn ID: | w215 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | N02BB03 |
| N02BB53 | |
| N02BB73 | |
| Molecular Formula: | C13H17N3O |
| Molweight: | 231.294 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First approved: | 1900 |
| First withdrawn: | 1970 |
| Last withdrawn: | 1970 |
| Reference: | https://www.ncbi.nlm.nih.gov/pubmed/25029569 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| P02545 | 63.1 | Prelamin-A/C | LMNA_HUMAN |
| P16473 | 7943.3 | Thyrotropin receptor | TSHR_HUMAN |
| Q6XQN6 | 1 | Nicotinate phosphoribosyltransferase | PNCB_HUMAN |
Toxicity information:
| Toxicity class: | 4 |
|---|---|
| Toxicity type: | renal |
| LD50: | 1070 mg/kg |
External links:
| ChEBML: | CHEMBL288470 |
|---|---|
| DrugBank: | DB01424 |