Telaprevir


w204



General information:


Withdrawn ID: w204
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es): J05AE11
Molecular Formula: C36H53N7O6
Molweight: 679.849



Withdrawal information:


Withdrawn due to drug safety reasons:Yes
First approved: 2011
First withdrawn: 2014
Last withdrawn: 2014
Reference: https://www.fda.gov/Drugs/DrugSafety/ucm332731.htm



Side-effects:

Total reported cases (submitted by medical professionals) with Telaprevir as primary suspect: 6574


Reported final outcomes:
Hospitalization (initial or prolonged): 2038
Death: 351
Life-Threatening condition: 128
Disability: 29
Intervention required to prevent permanent impairment/damage: 27
Congenital anomaly: 2


Reported side-effects:

Side-effect Case number
RASH1363
ANAEMIA1324
PRURITUS621
NAUSEA606
FATIGUE486
VOMITING377
PYREXIA329
THROMBOCYTOPENIA326
ASTHENIA320
DIARRHOEA313
NEUTROPENIA305
OFF LABEL USE293
RASH GENERALISED289
HAEMOGLOBIN DECREASED258
ANORECTAL DISCOMFORT250
DECREASED APPETITE248
DRUG INEFFECTIVE233
HEADACHE222
DEPRESSION214
DYSPNOEA198
DRUG INTOLERANCE190
WHITE BLOOD CELL COUNT DECREASED176
PLATELET COUNT DECREASED176
PANCYTOPENIA150
LEUKOPENIA150
INSOMNIA148
ANAL PRURITUS147
HAEMORRHOIDS146
ADVERSE EVENT140
Drug reaction with eosinophilia and systemic symptoms138
MALAISE137
DIZZINESS137
RASH PRURITIC132
WEIGHT DECREASED127
PNEUMONIA124
BLOOD CREATININE INCREASED120
INFLUENZA LIKE ILLNESS109
SEPSIS108
DYSGEUSIA106
OEDEMA PERIPHERAL103
DRUG ERUPTION102
PAIN100
PROCTALGIA98
DEATH97
DEHYDRATION95
CHILLS93
ASCITES90
RASH ERYTHEMATOUS89
RENAL FAILURE88
RENAL FAILURE ACUTE84
HYPERURICAEMIA82
DRY SKIN80
ERYTHEMA77
DRUG DOSE OMISSION77
RASH MACULO-PAPULAR76
DRUG RASH WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS75
URINARY TRACT INFECTION74
ANORECTAL DISORDER74
INFECTION73
ANXIETY72
SKIN REACTION71
RECTAL HAEMORRHAGE71
PRURITUS GENERALISED70
HEPATIC CIRRHOSIS70
COUGH70
DRUG INTERACTION68
TOXIC SKIN ERUPTION67
ARTHRALGIA67
RENAL IMPAIRMENT66
URTICARIA63
IRRITABILITY63
FACE OEDEMA63
MYALGIA62
NEUTROPHIL COUNT DECREASED60
PANCREATITIS58
HEPATITIS C58
SKIN EXFOLIATION57
ALOPECIA57
ABDOMINAL PAIN57
BLOOD URIC ACID INCREASED53
SWELLING FACE50
CHEST PAIN49
STEVENS-JOHNSON SYNDROME48
ERYTHEMA MULTIFORME48
RASH PAPULAR46
PANCREATITIS ACUTE46
LOSS OF CONSCIOUSNESS46
BLISTER46
SYNCOPE45
FEELING ABNORMAL45
CONSTIPATION45
ABDOMINAL PAIN UPPER45
DERMATITIS44
CELLULITIS44
STOMATITIS43
LIVER DISORDER43
LETHARGY43
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION43
HYPOTENSION43
OEDEMA41
DYSPEPSIA41
INCORRECT DOSE ADMINISTERED40
EPISTAXIS40
CONDITION AGGRAVATED40
VISION BLURRED39
VIRAL LOAD INCREASED39
HEPATIC FAILURE39
ECZEMA39
ABDOMINAL DISTENSION39
SEPTIC SHOCK38
DRY MOUTH37
CONFUSIONAL STATE37
SKIN LESION36
EOSINOPHILIA35
BLOOD BILIRUBIN INCREASED35
JAUNDICE34
GENERAL PHYSICAL HEALTH DETERIORATION34
WEIGHT INCREASED33
HYPOKALAEMIA33
TREMOR32
RETINOPATHY32
MENTAL DISORDER32
TREATMENT NONCOMPLIANCE31
MOUTH ULCERATION31
DEPRESSED MOOD31
SUICIDAL IDEATION30
STAPHYLOCOCCAL INFECTION29
MYOCARDIAL INFARCTION29
GASTROINTESTINAL DISORDER29
ALANINE AMINOTRANSFERASE INCREASED29
ABDOMINAL DISCOMFORT29
TRANSFUSION28
SKIN DISORDER28
OROPHARYNGEAL PAIN28
BACK PAIN28
HAEMATOCHEZIA27
PAIN IN EXTREMITY26
BLOOD POTASSIUM DECREASED26
VISUAL IMPAIRMENT25
RENAL DISORDER25
MULTI-ORGAN FAILURE25
ENCEPHALOPATHY25
ASPARTATE AMINOTRANSFERASE INCREASED25
MOOD SWINGS24
DYSPHAGIA24
RESPIRATORY FAILURE23
HEPATIC ENCEPHALOPATHY23
FALL23
TREATMENT FAILURE22
RED BLOOD CELL COUNT DECREASED22
RASH MACULAR22
PULMONARY EMBOLISM22
PSORIASIS22
MEMORY IMPAIRMENT22
HYPOAESTHESIA22
HAEMORRHOIDAL HAEMORRHAGE22
CONVULSION22
BLOOD GLUCOSE INCREASED22
SOMNOLENCE21
PALPITATIONS21
MUSCLE SPASMS21
Hepatocellular carcinoma21
GASTROINTESTINAL HAEMORRHAGE21
ACUTE RESPIRATORY DISTRESS SYNDROME21
Virologic failure20
Respiratory tract infection20
RASH PUSTULAR20
LOCAL SWELLING20
BLOOD UREA INCREASED20
BLOOD COUNT ABNORMAL20
UNEVALUABLE EVENT19
RESTLESSNESS19
PARAESTHESIA19
HYPERBILIRUBINAEMIA19
HOSPITALISATION19
DEEP VEIN THROMBOSIS19
SKIN BURNING SENSATION18
SINUSITIS18
RHABDOMYOLYSIS18
NO THERAPEUTIC RESPONSE18
EYE SWELLING18
AGGRESSION18
VASCULITIS17
PLEURAL EFFUSION17
ORAL CANDIDIASIS17
LYMPHADENOPATHY17
HYPERHIDROSIS17
HAEMOLYTIC ANAEMIA17
HAEMATEMESIS17
SWELLING16
SKIN ULCER16
NEUROPATHY PERIPHERAL16
JOINT SWELLING16
INFLUENZA16
HYPERTENSION16
HAEMORRHAGE16
DYSURIA16
DIABETES MELLITUS16
DERMATITIS EXFOLIATIVE16
BRONCHITIS16
BACTERAEMIA16
SLEEP DISORDER15
RASH VESICULAR15
OVERDOSE15
MUSCULOSKELETAL PAIN15
LIVER FUNCTION TEST ABNORMAL15
HYPONATRAEMIA15
HAEMATOCRIT DECREASED15
GINGIVAL BLEEDING15
GASTROOESOPHAGEAL REFLUX DISEASE15
GAIT DISTURBANCE15
FEELING COLD15
EOSINOPHIL COUNT INCREASED15
DYSPNOEA EXERTIONAL15
CEREBROVASCULAR ACCIDENT15
BURNING SENSATION15
BALANCE DISORDER15
TRANSAMINASES INCREASED14
SWOLLEN TONGUE14
STAPHYLOCOCCAL SEPSIS14
PERITONITIS BACTERIAL14
HYPOTHYROIDISM14
HYPERSENSITIVITY14
HEPATIC FUNCTION ABNORMAL14
HEART RATE INCREASED14
GLOMERULAR FILTRATION RATE DECREASED14
FLUID RETENTION14
FLATULENCE14
EYE PAIN14
APHAGIA14
ADVERSE DRUG REACTION14
TOXICITY TO VARIOUS AGENTS13
TACHYCARDIA13
PSYCHOTIC DISORDER13
ORAL PAIN13
MOOD ALTERED13
MIGRAINE13
LYMPHOPENIA13
LIP SWELLING13
EMOTIONAL DISORDER13
CHEST DISCOMFORT13
BONE MARROW FAILURE13
VERTIGO12
RETINAL HAEMORRHAGE12
PURPURA12
PHOTOPHOBIA12
NASOPHARYNGITIS12
GASTROENTERITIS12
EYE IRRITATION12
DISTURBANCE IN ATTENTION12
CARDIAC FAILURE12
ANGER12
VIRAL INFECTION11
UPPER RESPIRATORY TRACT INFECTION11
Skin toxicity11
RETCHING11
PROCTITIS11
MUSCULAR WEAKNESS11
MUCOSAL INFLAMMATION11
LUNG DISORDER11
INTERSTITIAL LUNG DISEASE11
INJECTION SITE ERYTHEMA11
HYPOCALCAEMIA11
GLOSSODYNIA11
GASTRITIS11
FEELING HOT11
DRY EYE11
BODY TEMPERATURE INCREASED11
VISUAL ACUITY REDUCED10
POLLAKIURIA10
PHOTOSENSITIVITY REACTION10
ORAL DISORDER10
INJECTION SITE RASH10
HERPES ZOSTER10
HALLUCINATION10
GENERALISED OEDEMA10
Gamma-glutamyltransferase increased10
FAECES DISCOLOURED10
Dermatitis allergic10
COLITIS10
CEREBRAL HAEMORRHAGE10
BRONCHOPNEUMONIA10
BLOOD THYROID STIMULATING HORMONE INCREASED10
BLOOD GLUCOSE DECREASED10
APLASTIC ANAEMIA10
APHTHOUS STOMATITIS10
Toxic epidermal necrolysis9
THROMBOSIS9
PULMONARY OEDEMA9
PRODUCTIVE COUGH9
PAROSMIA9
PALLOR9
LOWER RESPIRATORY TRACT INFECTION9
Investigation9
INCORRECT DRUG ADMINISTRATION DURATION9
HYPERSOMNIA9
Haematotoxicity9
FEBRILE NEUTROPENIA9
EATING DISORDER9
DYSPHONIA9
DEAFNESS9
CARDIAC ARREST9
AMNESIA9
ACCIDENTAL OVERDOSE9
ABASIA9
VAGINAL HAEMORRHAGE8
Pyelonephritis8
ORAL DISCOMFORT8
OPTIC NEURITIS8
NERVOUSNESS8
LIVER TRANSPLANT8
Lipase increased8
INJECTION SITE REACTION8
HAEMATURIA8
GOUT8
GENERALISED ERYTHEMA8
ESCHERICHIA SEPSIS8
EAR INFECTION8
DRUG ADMINISTRATION ERROR8
DISORIENTATION8
CRYING8
CONTUSION8
CHRONIC OBSTRUCTIVE PULMONARY DISEASE8
BLOOD TRIGLYCERIDES INCREASED8
BLOOD ALKALINE PHOSPHATASE INCREASED8
ANGIOEDEMA8
ANAL HAEMORRHAGE8
AGITATION8
ACUTE RESPIRATORY FAILURE8
Acute kidney injury8
WHEEZING7
UROSEPSIS7
THIRST7
SUICIDE ATTEMPT7
STAPHYLOCOCCAL BACTERAEMIA7
SKIN IRRITATION7
SKIN FISSURES7
Serum ferritin increased7
SCAB7
RETINAL EXUDATES7
RESPIRATORY DISORDER7
OESOPHAGEAL VARICES HAEMORRHAGE7
OCULAR HYPERAEMIA7
MENTAL IMPAIRMENT7
MELAENA7
LUNG INFECTION7
Laboratory test abnormal7
INTESTINAL OBSTRUCTION7
IMPETIGO7
Hypertriglyceridaemia7
HYPERKALAEMIA7
HYPERGLYCAEMIA7
HAEMOPTYSIS7
Furuncle7
EXFOLIATIVE RASH7
ERYSIPELAS7
ENDOCARDITIS7
DYSARTHRIA7
Discomfort7
DELIRIUM7
CYSTITIS7
CHOLECYSTITIS ACUTE7
BONE PAIN7
ATRIAL FIBRILLATION7
Arrhythmia7
Anal abscess7
AMMONIA INCREASED7
Wound6
VARICES OESOPHAGEAL6
URINE OUTPUT DECREASED6
UNDERDOSE6
TRANSIENT ISCHAEMIC ATTACK6
TONGUE DISORDER6
THYROID FUNCTION TEST ABNORMAL6
RETINAL DETACHMENT6
PULMONARY FIBROSIS6
PSYCHIATRIC SYMPTOM6
PRURIGO6
POOR QUALITY SLEEP6
Pneumonia aspiration6
PERIORBITAL OEDEMA6
PARANOIA6
PAIN OF SKIN6
Oral mucosal blistering6
ORAL FUNGAL INFECTION6
NIGHT SWEATS6
Nervous system disorder6
MENTAL STATUS CHANGES6
MEDICATION ERROR6
Liver transplant rejection6
Leukocytosis6
LACTIC ACIDOSIS6
Irritable bowel syndrome6
HOT FLUSH6
HEPATITIS CHOLESTATIC6
HEPATIC ENZYME INCREASED6
GLOSSITIS6
GINGIVITIS6
FUNGAL INFECTION6
EYELID OEDEMA6
EYE PRURITUS6
ESCHERICHIA URINARY TRACT INFECTION6
ERUCTATION6
ELECTROCARDIOGRAM QT PROLONGED6
DRUG HYPERSENSITIVITY6
Dermatitis bullous6
COMA6
Cataract6
CARDIAC DISORDER6
BLOOD SODIUM DECREASED6
BLOOD PRESSURE DECREASED6
Blood disorder6
BLOOD CREATINE PHOSPHOKINASE INCREASED6
Blood albumin decreased6
Blindness6
APPENDICITIS6
ANAPHYLACTIC REACTION6
ANAL FISSURE6
ALTERED STATE OF CONSCIOUSNESS6
ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS6
ABSCESS6
WHITE BLOOD CELL COUNT INCREASED5
UPPER GASTROINTESTINAL HAEMORRHAGE5
ULCER5
TUBERCULOSIS5
TINNITUS5
SYSTEMIC INFLAMMATORY RESPONSE SYNDROME5
SUDDEN DEATH5
SUBDURAL HAEMATOMA5
Stress5
SPEECH DISORDER5
SHOCK5
Sarcoidosis5
Rhinorrhoea5
RENAL FUNCTION TEST ABNORMAL5
PULMONARY HYPERTENSION5
PORTAL VEIN THROMBOSIS5
Pneumonia legionella5
Platelet count increased5
Peritonitis5
PERIPHERAL COLDNESS5
PAPULE5
PANNICULITIS5
PANIC ATTACK5
PAINFUL DEFAECATION5
NEPHROLITHIASIS5
MOBILITY DECREASED5
LOCALISED OEDEMA5
LISTLESS5
INTERNATIONAL NORMALISED RATIO INCREASED5
Immunosuppressant drug level increased5
Hypoglycaemia5
HYPOALBUMINAEMIA5
HYPOACUSIS5
HYPERTHYROIDISM5
Hypertensive crisis5
HYPERAESTHESIA5
Histiocytosis haematophagic5
HEPATORENAL SYNDROME5
Hepatitis5
Hepatic cancer5
GINGIVAL PAIN5
General physical condition abnormal5
GASTRIC DISORDER5
FLUSHING5
ELECTROLYTE IMBALANCE5
DIARRHOEA HAEMORRHAGIC5
Depressive symptom5
CREATININE RENAL CLEARANCE INCREASED5
COAGULOPATHY5
CARDIAC FAILURE CONGESTIVE5
C-REACTIVE PROTEIN INCREASED5
BLOOD POTASSIUM INCREASED5
Ataxia5
ASTHMA5
APHASIA5
Amylase increased5
AGEUSIA5
ACTIVITIES OF DAILY LIVING IMPAIRED5
ACNE5
ABNORMAL DREAMS5
VULVOVAGINAL PRURITUS4
VIITH NERVE PARALYSIS4
VENTRICULAR FIBRILLATION4
URINARY RETENTION4
TOOTH ABSCESS4
THROAT TIGHTNESS4
THINKING ABNORMAL4
Tearfulness4
SUPERINFECTION BACTERIAL4
SMALL INTESTINAL OBSTRUCTION4
Skin infection4
Skin discolouration4
SINUS HEADACHE4
SCIATICA4
RIB FRACTURE4
Retinal vein thrombosis4
RECTAL FISSURE4
PSYCHOMOTOR SKILLS IMPAIRED4
Presyncope4
PORPHYRIA NON-ACUTE4
POLYNEUROPATHY4
PLEURISY4
PHARYNGEAL OEDEMA4
Peripheral sensory neuropathy4
PERICARDIAL EFFUSION4
OSTEONECROSIS4
ORTHOSTATIC HYPOTENSION4
OROPHARYNGEAL BLISTERING4
ORAL HERPES4
Oesophageal candidiasis4
ODYNOPHAGIA4
NEUTROPHILIA4
NEPHROTIC SYNDROME4
Nephropathy toxic4
NECK PAIN4
MYOSITIS4
Muscle abscess4
MUCOUS MEMBRANE DISORDER4
MOUTH HAEMORRHAGE4
METABOLIC ACIDOSIS4
Malnutrition4
LYMPHOMA4
LYMPHADENOPATHY MEDIASTINAL4
LUNG INFILTRATION4
Lip blister4
LEUKOCYTOCLASTIC VASCULITIS4
INTESTINAL PERFORATION4
INTENTIONAL DRUG MISUSE4
Inguinal hernia4
HYPOVOLAEMIA4
HYPOPHAGIA4
HYPERTHERMIA4
HYPERAMYLASAEMIA4
HEPATOCELLULAR INJURY4
Hemiplegia4
HAEMATOMA4
GENITAL RASH4
GASTROINTESTINAL NECROSIS4
GASTRIC ULCER4
FUNGAL SKIN INFECTION4
FREQUENT BOWEL MOVEMENTS4
FLANK PAIN4
FAECES HARD4
EYE DISORDER4
EXCORIATION4
Drug level increased4
COMPLETED SUICIDE4
COLITIS ISCHAEMIC4
Clostridium difficile infection4
CIRCULATORY COLLAPSE4
CHROMATURIA4
CHOLESTASIS4
CHOLECYSTITIS4
CHEILITIS4
CD4 LYMPHOCYTES DECREASED4
CARDIOVASCULAR DISORDER4
Candida infection4
Cachexia4
BLOOD URINE PRESENT4
BLOOD PRESSURE INCREASED4
APPENDICECTOMY4
ANURIA4
ANGINA PECTORIS4
ANAPHYLACTIC SHOCK4
ADVERSE REACTION4
ADRENAL INSUFFICIENCY4
Acute myocardial infarction4
ACUTE HEPATIC FAILURE4
ABNORMAL FAECES4
ABNORMAL BEHAVIOUR4
Yellow skin3
XEROSIS3
Unresponsive to stimuli3
Type 1 diabetes mellitus3
Tuberculous pleurisy3
Transplant rejection3
TOOTHACHE3
Tooth disorder3
TONGUE DISCOLOURATION3
SYNOVIAL CYST3
SUNBURN3
Substance-induced psychotic disorder3
STAPHYLOCOCCAL SKIN INFECTION3
Soft tissue infection3
SENSORY DISTURBANCE3
SCROTAL SWELLING3
RHEUMATOID ARTHRITIS3
Restless legs syndrome3
RECTAL ABSCESS3
RASH MORBILLIFORM3
PRURITUS GENITAL3
Prostatic disorder3
POST PROCEDURAL HAEMORRHAGE3
PORTAL HYPERTENSION3
PNEUMONIA STREPTOCOCCAL3
Pneumonia staphylococcal3
Pneumonia bacterial3
Pigmentation disorder3
Peripheral swelling3
Otitis media3
OSTEOMYELITIS3
Oropharyngeal candidiasis3
Orchitis3
OEDEMA MOUTH3
NON-CARDIAC CHEST PAIN3
NEUTROPHIL COUNT INCREASED3
Neoplasm3
MUSCLE TWITCHING3
Muscle contracture3
MUCOSAL ULCERATION3
Menorrhagia3
LUNG NEOPLASM MALIGNANT3
LIVER INJURY3
Lip oedema3
LICHENOID KERATOSIS3
LARYNGITIS3
LACERATION3
Injection site swelling3
INJECTION SITE PRURITUS3
INJECTION SITE PAIN3
INCORRECT DRUG DOSAGE FORM ADMINISTERED3
Immunosuppression3
HYPOXIA3
HYPERCAPNIA3
HICCUPS3
Hepatotoxicity3
HEPATORENAL FAILURE3
Hepatic lesion3
HAEMORRHAGE INTRACRANIAL3
Haemoglobin abnormal3
GASTROINTESTINAL INFECTION3
FULL BLOOD COUNT DECREASED3
Full blood count abnormal3
Folliculitis3
Fibrosis3
Fear3
FAECES PALE3
FAECAL INCONTINENCE3
Eye haemorrhage3
ESCHERICHIA TEST POSITIVE3
ERYTHRODERMIC PSORIASIS3
ERECTILE DYSFUNCTION3
Empyema3
DRUG ABUSE3
Diverticulitis3
Disseminated tuberculosis3
DIPLOPIA3
Dialysis3
DIABETES MELLITUS INADEQUATE CONTROL3
Dermatosis3
DEPRESSED LEVEL OF CONSCIOUSNESS3
Dental caries3
CRYOGLOBULINAEMIA3
Conjunctivitis3
Compartment syndrome3
Clostridium difficile colitis3
CHOLELITHIASIS3
CHOLANGITIS3
CHOKING3
Brain abscess3
BLOOD POTASSIUM ABNORMAL3
BLOOD MAGNESIUM DECREASED3
Blood lactate dehydrogenase increased3
Blood creatinine abnormal3
BLOOD CHOLESTEROL INCREASED3
BLOOD CALCIUM DECREASED3
BICYTOPENIA3
BACTERIAL SEPSIS3
Bacterial infection3
Aspartate aminotransferase abnormal3
ARTHRITIS3
APLASIA3
ALPHA 1 FOETOPROTEIN INCREASED3
Alanine aminotransferase decreased3
AFFECT LABILITY3
ABDOMINAL PAIN LOWER3
WRIST FRACTURE2
Withdrawal syndrome2
WHITE BLOOD CELL COUNT ABNORMAL2
WHITE BLOOD CELL COUNT2
VULVOVAGINAL CANDIDIASIS2
VITREOUS FLOATERS2
Viraemia2
Vasculitic rash2
Vascular purpura2
URINE COLOUR ABNORMAL2
Urinary hesitation2
URINARY BLADDER HAEMORRHAGE2
Urate nephropathy2
Umbilical hernia2
TOOTH LOSS2
Tooth fracture2
Tongue dry2
TONGUE BLISTERING2
Thyroiditis2
THYROID DISORDER2
Thrombotic thrombocytopenic purpura2
Thrombotic microangiopathy2
THROMBOPHLEBITIS2
Throat irritation2
THERAPY CESSATION2
Therapeutic response unexpected2
THERAPEUTIC RESPONSE DECREASED2
Telangiectasia2
SURGERY2
Supraventricular tachycardia2
Superinfection2
Subcutaneous abscess2
SUBARACHNOID HAEMORRHAGE2
STREPTOCOCCAL SEPSIS2
Squamous cell carcinoma of skin2
SPLENOMEGALY2
Spinal column stenosis2
SKIN WARM2
Skin necrosis2
SKIN INJURY2
Skin hypertrophy2
Skin haemorrhage2
Sinus congestion2
Shock haemorrhagic2
Serum ferritin abnormal2
SENSATION OF FOREIGN BODY2
SELF-INJURIOUS IDEATION2
Seizure2
SEDATION2
ROAD TRAFFIC ACCIDENT2
Right ventricular failure2
RETINAL DISORDER2
RESPIRATORY RATE INCREASED2
Respiratory distress2
RESPIRATORY ACIDOSIS2
Renal tubular necrosis2
RENAL TUBULAR ACIDOSIS2
RENAL PAIN2
Renal injury2
Remission not achieved2
Refractory cytopenia with unilineage dysplasia2
Rectal ulcer2
RECTAL TENESMUS2
QUALITY OF LIFE DECREASED2
Pyelonephritis acute2
Pulmonary tuberculosis2
PULMONARY SEPSIS2
PULMONARY CONGESTION2
PSYCHOSOMATIC DISEASE2
PSYCHOMOTOR RETARDATION2
Psychomotor hyperactivity2
PSYCHIATRIC DECOMPENSATION2
PROSTATITIS ESCHERICHIA COLI2
Prostatitis2
Product quality issue2
Postmenopausal haemorrhage2
POIKILODERMA2
Pneumothorax2
PNEUMONITIS2
PNEUMOCOCCAL SEPSIS2
PLATELET DISORDER2
PHARYNGITIS STREPTOCOCCAL2
PHARYNGITIS2
PHARYNGEAL ULCERATION2
PERSONALITY CHANGE2
Perivascular dermatitis2
PERICARDITIS2
Penile pain2
Pathogen resistance2
PARAESTHESIA ORAL2
PANCREATIC DISORDER2
Pancreatic carcinoma2
Orthopnoea2
OROPHARYNGEAL PLAQUE2
Organ failure2
ORAL MUCOSAL ERYTHEMA2
Onychomadesis2
OLIGOMENORRHOEA2
OCULAR ICTERUS2
Nosocomial infection2
Normochromic normocytic anaemia2
NOCTURIA2
Neoplasm malignant2
Necrotising fasciitis staphylococcal2
NECK MASS2
Nasal ulcer2
NASAL DISCOMFORT2
Nasal congestion2
MUSCULOSKELETAL STIFFNESS2
MUSCULOSKELETAL DISCOMFORT2
MUSCULOSKELETAL CHEST PAIN2
MUSCLE TIGHTNESS2
MUSCLE STRAIN2
Muscle haemorrhage2
MULTI-ORGAN DISORDER2
Mucosal dryness2
Mucosal discolouration2
Mucocutaneous rash2
Mouth injury2
METABOLIC DISORDER2
METABOLIC ALKALOSIS2
MENINGITIS2
Malignant pleural effusion2
LYMPHOEDEMA2
Lymphocyte count decreased2
Lung adenocarcinoma2
LOWER RESPIRATORY TRACT INFECTION BACTERIAL2
Lower gastrointestinal haemorrhage2
LOCALISED INFECTION2
KLEBSIELLA SEPSIS2
Klebsiella infection2
KLEBSIELLA BACTERAEMIA2
KIDNEY INFECTION2
Iron deficiency anaemia2
INTESTINAL ISCHAEMIA2
Intervertebral disc disorder2
Injection site urticaria2
Inflammation2
INFECTIOUS PERITONITIS2
INCREASED UPPER AIRWAY SECRETION2
Immune thrombocytopenic purpura2
Immune system disorder2
ILEUS2
HYPOVENTILATION2
HYPOTHERMIA2
Hypersensitivity vasculitis2
Hyperpyrexia2
Hyperkeratosis2
Hyperchlorhydria2
Homicidal ideation2
Herpes simplex2
HEPATITIS C RNA INCREASED2
HEPATIC STEATOSIS2
HEPATIC PAIN2
HEPATIC NEOPLASM MALIGNANT RECURRENT2
HEPATIC NEOPLASM MALIGNANT2
HEPATIC FIBROSIS2
HEARING IMPAIRED2
Haemorrhoids thrombosed2
Haemolytic uraemic syndrome2
Haemoglobin increased2
Guillain-Barre syndrome2
Granulocyte count decreased2
GRAND MAL CONVULSION2
Glomerular filtration rate abnormal2
Gingival disorder2
Gingival blister2
Genitourinary tract infection2
GASTROINTESTINAL PAIN2
GASTROINTESTINAL MUCOSAL DISORDER2
Gastroenteritis viral2
Gastroenteritis norovirus2
GASTRITIS EROSIVE2
FUNCTIONAL GASTROINTESTINAL DISORDER2
FOOT FRACTURE2
FOOD INTOLERANCE2
Foetal exposure during pregnancy2
FEMORAL NECK FRACTURE2
FEELING OF BODY TEMPERATURE CHANGE2
FEELING DRUNK2
Feeding disorder2
FEBRILE INFECTION2
FAECALOMA2
EYELID PAIN2
Exercise tolerance decreased2
ESCHERICHIA BACTERAEMIA2
Erythema nodosum2
Epilepsy2
Eosinophil percentage increased2
Enterocolitis2
Enterococcal sepsis2
Enteritis infectious2
ENTERITIS2
Encephalitis2
EMOTIONAL DISTRESS2
Electrocardiogram abnormal2
EATING DISORDER SYMPTOM2
Dry throat2
Drug-induced liver injury2
DRUG WITHDRAWAL CONVULSIONS2
Drug resistance2
DRUG PRESCRIBING ERROR2
Drug effect incomplete2
Drug effect decreased2
Drug diversion2
DROOLING2
DIVERTICULUM INTESTINAL2
Disseminated intravascular coagulation2
Disease recurrence2
Diffuse large B-cell lymphoma2
Dermatitis psoriasiform2
DERMATITIS ATOPIC2
Depression suicidal2
DELUSION2
Decubitus ulcer2
CYST2
CROHN'S DISEASE2
Creatinine renal clearance decreased2
CORONARY ARTERY THROMBOSIS2
CORONARY ARTERY DISEASE2
Coordination abnormal2
COMPLICATIONS OF TRANSPLANTED LIVER2
COMMUNICATION DISORDER2
COLON CANCER2
COLD SWEAT2
Cognitive disorder2
CHAPPED LIPS2
CELLULITIS STAPHYLOCOCCAL2
CARDIOPULMONARY FAILURE2
CARDIO-RESPIRATORY ARREST2
Cardiac tamponade2
CANDIDIASIS2
Bursitis2
BRONCHOSPASM2
BRONCHOPULMONARY ASPERGILLOSIS2
BRADYPHRENIA2
BLOOD TEST ABNORMAL2
Blood iron increased2
BLOOD GLUCOSE ABNORMAL2
BLOOD CREATINE INCREASED2
Blood cortisol decreased2
BLINDNESS TRANSIENT2
Bilirubin conjugated increased2
BILIARY DYSKINESIA2
BACTERIAL PERICARDITIS2
Azotaemia2
Axillary mass2
Atrial septal defect2
ASTERIXIS2
Arthritis infective2
Arthritis bacterial2
Apathy2
ANGIOPATHY2
Anal ulcer2
Anaemia macrocytic2
Alanine aminotransferase abnormal2
Akathisia2
AGRANULOCYTOSIS2
Acute pulmonary oedema2
Acute psychosis2
Acute prerenal failure2
ABSCESS LIMB2
Abdominal abscess2
Zygomycosis1
WRONG DRUG ADMINISTERED1
Wound secretion1
WOUND HAEMORRHAGE1
Wernicke's encephalopathy1
Weight fluctuation1
VULVOVAGINAL MYCOTIC INFECTION1
VOMITING PROJECTILE1
VITAMIN D DECREASED1
Viral upper respiratory tract infection1
Viral titre increased1
Viral load1
VICTIM OF HOMICIDE1
Victim of abuse1
VENTRICULAR FAILURE1
Vein disorder1
VASCULAR INJURY1
Varicose vein ruptured1
Varicose vein1
Varicella1
Vaginal disorder1
URTICARIA PAPULAR1
Urine flow decreased1
Urine analysis abnormal1
URINARY TRACT INFECTION ENTEROCOCCAL1
Urinary tract infection bacterial1
Urinary tract disorder1
URINARY INCONTINENCE1
URETERAL STENT INSERTION1
Umbilical hernia repair1
Umbilical haemorrhage1
ULCER HAEMORRHAGE1
TYPE III IMMUNE COMPLEX MEDIATED REACTION1
TYMPANIC MEMBRANE PERFORATION1
Tumour haemorrhage1
Tubulointerstitial nephritis1
TROPONIN INCREASED1
Tri-iodothyronine decreased1
Transplant1
Transferrin saturation increased1
Toxic encephalopathy1
Tooth repair1
Tooth infection1
TONSILLITIS1
Tongue ulceration1
Tongue pigmentation1
Tongue oedema1
Tinea pedis1
Tinea infection1
Thyroxine decreased1
Thirst decreased1
Thermal burn1
Therapy responder1
Therapeutic product ineffective1
TESTICULAR DISORDER1
Tenderness1
Temporal arteritis1
Temperature intolerance1
Sweat gland disorder1
SUDDEN CARDIAC DEATH1
SUBSTANCE USE1
Substance abuse1
Subcutaneous haematoma1
SUBCUTANEOUS EMPHYSEMA1
Strongyloidiasis1
Stridor1
Strangulated hernia1
Stoma site haemorrhage1
STENT PLACEMENT1
Status epilepticus1
Staphylococcal abscess1
SPLENECTOMY1
Spinal fracture1
Spastic paraplegia1
SOPOR1
Solar dermatitis1
Soft tissue disorder1
Social avoidant behaviour1
Sneezing1
Sluggishness1
Skull fracture1
Skin tightness1
SKIN SENSITISATION1
SKIN PLAQUE1
Skin odour abnormal1
Skin depigmentation1
Skeletal injury1
SJOGREN'S SYNDROME1
SINUS TACHYCARDIA1
SINUS ARREST1
SHUNT INFECTION1
Sensory loss1
Sense of oppression1
SELF INJURIOUS BEHAVIOUR1
SEGMENTED HYALINISING VASCULITIS1
Seborrhoeic dermatitis1
Screaming1
SCRATCH1
SCOTOMA1
Scleritis1
Scar pain1
Scar1
SALIVARY HYPERSECRETION1
Salivary gland calculus1
Saliva altered1
RHINALGIA1
Rheumatoid factor increased1
Retroperitoneal haemorrhage1
Retinoschisis1
Retinitis1
RETINAL VEIN OCCLUSION1
Retinal tear1
RETINAL ARTERY OCCLUSION1
Respiratory tract congestion1
RESPIRATORY ARREST1
RESPIRATORY ALKALOSIS1
RESPIRATION ABNORMAL1
Renal tubular disorder1
RENAL FAILURE CHRONIC1
Renal cancer1
Renal abscess1
Rehabilitation therapy1
Red cell distribution width increased1
Red blood cell sedimentation rate increased1
RED BLOOD CELL COUNT ABNORMAL1
Rectal spasm1
RECTAL DISCHARGE1
Rales1
Purulence1
Puncture site erythema1
PULSELESS ELECTRICAL ACTIVITY1
PULMONARY VASCULITIS1
Pulmonary mass1
PULMONARY HAEMORRHAGE1
Pulmonary arterial pressure increased1
PSORIATIC ARTHROPATHY1
Prothrombin time shortened1
Proteus infection1
Protein total decreased1
Prostate cancer1
Product taste abnormal1
Product odour abnormal1
PROCEDURAL SITE REACTION1
PROCEDURAL PAIN1
Prerenal failure1
Pregnancy1
Potentiating drug interaction1
Postoperative abscess1
POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME1
POST THROMBOTIC SYNDROME1
POST PROCEDURAL COMPLICATION1
Portal hypertensive gastropathy1
POOR QUALITY DRUG ADMINISTERED1
Polyuria1
POLYP COLORECTAL1
PNEUMONIA PRIMARY ATYPICAL1
Pneumonia klebsiella1
Pneumonia escherichia1
Pneumocystis jirovecii infection1
PNEUMOCOCCAL INFECTION1
PNEUMOCOCCAL BACTERAEMIA1
Platelet production decreased1
Pityriasis rubra pilaris1
Pituitary-dependent Cushing's syndrome1
Pica1
Phlebitis superficial1
Pharyngitis bacterial1
Pharyngeal cancer1
Petit mal epilepsy1
Peritonsillar abscess1
Periproctitis1
Peripheral arterial occlusive disease1
Periorbital contusion1
Periodontitis1
Pericarditis constrictive1
Perianal erythema1
Penile size reduced1
Penile burning sensation1
Pemphigus1
Peau d'orange1
Patent ductus arteriosus1
PARTNER STRESS1
Partial seizures1
Parotitis1
Paronychia1
Parkinson's disease1
Paralysis1
PANIC REACTION1
Panic disorder1
Pancreatic insufficiency1
PANCREATIC FISTULA1
PANCREAS INFECTION1
Palmar-plantar erythrodysaesthesia syndrome1
Packed red blood cell transfusion1
Oxygen saturation decreased1
Ovarian cyst1
Ovarian cancer stage IV1
Osteoporotic fracture1
Oropharyngeal discomfort1
Organising pneumonia1
Oral pruritus1
Oral mucosal exfoliation1
Oral mucosal eruption1
Optic nerve sheath haemorrhage1
Optic nerve disorder1
OPTIC ISCHAEMIC NEUROPATHY1
Ophthalmic herpes simplex1
Onychomycosis1
OLIGURIA1
OESOPHAGITIS ULCERATIVE1
Oesophagitis bacterial1
Oesophagitis1
Oesophageal haemorrhage1
OCULAR ISCHAEMIC SYNDROME1
Obstruction gastric1
Nonspecific reaction1
Nodule1
No adverse event1
NIGHTMARE1
NEUTROPHIL PERCENTAGE DECREASED1
Neutropenic sepsis1
Neurosis1
Neuropsychiatric syndrome1
NEURODERMATITIS1
NEURITIS1
Neuralgia1
Neglect of personal appearance1
Necrotising fasciitis streptococcal1
Necrotising fasciitis1
Nasal oedema1
Nasal obstruction1
Nasal mucosal disorder1
Nasal dryness1
NAIL DISORDER1
Myoglobin urine present1
Myocarditis1
Myocardial ischaemia1
Myocardial fibrosis1
Myelitis1
Mycobacterium abscessus infection1
Myasthenia gravis crisis1
Musculoskeletal disorder1
Muscle enzyme increased1
MUSCLE ATROPHY1
MULTIPLE DRUG OVERDOSE1
Mucosal excoriation1
Mucosal erosion1
MOVEMENT DISORDER1
Mononeuropathy multiplex1
MITOCHONDRIAL TOXICITY1
MIOSIS1
Miliaria1
MICTURITION URGENCY1
Metastatic neoplasm1
Metastases to liver1
Metabolic encephalopathy1
Meningitis staphylococcal1
Meningitis aseptic1
Melanocytic naevus1
Maternal exposure during pregnancy1
Mastocytosis1
Mastication disorder1
MASS1
MANIA1
Mallory-Weiss syndrome1
MALIGNANT MELANOMA1
MALE ORGASMIC DISORDER1
Madarosis1
Lymphocytosis1
LYMPHOCYTE MORPHOLOGY ABNORMAL1
Lymphocyte count increased1
Lymphatic disorder1
Lymphangitis1
Lymph node tuberculosis1
Lymph node abscess1
Lupus-like syndrome1
Lung adenocarcinoma stage IV1
Lung abscess1
Lumbar vertebral fracture1
Loss of libido1
Loose tooth1
Living in residential institution1
Liver sarcoidosis1
Liver abscess1
Livedo reticularis1
LISTERIOSIS1
Listeria sepsis1
LIPASE ABNORMAL1
Lip squamous cell carcinoma1
LIP PAIN1
Lip erosion1
Lip dry1
Ligament rupture1
Lichenification1
Lichen planus1
LIBIDO INCREASED1
LIBIDO DECREASED1
Leukoencephalopathy1
Leukaemia1
Laryngeal cancer1
Large intestine polyp1
LARGE INTESTINAL ULCER1
Large intestinal obstruction1
Language disorder1
Lacrimation increased1
Laboratory test interference1
Klebsiella test positive1
KETOACIDOSIS1
Joint stiffness1
Jejunal ulcer perforation1
Ischaemic stroke1
Ischaemic hepatitis1
Ischaemia1
Intussusception1
INTRACRANIAL PRESSURE INCREASED1
INTRACRANIAL ANEURYSM1
Intra-abdominal haemorrhage1
INTESTINAL INFARCTION1
Intestinal gangrene1
Intervertebral discitis1
International normalised ratio fluctuation1
Intentional self-injury1
Intentional product misuse1
Intentional overdose1
Injury1
INJECTION SITE THROMBOSIS1
Injection site necrosis1
INJECTION SITE INFLAMMATION1
INJECTION SITE INDURATION1
Injection site haematoma1
INJECTION SITE CELLULITIS1
Injection site bruising1
Initial insomnia1
Infusion related reaction1
Infertility1
Infective spondylitis1
Infective glossitis1
Infective exacerbation of chronic obstructive airways disease1
Infectious thyroiditis1
Increased tendency to bruise1
Increased appetite1
Incontinence1
INCOHERENT1
Incisional hernia1
INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION1
Inadequate diet1
IMPULSIVE BEHAVIOUR1
IMPATIENCE1
IMPAIRED WORK ABILITY1
IMPAIRED HEALING1
Impaired driving ability1
Immunosuppressant drug level decreased1
IIIRD NERVE PARALYSIS1
IgA nephropathy1
Ichthyosis1
Hypoxic-ischaemic encephalopathy1
Hypovolaemic shock1
HYPOTONIA1
Hypoproteinaemia1
Hypomagnesaemia1
HYPOGEUSIA1
Hypertrichosis1
Hyperphosphataemia1
HYPEROSMOLAR STATE1
Hypernatraemia1
Hyperlipidaemia1
Hyperlipasaemia1
Hypereosinophilic syndrome1
HYPERCREATININAEMIA1
Hypercholesterolaemia1
HYPERCHLORAEMIA1
HYPERCATABOLISM1
Hyperammonaemia1
HUNGER1
Hormone level abnormal1
Hordeolum1
Hidradenitis1
HERNIA PAIN1
Hepatopulmonary syndrome1
Hepatomegaly1
HEPATITIS FULMINANT1
Hepatic neoplasm1
Hepatic necrosis1
Hepatic infiltration eosinophilic1
Hepatic artery thrombosis1
Hepatic amoebiasis1
HEMIPARESIS1
HELICOBACTER TEST POSITIVE1
Helicobacter gastritis1
HEAT STROKE1
HEART RATE DECREASED1
HEAD INJURY1
HALLUCINATIONS, MIXED1
Hair texture abnormal1
HAIR GROWTH ABNORMAL1
HAIR COLOUR CHANGES1
HAEMORRHOID INFECTION1
Haemorrhagic anaemia1
Haemophilic arthropathy1
Haemolysis1
Haematospermia1
Haematology test abnormal1
H1N1 influenza1
Gynaecomastia1
GROWTH OF EYELASHES1
Groin abscess1
GRAVITATIONAL OEDEMA1
Granuloma1
Goitre1
Glycosylated haemoglobin increased1
GLUCOSE TOLERANCE IMPAIRED1
Glomerulonephropathy1
Glomerulonephritis proliferative1
Glomerulonephritis acute1
Gingival hyperplasia1
Genital herpes1
GENITAL HAEMORRHAGE1
GENITAL BURNING SENSATION1
GASTROINTESTINAL ULCER HAEMORRHAGE1
Gastrointestinal motility disorder1
Gastrointestinal ischaemia1
Gastrointestinal inflammation1
Gastrointestinal fungal infection1
Gastrointestinal erosion1
GASTROENTERITIS STAPHYLOCOCCAL1
Gastroenteritis rotavirus1
Gastroenteritis clostridial1
Gastroenteritis bacterial1
Gastroduodenal haemorrhage1
Gastritis haemorrhagic1
GASTRIC VARICES HAEMORRHAGE1
Gastric ulcer haemorrhage1
Gastric cancer1
GAS POISONING1
GANGRENE1
Gamma-glutamyltransferase abnormal1
GALLBLADDER DISORDER1
Frustration1
FORMICATION1
FOREIGN BODY SENSATION IN EYES1
FOOD CRAVING1
Food allergy1
Follicle centre lymphoma, follicular grade I, II, III recurrent1
FLUID OVERLOAD1
FLUID INTAKE REDUCED1
Femur fracture1
FEELING OF DESPAIR1
FEAR OF EATING1
Fat intolerance1
Fasciitis1
Failure to thrive1
Faeces soft1
FACIAL PAIN1
FACIAL ASYMMETRY1
EYELIDS PRURITUS1
Eyelid cyst1
EYE MOVEMENT DISORDER1
EYE INFLAMMATION1
Eye infection bacterial1
Eye discharge1
Extrasystoles1
Extrapyramidal disorder1
EXTRAOCULAR MUSCLE DISORDER1
Exposure via father1
Exposure during pregnancy1
Expired product administered1
Expired drug administered1
Escherichia infection1
Erythrasma1
ERYTHEMA OF EYELID1
EROSIVE OESOPHAGITIS1
Erosive duodenitis1
Epidermolysis1
EPIDERMAL NECROSIS1
Eosinophilic pustular folliculitis1
Eosinophilic cellulitis1
EOSINOPHIL COUNT ABNORMAL1
ENTEROBACTER SEPSIS1
Endodontic procedure1
Endocrine disorder1
Emphysema1
Embolism1
Elevated mood1
ELECTROCARDIOGRAM CHANGE1
Ejection fraction decreased1
EJACULATION DISORDER1
Eczema nummular1
Eczema infected1
Eczema eyelids1
Eczema asteatotic1
Ecthyma1
ECHOCARDIOGRAM ABNORMAL1
Echinococciasis1
EAR DISCOMFORT1
DYSSTASIA1
Dysphemia1
Dyshidrotic eczema1
DYSGRAPHIA1
Dysfunctional uterine bleeding1
DRUG WITHDRAWAL SYNDROME1
DRUG LEVEL BELOW THERAPEUTIC1
DRUG EFFECT INCREASED1
DRUG DISPENSING ERROR1
Drug detoxification1
DRUG CLEARANCE DECREASED1
Diverticulum intestinal haemorrhagic1
DIVERTICULUM1
Dissociation1
Disease progression1
Diastasis recti abdominis1
Diarrhoea infectious1
Diaphragmatic paralysis1
Diabetic hyperglycaemic coma1
Device related infection1
Dermatitis infected1
DERMATITIS CONTACT1
Dermatitis acneiform1
DERMAL CYST1
Dermabrasion1
Dementia1
Delusional disorder, persecutory type1
Decreased interest1
DARK CIRCLES UNDER EYES1
Dandruff1
Dacryocystitis1
Cytomegalovirus viraemia1
Cytomegalovirus test positive1
Cytomegalovirus infection1
Cytomegalovirus enteritis1
CYTOLYTIC HEPATITIS1
CYSTITIS NONINFECTIVE1
Cystitis bacterial1
CYSTIC FIBROSIS PANCREATIC1
Cyanosis1
Cutaneous vasculitis1
Cutaneous tuberculosis1
Cutaneous sarcoidosis1
Cushingoid1
Cushing's syndrome1
Creatinine renal clearance abnormal1
Craniocerebral injury1
Cranial nerve paralysis1
Coronary artery occlusion1
CORNEAL OPACITY1
Conversion disorder1
CONTRAINDICATION TO MEDICAL TREATMENT1
CONJUNCTIVITIS INFECTIVE1
CONJUNCTIVITIS ALLERGIC1
Congestive cardiomyopathy1
Congenital cystic lung1
Coma hepatic1
Colony stimulating factor therapy1
COLONIC POLYP1
COLON OPERATION1
Colon adenoma1
Coeliac disease1
CLUSTER HEADACHE1
CLOSTRIDIAL INFECTION1
CHRONIC HEPATIC FAILURE1
Choreoathetosis1
CHOLECYSTECTOMY1
Cholangiocarcinoma1
Chloroma1
CHEILOSIS1
Cervix inflammation1
Cerumen impaction1
Ceruloplasmin increased1
CEREBROVASCULAR ARTERIOVENOUS MALFORMATION1
CEREBRAL INFARCTION1
Cerebral haematoma1
Cerebellar syndrome1
CELLULITIS ORBITAL1
Cellulitis gangrenous1
CATATONIA1
Cardiovascular insufficiency1
Cardiotoxicity1
Cardiomyopathy1
Cardiomegaly1
Cardiac hypertrophy1
Cardiac enzymes increased1
Carbuncle1
Carbon dioxide decreased1
Candida test positive1
Candida sepsis1
C-reactive protein decreased1
Bursitis infective1
BURNS THIRD DEGREE1
BURNING SENSATION MUCOSAL1
Bundle branch block left1
Bullous impetigo1
Bronchopulmonary disease1
Bronchopneumopathy1
Bronchiolitis1
Bronchial obstruction1
Breech presentation1
BREAST TENDERNESS1
Breast swelling1
Breast enlargement1
Breast cancer1
Brain scan abnormal1
Brain neoplasm malignant1
BRAIN NATRIURETIC PEPTIDE INCREASED1
Brain injury1
Bradycardia1
Bowel movement irregularity1
Borderline personality disorder1
Bone marrow transplant1
BONE MARROW DISORDER1
BONE INFARCTION1
BLOOD URIC ACID1
BLOOD SODIUM ABNORMAL1
BLOOD PRODUCT TRANSFUSION DEPENDENT1
Blood pressure fluctuation1
Blood pressure diastolic decreased1
Blood phosphorus decreased1
BLOOD LACTIC ACID INCREASED1
Blood iron decreased1
Blood immunoglobulin E increased1
Blood glucose fluctuation1
Blood creatine decreased1
Blood corticotrophin decreased1
BLOOD BLISTER1
Blood beta-D-glucan increased1
Blood alcohol increased1
Blood albumin increased1
Blood albumin abnormal1
Blindness unilateral1
Bleeding varicose vein1
Bladder cancer1
BIPOLAR DISORDER1
Biliary sepsis1
BILIARY COLIC1
Basal cell carcinoma1
BACTERIAL TRANSLOCATION1
Bacterial test positive1
Bacterascites1
Azoospermia1
Axonal neuropathy1
Autoimmune thyroiditis1
Autoimmune haemolytic anaemia1
AURICULAR SWELLING1
Atypical pneumonia1
Atypical mycobacterial infection1
Atrioventricular block complete1
Atrial tachycardia1
Atrial flutter1
ASTHMATIC CRISIS1
Asthenopia1
Asteatosis1
ASPIRATION1
Aspergillus test positive1
Aspergillosis1
ARTHROPOD STING1
Arthropod bite1
ARTHROPATHY1
ARTERIOVENOUS MALFORMATION1
Arteriovenous fistula thrombosis1
ARTERIOVENOUS FISTULA1
ARTERIOSCLEROSIS1
ARTERIAL OCCLUSIVE DISEASE1
ARACHNOIDITIS1
Aquagenic pruritus1
APPLICATION SITE EROSION1
APPETITE DISORDER1
Aplasia pure red cell1
Aphthous ulcer1
Aortitis1
Aortic dissection1
Aortic aneurysm1
Antithrombin III increased1
Antinuclear antibody increased1
Anti-thyroid antibody1
ANOSMIA1
ANKLE FRACTURE1
ANGIOMYOLIPOMA1
Angina unstable1
ANAL STENOSIS1
Anal injury1
ANAL INFLAMMATION1
Anal fistula1
ANAL EROSION1
Anal cancer1
ANAEMIA MEGALOBLASTIC1
Amyotrophy1
Amyotrophic lateral sclerosis1
ALVEOLITIS1
Allergic transfusion reaction1
Alcoholism1
ADMINISTRATION SITE RASH1
Administration site pain1
Adenocarcinoma1
Acute myeloid leukaemia1
Acute febrile neutrophilic dermatosis1
Acute coronary syndrome1
ACROCHORDON1
Acinetobacter infection1
ACIDOSIS1
Acarodermatitis1
ABSCESS STERILE1
Abscess jaw1
Abnormal weight gain1
Abnormal sensation in eye1
Abnormal loss of weight1
Abdominal wall abscess1
Abdominal sepsis1
ABDOMINAL MASS1





Filtered ChEMBL targets:

Target UniProtKB ID Activity in nm Target Name Target gene
O60911 1350 Cathepsin L2 CATL2_HUMAN
P00734 1000 Prothrombin THRB_HUMAN
P00747 8700 Plasminogen PLMN_HUMAN
P07711 3500 Procathepsin L CATL1_HUMAN
P07858 2300 Cathepsin B CATB_HUMAN
P08246 680 Neutrophil elastase ELNE_HUMAN
P23946 26 Chymase CMA1_HUMAN
P25774 300 Cathepsin S CATS_HUMAN
P43235 630 Cathepsin K CATK_HUMAN
Q9UNI1 30 Chymotrypsin-like elastase family member 1 CELA1_HUMAN



Toxicity information:

Toxicity type: unknown



External links:

ChEBML: CHEMBL231813
DrugBank: DB05521