Rosiglitazone

General information:

Withdrawn ID:	w166
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es):	A10BG02
Molecular Formula:	C18H19N3O3S
Molweight:	357.427

Withdrawal information:

Withdrawn due to drug safety reasons:	Yes
First approved:	1999
First death:	2007
First withdrawn:	2010
Last withdrawn:	2010
Reference:	https://www.ncbi.nlm.nih.gov/pubmed/25323655

Side-effects:

Total reported cases (submitted by medical professionals) with Rosiglitazone as primary suspect:	45941

Reported final outcomes:

Hospitalization (initial or prolonged):	38339
Death:	7220
Disability:	389
Life-Threatening condition:	203
Intervention required to prevent permanent impairment/damage:	39
Congenital anomaly:	10

Reported side-effects:

Side-effect	Case number
MYOCARDIAL INFARCTION	18926
CARDIAC FAILURE CONGESTIVE	15882
CEREBROVASCULAR ACCIDENT	7964
CORONARY ARTERY DISEASE	7830
ACUTE MYOCARDIAL INFARCTION	3062
CARDIAC DISORDER	2512
DEATH	1905
ATRIAL FIBRILLATION	1679
CHEST PAIN	1656
CORONARY ARTERY BYPASS	1587
MYOCARDIAL ISCHAEMIA	1570
CARDIOVASCULAR DISORDER	1491
TRANSIENT ISCHAEMIC ATTACK	1407
ANGINA UNSTABLE	1192
CARDIAC ARREST	1189
CORONARY ARTERIAL STENT INSERTION	1184
HYPERTENSION	1133
ANGINA PECTORIS	1049
DYSPNOEA	949
ISCHAEMIC CARDIOMYOPATHY	890
CARDIO-RESPIRATORY ARREST	886
ACUTE CORONARY SYNDROME	787
CARDIOMYOPATHY	778
ARTERIOSCLEROSIS	744
CARDIAC FAILURE	701
STENT PLACEMENT	690
ARTERIOSCLEROSIS CORONARY ARTERY	637
ARRHYTHMIA	590
PAIN	549
RENAL FAILURE	532
HEART INJURY	496
PLEURAL EFFUSION	493
INJURY	474
PULMONARY OEDEMA	461
WEIGHT INCREASED	451
VASCULAR GRAFT	414
OEDEMA PERIPHERAL	388
OEDEMA	356
CORONARY ARTERY OCCLUSION	341
FATIGUE	305
SUDDEN CARDIAC DEATH	301
CEREBRAL INFARCTION	293
DEPRESSION	283
VENTRICULAR TACHYCARDIA	274
FLUID RETENTION	274
ASTHENIA	266
CONGESTIVE CARDIOMYOPATHY	258
ANAEMIA	258
RESPIRATORY FAILURE	249
CARDIOGENIC SHOCK	235
CARDIOMEGALY	234
MITRAL VALVE INCOMPETENCE	233
HYPERLIPIDAEMIA	228
ISCHAEMIC STROKE	223
DIZZINESS	222
PULMONARY HYPERTENSION	210
AMNESIA	209
ANXIETY	206
SUPRAVENTRICULAR TACHYCARDIA	203
PERICARDIAL EFFUSION	200
HEART RATE IRREGULAR	200
VENTRICULAR FIBRILLATION	196
CATHETERISATION CARDIAC	193
MACULAR OEDEMA	191
PALPITATIONS	188
BLINDNESS	188
THROMBOSIS	181
CARDIAC PACEMAKER INSERTION	178
ISCHAEMIA	175
RENAL FAILURE ACUTE	174
CONDITION AGGRAVATED	168
ATRIAL FLUTTER	167
PNEUMONIA	165
CHRONIC OBSTRUCTIVE PULMONARY DISEASE	165
CARDIAC OPERATION	160
HYPERTENSIVE HEART DISEASE	154
AORTIC STENOSIS	152
PULMONARY EMBOLISM	150
PAIN IN EXTREMITY	149
ATRIOVENTRICULAR BLOCK COMPLETE	147
HEADACHE	146
IMPLANTABLE DEFIBRILLATOR INSERTION	145
ARTERIAL OCCLUSIVE DISEASE	145
VISION BLURRED	144
CAROTID ARTERY STENOSIS	143
SYNCOPE	141
LACUNAR INFARCTION	139
ADVERSE EVENT	137
PERIPHERAL VASCULAR DISORDER	135
CORONARY ARTERY STENOSIS	128
ATRIOVENTRICULAR BLOCK	128
CHEST DISCOMFORT	127
GAIT DISTURBANCE	123
NAUSEA	121
HYPOAESTHESIA	121
SWELLING	119
DIABETES MELLITUS	116
LEFT VENTRICULAR DYSFUNCTION	115
HEMIPARESIS	115
TRICUSPID VALVE INCOMPETENCE	114
RENAL FAILURE CHRONIC	113
CARDIAC VALVE DISEASE	112
BRADYCARDIA	112
FALL	111
SILENT MYOCARDIAL INFARCTION	108
HYPOGLYCAEMIA	108
HEPATIC FAILURE	108
CONVULSION	104
CEREBROVASCULAR DISORDER	104
VISUAL ACUITY REDUCED	101
SICK SINUS SYNDROME	101
CEREBRAL HAEMORRHAGE	100
SEPSIS	95
RENAL DISORDER	94
HEART RATE INCREASED	91
VISUAL IMPAIRMENT	90
INTRACARDIAC THROMBUS	89
LOSS OF CONSCIOUSNESS	86
LUNG DISORDER	85
ANGIOPLASTY	85
DIASTOLIC DYSFUNCTION	84
LIVER INJURY	81
FRACTURE	80
CARDIAC DEATH	80
HYPOTENSION	78
TACHYCARDIA	77
HYPOXIC-ISCHAEMIC ENCEPHALOPATHY	77
FLUID OVERLOAD	77
LEFT VENTRICULAR HYPERTROPHY	76
MALAISE	75
DIABETES MELLITUS INADEQUATE CONTROL	74
CORONARY ANGIOPLASTY	74
CARDIOPULMONARY FAILURE	74
ACUTE RESPIRATORY FAILURE	73
DYSPNOEA EXERTIONAL	71
ELECTROCARDIOGRAM ABNORMAL	70
ILL-DEFINED DISORDER	69
BLOOD CHOLESTEROL INCREASED	69
ACUTE PULMONARY OEDEMA	69
VOMITING	67
WEIGHT DECREASED	66
HEMIPLEGIA	65
EMOTIONAL DISTRESS	65
CARDIAC ASSISTANCE DEVICE USER	65
BLOOD GLUCOSE INCREASED	65
DEEP VEIN THROMBOSIS	64
COUGH	63
HAEMORRHAGIC STROKE	62
BUNDLE BRANCH BLOCK LEFT	62
BALANCE DISORDER	61
JOINT SWELLING	59
HEPATIC CIRRHOSIS	57
EYE DISORDER	57
EJECTION FRACTION DECREASED	57
INSOMNIA	56
CARDIAC MURMUR	55
BUNDLE BRANCH BLOCK RIGHT	55
AORTIC VALVE INCOMPETENCE	55
SLEEP APNOEA SYNDROME	54
CAROTID ARTERY DISEASE	54
BRAIN INJURY	54
ATRIOVENTRICULAR BLOCK FIRST DEGREE	54
MUSCULAR WEAKNESS	52
HAEMORRHAGE INTRACRANIAL	52
PARALYSIS	51
MULTI-ORGAN FAILURE	51
BRAIN STEM INFARCTION	51
RENAL INJURY	50
COR PULMONALE	50
VENTRICULAR EXTRASYSTOLES	49
DISABILITY	49
DIARRHOEA	49
RIGHT VENTRICULAR FAILURE	48
RESPIRATORY ARREST	48
MUSCLE SPASMS	48
HYPERTENSIVE CRISIS	48
ABDOMINAL PAIN	48
ABASIA	48
SPEECH DISORDER	47
Sinus node dysfunction	47
NEPHROPATHY	47
LIVER DISORDER	47
COMA	47
PARAESTHESIA	46
CARDIAC FAILURE CHRONIC	46
ATRIOVENTRICULAR BLOCK SECOND DEGREE	46
AORTIC VALVE STENOSIS	46
THALAMIC INFARCTION	45
RENAL IMPAIRMENT	45
JAUNDICE	45
CEREBELLAR INFARCTION	44
TREMOR	43
SURGERY	43
SINUS BRADYCARDIA	43
MITRAL VALVE DISEASE	43
BLINDNESS UNILATERAL	43
MULTIPLE FRACTURES	42
BLOOD PRESSURE INCREASED	42
ARTHRALGIA	42
SEPTIC SHOCK	41
HYPERHIDROSIS	41
FOOT FRACTURE	41
BACK PAIN	41
ABDOMINAL PAIN UPPER	41
VENTRICULAR ARRHYTHMIA	40
ORTHOPNOEA	40
NEUROPATHY PERIPHERAL	40
MOBILITY DECREASED	39
DRUG INEFFECTIVE	39
CAROTID ARTERY OCCLUSION	39
ACTIVITIES OF DAILY LIVING IMPAIRED	39
ABDOMINAL DISTENSION	39
HYPERCHOLESTEROLAEMIA	38
GENERALISED OEDEMA	38
GENERAL PHYSICAL HEALTH DETERIORATION	38
DIABETIC RETINOPATHY	38
DEMENTIA	38
APHASIA	38
DYSLIPIDAEMIA	37
ASCITES	37
AORTIC VALVE REPLACEMENT	37
PERICARDITIS	36
OXYGEN SUPPLEMENTATION	36
HYPOXIA	36
HEPATIC ENZYME INCREASED	36
URINARY TRACT INFECTION	35
UPPER LIMB FRACTURE	35
RESPIRATORY DISORDER	35
MEMORY IMPAIRMENT	35
EMBOLIC STROKE	35
HEART VALVE INCOMPETENCE	34
BLOOD TRIGLYCERIDES INCREASED	34
RASH	33
LOCAL SWELLING	33
BLOOD CREATININE INCREASED	33
ASPARTATE AMINOTRANSFERASE INCREASED	33
ALANINE AMINOTRANSFERASE INCREASED	33
THROMBOCYTOPENIA	32
ECONOMIC PROBLEM	32
CONFUSIONAL STATE	32
CARDIAC FLUTTER	32
ANKLE FRACTURE	32
ANEURYSM	32
PRURITUS	31
DECREASED ACTIVITY	31
CEREBRAL ISCHAEMIA	31
SUDDEN DEATH	30
SINUS TACHYCARDIA	30
HIP FRACTURE	30
HEART RATE DECREASED	30
GLYCOSYLATED HAEMOGLOBIN INCREASED	30
CIRCULATORY COLLAPSE	30
VIITH NERVE PARALYSIS	29
VERTIGO	29
STRESS	29
NERVE INJURY	29
LEFT ATRIAL DILATATION	29
DIALYSIS	29
CATARACT	29
CARDIAC FAILURE ACUTE	29
ANGIOPATHY	29
TREATMENT NONCOMPLIANCE	28
PYREXIA	27
PULMONARY CONGESTION	27
PERIPHERAL ARTERIAL OCCLUSIVE DISEASE	27
OBSTRUCTION	27
MYALGIA	27
GASTROINTESTINAL HAEMORRHAGE	27
EMOTIONAL DISORDER	27
DYSPHAGIA	27
ARTERIAL DISORDER	27
AORTIC ARTERIOSCLEROSIS	27
WHEEZING	26
SUBARACHNOID HAEMORRHAGE	26
QUALITY OF LIFE DECREASED	26
MALIGNANT HYPERTENSION	26
LIVER FUNCTION TEST ABNORMAL	26
DRUG INTERACTION	26
BASAL GANGLIA INFARCTION	26
AORTIC VALVE SCLEROSIS	26
AORTIC VALVE DISEASE	26
ANOREXIA	26
SUBDURAL HAEMATOMA	25
SHOCK	25
PANCREATITIS	25
HYPERGLYCAEMIA	25
HEPATIC STEATOSIS	25
HAEMOGLOBIN DECREASED	25
GASTRIC DISORDER	25
CELLULITIS	25
CARDIAC TAMPONADE	25
CARDIAC HYPERTROPHY	25
BRAIN STEM STROKE	25
PULMONARY FIBROSIS	24
PNEUMONIA ASPIRATION	24
HIGH DENSITY LIPOPROTEIN DECREASED	24
ERECTILE DYSFUNCTION	24
BRONCHITIS	24
BLOOD GLUCOSE DECREASED	24
BLOOD BILIRUBIN INCREASED	24
AORTIC ANEURYSM	24
LEFT VENTRICULAR FAILURE	23
HYPERTENSIVE EMERGENCY	23
HYPERTENSIVE CARDIOMYOPATHY	23
GAMMA-GLUTAMYLTRANSFERASE INCREASED	23
DEHYDRATION	23
ASTHMA	23
ANGIOGRAM	23
VENTRICULAR HYPOKINESIA	22
SCAR	22
RETINAL HAEMORRHAGE	22
PERCUTANEOUS CORONARY INTERVENTION	22
MUSCULOSKELETAL PAIN	22
MUSCULOSKELETAL DISORDER	22
CEREBRAL ARTERY OCCLUSION	22
ALOPECIA	22
VENTRICULAR DYSFUNCTION	21
TRAUMATIC LUNG INJURY	21
PULMONARY ARTERIAL HYPERTENSION	21
PRESYNCOPE	21
NORMOCHROMIC NORMOCYTIC ANAEMIA	21
MENTAL STATUS CHANGES	21
LEG AMPUTATION	21
HYPERTROPHIC CARDIOMYOPATHY	21
DYSARTHRIA	21
CORONARY ARTERY THROMBOSIS	21
SOMNOLENCE	20
OBESITY	20
MITRAL VALVE CALCIFICATION	20
CORONARY ARTERY INSUFFICIENCY	20
CONSTIPATION	20
BLOOD PRESSURE ABNORMAL	20
VISUAL FIELD DEFECT	19
RESPIRATORY DISTRESS	19
HYPERKALAEMIA	19
DIABETIC COMPLICATION	19
DECREASED APPETITE	19
ATRIAL TACHYCARDIA	19
RIB FRACTURE	18
POST PROCEDURAL COMPLICATION	18
MOVEMENT DISORDER	18
HAEMORRHAGE	18
COAGULOPATHY	18
BUNDLE BRANCH BLOCK	18
BLOOD UREA INCREASED	18
VISUAL DISTURBANCE	17
SUPRAVENTRICULAR EXTRASYSTOLES	17
STAPHYLOCOCCAL INFECTION	17
SKIN ULCER	17
NECK PAIN	17
MITRAL VALVE PROLAPSE	17
INFARCTION	17
HEPATIC ENCEPHALOPATHY	17
HEART VALVE REPLACEMENT	17
HAEMATOCRIT DECREASED	17
FEAR	17
WRIST FRACTURE	16
SWELLING FACE	16
OSTEOMYELITIS	16
LEUKOPENIA	16
HUMERUS FRACTURE	16
GASTROINTESTINAL DISORDER	16
EXTRASYSTOLES	16
ESSENTIAL HYPERTENSION	16
ARTERIOSPASM CORONARY	16
SYSTOLIC DYSFUNCTION	15
ROAD TRAFFIC ACCIDENT	15
RETINOPATHY	15
PHYSICAL DISABILITY	15
OVERDOSE	15
NON-CARDIAC CHEST PAIN	15
MULTIPLE INJURIES	15
MONOPLEGIA	15
MIGRAINE	15
MACULAR DEGENERATION	15
HYPOKALAEMIA	15
HYPERSENSITIVITY	15
HEPATOMEGALY	15
GASTROOESOPHAGEAL REFLUX DISEASE	15
ENCEPHALOPATHY	15
BLOOD GLUCOSE FLUCTUATION	15
ATELECTASIS	15
ANHEDONIA	15
SINUS ARRHYTHMIA	14
PANCYTOPENIA	14
NERVOUS SYSTEM DISORDER	14
MENTAL DISORDER	14
LOWER LIMB FRACTURE	14
LETHARGY	14
HYPERTRIGLYCERIDAEMIA	14
HEPATITIS	14
FACE OEDEMA	14
ENDOCARDITIS	14
DIPLOPIA	14
CORONARY ARTERY REOCCLUSION	14
ARRHYTHMIA SUPRAVENTRICULAR	14
VENTRICULAR HYPERTROPHY	13
SLEEP DISORDER	13
Seizure	13
RENAL ARTERY STENOSIS	13
RED BLOOD CELL COUNT DECREASED	13
PULSELESS ELECTRICAL ACTIVITY	13
PANIC ATTACK	13
METABOLIC ACIDOSIS	13
IRON DEFICIENCY ANAEMIA	13
INTRACRANIAL ANEURYSM	13
INFECTION	13
HYPONATRAEMIA	13
HEART TRANSPLANT	13
GLAUCOMA	13
FEMUR FRACTURE	13
DYSPNOEA PAROXYSMAL NOCTURNAL	13
DISORIENTATION	13
DISEASE PROGRESSION	13
DILATATION ATRIAL	13
DEPRESSED LEVEL OF CONSCIOUSNESS	13
BLOOD CREATINE PHOSPHOKINASE INCREASED	13
BLOOD ALKALINE PHOSPHATASE INCREASED	13
BLISTER	13
Basal ganglia stroke	13
ARTHRITIS	13
ACCELERATED HYPERTENSION	13
TYPE 2 DIABETES MELLITUS	12
TACHYARRHYTHMIA	12
PULMONARY VALVE INCOMPETENCE	12
PRODUCTIVE COUGH	12
POLLAKIURIA	12
PANCREATIC CARCINOMA	12
NERVOUSNESS	12
MITRAL VALVE REPAIR	12
MENTAL IMPAIRMENT	12
LUNG INFILTRATION	12
ISCHAEMIC CEREBRAL INFARCTION	12
INTESTINAL ISCHAEMIA	12
HYPOKINESIA	12
FEELING ABNORMAL	12
EYE PAIN	12
DYSURIA	12
CONTUSION	12
COGNITIVE DISORDER	12
Chronic kidney disease	12
CHILLS	12
BLOOD LACTATE DEHYDROGENASE INCREASED	12
Basal ganglia haemorrhage	12
ARTERIAL STENOSIS	12
AORTIC DISSECTION	12
ACUTE RESPIRATORY DISTRESS SYNDROME	12
TROPONIN INCREASED	11
RHABDOMYOLYSIS	11
RADIUS FRACTURE	11
PROSTATE CANCER	11
MYOCARDITIS	11
MUSCULOSKELETAL CHEST PAIN	11
MITRAL VALVE STENOSIS	11
IMPAIRED WORK ABILITY	11
FLATULENCE	11
EYE INJURY	11
EYE HAEMORRHAGE	11
EXERCISE TOLERANCE DECREASED	11
ELECTROCARDIOGRAM QT PROLONGED	11
DYSPEPSIA	11
DRUG EXPOSURE DURING PREGNANCY	11
DILATATION VENTRICULAR	11
CHOLELITHIASIS	11
BRADYARRHYTHMIA	11
ATRIAL SEPTAL DEFECT	11
ATAXIA	11
Arterial stent insertion	11
UNRESPONSIVE TO STIMULI	10
TRANSAMINASES INCREASED	10
RESUSCITATION	10
RALES	10
PULSE ABSENT	10
PORTAL HYPERTENSION	10
PALLOR	10
NEUTROPENIA	10
LIMB INJURY	10
INCREASED APPETITE	10
IMMOBILE	10
HYPERTENSIVE ENCEPHALOPATHY	10
HEPATOTOXICITY	10
HEPATOCELLULAR DAMAGE	10
HEPATIC NECROSIS	10
HEAD INJURY	10
HALLUCINATION	10
FACIAL PALSY	10
ELECTROCARDIOGRAM ST SEGMENT ELEVATION	10
DRUG HYPERSENSITIVITY	10
DISTURBANCE IN ATTENTION	10
DEMENTIA ALZHEIMER'S TYPE	10
DEFORMITY	10
CEREBRAL THROMBOSIS	10
CEREBELLAR HAEMORRHAGE	10
CATHETER PLACEMENT	10
ASPIRATION	10
AGGRESSION	10
ABDOMINAL DISCOMFORT	10
VARICES OESOPHAGEAL	9
TIBIA FRACTURE	9
THYROID DISORDER	9
SPINAL COMPRESSION FRACTURE	9
PULMONARY THROMBOSIS	9
POOR PERIPHERAL CIRCULATION	9
PNEUMOTHORAX	9
PLATELET COUNT DECREASED	9
PHARMACEUTICAL PRODUCT COMPLAINT	9
Peripheral swelling	9
PERIPHERAL ISCHAEMIA	9
OSTEOPENIA	9
ORTHOSTATIC HYPOTENSION	9
MICROCYTIC ANAEMIA	9
MEDICATION ERROR	9
LUNG NEOPLASM MALIGNANT	9
LIFE EXPECTANCY SHORTENED	9
LIBIDO DECREASED	9
INFLAMMATION	9
HAEMATOMA	9
GANGRENE	9
ERYTHEMA	9
ELECTROLYTE IMBALANCE	9
DYSSTASIA	9
DYSPNOEA EXACERBATED	9
DIABETIC KETOACIDOSIS	9
DELIRIUM	9
CEREBRAL ATROPHY	9
CAROTID ARTERIOSCLEROSIS	9
CARDIAC STRESS TEST ABNORMAL	9
CARDIAC ANEURYSM	9
BONE DISORDER	9
APPARENT DEATH	9
ANOXIC ENCEPHALOPATHY	9
ANGIONEUROTIC OEDEMA	9
ANAEMIA MACROCYTIC	9
ACIDOSIS	9
WHITE BLOOD CELL COUNT DECREASED	8
TRANSFUSION	8
TOE AMPUTATION	8
SUICIDAL IDEATION	8
SUBDURAL HAEMORRHAGE	8
SINUS DISORDER	8
SINUS ARREST	8
SENSORY LOSS	8
RETINAL DETACHMENT	8
RENAL TRANSPLANT	8
PRINZMETAL ANGINA	8
PICKWICKIAN SYNDROME	8
OSTEOPOROSIS	8
OSTEOGENESIS IMPERFECTA	8
NOCTURIA	8
NEOPLASM MALIGNANT	8
MOTOR DYSFUNCTION	8
MICTURITION DISORDER	8
MACULOPATHY	8
LOBAR PNEUMONIA	8
LACRIMATION INCREASED	8
JUGULAR VEIN DISTENSION	8
HAEMATURIA	8
HAEMATEMESIS	8
GRAND MAL CONVULSION	8
GASTRITIS	8
GASTRIC HAEMORRHAGE	8
FIBULA FRACTURE	8
FEAR OF DEATH	8
ELECTROCARDIOGRAM CHANGE	8
DRESSLER'S SYNDROME	8
DIABETIC NEUROPATHY	8
DIABETIC NEPHROPATHY	8
CYSTITIS	8
CYANOSIS	8
COLON CANCER	8
CHROMATURIA	8
CEREBRAL ARTERIOSCLEROSIS	8
BRONCHOPNEUMONIA	8
BONE PAIN	8
BLOOD PRESSURE INADEQUATELY CONTROLLED	8
BLOOD POTASSIUM INCREASED	8
BLADDER CANCER	8
ARTHROPATHY	8
ADVERSE DRUG REACTION	8
VASCULAR OCCLUSION	7
VASCULAR DEMENTIA	7
URTICARIA	7
UPPER RESPIRATORY TRACT INFECTION	7
THROMBOTIC STROKE	7
TERMINAL STATE	7
SUICIDE ATTEMPT	7
STRESS FRACTURE	7
STRESS CARDIOMYOPATHY	7
STAPHYLOCOCCAL SEPSIS	7
SPLENOMEGALY	7
SPINAL FRACTURE	7
RETINAL VEIN OCCLUSION	7
RETINAL DISORDER	7
REFUSAL OF TREATMENT BY PATIENT	7
RED BLOOD CELL SEDIMENTATION RATE INCREASED	7
PNEUMONITIS	7
PANCREATITIS ACUTE	7
OVERWEIGHT	7
OPTIC ISCHAEMIC NEUROPATHY	7
NEPHROLITHIASIS	7
METASTASES TO LIVER	7
LACTIC ACIDOSIS	7
IRRITABILITY	7
INFLUENZA LIKE ILLNESS	7
INCONTINENCE	7
IN-STENT CORONARY ARTERY RESTENOSIS	7
HEPATITIS ACUTE	7
HEART DISEASE CONGENITAL	7
HAEMOPTYSIS	7
GASTROINTESTINAL PAIN	7
FEMORAL ARTERY OCCLUSION	7
EYE SWELLING	7
EPISTAXIS	7
Embolic cerebral infarction	7
DISCOMFORT	7
DEVICE OCCLUSION	7
DEVICE MALFUNCTION	7
DEAFNESS	7
COORDINATION ABNORMAL	7
CONDUCTION DISORDER	7
BRAIN STEM HAEMORRHAGE	7
BRAIN OEDEMA	7
BRAIN DEATH	7
BLOOD IRON DECREASED	7
ARTERIAL THERAPEUTIC PROCEDURE	7
Acute kidney injury	7
ACCIDENTAL OVERDOSE	7
WHITE BLOOD CELL COUNT INCREASED	6
VITREOUS HAEMORRHAGE	6
VENOUS INSUFFICIENCY	6
VASCULAR INJURY	6
URINE OUTPUT DECREASED	6
URINARY INCONTINENCE	6
TORSADE DE POINTES	6
SEXUAL DYSFUNCTION	6
RHINORRHOEA	6
RETINAL OEDEMA	6
RECTAL HAEMORRHAGE	6
PROTHROMBIN TIME PROLONGED	6
PROTEINURIA	6
PROCEDURAL COMPLICATION	6
POSTPERICARDIOTOMY SYNDROME	6
PLEURISY	6
PITTING OEDEMA	6
PERICARDITIS CONSTRICTIVE	6
PATHOLOGICAL FRACTURE	6
PAPILLOEDEMA	6
OSTEOARTHRITIS	6
NIGHT BLINDNESS	6
NASOPHARYNGITIS	6
MUSCULOSKELETAL STIFFNESS	6
LUNG NEOPLASM	6
LOSS OF LIBIDO	6
LOSS OF EMPLOYMENT	6
LIVER TRANSPLANT	6
KIDNEY INFECTION	6
INCREASED TENDENCY TO BRUISE	6
HEPATORENAL SYNDROME	6
HAND FRACTURE	6
HAEMOLYTIC ANAEMIA	6
GASTRITIS EROSIVE	6
ENDOCARDITIS BACTERIAL	6
EMPHYSEMA	6
DRY MOUTH	6
CORONARY ARTERY RESTENOSIS	6
CHRONIC RESPIRATORY FAILURE	6
CARPAL TUNNEL SYNDROME	6
CARDIAC ENZYMES INCREASED	6
BREAST CANCER	6
BRAIN NATRIURETIC PEPTIDE INCREASED	6
BRAIN HYPOXIA	6
BLOOD PRESSURE SYSTOLIC INCREASED	6
BLOOD PRESSURE DECREASED	6
BLOOD GLUCOSE ABNORMAL	6
BLINDNESS TRANSIENT	6
BACK INJURY	6
ATRIAL THROMBOSIS	6
AORTIC VALVE CALCIFICATION	6
AMPUTATION	6
WALKING DISABILITY	5
UNEVALUABLE EVENT	5
THROMBOPHLEBITIS	5
SUBCLAVIAN ARTERY STENOSIS	5
SINUSITIS	5
RESPIRATORY TRACT CONGESTION	5
RESPIRATORY ACIDOSIS	5
RENAL TUBULAR NECROSIS	5
RENAL CANCER	5
RASH GENERALISED	5
PULMONARY FUNCTION TEST DECREASED	5
POSTINFARCTION ANGINA	5
POLYNEUROPATHY	5
PERIPHERAL COLDNESS	5
PAIN IN JAW	5
ORGAN FAILURE	5
OPEN ANGLE GLAUCOMA	5
OCULAR HYPERAEMIA	5
Nodal arrhythmia	5
NEUROLOGICAL SYMPTOM	5
MYOCARDIAL RUPTURE	5
MUSCLE DISORDER	5
MELAENA	5
MALE SEXUAL DYSFUNCTION	5
LYMPHADENOPATHY	5
LOCALISED OEDEMA	5
LOCALISED INFECTION	5
LIPIDS INCREASED	5
LEUKOCYTOSIS	5
Left atrial enlargement	5
JAUNDICE CHOLESTATIC	5
INTRAVENTRICULAR HAEMORRHAGE	5
INTRAOCULAR PRESSURE INCREASED	5
INTERMITTENT CLAUDICATION	5
HYPOCHROMIC ANAEMIA	5
HEPATIC FUNCTION ABNORMAL	5
HAEMATOCHEZIA	5
GALLOP RHYTHM PRESENT	5
GALLBLADDER DISORDER	5
FEELING HOT	5
FAILURE TO THRIVE	5
FAECAL INCONTINENCE	5
EYE OEDEMA	5
ENDOCARDITIS STAPHYLOCOCCAL	5
ELECTROCARDIOGRAM T WAVE INVERSION	5
ELECTROCARDIOGRAM T WAVE ABNORMAL	5
EJECTION FRACTION ABNORMAL	5
DYSPNOEA AT REST	5
DYSGEUSIA	5
DRUG TOXICITY	5
DRUG ADMINISTRATION ERROR	5
DIAPHRAGMATIC PARALYSIS	5
DIABETIC EYE DISEASE	5
DEPRESSED MOOD	5
DEAFNESS UNILATERAL	5
CRYPTOGENIC CIRRHOSIS	5
CORONARY ARTERY EMBOLISM	5
COR PULMONALE CHRONIC	5
CONJUNCTIVAL HAEMORRHAGE	5
COMPLETED SUICIDE	5
CHRONIC LYMPHOCYTIC LEUKAEMIA	5
CHOLECYSTECTOMY	5
CEREBROVASCULAR INSUFFICIENCY	5
CEREBRAL HYPOPERFUSION	5
CAROTID ENDARTERECTOMY	5
CARDIOVERSION	5
CARDIAC VENTRICULOGRAM LEFT	5
BURNING SENSATION	5
BUNDLE BRANCH BLOCK BILATERAL	5
BLOOD SODIUM DECREASED	5
BLOOD DISORDER	5
BLADDER DISORDER	5
BIPOLAR DISORDER	5
AZOTAEMIA	5
ARTERIOGRAM CORONARY	5
ARTERIAL BYPASS OPERATION	5
AORTIC CALCIFICATION	5
ALTERED STATE OF CONSCIOUSNESS	5
AGITATION	5
ACUTE HEPATIC FAILURE	5
ABORTION SPONTANEOUS	5
WOUND INFECTION	4
WHEELCHAIR USER	4
VERTEBRAL ARTERY OCCLUSION	4
VENTRICULAR TACHYARRHYTHMIA	4
VENTRICULAR ASYSTOLE	4
VENOUS THROMBOSIS	4
VENOUS OCCLUSION	4
VASCULAR GRAFT OCCLUSION	4
VARICOSE VEIN	4
UPPER GASTROINTESTINAL HAEMORRHAGE	4
ULCER	4
THROMBOSIS IN DEVICE	4
THIRST	4
THERAPEUTIC RESPONSE UNEXPECTED	4
THALAMUS HAEMORRHAGE	4
STERNAL FRACTURE	4
STATUS EPILEPTICUS	4
SKIN DISCOLOURATION	4
SCAPULA FRACTURE	4
RETINAL TEAR	4
RETINAL EXUDATES	4
RESTLESS LEGS SYNDROME	4
RENAL HAEMORRHAGE	4
POSTMENOPAUSAL HAEMORRHAGE	4
POST PROCEDURAL MYOCARDIAL INFARCTION	4
PETECHIAE	4
PERONEAL NERVE PALSY	4
PERFORMANCE STATUS DECREASED	4
PELVIC FRACTURE	4
PARKINSON'S DISEASE	4
OXYGEN SATURATION DECREASED	4
OCULAR ICTERUS	4
NEUROPATHIC ARTHROPATHY	4
NEURALGIA	4
MYOPATHY	4
Myocardial necrosis marker increased	4
MYELODYSPLASTIC SYNDROME	4
MUSCULOSKELETAL DISCOMFORT	4
MITRAL VALVE SCLEROSIS	4
METASTASES TO CENTRAL NERVOUS SYSTEM	4
LYMPHOMA	4
LUNG CANCER METASTATIC	4
LOWER RESPIRATORY TRACT INFECTION	4
LOW DENSITY LIPOPROTEIN INCREASED	4
LIPASE INCREASED	4
Limb discomfort	4
Lateral medullary syndrome	4
LACERATION	4
JOINT INJURY	4
INTESTINAL OBSTRUCTION	4
INTERSTITIAL LUNG DISEASE	4
INTERNATIONAL NORMALISED RATIO INCREASED	4
INCORRECT DOSE ADMINISTERED	4
IMPAIRED GASTRIC EMPTYING	4
HYPOVOLAEMIA	4
HYPOGLYCAEMIC COMA	4
HYPERSOMNIA	4
HOT FLUSH	4
HOSPITALISATION	4
HIATUS HERNIA	4
HERNIA	4
HEPATITIS CHOLESTATIC	4
HEPATIC NEOPLASM MALIGNANT	4
HEMIANOPIA HOMONYMOUS	4
HEART RATE ABNORMAL	4
HAEMOTHORAX	4
Haemorrhagic infarction	4
GOUT	4
GASTRIC ULCER	4
ENCEPHALOMALACIA	4
EMBOLISM ARTERIAL	4
EMBOLISM	4
ELECTROCARDIOGRAM POOR R-WAVE PROGRESSION	4
ECHOCARDIOGRAM ABNORMAL	4
DRUG DISPENSING ERROR	4
DIPLEGIA	4
DIFFICULTY IN WALKING	4
CREPITATIONS	4
COLD SWEAT	4
CHEST X-RAY ABNORMAL	4
CEREBRAL SMALL VESSEL ISCHAEMIC DISEASE	4
CEREBRAL ARTERY STENOSIS	4
CAROTID ARTERY STENT INSERTION	4
CAROTID ARTERY ANEURYSM	4
CARDIAC VENTRICULOGRAM	4
CARDIAC OUTPUT DECREASED	4
CARDIAC FUNCTION DISTURBANCE POSTOPERATIVE	4
C-REACTIVE PROTEIN INCREASED	4
BRONCHOSPASM	4
BREAST CANCER METASTATIC	4
Brain herniation	4
BONE DENSITY DECREASED	4
BLOOD URIC ACID INCREASED	4
BLOOD CHOLESTEROL ABNORMAL	4
BLOOD AMYLASE INCREASED	4
BEDRIDDEN	4
ARTERIOVENOUS MALFORMATION	4
ARTERIAL INJURY	4
AORTIC VALVE REPAIR	4
ANGER	4
AFFECT LABILITY	4
ACCIDENTAL EXPOSURE	4
ABDOMINAL PAIN LOWER	4
WEIGHT LOSS POOR	3
WEIGHT FLUCTUATION	3
VITREOUS FLOATERS	3
VITAMIN B12 DEFICIENCY	3
VITAMIN B12 DECREASED	3
VERTEBROBASILAR INSUFFICIENCY	3
VASCULAR PSEUDOANEURYSM	3
VASCULAR CALCIFICATION	3
UROSEPSIS	3
UNINTENDED PREGNANCY	3
TYPE 1 DIABETES MELLITUS	3
TROPONIN I INCREASED	3
TRICUSPID VALVE DISEASE	3
TOOTH EXTRACTION	3
THROAT TIGHTNESS	3
THERMAL BURN	3
SWOLLEN TONGUE	3
SUBACUTE ENDOCARDITIS	3
STOMACH DISCOMFORT	3
SPLENIC ABSCESS	3
SPINAL DISORDER	3
SPINAL COLUMN STENOSIS	3
SODIUM RETENTION	3
SMALL INTESTINAL OBSTRUCTION	3
Small cell lung cancer	3
SKIN TIGHTNESS	3
SKIN EXFOLIATION	3
SERUM FERRITIN DECREASED	3
SEPSIS SYNDROME	3
RIGHT VENTRICULAR HYPERTROPHY	3
RIGHT VENTRICULAR DYSFUNCTION	3
RHEUMATOID ARTHRITIS	3
REVERSIBLE ISCHAEMIC NEUROLOGICAL DEFICIT	3
RETROPERITONEAL HAEMORRHAGE	3
RETINAL ARTERY OCCLUSION	3
RETINAL ANEURYSM	3
RESTLESSNESS	3
RESPIRATORY TRACT INFECTION	3
RENAL VESSEL DISORDER	3
RENAL CELL CARCINOMA STAGE UNSPECIFIED	3
PYELONEPHRITIS	3
Pulmonary haemorrhage	3
PSORIASIS	3
PROTHROMBIN LEVEL DECREASED	3
PROCEDURAL PAIN	3
POST-TRAUMATIC STRESS DISORDER	3
PORTAL VEIN THROMBOSIS	3
POOR QUALITY SLEEP	3
PNEUMONIA BACTERIAL	3
PERIPARTUM CARDIOMYOPATHY	3
Pericardial haemorrhage	3
PERICARDIAL EXCISION	3
PERICARDIAL DISEASE	3
PATELLA FRACTURE	3
PAROTID GLAND ENLARGEMENT	3
PARKINSONISM	3
PARESIS	3
PARAPLEGIA	3
PARAESTHESIA ORAL	3
PANCREATITIS CHRONIC	3
PANCREATIC INSUFFICIENCY	3
PANCREATIC DISORDER	3
ORTHOSTATIC HYPERTENSION	3
OPTIC ATROPHY	3
OPEN WOUND	3
OESOPHAGITIS	3
OEDEMA GENITAL	3
OEDEMA DUE TO CARDIAC DISEASE	3
OBSTRUCTIVE AIRWAYS DISORDER	3
NON-HODGKIN'S LYMPHOMA	3
NODAL RHYTHM	3
NIGHT SWEATS	3
NEOPLASM	3
MUSCLE TIGHTNESS	3
MOOD SWINGS	3
MOOD ALTERED	3
MITRAL VALVE REPLACEMENT	3
METASTASIS	3
METAMORPHOPSIA	3
METABOLIC DISORDER	3
MACROCYTOSIS	3
LIP SWELLING	3
LIGAMENT INJURY	3
LACRIMATION DECREASED	3
JOINT SPRAIN	3
INADEQUATE DIET	3
IMPAIRED SELF-CARE	3
IMPAIRED HEALING	3
ILEUS	3
HYPOTHYROIDISM	3
HYPOAESTHESIA FACIAL	3
HYPOACUSIS	3
HYPERVOLAEMIA	3
HYPERTHYROIDISM	3
HYPERPHAGIA	3
HYPERCAPNIA	3
Hydrocephalus	3
HUNGER	3
HIP SURGERY	3
HEPATITIS C	3
HEPATIC PAIN	3
HEPATIC MASS	3
HEPATIC FIBROSIS	3
Heart valve stenosis	3
HEART TRANSPLANT REJECTION	3
HEARING IMPAIRED	3
Haemorrhagic cerebral infarction	3
HAEMODIALYSIS	3
GUILLAIN-BARRE SYNDROME	3
GRIP STRENGTH DECREASED	3
GASTRIC CANCER	3
FRACTURED COCCYX	3
FORMICATION	3
FLUID IMBALANCE	3
FIBROMYALGIA	3
FEELING DRUNK	3
FEELING COLD	3
FAT TISSUE INCREASED	3
Facial bones fracture	3
EYELID PTOSIS	3
EYELID OEDEMA	3
EYEBALL AVULSION	3
EXCORIATION	3
ELECTROMECHANICAL DISSOCIATION	3
ELECTROCARDIOGRAM ST-T SEGMENT ABNORMAL	3
ELECTROCARDIOGRAM ST SEGMENT DEPRESSION	3
EATING DISORDER	3
DYSKINESIA	3
DYSAESTHESIA	3
DISSEMINATED INTRAVASCULAR COAGULATION	3
DISEASE RECURRENCE	3
DISEASE COMPLICATION	3
DIABETIC RETINAL OEDEMA	3
DIABETIC COMA	3
DERMATITIS ALLERGIC	3
CYSTOID MACULAR OEDEMA	3
CREATININE RENAL CLEARANCE INCREASED	3
CORONARY OSTIAL STENOSIS	3
CONCUSSION	3
COLON NEOPLASM	3
COLITIS ISCHAEMIC	3
CLOSTRIDIUM DIFFICILE COLITIS	3
CHRONIC HEPATIC FAILURE	3
CHOROIDAL NEOVASCULARISATION	3
CHOLESTASIS	3
CHOLECYSTITIS ACUTE	3
CHOKING	3
CEREBRAL HAEMATOMA	3
Cardiopulmonary bypass	3
CARDIAC CIRRHOSIS	3
CARDIAC ABLATION	3
BREAST PAIN	3
BRAIN NEOPLASM	3
BLOOD CHOLESTEROL DECREASED	3
BLOOD ALBUMIN INCREASED	3
BLOOD ALBUMIN DECREASED	3
BIOPSY LIVER ABNORMAL	3
BIOPSY BONE MARROW ABNORMAL	3
BILE DUCT STONE	3
BENIGN PROSTATIC HYPERPLASIA	3
Basilar artery occlusion	3
BACTERIAL SEPSIS	3
BACTERAEMIA	3
BACK DISORDER	3
AUTOIMMUNE DISORDER	3
ATROPHY	3
ATHEROSCLEROSIS	3
ASPHYXIA	3
APOLIPOPROTEIN A-I DECREASED	3
APNOEA	3
AORTIC DILATATION	3
ANTICOAGULANT THERAPY	3
ANGIOEDEMA	3
ANAPHYLACTIC REACTION	3
ALCOHOL USE	3
ALBUMINURIA	3
AKINESIA	3
AFFECTIVE DISORDER	3
Adenocarcinoma of colon	3
ABNORMAL SENSATION IN EYE	3
ABDOMINAL SYMPTOM	3
YELLOW SKIN	2
WOUND INFECTION STAPHYLOCOCCAL	2
WOUND DEHISCENCE	2
Vomiting projectile	2
VOCAL CORD PARALYSIS	2
VITREOUS DETACHMENT	2
VITH NERVE PARALYSIS	2
VITAMIN D DEFICIENCY	2
VISUAL ACUITY TESTS ABNORMAL	2
VIRAL INFECTION	2
VERTEBRAL ARTERY STENOSIS	2
VENTRICULAR SEPTAL DEFECT	2
Ventricular flutter	2
VENTRICULAR FAILURE	2
VENTRICLE RUPTURE	2
VENOUS PRESSURE JUGULAR INCREASED	2
VASCULITIS CEREBRAL	2
VASCULITIS	2
VASCULAR STENOSIS	2
VAGINAL HAEMORRHAGE	2
UVEITIS	2
UTERINE LEIOMYOSARCOMA	2
UTERINE CANCER	2
URINARY RETENTION	2
URINARY BLADDER HAEMORRHAGE	2
ULNA FRACTURE	2
Ulcer haemorrhage	2
TRAUMATIC BRAIN INJURY	2
TRANSITIONAL CELL CARCINOMA	2
TRACHEOSTOMY	2
TOXICITY TO VARIOUS AGENTS	2
Total lung capacity decreased	2
TOOTH LOSS	2
TONGUE BITING	2
TINNITUS	2
THYROIDITIS	2
THERAPY NON-RESPONDER	2
TENDON PAIN	2
TEMPERATURE REGULATION DISORDER	2
TACHYPNOEA	2
SYSTOLIC HYPERTENSION	2
Subendocardial ischaemia	2
STRIDOR	2
STREPTOCOCCAL INFECTION	2
STOMACH MASS	2
STEVENS-JOHNSON SYNDROME	2
STERNOTOMY	2
SPUTUM DISCOLOURED	2
SPINAL CORD HAEMORRHAGE	2
SOPOR	2
SKIN FISSURES	2
SKIN DISORDER	2
SHOCK HYPOGLYCAEMIC	2
SENSE OF OPPRESSION	2
SCREAMING	2
SCOTOMA	2
RIGHT ATRIAL DILATATION	2
RHEUMATIC HEART DISEASE	2
RETINAL VASCULAR DISORDER	2
RETINAL TELANGIECTASIA	2
RETINAL SCAR	2
RETINAL ARTERY EMBOLISM	2
RETICULOCYTE COUNT DECREASED	2
RETCHING	2
RENAL CYST	2
RENAL ARTERY STENT PLACEMENT	2
REGURGITATION	2
RED BLOOD CELL COUNT ABNORMAL	2
Quadriplegia	2
QRS AXIS ABNORMAL	2
PYELONEPHRITIS ACUTE	2
Pulmonary infarction	2
PULMONARY GRANULOMA	2
PULMONARY ARTERIAL PRESSURE INCREASED	2
PSYCHOTIC DISORDER	2
PSEUDOPHAKIA	2
PRURITUS GENERALISED	2
PROTEIN TOTAL DECREASED	2
PROSTATE CANCER METASTATIC	2
PRODUCT QUALITY ISSUE	2
PRESBYOPIA	2
POSTOPERATIVE RESPIRATORY DISTRESS	2
POSTOPERATIVE RENAL FAILURE	2
POSTNASAL DRIP	2
POSTICTAL PARALYSIS	2
POLYURIA	2
POLYMYALGIA RHEUMATICA	2
POLYCYTHAEMIA	2
PNEUMONIA NECROTISING	2
Pneumonia klebsiella	2
PLEURITIC PAIN	2
PLATELET COUNT INCREASED	2
PHOTOSENSITIVITY REACTION	2
PHOTOPHOBIA	2
PHOTOCOAGULATION	2
PHLEBITIS	2
PHARYNGOLARYNGEAL PAIN	2
PHARYNGEAL OEDEMA	2
Pharyngeal injury	2
PERITONITIS BACTERIAL	2
PERITONITIS	2
PERIRECTAL ABSCESS	2
Peripheral venous disease	2
Peripheral artery stenosis	2
Pericardial rub	2
PERICARDIAL DRAINAGE	2
PERICARDIAL CALCIFICATION	2
Penile swelling	2
PEMPHIGOID	2
PATENT DUCTUS ARTERIOSUS	2
PAROTITIS	2
PARANOIA	2
PANCREATIC CARCINOMA METASTATIC	2
PANCREATIC CALCIFICATION	2
PAINFUL RESPIRATION	2
OSTEONECROSIS	2
OROPHARYNGEAL SWELLING	2
ORAL DISORDER	2
ORAL DISCOMFORT	2
OPTIC NERVE CUPPING	2
Onychomadesis	2
OLIGURIA	2
OFF LABEL USE	2
OESOPHAGEAL VARICES HAEMORRHAGE	2
OCULAR ISCHAEMIC SYNDROME	2
NYSTAGMUS	2
NUCLEAR MAGNETIC RESONANCE IMAGING BRAIN ABNORMAL	2
NON-OBSTRUCTIVE CARDIOMYOPATHY	2
NOCTURNAL DYSPNOEA	2
NO THERAPEUTIC RESPONSE	2
NEUROPATHY	2
Nephrotic syndrome	2
Nephrosclerosis	2
NEPHRITIS	2
NECROSIS	2
MYOGLOBIN BLOOD INCREASED	2
MYOCARDIAL STRAIN	2
MYOCARDIAL FIBROSIS	2
MUSCULAR DYSTROPHY	2
MUSCLE SWELLING	2
MUSCLE INJURY	2
MUSCLE ATROPHY	2
MULTIPLE ALLERGIES	2
MOUTH HAEMORRHAGE	2
MOTION SICKNESS	2
MIDDLE INSOMNIA	2
MICTURITION URGENCY	2
MICROANGIOPATHY	2
Mesenteric artery stenosis	2
Mental disability	2
Megacolon	2
MEAN CELL VOLUME INCREASED	2
MEAN CELL VOLUME DECREASED	2
LYMPHOPENIA	2
LYMPHOEDEMA	2
LOCALISED OSTEOARTHRITIS	2
LIVER ABSCESS	2
LIPOMA	2
Ligament sprain	2
LERICHE SYNDROME	2
LARYNGEAL OEDEMA	2
LARYNGEAL INJURY	2
Labile blood pressure	2
KNEE ARTHROPLASTY	2
KLEBSIELLA SEPSIS	2
KLEBSIELLA INFECTION	2
KETOACIDOSIS	2
JOINT STIFFNESS	2
IRON DEFICIENCY	2
INTESTINAL HAEMORRHAGE	2
INTERVERTEBRAL DISC DEGENERATION	2
INTENTIONAL OVERDOSE	2
INSULIN RESISTANCE	2
INCREASED UPPER AIRWAY SECRETION	2
INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION	2
IMPAIRED DRIVING ABILITY	2
Immune system disorder	2
IDIOPATHIC THROMBOCYTOPENIC PURPURA	2
HYPOXIC ENCEPHALOPATHY	2
HYPOTONIA	2
Hypoaesthesia oral	2
HYPERTROPHY	2
HYPERTENSIVE NEPHROPATHY	2
HYPEROSMOLAR STATE	2
Hypercoagulation	2
HYPERAEMIA	2
HEPATOSPLENOMEGALY	2
HEPATITIS E	2
HEPATITIS B	2
HEPATITIS A	2
HEPATIC NEOPLASM	2
HEPATIC CONGESTION	2
Hepatic cancer	2
HEPATIC ATROPHY	2
Heart valve operation	2
HAEMORRHOIDS	2
HAEMORRHAGIC DISORDER	2
HAEMORRHAGIC DIATHESIS	2
GRAVITATIONAL OEDEMA	2
GOITRE	2
GLYCOSYLATED HAEMOGLOBIN DECREASED	2
GLOSSODYNIA	2
GLOMERULAR FILTRATION RATE DECREASED	2
GINGIVAL BLEEDING	2
Generalised tonic-clonic seizure	2
GASTROSTOMY	2
GALLBLADDER OPERATION	2
FRUSTRATION	2
FRACTURE NONUNION	2
FLANK PAIN	2
FINGER AMPUTATION	2
FEMORAL ARTERIAL STENOSIS	2
FEAR OF DISEASE	2
FAECES DISCOLOURED	2
FAECAL OCCULT BLOOD POSITIVE	2
EYE PRURITUS	2
ERYTHROSIS	2
EPILEPSY	2
ENURESIS	2
ELECTROCARDIOGRAM ST-T CHANGE	2
ELECTROCARDIOGRAM ST SEGMENT ABNORMAL	2
ELECTROCARDIOGRAM REPOLARISATION ABNORMALITY	2
Electrocardiogram	2
ECZEMA	2
ECCHYMOSIS	2
ECG SIGNS OF MYOCARDIAL ISCHAEMIA	2
EAR PAIN	2
DYSPHONIA	2
DRY EYE	2
DRUG SCREEN POSITIVE	2
DRUG EFFECT DECREASED	2
DIVORCED	2
DIVERTICULUM	2
DIVERTICULITIS	2
DIABETIC MICROANGIOPATHY	2
DIABETIC GASTROPARESIS	2
DIABETIC FOOT	2
DIABETIC CARDIOMYOPATHY	2
DEVICE RELATED INFECTION	2
Defect conduction intraventricular	2
DECUBITUS ULCER	2
DECREASED INTEREST	2
CYTOLYTIC HEPATITIS	2
CUSHING'S SYNDROME	2
CRYING	2
COSTOCHONDRITIS	2
Coronary bypass thrombosis	2
CORONARY ARTERY ATHEROSCLEROSIS	2
Cor pulmonale acute	2
CONJUNCTIVITIS	2
COMPUTERISED TOMOGRAM ABNORMAL	2
COMPRESSION FRACTURE	2
COMPLEX PARTIAL SEIZURES	2
COMMUNICATION DISORDER	2
CLAVICLE FRACTURE	2
CHRONIC OBSTRUCTIVE AIRWAYS DISEASE EXACERBATED	2
CHOLECYSTITIS	2
CHOLANGITIS	2
Cholangiocarcinoma	2
CHANGE OF BOWEL HABIT	2
CEREBRAL MICROANGIOPATHY	2
Cerebral circulatory failure	2
Cerebellar haematoma	2
Cerebellar atrophy	2
CEREBELLAR ATAXIA	2
CENTRAL NERVOUS SYSTEM LESION	2
CATHETER RELATED COMPLICATION	2
CARDIOVASCULAR DECONDITIONING	2
Cardiorenal syndrome	2
Cardiomyopathy acute	2
CARDIOACTIVE DRUG LEVEL DECREASED	2
CARDIO-RESPIRATORY DISTRESS	2
Cardiac ventricular thrombosis	2
CARDIAC STRESS TEST	2
CARDIAC INFECTION	2
CANDIDIASIS	2
CALCULUS BLADDER	2
CACHEXIA	2
BRONCHIECTASIS	2
BRONCHIAL HYPERREACTIVITY	2
BREATH SOUNDS ABNORMAL	2
BREAST NEOPLASM	2
BREAST MASS	2
BRAIN SCAN ABNORMAL	2
BONE MARROW FAILURE	2
BONE MARROW DEPRESSION	2
Bone loss	2
BODY TEMPERATURE INCREASED	2
BODY TEMPERATURE DECREASED	2
BLOOD URINE PRESENT	2
BLOOD TRIGLYCERIDES ABNORMAL	2
Blood pressure fluctuation	2
BLOOD PRESSURE DIASTOLIC DECREASED	2
BLOOD PRESSURE	2
BLOOD POTASSIUM DECREASED	2
BLOOD CREATINE PHOSPHOKINASE MB INCREASED	2
BLOOD COUNT ABNORMAL	2
BLOOD CHLORIDE DECREASED	2
BLOOD BICARBONATE INCREASED	2
BLINDNESS CORTICAL	2
BLADDER CANCER STAGE IV	2
BILIRUBIN CONJUGATED INCREASED	2
BILE DUCT OBSTRUCTION	2
BIFASCICULAR BLOCK	2
Bicuspid aortic valve	2
BACTERIAL INFECTION	2
Atrioventricular septal defect	2
ATRIOVENTRICULAR DISSOCIATION	2
Atrial hypertrophy	2
ASPIRATION PLEURAL CAVITY	2
ARTERIOVENOUS FISTULA OCCLUSION	2
ARTERIAL STENOSIS LIMB	2
ARTERIAL RESTENOSIS	2
APLASTIC ANAEMIA	2
APALLIC SYNDROME	2
Aortic occlusion	2
AORTIC DISORDER	2
AORTIC ANEURYSM RUPTURE	2
AORTIC ANEURYSM REPAIR	2
ANORECTAL DISORDER	2
ANAEMIA OF CHRONIC DISEASE	2
ANAEMIA MEGALOBLASTIC	2
ADRENAL NEOPLASM	2
ABNORMAL FAECES	2
ABNORMAL BEHAVIOUR	2
ABDOMINAL HERNIA	2
Xanthelasma	1
WRONG TECHNIQUE IN DRUG USAGE PROCESS	1
WRONG DRUG ADMINISTERED	1
Wound secretion	1
White matter lesion	1
WARM TYPE HAEMOLYTIC ANAEMIA	1
WALLENBERG SYNDROME	1
WALKING AID USER	1
WAIST CIRCUMFERENCE INCREASED	1
VOLVULUS	1
Vocal cord disorder	1
Vitreous degeneration	1
VITAMIN D DECREASED	1
VIRAL TRACHEITIS	1
Viral pericarditis	1
Viral cardiomyopathy	1
VICTIM OF ELDER ABUSE	1
VESTIBULAR NEURONITIS	1
Vertigo positional	1
Vertebral artery dissection	1
VENTRICULAR REMODELING	1
VENTRICULAR INTERNAL DIAMETER ABNORMAL	1
Ventricular hyperkinesia	1
VENTRICULAR DYSKINESIA	1
VENTRICULAR ASSIST DEVICE INSERTION	1
Vena cava filter insertion	1
VASOSPASM	1
VASODILATATION	1
Vasoconstriction	1
VASCULITIC RASH	1
Vascular rupture	1
VASCULAR PURPURA	1
Vascular operation	1
VASCULAR BYPASS GRAFT	1
Vascular bypass dysfunction	1
UROGENITAL DISORDER	1
URINE ABNORMALITY	1
URINARY TRACT INFECTION FUNGAL	1
URINARY TRACT DISORDER	1
Urethral pain	1
Ureteral disorder	1
UNIVENTRICULAR HEART	1
UMBILICAL HERNIA	1
TYPHOID FEVER	1
TYPE III IMMUNE COMPLEX MEDIATED REACTION	1
TWIN PREGNANCY	1
TUNNEL VISION	1
Tumour excision	1
TROPONIN T INCREASED	1
TROPONIN	1
Trifascicular block	1
Tricuspid valve replacement	1
TRAUMATIC RENAL INJURY	1
Traumatic intracranial haemorrhage	1
Transverse sinus thrombosis	1
Transplant	1
TRANSFERRIN SATURATION INCREASED	1
TRANSFERRIN INCREASED	1
TRACHEOBRONCHITIS	1
Tracheal obstruction	1
Tracheal haemorrhage	1
TRACHEAL DISORDER	1
Toxic epidermal necrolysis	1
TOXIC ENCEPHALOPATHY	1
TOTAL CHOLESTEROL/HDL RATIO INCREASED	1
TOOTHACHE	1
TOOTH DISORDER	1
TONGUE OEDEMA	1
TONGUE HAEMATOMA	1
TOE DEFORMITY	1
TOBACCO USER	1
Tobacco abuse	1
TINEA PEDIS	1
Thyroidectomy	1
THYROID FUNCTION TEST ABNORMAL	1
THYROID CYST	1
THYROID CANCER	1
THYROID ADENOMA	1
Thrombotic cerebral infarction	1
THROMBOPHLEBITIS SUPERFICIAL	1
Thoracostomy	1
THORACIC VERTEBRAL FRACTURE	1
THORACIC CAVITY DRAINAGE	1
THINKING ABNORMAL	1
THALASSAEMIA BETA	1
THALASSAEMIA	1
Testicular swelling	1
TESTICULAR PAIN	1
TENSION	1
TENDONITIS	1
TEMPERATURE INTOLERANCE	1
TELANGIECTASIA	1
TARDIVE DYSKINESIA	1
Tachycardia paroxysmal	1
T-CELL LYMPHOMA	1
SYSTEMIC LUPUS ERYTHEMATOSUS	1
Synovial cyst	1
SURGICAL PROCEDURE REPEATED	1
Superior vena cava syndrome	1
Superior sagittal sinus thrombosis	1
SUFFOCATION FEELING	1
SUBCUTANEOUS NODULE	1
SUBCUTANEOUS EMPHYSEMA	1
Subclavian steal syndrome	1
STUPOR	1
Stroke in evolution	1
STOMATITIS	1
STILLBIRTH	1
Steroid therapy	1
STENT OCCLUSION	1
Stent malfunction	1
Stenosis	1
Steal syndrome	1
STAPHYLOCOCCUS TEST POSITIVE	1
STAPHYLOCOCCAL BACTERAEMIA	1
Squamous cell carcinoma of lung	1
SPUTUM CULTURE POSITIVE	1
SPLENORENAL SHUNT	1
SPLENIC VEIN THROMBOSIS	1
SPLENIC INFARCTION	1
Splenic artery aneurysm	1
SPLENECTOMY	1
SPLEEN DISORDER	1
SPIROMETRY ABNORMAL	1
Spinal cord infection	1
Spinal cord infarction	1
Speech rehabilitation	1
SOFT TISSUE INJURY	1
SOFT TISSUE DISORDER	1
SOCIAL AVOIDANT BEHAVIOUR	1
SNEEZING	1
SMALL INTESTINE ULCER	1
SMALL INTESTINAL HAEMORRHAGE	1
Small cell lung cancer metastatic	1
SLUGGISHNESS	1
Slow speech	1
SKIN REACTION	1
SKIN NEOPLASM EXCISION	1
SKIN LACERATION	1
SKIN CHAPPED	1
SKIN BURNING SENSATION	1
Skin atrophy	1
SJOGREN'S SYNDROME	1
SINUS HEADACHE	1
SIMPLE PARTIAL SEIZURES	1
SIDEROBLASTIC ANAEMIA	1
SICKLE CELL ANAEMIA WITH CRISIS	1
SHUNT OCCLUSION	1
SHOCK HAEMORRHAGIC	1
SEVERE ACUTE RESPIRATORY SYNDROME	1
SERUM FERRITIN INCREASED	1
SENSATION OF HEAVINESS	1
Senile dementia	1
SELF ESTEEM DECREASED	1
Scrotal swelling	1
SCROTAL OEDEMA	1
SCROTAL INFECTION	1
SCLERODERMA	1
SCIATICA	1
SCHIZOPHRENIA	1
SCAN MYOCARDIAL PERFUSION ABNORMAL	1
Sarcoidosis	1
SALIVARY GLAND CALCULUS	1
Ruptured cerebral aneurysm	1
ROTATOR CUFF SYNDROME	1
Rotator cuff repair	1
RHONCHI	1
RHABDOMYOSARCOMA	1
RETROPERITONEAL HAEMATOMA	1
RETINITIS	1
RETINAL VEIN THROMBOSIS	1
RETINAL PIGMENTATION	1
Retinal infarction	1
Retinal degeneration	1
RETINAL CYST	1
RETINAL ARTERY THROMBOSIS	1
RESTRICTIVE PULMONARY DISEASE	1
RESTRICTIVE CARDIOMYOPATHY	1
Respiratory rate increased	1
RESPIRATORY ALKALOSIS	1
RESPIRATION ABNORMAL	1
RESORPTION BONE INCREASED	1
REPERFUSION INJURY	1
Reocclusion	1
RENAL TUBULAR ACIDOSIS	1
RENAL NEOPLASM	1
RENAL MASS	1
Renal haematoma	1
Renal cancer metastatic	1
Renal artery occlusion	1
RENAL ARTERY ARTERIOSCLEROSIS	1
REFRACTION DISORDER	1
RED BLOOD CELL COUNT INCREASED	1
RECTAL POLYP	1
RECTAL FISSURE	1
READING DISORDER	1
RASH PUSTULAR	1
RASH PAPULAR	1
RASH MACULO-PAPULAR	1
RASH MACULAR	1
RASH ERYTHEMATOUS	1
RADIAL NERVE PALSY	1
PUSTULAR PSORIASIS	1
PURPURA	1
PUPILLARY REFLEX IMPAIRED	1
PUPIL FIXED	1
PULSE ABNORMAL	1
Pulmonary valve disease	1
Pulmonary sepsis	1
PULMONARY MYCOSIS	1
PULMONARY ARTERY THROMBOSIS	1
PULMONARY ARTERIOPATHY	1
PULMONARY ALVEOLAR HAEMORRHAGE	1
PUBIS FRACTURE	1
Pseudomonas infection	1
PROTHROMBIN TIME SHORTENED	1
PROTEIN URINE PRESENT	1
PROTEIN TOTAL INCREASED	1
PROTEIN S DEFICIENCY	1
PROSTATITIS	1
PROSTATIC HAEMORRHAGE	1
PROSTATIC ADENOMA	1
PRODUCT CONTAMINATION	1
PRESCRIBED OVERDOSE	1
PRE-EXISTING CONDITION IMPROVED	1
POSTOPERATIVE WOUND INFECTION	1
Post procedural stroke	1
POST PROCEDURAL INFECTION	1
POST PROCEDURAL HAEMORRHAGE	1
PORIOMANIA	1
POLYDIPSIA	1
PO2 DECREASED	1
PNEUMONIA PNEUMOCOCCAL	1
Pneumonia haemophilus	1
Pneumonia fungal	1
PNEUMOCYSTIS CARINII PNEUMONIA	1
Pleuropericarditis	1
PLEURAL FIBROSIS	1
PLASTIC SURGERY	1
PITUITARY TUMOUR BENIGN	1
PHOSPHORUS METABOLISM DISORDER	1
PHARYNX DISCOMFORT	1
PHARYNGITIS STREPTOCOCCAL	1
PHARYNGITIS	1
Petit mal epilepsy	1
PERNICIOUS ANAEMIA	1
PERIVENTRICULAR LEUKOMALACIA	1
PERIPHERAL SENSORY NEUROPATHY	1
PERIORBITAL OEDEMA	1
Pericarditis uraemic	1
Pericardiotomy	1
PERIARTHRITIS	1
Peptic ulcer	1
Penile prosthesis insertion	1
PELVIC PAIN	1
PEAK EXPIRATORY FLOW RATE ABNORMAL	1
PCO2 DECREASED	1
Partial seizures	1
Parathyroid tumour benign	1
Paraparesis	1
PARADOXICAL DRUG REACTION	1
PAPILLITIS	1
PAPILLARY TUMOUR OF RENAL PELVIS	1
PANNICULITIS	1
PANCREATITIS RELAPSING	1
PANCREATIC PSEUDOCYST	1
PANCREATIC INJURY	1
PANCREATIC CYST	1
OXYGEN SATURATION ABNORMAL	1
OVARIAN CANCER	1
OSTEOPOROTIC FRACTURE	1
OSTEOMALACIA	1
Osteitis deformans	1
OROPHARYNGEAL PAIN	1
ORAL MUCOSAL EXFOLIATION	1
OPTIC NEURITIS	1
OPTIC NERVE INJURY	1
OPTIC NERVE DISORDER	1
OPERATIVE HAEMORRHAGE	1
Open fracture	1
OESOPHAGITIS ULCERATIVE	1
OESOPHAGEAL STENOSIS	1
OESOPHAGEAL RUPTURE	1
OESOPHAGEAL DILATATION	1
Oesophageal adenocarcinoma	1
OEDEMA MOUTH	1
OBSTRUCTIVE UROPATHY	1
Obesity surgery	1
NORMAL TENSION GLAUCOMA	1
NONSPECIFIC REACTION	1
NON-SMALL CELL LUNG CANCER	1
NON-HODGKIN'S LYMPHOMA RECURRENT	1
Non-alcoholic steatohepatitis	1
NODULE	1
NODDING OF HEAD	1
NO ADVERSE EFFECT	1
NIPPLE PAIN	1
NEUTROPHIL COUNT INCREASED	1
NEUTROPHIL COUNT DECREASED	1
NEUROMA	1
Neurogenic bladder	1
NERVE ROOT LESION	1
NEPHROGENIC ANAEMIA	1
Neovascularisation	1
NEOPLASM SKIN	1
NEOPLASM PROGRESSION	1
NEOPLASM GROWTH ACCELERATED	1
NECK INJURY	1
NECK DEFORMITY	1
NASAL CYST	1
NAIL BED BLEEDING	1
NAIL AVULSION	1
MYOSITIS	1
MYODESOPSIA	1
Myoclonus	1
Myocardial stunning	1
Myocardial necrosis	1
MYOCARDIAL HAEMORRHAGE	1
MYELOFIBROSIS	1
Myelitis transverse	1
MYASTHENIA GRAVIS	1
Muscle twitching	1
MUSCLE STRAIN	1
MUSCLE HAEMORRHAGE	1
MUSCLE CRAMP	1
MUSCLE CONTRACTURE	1
MUSCLE CONTRACTIONS INVOLUNTARY	1
Multiple sclerosis relapse	1
Multiple organ dysfunction syndrome	1
MULTIPLE MYELOMA	1
MULTIPLE DRUG OVERDOSE	1
MULTIPLE CONGENITAL ABNORMALITIES	1
Multi-organ disorder	1
MUCOCUTANEOUS CANDIDIASIS	1
MOUTH ULCERATION	1
MOTOR NEURONE DISEASE	1
Monoparesis	1
Mononeuritis	1
MONOCYTOSIS	1
MONOCYTE COUNT INCREASED	1
MONOCLONAL GAMMOPATHY	1
MOANING	1
Mitral valve disease mixed	1
MIOSIS	1
MIGRAINE WITH AURA	1
Microvascular coronary artery disease	1
MICROCYTOSIS	1
Microalbuminuria	1
METATARSALGIA	1
METASTATIC RENAL CELL CARCINOMA	1
METASTATIC NEOPLASM	1
METASTASES TO PERITONEUM	1
METASTASES TO LUNG	1
METABOLIC SYNDROME	1
Metabolic encephalopathy	1
METABOLIC ALKALOSIS	1
Mesothelioma	1
MENORRHAGIA	1
Meniscus injury	1
MENINGORRHAGIA	1
MEGAKARYOCYTES INCREASED	1
MEGAKARYOCYTES	1
MEDICATION RESIDUE	1
MEDICAL DEVICE PAIN	1
MEAN CELL HAEMOGLOBIN DECREASED	1
MEAN CELL HAEMOGLOBIN CONCENTRATION DECREASED	1
MATERNAL EXPOSURE DURING PREGNANCY	1
MASTOIDITIS	1
MASTECTOMY	1
MASS	1
MARITAL PROBLEM	1
MANIA	1
MALNUTRITION	1
MALLORY-WEISS SYNDROME	1
MALIGNANT RENAL HYPERTENSION	1
Macular scar	1
MACULAR ISCHAEMIA	1
MACULAR HOLE	1
LYMPHOPROLIFERATIVE DISORDER	1
LYMPHOCYTOSIS	1
LYMPHOCYTIC INFILTRATION	1
LYMPHOCYTE COUNT INCREASED	1
LYMPHATIC SYSTEM NEOPLASM	1
LYMPHADENITIS	1
LUNG SQUAMOUS CELL CARCINOMA STAGE UNSPECIFIED	1
LUNG INFECTION PSEUDOMONAL	1
LUNG INFECTION	1
LUNG HYPERINFLATION	1
LUNG CREPITATION	1
Lung carcinoma cell type unspecified stage IV	1
LUMBAR VERTEBRAL FRACTURE	1
LUMBAR SPINAL STENOSIS	1
LOCAL REACTION	1
LIVER OPERATION	1
Liver function test increased	1
LISTLESS	1
LIPIDS	1
LIP OEDEMA	1
LIP DRY	1
Lip and/or oral cavity cancer	1
Limb operation	1
Limb amputation	1
LICHEN PLANUS	1
LEUKOCYTOCLASTIC VASCULITIS	1
LEUKAEMIA	1
LEPTOSPIROSIS	1
LENTICULAR OPACITIES	1
Lens dislocation	1
LEGIONELLA INFECTION	1
Left ventricular enlargement	1
LEFT VENTRICULAR END-DIASTOLIC PRESSURE INCREASED	1
LARGE INTESTINE PERFORATION	1
Lagophthalmos	1
LACRIMAL DISORDER	1
LABORATORY TEST INTERFERENCE	1
Laboratory test abnormal	1
LABILE HYPERTENSION	1
Labelled drug-drug interaction medication error	1
Kyphoscoliotic heart disease	1
Jugular vein thrombosis	1
JOINT RANGE OF MOTION DECREASED	1
Joint lock	1
Ischaemic neuropathy	1
Ischaemic mitral regurgitation	1
IRON BINDING CAPACITY TOTAL INCREASED	1
IRON BINDING CAPACITY TOTAL ABNORMAL	1
IRITIS	1
Investigation	1
INTRAOCULAR LENS IMPLANT	1
INTRANASAL HYPOAESTHESIA	1
Intraductal proliferative breast lesion	1
INTRACRANIAL PRESSURE INCREASED	1
Intracranial haematoma	1
Intra-aortic balloon placement	1
Intestinal perforation	1
INTESTINAL OPERATION	1
Intestinal infarction	1
INTESTINAL FISTULA	1
INTESTINAL DILATATION	1
INTERVERTEBRAL DISCITIS	1
INTERVERTEBRAL DISC PROTRUSION	1
INTERVERTEBRAL DISC DISPLACEMENT	1
INTERVERTEBRAL DISC DISORDER	1
INTERVERTEBRAL DISC COMPRESSION	1
Internal fixation of fracture	1
INTERCAPILLARY GLOMERULOSCLEROSIS	1
INTENTIONAL MISUSE	1
Insulin-requiring type 2 diabetes mellitus	1
INNER EAR DISORDER	1
INJECTION SITE URTICARIA	1
INFLUENZA	1
INFECTIVE EXACERBATION OF CHRONIC OBSTRUCTIVE AIRWAYS DISEASE	1
INFECTIOUS PERITONITIS	1
INFECTION IN AN IMMUNOCOMPROMISED HOST	1
INFECTED SKIN ULCER	1
INDURATION	1
INCREASED VISCOSITY OF BRONCHIAL SECRETION	1
INCOHERENT	1
INCISION SITE PAIN	1
Inappropriate schedule of drug administration	1
IN-STENT ARTERIAL RESTENOSIS	1
Implantable defibrillator replacement	1
Implant site pain	1
IMMUNOSUPPRESSION	1
IMMUNOGLOBULINS INCREASED	1
IMMUNODEFICIENCY	1
Immune-mediated necrotising myopathy	1
Illusion	1
ILLITERACY	1
ILIAC ARTERY THROMBOSIS	1
ILIAC ARTERY OCCLUSION	1
IDIOPATHIC PULMONARY FIBROSIS	1
HYSTERECTOMY	1
Hypovolaemic shock	1
HYPOVENTILATION	1
HYPOTHERMIA	1
Hyporeflexia	1
HYPOPROTEINAEMIA	1
HYPOPERFUSION	1
HYPOMANIA	1
HYPOLIPIDAEMIA	1
HYPOKALAEMIC SYNDROME	1
HYPOCALCAEMIA	1
HYPOALBUMINAEMIA	1
HYPERTONIA	1
HYPERTENSIVE CARDIOMEGALY	1
HYPERPLASIA	1
HYPERPARATHYROIDISM	1
HYPERMETROPIA	1
HYPERKINESIA	1
HYPERGAMMAGLOBULINAEMIA	1
HYPERDYNAMIC LEFT VENTRICLE	1
HYPERCHROMASIA	1
HYPERCHLORHYDRIA	1
HYPERBILIRUBINAEMIA	1
HYPERAMMONAEMIA	1
HYPERALBUMINAEMIA	1
HYDROCELE	1
HYDRAEMIA	1
Hospice care	1
HORNER'S SYNDROME	1
Hordeolum	1
HERPES ZOSTER	1
Hepatocellular carcinoma	1
Hepatobiliary cancer	1
HEPATITIS INFECTIOUS	1
HEPATITIS CHRONIC ACTIVE	1
HEPATITIS A ANTIBODY POSITIVE	1
HEPATIC ISCHAEMIA	1
Hepatic infection	1
HEPATIC HAEMORRHAGE	1
HEPATIC CYST	1
Hepatic cancer metastatic	1
HEPARIN-INDUCED THROMBOCYTOPENIA	1
HENOCH-SCHONLEIN PURPURA	1
HEMIANOPIA	1
HELICOBACTER PYLORI IDENTIFICATION TEST POSITIVE	1
HELICOBACTER INFECTION	1
Heat stroke	1
HEART SOUNDS ABNORMAL	1
HANGOVER	1
HAIR TEXTURE ABNORMAL	1
HAIR COLOUR CHANGES	1
HAEMORRHOID OPERATION	1
Haemophilus sepsis	1
HAEMOPHILUS INFECTION	1
HAEMOGLOBIN ABNORMAL	1
HAEMODYNAMIC INSTABILITY	1
HAEMATOCRIT ABNORMAL	1
HAEMANGIOMA OF LIVER	1
HAEMANGIOMA	1
Graft thrombosis	1
Graft dysfunction	1
Gouty arthritis	1
GLYCOSURIA	1
Glomerulosclerosis	1
GLOMERULAR VASCULAR DISORDER	1
GLOBULINS INCREASED	1
GLOBULINS DECREASED	1
GLIOSIS	1
Glioblastoma	1
GINGIVAL SWELLING	1
GENITAL DISORDER FEMALE	1
Generalised anxiety disorder	1
GENERAL PHYSICAL CONDITION ABNORMAL	1
Gastrointestinal tube insertion	1
GASTROINTESTINAL EROSION	1
GASTROINTESTINAL CARCINOMA	1
GASTROENTERITIS	1
GASTRITIS HAEMORRHAGIC	1
GASTRIC VARICES	1
GASTRIC ULCER HAEMORRHAGE	1
GASTRIC OPERATION	1
GAMMOPATHY	1
GALLBLADDER POLYP	1
FUNGAL INFECTION	1
Fungal endocarditis	1
FULL BLOOD COUNT ABNORMAL	1
Frequent bowel movements	1
FRACTURED SACRUM	1
FOREARM FRACTURE	1
FOOT AMPUTATION	1
FOOD CRAVING	1
FOLATE DEFICIENCY	1
FOETAL MALFORMATION	1
Flushing	1
FISTULA	1
FILARIASIS	1
FIBROSIS	1
FEELING JITTERY	1
FAT NECROSIS	1
Familial tremor	1
FALLOT'S TETRALOGY	1
FAECES HARD	1
FABRY'S DISEASE	1
EYELID INFECTION	1
EYE ROLLING	1
EYE REDNESS	1
EYE OPERATION	1
EYE MOVEMENT DISORDER	1
EYE EXCISION	1
EYE DISCHARGE	1
EXTREMITY NECROSIS	1
EXPIRED DRUG ADMINISTERED	1
EXOPHTHALMOS	1
ESCHERICHIA TEST POSITIVE	1
ESCHERICHIA SEPSIS	1
ESCHERICHIA INFECTION	1
ERYTHROPOIESIS ABNORMAL	1
ERYSIPELAS	1
ERUCTATION	1
EROSIVE OESOPHAGITIS	1
EOSINOPHILIA	1
ENZYME ABNORMALITY	1
Enterococcal sepsis	1
Enterococcal infection	1
Enterococcal bacteraemia	1
Endotracheal intubation	1
Endosalpingiosis	1
ENDOMETRIAL CANCER	1
ENDOCARDITIS VIRAL	1
Endocardial disease	1
Endarterectomy	1
End stage renal disease	1
ENCHONDROMA	1
ENCEPHALITIS HERPES	1
EMPYEMA	1
Emergency care examination	1
Electroencephalogram abnormal	1
ELECTROCARDIOGRAM T WAVE AMPLITUDE DECREASED	1
Electrocardiogram ST segment	1
ELECTROCARDIOGRAM QRS COMPLEX ABNORMAL	1
ELECTROCARDIOGRAM Q WAVE ABNORMAL	1
ELECTROCARDIOGRAM LOW VOLTAGE	1
ELBOW DEFORMITY	1
EAR DISORDER	1
DYSTONIA	1
DYSMORPHISM	1
Dysgraphia	1
DUODENITIS	1
DUODENAL ULCER HAEMORRHAGE	1
DRUG-INDUCED LIVER INJURY	1
DRUG RESISTANCE	1
DRUG INTOLERANCE	1
DRUG ERUPTION	1
DRUG ABUSE	1
DROOLING	1
Dissociative identity disorder	1
DISORDER OF ORBIT	1
DIABETIC VASCULAR DISORDER	1
DIABETIC ULCER	1
DIABETIC HYPERGLYCAEMIC COMA	1
DIABETES WITH HYPEROSMOLARITY	1
DIABETES MELLITUS INSULIN-DEPENDENT	1
DEVICE RELATED SEPSIS	1
Device failure	1
Dermatitis exfoliative	1
DERMATITIS	1
DEPENDENCE ON RESPIRATOR	1
DENTAL CARIES	1
DEMYELINATION	1
DEMYELINATING POLYNEUROPATHY	1
DELUSION	1
DEATH OF COMPANION	1
DEAFNESS NEUROSENSORY	1
DEAFNESS BILATERAL	1
CYTOLOGY ABNORMAL	1
CYSTITIS KLEBSIELLA	1
CYSTITIS HAEMORRHAGIC	1
CROHN'S DISEASE	1
CREST SYNDROME	1
CREATININE RENAL CLEARANCE DECREASED	1
CRANIOCEREBRAL INJURY	1
Cranial nerve paralysis	1
COX-MAZE PROCEDURE	1
CORTICAL LAMINAR NECROSIS	1
Coronary revascularisation	1
CORONARY ENDARTERECTOMY	1
CORONARY ARTERY PERFORATION	1
CORONARY ARTERY DILATATION	1
CORNEAL STRIAE	1
CORNEAL OPACITY	1
Corneal oedema	1
Corneal disorder	1
COOMBS NEGATIVE HAEMOLYTIC ANAEMIA	1
CONVERSION DISORDER	1
CONTRAST MEDIA REACTION	1
CONTRAINDICATION TO MEDICAL TREATMENT	1
CONJUNCTIVITIS ALLERGIC	1
CONJUNCTIVAL DISCOLOURATION	1
CONJUNCTIVAL CYST	1
CONGENITAL NAIL DISORDER	1
CONGENITAL ANOMALY	1
CONCOMITANT DISEASE PROGRESSION	1
COMPUTERISED TOMOGRAM HEAD	1
COMPLICATED MIGRAINE	1
COMMINUTED FRACTURE	1
COMA HEPATIC	1
COMA ACIDOTIC	1
COLOUR BLINDNESS	1
Colorectal cancer metastatic	1
COLONIC STENOSIS	1
COLONIC HAEMATOMA	1
COLLAPSE OF LUNG	1
COLITIS ULCERATIVE	1
COLITIS MICROSCOPIC	1
COLITIS	1
Coeliac artery stenosis	1
CLOSTRIDIUM DIFFICILE SEPSIS	1
CLOSTRIDIAL INFECTION	1
CLEFT LIP	1
CIRRHOSIS ALCOHOLIC	1
Chronic myelomonocytic leukaemia	1
CHRONIC HEPATITIS	1
CHOROIDITIS	1
Choroidal infarction	1
CHONDROMATOSIS	1
CHONDROCALCINOSIS PYROPHOSPHATE	1
CHONDROCALCINOSIS	1
CHOLANGITIS SCLEROSING	1
CHEST INJURY	1
CERVICOBRACHIAL SYNDROME	1
CERVICAL VERTEBRAL FRACTURE	1
Cervical myelopathy	1
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy	1
Cerebral artery thrombosis	1
CEREBRAL ARTERY EMBOLISM	1
Cerebral amyloid angiopathy	1
Cerebellar syndrome	1
CENTRAL PAIN SYNDROME	1
Central nervous system haemorrhage	1
Cellulitis staphylococcal	1
Cataract nuclear	1
Carotid artery dissection	1
Cardiac valve vegetation	1
CARDIAC SEPTAL DEFECT	1
Cardiac resynchronisation therapy	1
Cardiac perforation	1
Cardiac output	1
Cardiac myxoma	1
CARDIAC MONITORING	1
CARDIAC IMAGING PROCEDURE ABNORMAL	1
CARDIAC FIBRILLATION	1
Cardiac dysfunction	1
Cardiac discomfort	1
CARDIAC ASTHMA	1
CAPILLARY DISORDER	1
CALCIUM DEFICIENCY	1
CALCIPHYLAXIS	1
CALCINOSIS	1
CAESAREAN SECTION	1
BURNS SECOND DEGREE	1
BRUGADA SYNDROME	1
BRONCHIOLITIS	1
Bronchial obstruction	1
BRONCHIAL DISORDER	1
Breath odour	1
BREAST TENDERNESS	1
Breast swelling	1
BREAST OEDEMA	1
BREAST ENLARGEMENT	1
BREAST CANCER RECURRENT	1
BREAST CANCER FEMALE	1
BRAIN NEOPLASM MALIGNANT	1
BRAIN NATRIURETIC PEPTIDE DECREASED	1
BRAIN CANCER METASTATIC	1
BRADYPHRENIA	1
BRADYKINESIA	1
Bowen's disease	1
BORDERLINE GLAUCOMA	1
BONE SARCOMA	1
BONE MARROW OEDEMA SYNDROME	1
BONE MARROW OEDEMA	1
BONE INFARCTION	1
BONE GRAFT	1
BONE FISSURE	1
Bone cancer	1
BLUE TOE SYNDROME	1
BLOOD THYROID STIMULATING HORMONE INCREASED	1
BLOOD TEST ABNORMAL	1
BLOOD SODIUM INCREASED	1
BLOOD PRESSURE IMMEASURABLE	1
BLOOD PH INCREASED	1
Blood parathyroid hormone increased	1
BLOOD LACTIC ACID INCREASED	1
BLOOD IMMUNOGLOBULIN M INCREASED	1
BLOOD IMMUNOGLOBULIN G INCREASED	1
BLOOD HOMOCYSTEINE INCREASED	1
BLOOD ELECTROLYTES ABNORMAL	1
BLOOD CREATININE ABNORMAL	1
BLOOD CREATINE PHOSPHOKINASE	1
BLOOD CREATINE INCREASED	1
Blood cholesterol	1
BLOOD CHLORIDE INCREASED	1
BLOOD CALCIUM INCREASED	1
BLOOD ALCOHOL INCREASED	1
Bladder cancer recurrent	1
BILIARY TRACT DISORDER	1
BILIARY NEOPLASM	1
Bile duct cancer	1
BENIGN HYDATIDIFORM MOLE	1
Basedow's disease	1
BASE EXCESS POSITIVE	1
BACK CRUSHING	1
Autonomic neuropathy	1
AUTOIMMUNE HEPATITIS	1
Auditory disorder	1
ATOPY	1
ASTROCYTOMA	1
ASTIGMATISM	1
ASTHENOPIA	1
Aspartate aminotransferase abnormal	1
ASBESTOSIS	1
ARTHRITIS BACTERIAL	1
ARTERY DISSECTION	1
ARTERIOVENOUS GRAFT SITE INFECTION	1
ARTERIOPATHIC DISEASE	1
ARTERIOGRAM CORONARY ABNORMAL	1
ARTERIAL THROMBOSIS	1
Apraxia	1
APPENDICITIS	1
APPARENT LIFE THREATENING EVENT	1
APOLIPOPROTEIN A-II DECREASED	1
Aphagia	1
Aortic valve disease mixed	1
AORTIC THROMBOSIS	1
Aortic rupture	1
Aortic injury	1
AORTIC ELONGATION	1
AORTIC ATHEROSCLEROSIS	1
ANURIA	1
ANTINUCLEAR ANTIBODY INCREASED	1
ANOVULATORY CYCLE	1
ANOSMIA	1
ANION GAP INCREASED	1
Angiogram peripheral	1
Angiogram abnormal	1
Angiocardiogram	1
ANEURYSM RUPTURED	1
Anaphylactoid reaction	1
ANAL FISSURE	1
ANAEMIA POSTOPERATIVE	1
AMYOTROPHIC LATERAL SCLEROSIS	1
AMYLOIDOSIS	1
AMMONIA INCREASED	1
Ammonia abnormal	1
Ammonia	1
Amblyopia	1
AMAUROSIS FUGAX	1
ALVEOLITIS FIBROSING	1
ALPHA 2 GLOBULIN INCREASED	1
ALKALOSIS	1
ALCOHOL ABUSE	1
ALBUMIN URINE PRESENT	1
AGRANULOCYTOSIS	1
ADVERSE REACTION	1
ADRENAL MASS	1
ADRENAL CORTEX NECROSIS	1
Adenocarcinoma gastric	1
ADENOCARCINOMA	1
Addison's disease	1
Adams-Stokes syndrome	1
Acute prerenal failure	1
Acute myeloid leukaemia	1
Acute endocarditis	1
Acute cardiac event	1
ACRODERMATITIS	1
ACQUIRED DIAPHRAGMATIC EVENTRATION	1
Accidental poisoning	1
ACCIDENT	1
ACCELERATED IDIOVENTRICULAR RHYTHM	1
ACANTHOSIS	1
ABSCESS LIMB	1
ABSCESS	1
ABNORMAL CLOTTING FACTOR	1
ABNORMAL CHEST SOUND	1
ABDOMINAL TENDERNESS	1

Filtered ChEMBL targets:

Target UniProtKB ID	Activity in nm	Target Name	Target gene
O95342	6400	Bile salt export pump	ABCBB_HUMAN
P00918	4069	Carbonic anhydrase 2	CAH2_HUMAN
P02545	2.2	Prelamin-A/C	LMNA_HUMAN
P24557	3560	Thromboxane-A synthase	THAS_HUMAN
P27338	832	Amine oxidase [flavin-containing] B	AOFB_HUMAN
P37231	1	Peroxisome proliferator-activated receptor gamma	PPARG_HUMAN
Q03181	8890	Peroxisome proliferator-activated receptor delta	PPARD_HUMAN
Q07869	4	Peroxisome proliferator-activated receptor alpha	PPARA_HUMAN
Q14973	5100	Sodium/bile acid cotransporter	NTCP_HUMAN
Q8N5K1	2290
Q9NZ45	31	CDGSH iron-sulfur domain-containing protein 1	CISD1_HUMAN

Toxicity information:

Toxicity type:	cardiovascular

External links:

ChEBML:	CHEMBL121
DrugBank:	DB00412