Withdrawn ID: | w13 |
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Canonical SMILES: | |
Standard InChI: | |
Standard InChIKey: | |
ATC class(es): | N06BX05 |
Molecular Formula: | C20H21ClN2O4 |
Molweight: | 388.845 |
Withdrawn due to drug safety reasons: | Yes |
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First approved: | 1983 |
First death: | 1992 |
First withdrawn: | 1991 |
Last withdrawn: | 1991 |
Reference: | https://www.ncbi.nlm.nih.gov/pubmed/1506632 |
Target UniProtKB ID | Activity in nm | Target Name | Target gene |
---|---|---|---|
P02545 | 10000 | Prelamin-A/C | LMNA_HUMAN |
Q16665 | 3981.1 | Hypoxia-inducible factor 1-alpha | HIF1A_HUMAN |
Toxicity class: | 5 |
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Toxicity type: | hepatic |
LD50: | 4150 mg/kg |
ChEBML: | CHEMBL254857 |
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DrugBank: |