Danthron
General information:
| Withdrawn ID: | w108 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | A06AB53 |
| Molecular Formula: | C14H8O4 |
| Molweight: | 240.211 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | Yes |
|---|---|
| First approved: | 1900 |
| First withdrawn: | 1963 |
| Last withdrawn: | 1988 |
| Reference: | https://www.ncbi.nlm.nih.gov/pubmed/1900101 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| P02545 | 10000 | Prelamin-A/C | LMNA_HUMAN |
| P10636 | 5011.9 | Microtubule-associated protein tau | TAU_HUMAN |
| P16473 | 1995.3 | Thyrotropin receptor | TSHR_HUMAN |
| P28482 | 3162.3 | Mitogen-activated protein kinase 1 | MK01_HUMAN |
Toxicity information:
| Toxicity class: | 5 |
|---|---|
| Toxicity type: | carcinogenicity |
| LD50: | 5000 mg/kg |
External links:
| ChEBML: | CHEMBL53418 |
|---|---|
| DrugBank: | DB04816 |