cinacalcet


EMA7



General information:


Withdrawn ID: EMA7
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es): H05BX01
Molecular Formula: C22H22F3N
Molweight: 357.412



Withdrawal information:


Withdrawn due to drug safety reasons:No



Side-effects:

Total reported cases (submitted by medical professionals) with cinacalcet as primary suspect: 28636


Reported final outcomes:
Hospitalization (initial or prolonged): 6863
Death: 1223
Life-Threatening condition: 173
Disability: 159
Intervention required to prevent permanent impairment/damage: 4
Congenital anomaly: 3


Reported side-effects:

Side-effect Case number
DRUG DOSE OMISSION6615
HOSPITALISATION4743
Laboratory test abnormal3279
NAUSEA1424
ADVERSE DRUG REACTION1165
DEATH997
VOMITING967
Intentional product misuse944
MALAISE790
DIARRHOEA685
DECREASED APPETITE577
ABDOMINAL DISCOMFORT475
MUSCLE SPASMS471
UNEVALUABLE EVENT407
Off label use386
ADVERSE EVENT378
BLOOD PARATHYROID HORMONE INCREASED371
ABDOMINAL PAIN UPPER337
DRUG INEFFECTIVE329
DIZZINESS321
HYPOTENSION306
HYPOPHAGIA248
BLOOD CALCIUM DECREASED246
HYPOCALCAEMIA229
PARAESTHESIA224
Hospice care213
CONSTIPATION211
PRURITUS210
HEADACHE200
FATIGUE196
DYSPHAGIA190
BLOOD PARATHYROID HORMONE ABNORMAL186
PNEUMONIA185
GASTROINTESTINAL DISORDER169
BLOOD CALCIUM INCREASED166
DYSPNOEA165
Wrong technique in product usage process164
HYPOAESTHESIA149
CEREBROVASCULAR ACCIDENT145
HYPERTENSION141
BLOOD PARATHYROID HORMONE DECREASED138
SURGERY136
RASH134
ASTHENIA127
HYPERCALCAEMIA126
DRUG INTOLERANCE124
Seizure118
FALL118
PAIN108
MYOCARDIAL INFARCTION108
TRANSPLANT106
MYALGIA106
GASTROINTESTINAL TUBE INSERTION104
Rehabilitation therapy102
WEIGHT DECREASED94
Living in residential institution94
TREATMENT NONCOMPLIANCE89
PAIN IN EXTREMITY89
FEELING ABNORMAL89
ARRHYTHMIA89
GASTRIC DISORDER87
BLOOD CALCIUM ABNORMAL86
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION85
NASOPHARYNGITIS83
CHEST PAIN81
INFECTION79
CARDIAC DISORDER79
TREMOR77
DRUG INTERACTION77
ARTHRALGIA75
RENAL TRANSPLANT74
CONVULSION73
BLOOD PHOSPHORUS INCREASED72
PARATHYROIDECTOMY69
DYSPEPSIA67
ABDOMINAL PAIN67
SOMNOLENCE66
HYPERSENSITIVITY65
DIALYSIS64
BONE PAIN64
COUGH63
INSOMNIA62
DRUG HYPERSENSITIVITY59
BACK PAIN58
GASTROINTESTINAL HAEMORRHAGE56
CARDIAC FAILURE56
ALOPECIA56
SEPSIS53
Mastication disorder53
INCORRECT DOSE ADMINISTERED48
Gastrostomy48
BLOOD PRESSURE DECREASED48
CARDIAC ARREST47
WRONG TECHNIQUE IN DRUG USAGE PROCESS46
MUSCULAR WEAKNESS46
Drug effect incomplete46
CALCIPHYLAXIS46
DEPRESSION44
LOSS OF CONSCIOUSNESS43
HALLUCINATION43
Unevaluable investigation40
Peripheral swelling40
PALPITATIONS39
HEART RATE INCREASED38
GASTROOESOPHAGEAL REFLUX DISEASE38
ELECTROCARDIOGRAM QT PROLONGED38
ENTERAL NUTRITION37
WEIGHT INCREASED36
THROMBOSIS36
CONFUSIONAL STATE36
ANXIETY36
MEMORY IMPAIRMENT35
GAIT DISTURBANCE35
ATRIAL FIBRILLATION35
PARATHYROID TUMOUR BENIGN34
BLOOD PRESSURE INCREASED34
URTICARIA33
SYNCOPE33
BLOOD PRESSURE ABNORMAL33
URINARY TRACT INFECTION32
HAEMOGLOBIN DECREASED32
DEHYDRATION32
ABDOMINAL DISTENSION32
HYPERKALAEMIA31
Appetite disorder31
PULMONARY OEDEMA30
Therapy cessation29
PERITONITIS29
PANCREATITIS29
LETHARGY29
GENERAL PHYSICAL HEALTH DETERIORATION29
DIABETES MELLITUS29
CONDITION AGGRAVATED29
Therapy non-responder28
RENAL FAILURE28
HIP FRACTURE28
HAEMORRHAGE28
FLATULENCE28
ANAEMIA28
RESPIRATORY FAILURE27
MEDICATION ERROR27
DRY MOUTH27
CARDIAC OPERATION27
BLOOD PHOSPHORUS ABNORMAL27
Neoplasm malignant26
INFLUENZA26
PLEURAL EFFUSION25
OEDEMA PERIPHERAL25
MUSCLE TWITCHING25
SWELLING24
PYREXIA24
PARATHYROID DISORDER24
FLUID RETENTION24
FAECES DISCOLOURED24
DISCOMFORT24
CARDIAC FAILURE CONGESTIVE24
BRONCHITIS24
SWELLING FACE23
RENAL DISORDER23
VERTIGO22
SKIN ULCER22
RASH PRURITIC22
RASH GENERALISED22
LEG AMPUTATION22
CHEST DISCOMFORT22
BLOOD POTASSIUM INCREASED22
BLOOD PHOSPHORUS DECREASED22
BLOOD GLUCOSE DECREASED22
ACUTE MYOCARDIAL INFARCTION22
ABASIA22
VISION BLURRED21
THROMBOCYTOPENIA21
Musculoskeletal disorder21
HYPERHIDROSIS21
EATING DISORDER21
DEMENTIA21
THERAPEUTIC RESPONSE DECREASED20
MUSCULOSKELETAL PAIN20
FLUID OVERLOAD20
DYSGEUSIA20
CARDIOVASCULAR DISORDER20
TACHYCARDIA19
LOWER LIMB FRACTURE19
LOCALISED INFECTION19
Toe amputation18
Ill-defined disorder18
HUNGRY BONE SYNDROME18
HAEMODIALYSIS18
GASTRITIS18
BLOOD GLUCOSE INCREASED18
Adverse reaction18
Underdose17
RETCHING17
HYPERPARATHYROIDISM17
COMA17
BLOOD CREATININE INCREASED17
AMNESIA17
VISUAL IMPAIRMENT16
THROAT TIGHTNESS16
SLEEP DISORDER16
RENAL IMPAIRMENT16
NIGHTMARE16
NEPHROLITHIASIS16
LUNG DISORDER16
HYPOGLYCAEMIA16
ERYTHEMA16
DEVICE RELATED INFECTION16
BLOOD ALKALINE PHOSPHATASE INCREASED16
BLISTER16
ARTERIOVENOUS FISTULA SITE COMPLICATION16
SKIN EXFOLIATION15
RECTAL HAEMORRHAGE15
MENTAL DISORDER15
Maternal exposure during pregnancy15
JOINT SWELLING15
DRUG EFFECT DECREASED15
Thyroid operation14
Therapeutic procedure14
PULMONARY EMBOLISM14
PRURITUS GENERALISED14
OROPHARYNGEAL PAIN14
NERVOUSNESS14
MOBILITY DECREASED14
HYPERPHOSPHATAEMIA14
HEART RATE DECREASED14
GASTRIC HAEMORRHAGE14
BLOOD ALBUMIN DECREASED14
ASTHMA14
ARTHRITIS14
UPPER RESPIRATORY TRACT INFECTION13
SWOLLEN TONGUE13
LIMB DISCOMFORT13
LEUKOPENIA13
HYPERPARATHYROIDISM SECONDARY13
GASTRIC ULCER13
Feeding disorder13
DISORIENTATION13
CHRONIC OBSTRUCTIVE PULMONARY DISEASE13
CELLULITIS13
BURNING SENSATION13
ULCER12
THROAT IRRITATION12
RESPIRATORY DISTRESS12
MENTAL STATUS CHANGES12
LIVER DISORDER12
Investigation12
INFLAMMATION12
INCORRECT ROUTE OF DRUG ADMINISTRATION12
HERPES ZOSTER12
HEART RATE IRREGULAR12
GRAND MAL CONVULSION12
GASTROSTOMY TUBE INSERTION12
EPISTAXIS12
BLINDNESS12
BALANCE DISORDER12
Back disorder12
Acute kidney injury12
TETANY11
RENAL HAEMORRHAGE11
PARAESTHESIA ORAL11
OSTEOPOROSIS11
OSTEOMYELITIS11
NEUROPATHY PERIPHERAL11
NECK PAIN11
MIGRAINE11
LIP SWELLING11
Limb operation11
HYPOAESTHESIA ORAL11
HERNIA11
HEPATIC ENZYME INCREASED11
HAEMATOCHEZIA11
HAEMATEMESIS11
GASTROENTERITIS VIRAL11
Fistula11
ENDOTRACHEAL INTUBATION11
DRUG ADMINISTRATION ERROR11
Arthropathy11
VIRAL INFECTION10
UPPER GASTROINTESTINAL HAEMORRHAGE10
Thyroid disorder10
SUICIDAL IDEATION10
SPEECH DISORDER10
SKIN DISCOLOURATION10
Protein total decreased10
POST PROCEDURAL COMPLICATION10
PHARYNGEAL OEDEMA10
NERVOUS SYSTEM DISORDER10
LOCAL SWELLING10
INTESTINAL OBSTRUCTION10
IMPAIRED HEALING10
FEELING HOT10
ERECTILE DYSFUNCTION10
CONTUSION10
CHILLS10
BONE DISORDER10
AGITATION10
Adenoma benign10
UNRESPONSIVE TO STIMULI9
Torticollis9
Staphylococcal infection9
RESTLESS LEGS SYNDROME9
RENAL FAILURE CHRONIC9
Pollakiuria9
PERITONEAL DIALYSIS9
OVERDOSE9
MUSCULOSKELETAL STIFFNESS9
Internal haemorrhage9
HYPOPHOSPHATAEMIA9
HAEMORRHOIDS9
GASTROENTERITIS9
Gallbladder disorder9
Fracture9
ERUCTATION9
EOSINOPHILIA9
Drug ineffective for unapproved indication9
Device issue9
CORONARY ARTERY DISEASE9
CHOLELITHIASIS9
CARDIO-RESPIRATORY ARREST9
BRADYCARDIA9
ANGINA UNSTABLE9
ABORTION SPONTANEOUS9
Vascular graft8
URINE OUTPUT DECREASED8
TOOTH DISORDER8
RESTLESSNESS8
RESPIRATORY DISORDER8
RENAL FAILURE ACUTE8
PRESYNCOPE8
PLATELET COUNT DECREASED8
PERICARDIAL EFFUSION8
OEDEMA8
NEPHROCALCINOSIS8
Medical procedure8
Infarction8
HYPOKALAEMIA8
HEPATIC FAILURE8
GOUT8
Gastrointestinal pain8
GASTRITIS EROSIVE8
FORMICATION8
FOOT AMPUTATION8
Feeding tube user8
Dysphonia8
DYSKINESIA8
DISEASE PROGRESSION8
Cystitis8
Coronary artery bypass8
CONGESTIVE CARDIOMYOPATHY8
Circumstance or information capable of leading to medication error8
Cardiac pacemaker insertion8
Brown tumour8
BREAST CANCER8
Body temperature abnormal8
Blood urine present8
Blood disorder8
WOUND7
VENTRICULAR TACHYCARDIA7
Venous occlusion7
VASCULITIS7
TORSADE DE POINTES7
Thyroidectomy7
ROAD TRAFFIC ACCIDENT7
RESPIRATORY ARREST7
Product monitoring error7
Premature baby7
PARATHYROID GLAND OPERATION7
Parathyroid gland enlargement7
PANCREATITIS ACUTE7
MASS7
Ligament sprain7
Knee operation7
ILEUS7
HYPONATRAEMIA7
HYPERPARATHYROIDISM TERTIARY7
HOT FLUSH7
HIGH TURNOVER OSTEOPATHY7
GANGRENE7
GAMMA-GLUTAMYLTRANSFERASE INCREASED7
Fistula repair7
Femur fracture7
Epigastric discomfort7
End stage renal disease7
DYSURIA7
Dry skin7
DRUG RESISTANCE7
DELIRIUM7
CORONARY ARTERY OCCLUSION7
BLOOD GLUCOSE ABNORMAL7
BACTERIAL INFECTION7
Asphyxia7
ASPARTATE AMINOTRANSFERASE INCREASED7
ALANINE AMINOTRANSFERASE INCREASED7
AGGRESSION7
Ageusia7
VASCULAR ACCESS COMPLICATION6
TRANSPLANT FAILURE6
TRANSIENT ISCHAEMIC ATTACK6
TRANSFUSION6
TINNITUS6
Therapeutic response unexpected6
Skin irritation6
SKIN HAEMORRHAGE6
Skin disorder6
Sinusitis6
SHOCK6
SEPTIC SHOCK6
RHINORRHOEA6
RENAL COLIC6
RASH PAPULAR6
RASH ERYTHEMATOUS6
Product use complaint6
Product dose omission6
Premature delivery6
Post procedural infection6
Poor peripheral circulation6
Oxygen saturation decreased6
OSTEOARTHRITIS6
OESOPHAGEAL CARCINOMA6
Nephrectomy6
NEOPLASM6
Neck surgery6
METABOLIC ACIDOSIS6
MALNUTRITION6
Lung neoplasm malignant6
Lower respiratory tract infection6
LIMB INJURY6
KNEE ARTHROPLASTY6
Irritability6
IMPAIRED GASTRIC EMPTYING6
HYPOXIA6
HYPOMAGNESAEMIA6
HYPERTENSIVE CRISIS6
Hip arthroplasty6
GRAFT COMPLICATION6
Foetal exposure during pregnancy6
FACE OEDEMA6
Exposure during pregnancy6
EPILEPSY6
EJECTION FRACTION DECREASED6
Drug effective for unapproved indication6
DISEASE COMPLICATION6
DEPRESSED LEVEL OF CONSCIOUSNESS6
Deafness6
COLITIS6
CARDIOMEGALY6
Calcinosis6
BLOOD POTASSIUM DECREASED6
BACTERAEMIA6
Atrioventricular block6
ANOREXIA6
ANGIOPATHY6
ABNORMAL BEHAVIOUR6
VOMITING PROJECTILE5
VISUAL ACUITY REDUCED5
VENTRICULAR EXTRASYSTOLES5
VAGINAL HAEMORRHAGE5
Treatment failure5
TRANSAMINASES INCREASED5
Thyroid cancer5
THIRST5
SYSTEMIC LUPUS ERYTHEMATOSUS5
STRESS5
STOMACH DISCOMFORT5
SLUGGISHNESS5
SKIN LESION5
SINUS BRADYCARDIA5
Secretion discharge5
SARCOIDOSIS5
Rib fracture5
RESPIRATORY TRACT INFECTION5
Respiratory tract congestion5
RENAL CYST5
PURPURA5
PROCEDURAL HYPOTENSION5
Pneumothorax5
PNEUMONIA ASPIRATION5
PERIPHERAL VASCULAR DISORDER5
PARATHYROID TUMOUR MALIGNANT5
Parathyroid hyperplasia5
OCULAR HYPERAEMIA5
NIGHT SWEATS5
Musculoskeletal discomfort5
LACRIMATION INCREASED5
Labelled drug-drug interaction medication error5
JOINT INJURY5
Incorrect dosage administered5
HYPOACUSIS5
Hypersomnia5
HEPATITIS5
Heart valve incompetence5
Head injury5
HAEMATOMA5
GENERAL PHYSICAL CONDITION ABNORMAL5
GASTRIC ULCER HAEMORRHAGE5
GASTRIC BYPASS5
Gait inability5
Furuncle5
FREQUENT BOWEL MOVEMENTS5
Foot operation5
FEELING JITTERY5
Facial paralysis5
EYE SWELLING5
Eye operation5
Eye disorder5
ENCEPHALOPATHY5
ELECTROLYTE IMBALANCE5
Dialysis related complication5
CHOLESTASIS5
CARPAL TUNNEL SYNDROME5
CARDIOGENIC SHOCK5
CALCIUM IONISED DECREASED5
BREAST TENDERNESS5
Blood test abnormal5
ATRIOVENTRICULAR BLOCK FIRST DEGREE5
ASCITES5
ANKLE FRACTURE5
ANGER5
ACUTE RESPIRATORY FAILURE5
ACUTE CORONARY SYNDROME5
ACTIVITIES OF DAILY LIVING IMPAIRED5
Acne5
Accidental overdose5
WRONG DRUG ADMINISTERED4
VENTRICULAR FIBRILLATION4
Upper limb fracture4
Therapy change4
Stent placement4
Sinus disorder4
SENSORY DISTURBANCE4
RHABDOMYOLYSIS4
REBOUND EFFECT4
Pulmonary hypertension4
PROTEINURIA4
Protein total increased4
Protein total abnormal4
PROSTATE CANCER4
Productive cough4
PROCEDURAL COMPLICATION4
PIGMENTATION DISORDER4
PHOTOSENSITIVITY REACTION4
PHARYNGITIS4
Pharyngeal disorder4
Peripheral arterial occlusive disease4
Parkinson's disease4
PANCREATIC DISORDER4
OSTEONECROSIS4
ORTHOSTATIC HYPOTENSION4
Oral pain4
Oral disorder4
OESOPHAGITIS4
OBSTRUCTIVE AIRWAYS DISORDER4
NO THERAPEUTIC RESPONSE4
NIPPLE PAIN4
NEURALGIA4
Nerve compression4
MYOCLONUS4
MYOCARDIAL ISCHAEMIA4
MULTIPLE FRACTURES4
MULTI-ORGAN FAILURE4
MOOD SWINGS4
MOOD ALTERED4
Mitral valve incompetence4
Metastases to lung4
METASTASES TO BONE4
METABOLIC DISORDER4
Mental impairment4
MELAENA4
LUNG INFECTION4
LOW TURNOVER OSTEOPATHY4
LIVER FUNCTION TEST ABNORMAL4
LEUKOCYTOCLASTIC VASCULITIS4
KIDNEY TRANSPLANT REJECTION4
Kidney infection4
JEJUNOSTOMY4
JAUNDICE4
INTERNATIONAL NORMALISED RATIO INCREASED4
INTENSIVE CARE4
Injury4
Incorrect route of product administration4
Inappropriate schedule of product administration4
Hypoproteinaemia4
Hyperlipidaemia4
HYPERGLYCAEMIA4
HYPERCALCIURIA4
Hiccups4
Hepatitis C4
Heart rate abnormal4
HAEMOPTYSIS4
HAEMATURIA4
Gastrointestinal tract irritation4
Gastrectomy4
Full blood count decreased4
Foot fracture4
ENDOCARDITIS4
ECZEMA4
Dysstasia4
DUODENITIS4
Diverticulitis4
Disability4
DIPLOPIA4
DERMATITIS ALLERGIC4
Depressed mood4
DENTAL CARIES4
Cyst4
COMPLICATIONS OF TRANSPLANTED KIDNEY4
COLD SWEAT4
Chronic kidney disease4
CEREBRAL HAEMORRHAGE4
CATHETER SITE INFECTION4
CATHETER SITE HAEMORRHAGE4
Cataract4
Cardiac valve disease4
Cardiac murmur4
Cardiac flutter4
BUNDLE BRANCH BLOCK RIGHT4
BRAIN OPERATION4
BONE DENSITY DECREASED4
Blood pressure fluctuation4
Blood count abnormal4
Blindness transient4
BLADDER CANCER4
Bedridden4
ATRIAL FLUTTER4
ASPIRATION4
Arteriovenous fistula thrombosis4
ARTERIOVENOUS FISTULA OCCLUSION4
ARTERIOSCLEROSIS4
ANGIOEDEMA4
ANGINA PECTORIS4
ANAPHYLACTIC REACTION4
Amputation4
Abscess limb4
ABORTION INDUCED4
ABDOMINAL PAIN LOWER4
Wrist fracture3
WOUND INFECTION3
WHITE BLOOD CELL COUNT DECREASED3
VISUAL DISTURBANCE3
VASCULAR CALCIFICATION3
Tricuspid valve incompetence3
TRACHEOSTOMY3
Tooth loss3
Tonsillitis3
Therapeutic product effect incomplete3
Terminal state3
Tendonitis3
SUPRAVENTRICULAR EXTRASYSTOLES3
SUDDEN DEATH3
Stomatitis3
STEVENS-JOHNSON SYNDROME3
STATUS EPILEPTICUS3
Spondylitis3
SPINAL OSTEOARTHRITIS3
Spinal operation3
SPINAL DISORDER3
Sneezing3
SKIN REACTION3
SKIN MASS3
SKIN INFECTION3
SKIN FISSURES3
Skin burning sensation3
SHUNT THROMBOSIS3
Scratch3
SCAB3
Renal transplant failure3
RED BLOOD CELL COUNT DECREASED3
RASH MACULO-PAPULAR3
PULMONARY CONGESTION3
PSYCHOTIC DISORDER3
PSEUDOMONAS INFECTION3
PSEUDOMEMBRANOUS COLITIS3
Product use in unapproved indication3
Product physical consistency issue3
PHARYNGOLARYNGEAL PAIN3
Pelvic fracture3
PARATHYROID TUMOUR3
PARANOIA3
PARALYSIS3
PAPILLOEDEMA3
PANCREATITIS CHRONIC3
Osteopenia3
OSTEITIS DEFORMANS3
OSTEITIS3
OPTIC NEURITIS3
NODULE3
Nasal disorder3
MYOPATHY3
Musculoskeletal chest pain3
MUSCLE TIGHTNESS3
Muscle atrophy3
MITRAL VALVE REPAIR3
MIDDLE INSOMNIA3
MECHANICAL VENTILATION3
Malabsorption3
LYMPHOMA3
Lymphadenopathy3
LEUKOCYTOSIS3
LEFT VENTRICULAR DYSFUNCTION3
Laziness3
LARGE INTESTINE PERFORATION3
Large intestinal haemorrhage3
Joint dislocation3
IRON DEFICIENCY3
Intestinal perforation3
INTESTINAL ISCHAEMIA3
Intervertebral disc protrusion3
Intentional product use issue3
INFECTED SKIN ULCER3
Infected fistula3
Increased appetite3
Implantable defibrillator insertion3
Impaired driving ability3
IMMUNOSUPPRESSANT DRUG LEVEL INCREASED3
ILEOSTOMY3
HYPOTONIA3
Hypokinesia3
Hypochloraemia3
HYPERNATRAEMIA3
Hypermagnesaemia3
Humerus fracture3
Hormone level abnormal3
Hordeolum3
Hip surgery3
HIATUS HERNIA3
Hernia repair3
Hepatocellular injury3
HEPATIC STEATOSIS3
HEPATIC FUNCTION ABNORMAL3
HEPATIC CYST3
HEPATIC CIRRHOSIS3
Hepatic cancer3
Heart valve replacement3
Head discomfort3
HALLUCINATION, AUDITORY3
Hair growth abnormal3
Haemoglobin abnormal3
GYNAECOMASTIA3
Goitre3
GLOSSODYNIA3
Glomerular filtration rate abnormal3
Generalised tonic-clonic seizure3
Gastrointestinal sounds abnormal3
GASTRITIS HAEMORRHAGIC3
Gastric infection3
FUNGAL INFECTION3
FLUSHING3
Fluid intake reduced3
Finger amputation3
Failure to thrive3
EYE PRURITUS3
EXTRADURAL ABSCESS3
Extra dose administered3
EOSINOPHIL COUNT INCREASED3
ELECTROCARDIOGRAM QRS COMPLEX PROLONGED3
Ecchymosis3
EAR INFECTION3
DYSPNOEA EXERTIONAL3
Dysarthria3
DUODENAL ULCER3
DRY THROAT3
Drug prescribing error3
DRUG LEVEL INCREASED3
Diabetic neuropathy3
DERMATITIS3
Delusion3
DEEP VEIN THROMBOSIS3
Decubitus ulcer3
CRYING3
COVID-193
Conjunctivitis3
COLON CANCER3
COAGULOPATHY3
Clostridium difficile infection3
CHOLECYSTITIS3
CHOKING SENSATION3
Choking3
Cervical vertebral fracture3
CEREBRAL ISCHAEMIA3
CEREBRAL INFARCTION3
Catheter placement3
Cataract operation3
CARDIOMYOPATHY3
CACHEXIA3
C-reactive protein increased3
Brain injury3
Blood viscosity decreased3
Blood potassium abnormal3
BLOOD MAGNESIUM DECREASED3
BLOOD LACTATE DEHYDROGENASE INCREASED3
Blood iron decreased3
BLOOD CREATINE PHOSPHOKINASE INCREASED3
BLINDNESS UNILATERAL3
AZOTAEMIA3
Arthritis infective3
Arteriovenous fistula operation3
Arterial occlusive disease3
Aphonia3
APHAGIA3
AORTIC STENOSIS3
Anal incontinence3
Ammonia increased3
AFFECTIVE DISORDER3
ACUTE PULMONARY OEDEMA3
Accident3
Abscess3
ABNORMAL DREAMS3
ABDOMINAL RIGIDITY3
WHITE BLOOD CELL COUNT INCREASED2
Volvulus2
Vitamin D abnormal2
Ventricular hypokinesia2
VENTRICULAR DYSFUNCTION2
VENTRICULAR ARRHYTHMIA2
Venous thrombosis2
Vein disorder2
Vascular graft complication2
Vascular access placement2
Urine calcium increased2
URINARY RETENTION2
Tumour excision2
TROPONIN INCREASED2
Trismus2
TRIGGER FINGER2
TRANSPLANT REJECTION2
Toxicity to various agents2
TOXIC SKIN ERUPTION2
TOOTHACHE2
Tooth extraction2
Tonic convulsion2
TONIC CLONIC MOVEMENTS2
TONGUE OEDEMA2
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED2
Tongue disorder2
Thyroiditis2
Thyroid hormones decreased2
THYROID FUNCTION TEST ABNORMAL2
Thinking abnormal2
Thermal burn2
TENDERNESS2
TACHYPNOEA2
Tachyphylaxis2
SUICIDE ATTEMPT2
SUBDURAL HAEMATOMA2
Staring2
Staphylococcus test positive2
Staphylococcal sepsis2
SPLENOMEGALY2
Splenic rupture2
Spinal fracture2
Spinal cord infection2
SPINAL COLUMN STENOSIS2
SOFT TISSUE INFECTION2
Sleep terror2
Sleep disorder due to general medical condition, insomnia type2
SLEEP APNOEA SYNDROME2
Skin graft2
SHOULDER PAIN2
SENSORY LOSS2
Seasonal allergy2
Sciatica2
Schizophrenia2
SCAR2
Renal pain2
RENAL OSTEODYSTROPHY2
Renal neoplasm2
RENAL MASS2
RENAL HAEMATOMA2
RENAL CELL CARCINOMA2
Renal cancer2
RENAL AND PANCREAS TRANSPLANT2
REFUSAL OF TREATMENT BY PATIENT2
Recurrent cancer2
RASH MACULAR2
Quality of life decreased2
QRS AXIS ABNORMAL2
Pyelonephritis2
Pulmonary thrombosis2
Psychomotor hyperactivity2
Psoriasis2
PROTHROMBIN TIME PROLONGED2
PROSTATECTOMY2
Product prescribing issue2
Product preparation error2
Product availability issue2
PREGNANCY2
PRECOCIOUS PUBERTY2
Pre-eclampsia2
Postoperative wound complication2
PORPHYRIA2
Polyuria2
Polyneuropathy2
Polydipsia2
Poisoning2
Plasma cell myeloma2
Pharyngeal haemorrhage2
PERSONALITY CHANGE2
Peritonitis bacterial2
PERIPHERAL COLDNESS2
Peptic ulcer2
Pathological fracture2
Paronychia2
PARATHYROID HAEMORRHAGE2
PARAPARESIS2
Papule2
Papillary thyroid cancer2
Panic attack2
PANCYTOPENIA2
PANCREATIC CARCINOMA2
PANCREAS TRANSPLANT2
PALLOR2
PAIN IN JAW2
OSTEOSCLEROSIS2
Osteonecrosis of jaw2
Oropharyngeal discomfort2
Oral infection2
Oral discomfort2
OPTIC NEUROPATHY2
OPTIC ISCHAEMIC NEUROPATHY2
OESOPHAGEAL PAIN2
Obstruction gastric2
NON-CARDIAC CHEST PAIN2
NIGHT BLINDNESS2
NEUTROPENIA2
NEUROLOGICAL SYMPTOM2
Nephrogenic anaemia2
NECROTISING FASCIITIS2
Nasal congestion2
NAIL DISORDER2
MYOGLOBIN BLOOD INCREASED2
MYELODYSPLASTIC SYNDROME2
Muscle strain2
MULTIMORBIDITY2
Movement disorder2
Mouth haemorrhage2
Monocytopenia2
Micturition disorder2
METASTASES TO THE MEDIASTINUM2
Metastases to spine2
METABOLIC ENCEPHALOPATHY2
METABOLIC ALKALOSIS2
Medical device complication2
MANIA2
MALIGNANT MELANOMA2
MACULE2
LYMPHOPENIA2
LYMPHOEDEMA2
LUNG INFILTRATION2
LOWER GASTROINTESTINAL HAEMORRHAGE2
LOCALISED OEDEMA2
Localised intraabdominal fluid collection2
Liver injury2
LIPASE INCREASED2
Lip discolouration2
Libido decreased2
Large intestine polyp2
Kidney enlargement2
Ketoacidosis2
JUGULAR VEIN THROMBOSIS2
JOINT STIFFNESS2
Joint range of motion decreased2
Jaw disorder2
JAUNDICE CHOLESTATIC2
ISCHAEMIC STROKE2
Iron overload2
IRON DEFICIENCY ANAEMIA2
Intracranial aneurysm2
Intracardiac thrombus2
Intervertebral disc disorder2
INTERSTITIAL LUNG DISEASE2
Initial insomnia2
Influenza like illness2
Increased viscosity of bronchial secretion2
INCORRECT DRUG DOSAGE FORM ADMINISTERED2
Incoherent2
Hypothyroidism2
Hypoparathyroidism2
Hypoalbuminaemia2
Hyperthyroidism2
HYPERPARATHYROIDISM PRIMARY2
HYPERCHOLESTEROLAEMIA2
Hyperchlorhydria2
HYDRONEPHROSIS2
Hunger2
HEPATOTOXICITY2
HEPATITIS CHOLESTATIC2
HEPATITIS ACUTE2
Hemiparesis2
Heart valve operation2
HAND FRACTURE2
HAEMORRHOIDAL HAEMORRHAGE2
HAEMORRHAGE INTRACRANIAL2
HAEMATOCRIT DECREASED2
Grip strength decreased2
GRAFT THROMBOSIS2
GOUTY ARTHRITIS2
Glomerular filtration rate decreased2
GINGIVAL BLEEDING2
Generalised oedema2
Gastrointestinal infection2
Gastric polyps2
Gallbladder operation2
Fungaemia2
Food allergy2
Fluid imbalance2
FLANK PAIN2
FEMORAL NECK FRACTURE2
FEELING COLD2
Fasciitis2
Faeces hard2
Eye pain2
Eye infection2
Eye haemorrhage2
EXTRAPYRAMIDAL DISORDER2
Escherichia infection2
Erysipelas2
ENTERITIS2
Endocrine disorder2
Electrocardiogram T wave inversion2
ELECTROCARDIOGRAM T WAVE ABNORMAL2
Effusion2
DYSPNOEA PAROXYSMAL NOCTURNAL2
DUODENAL ULCER HAEMORRHAGE2
Drug-induced liver injury2
DRUG TOXICITY2
DRUG EXPOSURE DURING PREGNANCY2
DRUG EFFECT INCREASED2
DIVERTICULUM INTESTINAL2
DIVERTICULUM2
DIFFICULTY IN WALKING2
DIARRHOEA HAEMORRHAGIC2
DIALYSIS DEVICE INSERTION2
Diabetic complication2
Device occlusion2
Device malfunction2
DERMATITIS BULLOUS2
Delayed engraftment2
Defaecation urgency2
DEAFNESS UNILATERAL2
CYANOSIS2
Coronary arterial stent insertion2
Colostomy2
Colonoscopy2
COLITIS ISCHAEMIC2
Colectomy2
Coeliac disease2
CLAVICLE FRACTURE2
CIRCULATORY COLLAPSE2
Chronic gastritis2
Chromaturia2
CHOLECYSTITIS ACUTE2
Chemotherapy2
Cerebrovascular disorder2
CEREBRAL THROMBOSIS2
CATHETERISATION CARDIAC2
Catheter management2
CARPAL TUNNEL DECOMPRESSION2
CARDIOVASCULAR INSUFFICIENCY2
CARDIAC FAILURE CHRONIC2
CALCIUM IONISED INCREASED2
Caesarean section2
Burn oesophageal2
Breast pain2
BREAST MASS2
BRADYARRHYTHMIA2
Bowel movement irregularity2
BONE MARROW FAILURE2
Bone density abnormal2
Body temperature increased2
BLOOD UREA INCREASED2
Blood thyroid stimulating hormone increased2
Blood test2
BLOOD SODIUM DECREASED2
BLOOD GLUCOSE FLUCTUATION2
Blood creatinine abnormal2
BLOOD BILIRUBIN INCREASED2
Blood 25-hydroxycholecalciferol decreased2
Bladder operation2
Bladder disorder2
BILE DUCT CANCER2
BENIGN BONE NEOPLASM2
Basedow's disease2
BASAL CELL CARCINOMA2
Atypical pneumonia2
ARTERIOVENOUS GRAFT THROMBOSIS2
ARTERIOSCLEROSIS OBLITERANS2
APPARENT DEATH2
APHASIA2
AORTIC VALVE REPLACEMENT2
ANGIONEUROTIC OEDEMA2
ALTERED STATE OF CONSCIOUSNESS2
Acute generalised exanthematous pustulosis2
Abscess intestinal2
ABORTION2
ABNORMAL SENSATION IN EYE2
Abnormal faeces2
Abdominal cavity drainage2
XANTHOPSIA1
Wrong product administered1
Wound secretion1
Wound haemorrhage1
WOUND DEHISCENCE1
Wound complication1
Wheezing1
Wheelchair user1
Wernicke's encephalopathy1
Weight abnormal1
Walking aid user1
Vulvovaginal pruritus1
VOMITING IN PREGNANCY1
Vocal cord paralysis1
VITAMIN D DEFICIENCY1
VITAMIN A DEFICIENCY1
VIRAL LOAD INCREASED1
Vestibular neuronitis1
VENTRICULAR HYPERTROPHY1
VENTRICULAR FLUTTER1
Venous thrombosis limb1
VENOUS STENOSIS1
Venous operation1
VENOUS ANEURYSM1
Vena cava thrombosis1
Vein collapse1
VASOSPASM1
Vascular rupture1
Vascular pseudoaneurysm1
Vascular operation1
VASCULAR INSUFFICIENCY1
Vascular encephalopathy1
Vascular dementia1
Vascular access steal syndrome1
Varicocele1
Varices oesophageal1
VARICELLA1
URTICARIA GENERALISED1
UROSEPSIS1
UROGENITAL TRICHOMONIASIS1
Urine odour abnormal1
URINE COLOUR ABNORMAL1
URINE CALCIUM1
Urine abnormality1
Urinary tract disorder1
Urethral obstruction1
Urethral haemorrhage1
Upper-airway cough syndrome1
Underweight1
ULTRAFILTRATION FAILURE1
Ulna fracture1
Ulcer haemorrhage1
Type 1 diabetes mellitus1
Tubulointerstitial nephritis1
Tuberculosis1
Transposition of the great vessels1
TOXIC EPIDERMAL NECROLYSIS1
Tooth infection1
TOOTH FRACTURE1
Tooth discolouration1
TONGUE INJURY1
TONGUE ERUPTION1
Tongue discomfort1
Tongue discolouration1
Tongue blistering1
Toe operation1
Tibia fracture1
Thyroxine free increased1
Thyroid neoplasm1
Thyroid mass1
Thyroid infarction1
Thyroid hormones increased1
Thyroid cyst1
Thrombosis in device1
Thoracotomy1
Thoracic vertebral fracture1
Therapy partial responder1
Therapeutic product ineffective1
Tension1
TENDON RUPTURE1
Temporomandibular joint syndrome1
TEARFULNESS1
TARDIVE DYSKINESIA1
Tachyarrhythmia1
Synovial cyst1
Symptom masked1
Suture insertion1
SUPRAVENTRICULAR TACHYCARDIA1
SUPERIOR VENA CAVAL OCCLUSION1
Sunburn1
SUDDEN HEARING LOSS1
SUDDEN CARDIAC DEATH1
SUBILEUS1
SUBARACHNOID HAEMORRHAGE1
STRESS FRACTURE1
Streptococcus test positive1
STREPTOCOCCAL INFECTION1
Strabismus1
STOMATITIS HAEMORRHAGIC1
Stem cell transplant1
Steal syndrome1
STAPHYLOCOCCAL SKIN INFECTION1
STAPHYLOCOCCAL SCALDED SKIN SYNDROME1
STAPHYLOCOCCAL BACTERAEMIA1
Squamous cell carcinoma of skin1
Squamous cell carcinoma1
Spondylolisthesis1
Spinal pain1
Spinal cord injury1
SPINAL CORD COMPRESSION1
Speech rehabilitation1
SOFT TISSUE NECROSIS1
SOFT TISSUE DISORDER1
Small intestine carcinoma1
Small intestinal ulcer perforation1
Small intestinal perforation1
Small intestinal obstruction1
Small intestinal haemorrhage1
Sleep disorder due to a general medical condition1
SKULL FRACTURED BASE1
Skull fracture1
SKIN ULCER HAEMORRHAGE1
Skin papilloma1
Skin oedema1
Skin odour abnormal1
SKIN NECROSIS1
Skin cancer1
Skin bacterial infection1
Skin abrasion1
Sjogren's syndrome1
SINUS TACHYCARDIA1
Sinus congestion1
Sinobronchitis1
Sickle cell anaemia1
SICK SINUS SYNDROME1
Shunt occlusion1
Shunt infection1
SERUM FERRITIN INCREASED1
SEROMA1
Septic arthritis staphylococcal1
SENSITIVITY OF TEETH1
Sensation of foreign body1
Self-injurious ideation1
Seizure like phenomena1
Scrotal disorder1
SCREAMING1
SCLERAL DISCOLOURATION1
SCAPULA FRACTURE1
Salivary hypersecretion1
Saliva altered1
Right atrial enlargement1
Rhinovirus infection1
Rheumatoid arthritis1
REVERSIBLE AIRWAYS OBSTRUCTION1
RETROPERITONEAL HAEMORRHAGE1
RETINAL HAEMORRHAGE1
RETINAL DETACHMENT1
Retinal degeneration1
Respiratory tract oedema1
RESPIRATORY ALKALOSIS1
Replacement of ambulatory peritoneal catheter1
Renal tubular atrophy1
Renal surgery1
RENAL EMBOLISM1
Renal atrophy1
Renal artery stenosis1
Renal adenoma1
Regurgitation1
Refractory cytopenia with unilineage dysplasia1
REFRACTORY ANAEMIA1
REFLUX OESOPHAGITIS1
Rectal ulcer haemorrhage1
Reaction to food colouring1
Raynaud's phenomenon1
RASH VESICULAR1
Rash pustular1
RASH MORBILLIFORM1
Radius fracture1
QUADRIPARESIS1
Pyuria1
Pupillary reflex impaired1
Puncture site infection1
Pulse absent1
Pulmonary mass1
PULMONARY HAEMORRHAGE1
PULMONARY FUNCTION TEST DECREASED1
Pulmonary calcification1
Psychotic symptom1
Psychotic behaviour1
PSYCHIATRIC DECOMPENSATION1
Pseudofracture1
Protein urine present1
Prostatomegaly1
Prostatitis1
Prostatic disorder1
Product storage error1
Product solubility abnormal1
Product size issue1
Product quality issue1
Product packaging quantity issue1
Product label issue1
Product label confusion1
Product dose omission issue1
Product dispensing issue1
Product dispensing error1
Product difficult to swallow1
Product communication issue1
Product colour issue1
Procedural pain1
Procedural nausea1
Procedural hypertension1
Premature rupture of membranes1
PREGNANCY TEST FALSE POSITIVE1
Potentiating drug interaction1
POSTOPERATIVE INFECTION1
POSTICTAL STATE1
Posterior reversible encephalopathy syndrome1
Post-tussive vomiting1
Post procedural swelling1
Post procedural haemorrhage1
Poor quality sleep1
Poor quality drug administered1
Polyomavirus-associated nephropathy1
Polymyalgia rheumatica1
POLYMEDICATION1
Polyhydramnios1
POLYCYTHAEMIA1
Polycystic ovaries1
Polycystic liver disease1
Pneumoperitoneum1
PLEURITIC PAIN1
PLEURAL DISORDER1
Placenta praevia haemorrhage1
Placenta praevia1
PITYRIASIS ROSEA1
Pituitary apoplexy1
PHOTOPHOBIA1
Phosphaturic mesenchymal tumour1
Phlebitis1
Pharyngeal operation1
Pharyngeal mass1
PETECHIAE1
PERSONALITY CHANGE DUE TO A GENERAL MEDICAL CONDITION1
PERITONEAL DISORDER1
Peripheral venous disease1
Peripheral sensory neuropathy1
Peripheral ischaemia1
Peripheral embolism1
PERIORBITAL HAEMATOMA1
PERICARDITIS URAEMIC1
PERICARDITIS1
PERICARDIAL HAEMORRHAGE1
Pericardial disease1
PENILE DISCHARGE1
Pemphigoid1
Pelvic deformity1
Patella fracture1
PARTIAL SEIZURES1
PAROXYSMAL CHOREOATHETOSIS1
PARATHYROID SCAN ABNORMAL1
PARATHYROID HORMONE-RELATED PROTEIN ABNORMAL1
Parathyroid cyst1
Paranasal sinus hypersecretion1
Paradoxical drug reaction1
PANCREATIC PSEUDOCYST1
PANCREATIC ENZYMES INCREASED1
Pancreatic cyst1
Pancreas infection1
Palliative care1
Oxygen therapy1
Overweight1
Ovarian cancer1
Otitis media1
Otitis externa1
OSTEOTOMY1
OSTEOMALACIA1
Osteoma1
Osteolysis1
Osteodystrophy1
ORTHOPNOEA1
Organising pneumonia1
Organ transplant1
Organ failure1
Oral neoplasm1
Oral mucosal exfoliation1
Oral mucosal eruption1
Oral mucosal discolouration1
Oral mucosal blistering1
Oral administration complication1
OPHTHALMOPLEGIA1
OPEN WOUND1
Onychoclasis1
Oncocytoma1
Oliguria1
OESOPHAGITIS ULCERATIVE1
Oesophageal spasm1
Oesophageal irritation1
Oesophageal hypomotility1
OEDEMATOUS PANCREATITIS1
OCCULT BLOOD POSITIVE1
Obstructive nephropathy1
Obstruction1
Obesity1
Nosocomial infection1
Normochromic normocytic anaemia1
NONSPECIFIC REACTION1
NON-CARDIOGENIC PULMONARY OEDEMA1
Nocturnal dyspnoea1
Nipple swelling1
Neutrophil count increased1
NEUTROPHIL COUNT DECREASED1
NEURODERMATITIS1
Nerve injury1
NEPHROTIC SYNDROME1
NEPHROPATHY TOXIC1
Nephropathy1
NEPHROGENIC SYSTEMIC FIBROSIS1
Nephrogenic diabetes insipidus1
Neoplasm recurrence1
NEOPLASM GROWTH ACCELERATED1
Negative thoughts1
Necrosis1
NECK MASS1
Neck exploration1
Nasal operation1
Nasal obstruction1
Nasal dryness1
N-telopeptide urine increased1
Myocardial oedema1
Myelopathy1
Myelofibrosis1
Mydriasis1
Myasthenia gravis1
Musculoskeletal injury1
MUSCLE SWELLING1
MUSCLE CONTRACTIONS INVOLUNTARY1
Multiple organ dysfunction syndrome1
MULTIPLE MYELOMA1
Multiple endocrine neoplasia Type 11
Multiple allergies1
MUCOSAL INFLAMMATION1
MUCOSAL DISCOLOURATION1
Mouth ulceration1
Mixed liver injury1
Mitral valve stenosis1
Mitral valve replacement1
Mitral valve disease1
MINERAL METABOLISM DISORDER1
Micturition urgency1
MICROCYTIC ANAEMIA1
Metastatic malignant melanoma1
Metastasis1
Metastases to liver1
Metastases to gastrointestinal tract1
Metastases to diaphragm1
Metabolic surgery1
Mental retardation1
MENISCUS LESION1
MENINGITIS LISTERIA1
Meningitis1
Medication residue present1
MEDICAL OBSERVATION1
Medical device site infection1
Medical device change1
MATERNAL DRUGS AFFECTING FOETUS1
Mass excision1
MALLORY-WEISS SYNDROME1
MALIGNANT NEOPLASM PROGRESSION1
MALIGNANT HYPERTENSION1
MAJOR DEPRESSION1
MACULAR DEGENERATION1
MACROGLOSSIA1
Lymphocele1
LYMPHANGITIS1
Lymphadenectomy1
LUNG TRANSPLANT1
Lung operation1
LUNG NEOPLASM1
Lumbar spinal stenosis1
Lower respiratory tract congestion1
Lower extremity mass1
Low birth weight baby1
Loss of personal independence in daily activities1
LOSS OF LIBIDO1
LOGORRHOEA1
LOBAR PNEUMONIA1
LISTERIOSIS1
LIPASE ABNORMAL1
LIP OEDEMA1
LIP DISORDER1
LIGAMENT INJURY1
Lichenoid keratosis1
LEUKOENCEPHALOPATHY1
Leukaemia1
LEFT VENTRICULAR FAILURE1
Left atrial enlargement1
LATEX ALLERGY1
Laryngitis1
LARYNGEAL OEDEMA1
Laryngeal injury1
Lacunar infarction1
Laceration1
Laboratory test normal1
LABORATORY TEST INTERFERENCE1
Labile hypertension1
KYPHOSIS1
KLEBSIELLA SEPSIS1
Kidney fibrosis1
Jugular vein occlusion1
Joint warmth1
Joint instability1
Jaw operation1
Ischaemia1
Irritable bowel syndrome1
Investigation abnormal1
INTRAVASCULAR HAEMOLYSIS1
Intraocular pressure increased1
INTRACRANIAL PRESSURE INCREASED1
Intestinal resection1
INTESTINAL INFARCTION1
Intestinal gangrene1
Intervertebral discitis1
Intervertebral disc space narrowing1
Intervertebral disc operation1
Intervertebral disc displacement1
International normalised ratio abnormal1
INTENTIONAL MISUSE1
Inner ear disorder1
Injection site pain1
INHIBITORY DRUG INTERACTION1
Inguinal hernia1
Infusion site pain1
Infusion site extravasation1
Inflammatory bowel disease1
INFECTIOUS PERITONITIS1
Infectious colitis1
Infected bite1
INCREASED UPPER AIRWAY SECRETION1
INCREASED TENDENCY TO BRUISE1
Increased bronchial secretion1
Incorrect product storage1
Incorrect drug administration duration1
Incontinence1
Incision site pain1
Incarcerated hernia1
INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION1
Inadequate haemodialysis1
IMPULSE-CONTROL DISORDER1
Impaired work ability1
Impaired self-care1
Impaired quality of life1
Immunosuppression1
IMMUNE SYSTEM DISORDER1
Illness1
Ileus paralytic1
Ileectomy1
IgA nephropathy1
HYPOVOLAEMIA1
HYPOTHERMIA1
HYPOGLYCAEMIC COMA1
HYPOGEUSIA1
HYPOCHROMIC ANAEMIA1
HYPOCALCIURIA1
HYPOAESTHESIA FACIAL1
HYPERVISCOSITY SYNDROME1
Hypervigilance1
HYPERTONIA1
HYPERTHERMIA1
Hyperpyrexia1
Hyperplasia1
Hyperphosphaturia1
Hyperkeratosis1
Hyperinsulinaemic hypoglycaemia1
HYPERCAPNIA1
Hyperchloraemia1
HYPERCALCAEMIC NEPHROPATHY1
Hyperbilirubinaemia1
Hydrothorax1
HIV infection1
Hidradenitis1
HERPES SIMPLEX1
Hernia pain1
Hepatomegaly1
Hepatitis fulminant1
Hepatic pain1
HEPATIC NEOPLASM1
HEPATIC NECROSIS1
HEPATIC MASS1
Hepatic infection1
Hepatic haemorrhage1
Hepatic encephalopathy1
Heart valve stenosis1
HEART RATE1
Heart disease congenital1
Head titubation1
HEAD AND NECK CANCER1
Hallucinations, mixed1
HALLUCINATION, VISUAL1
Hair follicle tumour benign1
HAEMORRHAGIC DIATHESIS1
HAEMOLYTIC ANAEMIA1
Haemoglobinaemia1
Haemoglobin increased1
Haemodynamic instability1
HAEMATOTOXICITY1
HAEMARTHROSIS1
Haemangioma of skin1
Grief reaction1
GRAFT DYSFUNCTION1
GLYCOSYLATED HAEMOGLOBIN INCREASED1
Glomerulonephritis1
Glaucoma1
Gestational hypertension1
Genital tract inflammation1
Genital lesion1
Gastrooesophageal sphincter insufficiency1
GASTROINTESTINAL VIRAL INFECTION1
Gastrointestinal ulcer haemorrhage1
Gastrointestinal toxicity1
Gastrointestinal stoma complication1
GASTROINTESTINAL OBSTRUCTION1
Gastrointestinal motility disorder1
Gastrointestinal malformation1
GASTROINTESTINAL HYPOMOTILITY1
GASTROINTESTINAL CANDIDIASIS1
Gastrointestinal angiectasia1
GASTROENTERITIS SALMONELLA1
GASTRODUODENITIS1
Gastritis bacterial1
Gastric operation1
Gastric neoplasm1
GASTRIC CANCER1
Gastric antral vascular ectasia1
GAMMOPATHY1
GAMMA-GLUTAMYLTRANSFERASE ABNORMAL1
Gallbladder polyp1
Fungal oesophagitis1
Frustration tolerance decreased1
Fractured coccyx1
FRACTURE NONUNION1
Foreign body1
Food refusal1
Food poisoning1
Food intolerance1
Foetal growth restriction1
Fibromyalgia1
Fibroblast growth factor 23 increased1
Feeling of despair1
Feeling drunk1
Feeding tube complication1
Feeding intolerance1
Fear of death1
Faeces soft1
Eyelid boil1
Eye movement disorder1
Eye luxation1
Eye irritation1
Eye contusion1
Expired product administered1
Expired drug administered1
EXOSTOSIS1
Exophthalmos1
EXFOLIATIVE RASH1
ERYTHEMA NODOSUM1
ERYTHEMA MULTIFORME1
EPIGLOTTIC OEDEMA1
Enzyme level increased1
Enzyme inhibition1
ENTEROBACTER SEPSIS1
Enteritis infectious1
Endometrial cancer1
Endocarditis staphylococcal1
ENCEPHALOMALACIA1
Emotional distress1
Embolism arterial1
Embolism1
ELECTROMECHANICAL DISSOCIATION1
ELECTROENCEPHALOGRAM ABNORMAL1
ELECTROCARDIOGRAM ST-T SEGMENT ABNORMAL1
ELECTROCARDIOGRAM ST SEGMENT DEPRESSION1
Electrocardiogram RR interval prolonged1
Electrocardiogram QT shortened1
ELECTROCARDIOGRAM CHANGE1
ELECTROCARDIOGRAM ABNORMAL1
Elective procedure1
ECHOCARDIOGRAM ABNORMAL1
Ear discomfort1
Dystrophic calcification1
Dysphemia1
Dysmenorrhoea1
Dysentery1
Dyschezia1
Duodenal perforation1
Duodenal operation1
DRY GANGRENE1
Dry eye1
Drug withdrawal syndrome1
Drug tolerance decreased1
Drug titration error1
Drug effect less than expected1
Drug effect faster than expected1
DRUG DISPENSING ERROR1
Drug dependence1
DRUG DELIVERY SYSTEM MALFUNCTION1
Diverticulitis intestinal haemorrhagic1
Disturbance in attention1
Disorganised speech1
Disease recurrence1
Diplegia1
DILATATION ATRIAL1
DIEULAFOY'S VASCULAR MALFORMATION1
Diet noncompliance1
DIASTOLIC DYSFUNCTION1
DIALYSIS DEVICE COMPLICATION1
DIABETIC RETINOPATHY1
DIABETIC MICROANGIOPATHY1
Diabetic foot infection1
Diabetic coma1
Diabetes insipidus1
DEVICE RELATED SEPSIS1
DEVICE FAILURE1
Device dislocation1
Developmental delay1
DERMATITIS EXFOLIATIVE1
Dermatitis contact1
DERMAL CYST1
DEPENDENCE ON ENABLING MACHINE OR DEVICE1
Dental plaque1
Delayed graft function1
Decreased immune responsiveness1
DECREASED ACTIVITY1
Deafness bilateral1
Daydreaming1
Dandruff1
Cytomegalovirus test positive1
CYTOLYTIC HEPATITIS1
Cyst removal1
CUSHINGOID1
Crystalluria1
Crystal deposit intestine1
Cryptorchism1
Cryoglobulinaemia1
Crohn's disease1
Craniotomy1
Craniocerebral injury1
Costochondritis1
Coronary artery thrombosis1
CORONARY ARTERY STENOSIS1
COORDINATION ABNORMAL1
CONVERSION DISORDER1
Continuous positive airway pressure1
Congenital central nervous system anomaly1
CONCUSSION1
CONCOMITANT DISEASE PROGRESSION1
Computerised tomogram1
Compression fracture1
Complication of device removal1
Complication associated with device1
COMPLEX PARTIAL SEIZURES1
COMA URAEMIC1
Colposcopy1
Colorectal cancer1
Colorectal adenoma1
Colonic abscess1
Colon operation1
Colon dysplasia1
COGWHEEL RIGIDITY1
Cognitive disorder1
Coccidioidomycosis1
Coagulation time prolonged1
CLOSTRIDIUM TEST POSITIVE1
Clostridium difficile colitis1
CLOSTRIDIUM COLITIS1
Chronic kidney disease-mineral and bone disorder1
CHOREA1
Chondrocalcinosis pyrophosphate1
CHONDROCALCINOSIS1
Cholelithotomy1
Cholecystitis infective1
Cholecystectomy1
CHOLANGITIS1
CHOLANGIOLITIS1
Chest wall abscess1
CHEST TUBE INSERTION1
Cervix carcinoma1
CERVICAL CORD COMPRESSION1
Cerumen impaction1
CEREBRAL ATROPHY1
CEREBELLAR SYNDROME1
CEREBELLAR ISCHAEMIA1
Central venous catheterisation1
CENTRAL NERVOUS SYSTEM LESION1
Central nervous system infection1
Catheter site pain1
Cast application1
Carotid bruit1
Carotid artery stenosis1
CAROTID ARTERY ATHEROMA1
Carditis1
Cardioversion1
CARDIAC VENTRICULAR DISORDER1
CARDIAC TAMPONADE1
Cardiac infection1
Cardiac fibrillation1
Cardiac failure acute1
Cardiac discomfort1
Cardiac death1
Cardiac aneurysm1
Carbon dioxide decreased1
Carbohydrate antigen 125 increased1
Cancer surgery1
Calculus urinary1
Calculus bladder1
CALCIUM PHOSPHATE PRODUCT INCREASED1
CALCIUM METABOLISM DISORDER1
Calcium ionised abnormal1
C-telopeptide decreased1
Burnout syndrome1
BUNDLE BRANCH BLOCK LEFT1
BRONCHITIS ACUTE1
Bronchial obstruction1
Breast swelling1
Breast enlargement1
BREAST DISCHARGE1
Breast cancer recurrent1
Breast cancer metastatic1
Breast cancer male1
BRAIN STEM INFARCTION1
Brain hypoxia1
Boredom1
Bone scan abnormal1
Bone operation1
Bone neoplasm1
Bone metabolism disorder1
BONE GIANT CELL TUMOUR1
BONE FORMATION TEST ABNORMAL1
BONE FISSURE1
Bone density increased1
Bone cyst1
Body height decreased1
Blood urea decreased1
Blood urea abnormal1
Blood thyroid stimulating hormone abnormal1
BLOOD TESTOSTERONE DECREASED1
Blood pressure systolic decreased1
Blood pressure measurement1
Blood pH decreased1
Blood pH abnormal1
Blood parathyroid hormone1
Blood osmolarity increased1
Blood magnesium increased1
Blood magnesium abnormal1
Blood lactic acid increased1
Blood iron increased1
Blood immunoglobulin E increased1
Blood gastrin increased1
BLOOD CREATINE PHOSPHOKINASE MB INCREASED1
BLOOD CREATINE INCREASED1
Blood cholesterol increased1
Blood cholesterol decreased1
BLOOD CHLORIDE DECREASED1
Blood chloride abnormal1
Blood bilirubin abnormal1
BLOOD AMYLASE INCREASED1
Blood alkaline phosphatase decreased1
Blepharospasm1
BLEEDING TIME PROLONGED1
Bladder pain1
Bladder discomfort1
BK virus infection1
Bipolar disorder1
Biopsy lung1
Biopsy bone marrow1
Bile duct obstruction1
BIFASCICULAR BLOCK1
Benign pancreatic neoplasm1
BARRETT'S OESOPHAGUS1
Bacterial toxaemia1
Back injury1
AUTONOMIC NEUROPATHY1
Autoimmune haemolytic anaemia1
ATRIOVENTRICULAR BLOCK SECOND DEGREE1
ATRIOVENTRICULAR BLOCK COMPLETE1
Atrial thrombosis1
ATELECTASIS1
Aspiration bronchial1
ASPARTATE AMINOTRANSFERASE ABNORMAL1
Arteriovenous fistula site haemorrhage1
Arteriovenous fistula maturation failure1
Arteriovenous fistula aneurysm1
ARTERIOSCLEROTIC GANGRENE1
Arteriosclerosis coronary artery1
Arterial thrombosis1
Arterial therapeutic procedure1
Arterial stenosis1
ARTERIAL SPASM1
Arterial rupture1
Arterial disorder1
APNOEA1
Apathy1
Apallic syndrome1
AORTIC VALVE SCLEROSIS1
Aortic valve repair1
Aortic valve incompetence1
Aortic rupture1
Aortic dissection1
Aortic arteriosclerosis1
Aortic aneurysm rupture1
Anxiety disorder1
ANURIA1
ANTIPSYCHOTIC DRUG LEVEL BELOW THERAPEUTIC1
Antiphospholipid syndrome1
ANTICONVULSANT DRUG LEVEL BELOW THERAPEUTIC1
ANTICOAGULATION DRUG LEVEL ABOVE THERAPEUTIC1
ANTIBIOTIC RESISTANT STAPHYLOCOCCUS TEST POSITIVE1
ANORGASMIA1
Anorectal infection1
Anorectal disorder1
Anion gap1
ANGIOSCLEROSIS1
Angioplasty1
Angiogram1
ANGIODYSPLASIA1
Aneurysm ruptured1
ANEURYSM ARTERIOVENOUS1
ANASTOMOTIC ULCER HAEMORRHAGE1
Anastomotic stenosis1
Anaphylactic shock1
AMYLOIDOSIS1
Amputee1
Alpha haemolytic streptococcal infection1
ALCOHOL POISONING1
Alcohol intolerance1
ALBINISM1
ALANINE AMINOTRANSFERASE ABNORMAL1
AFFECT LABILITY1
ADRENAL CARCINOMA1
ADRENAL ADENOMA1
Acute respiratory distress syndrome1
ACUTE PSYCHOSIS1
Acute phase reaction1
Acute abdomen1
Acquired hypocalciuric hypercalcaemia1
Acquired cystic kidney disease1
Acidosis1
Accidental exposure to product by child1
Accessory spleen1
ABSCESS NECK1
ABDOMINAL STRANGULATED HERNIA1
Abdominal mass1
Abdominal infection1
Abdominal hernia repair1
ABDOMINAL HERNIA1
ABDOMINAL ABSCESS1





Filtered ChEMBL targets:

Target UniProtKB ID Activity in nm Target Name Target gene
P10635 50 Cytochrome P450 2D6 CP2D6_HUMAN
P23415 320 Glycine receptor subunit alpha-1 GLRA1_HUMAN
P41180 80 Extracellular calcium-sensing receptor CASR_HUMAN



Toxicity information:

Toxicity class: 3
Toxicity type: N/A
LD50: 300 mg/kg



External links:

ChEBML: CHEMBL1201284
DrugBank: DB01012