telithromycin


EMA42



General information:


Withdrawn ID: EMA42
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es): J01FA15
Molecular Formula: C43H65N5O10
Molweight: 812.018



Withdrawal information:


Withdrawn due to drug safety reasons:No



Side-effects:

Total reported cases (submitted by medical professionals) with telithromycin as primary suspect: 1237


Reported final outcomes:
Hospitalization (initial or prolonged): 417
Death: 83
Life-Threatening condition: 80
Disability: 47
Intervention required to prevent permanent impairment/damage: 18
Congenital anomaly: 1


Reported side-effects:

Side-effect Case number
NAUSEA177
ASPARTATE AMINOTRANSFERASE INCREASED154
ALANINE AMINOTRANSFERASE INCREASED151
VISION BLURRED145
PYREXIA123
FATIGUE122
VOMITING114
HEPATITIS107
DYSPNOEA100
JAUNDICE90
ASTHENIA89
DIZZINESS84
HEPATIC ENZYME INCREASED80
BLOOD ALKALINE PHOSPHATASE INCREASED77
BLOOD BILIRUBIN INCREASED76
DIARRHOEA72
ABDOMINAL PAIN71
LIVER FUNCTION TEST ABNORMAL68
MALAISE63
LOSS OF CONSCIOUSNESS63
ABDOMINAL PAIN UPPER59
DIPLOPIA53
CHROMATURIA51
VISUAL DISTURBANCE47
HEPATIC FAILURE47
PRURITUS45
RASH40
INTERNATIONAL NORMALISED RATIO INCREASED39
CHEST PAIN39
HYPERHIDROSIS38
HEADACHE38
PAIN34
CHILLS34
TACHYCARDIA33
HYPOTENSION32
BLOOD CREATININE INCREASED32
OEDEMA PERIPHERAL31
HYPERSENSITIVITY31
DRUG INTERACTION31
RENAL FAILURE29
PALPITATIONS29
MYALGIA29
DRUG INEFFECTIVE28
ARTHRALGIA28
WEIGHT DECREASED27
FEELING ABNORMAL27
ANOREXIA27
ABDOMINAL DISTENSION27
THROMBOCYTOPENIA25
RESPIRATORY FAILURE25
LIVER DISORDER25
COUGH25
WHITE BLOOD CELL COUNT INCREASED24
HEPATIC STEATOSIS24
GAMMA-GLUTAMYLTRANSFERASE INCREASED24
FALL24
CONFUSIONAL STATE24
ASCITES24
PLEURAL EFFUSION23
DEHYDRATION23
TREMOR22
RENAL FAILURE ACUTE22
URTICARIA21
TRANSAMINASES INCREASED21
DECREASED APPETITE21
COAGULOPATHY21
HEPATOTOXICITY20
CONVULSION20
BLOOD PRESSURE INCREASED20
ANAEMIA20
SYNCOPE19
DEPRESSED LEVEL OF CONSCIOUSNESS19
ARRHYTHMIA19
SWELLING FACE18
PROTHROMBIN TIME PROLONGED18
LETHARGY18
HYPOAESTHESIA18
HEPATOMEGALY18
HEART RATE INCREASED18
BILIRUBIN CONJUGATED INCREASED18
PNEUMONIA17
MUSCULAR WEAKNESS17
DYSGEUSIA17
BLOOD LACTATE DEHYDROGENASE INCREASED17
ABDOMINAL DISCOMFORT17
VISUAL ACUITY REDUCED16
SPLENOMEGALY16
RHABDOMYOLYSIS16
BLOOD CREATINE PHOSPHOKINASE INCREASED16
VERTIGO15
PARAESTHESIA15
MYASTHENIA GRAVIS15
HEPATOCELLULAR DAMAGE15
HEPATITIS ACUTE15
HEPATIC FUNCTION ABNORMAL15
BLOOD GLUCOSE INCREASED15
BACK PAIN15
OCULAR ICTERUS14
BLOOD UREA INCREASED14
SOMNOLENCE13
SINUSITIS13
RED BLOOD CELL SEDIMENTATION RATE INCREASED13
MULTI-ORGAN FAILURE13
INJURY13
HYPERTENSION13
HEPATIC CIRRHOSIS13
HAEMOGLOBIN DECREASED13
CONDITION AGGRAVATED13
CARDIAC ARREST13
ATRIAL FIBRILLATION13
ACCOMMODATION DISORDER13
URINARY TRACT INFECTION12
STEVENS-JOHNSON SYNDROME12
RESPIRATORY DISTRESS12
EOSINOPHILIA12
EOSINOPHIL COUNT INCREASED12
DEATH12
BLOOD SODIUM DECREASED12
BLOOD ALBUMIN DECREASED12
ANXIETY12
SWELLING11
SHOCK11
SEPSIS11
PAIN IN EXTREMITY11
LYMPHADENOPATHY11
INSOMNIA11
HYPOKALAEMIA11
HALLUCINATION11
DYSPHAGIA11
SWOLLEN TONGUE10
SEPTIC SHOCK10
RENAL IMPAIRMENT10
MENTAL STATUS CHANGES10
MEDICATION ERROR10
LEUKOPENIA10
HYPOGLYCAEMIA10
HEPATITIS TOXIC10
HEPATIC NECROSIS10
GENERAL PHYSICAL HEALTH DETERIORATION10
FAECES PALE10
CIRCULATORY COLLAPSE10
VENTRICULAR EXTRASYSTOLES9
RESPIRATORY ARREST9
RED BLOOD CELL COUNT DECREASED9
PULMONARY OEDEMA9
NEUTROPENIA9
NEPHRITIS INTERSTITIAL9
MYDRIASIS9
HYPONATRAEMIA9
GENERALISED OEDEMA9
GAIT DISTURBANCE9
ERYTHEMA9
DRUG ERUPTION9
CYTOLYTIC HEPATITIS9
CONSTIPATION9
CHOLELITHIASIS9
CARDIAC FAILURE CONGESTIVE9
BRADYCARDIA9
BLOOD PRESSURE DECREASED9
BLOOD CHLORIDE DECREASED9
BLINDNESS TRANSIENT9
APHASIA9
VISUAL BRIGHTNESS8
VIRAL INFECTION8
RESPIRATORY DISORDER8
PLATELET COUNT DECREASED8
PANCREATITIS8
OEDEMA8
LIPASE INCREASED8
INFLUENZA LIKE ILLNESS8
IMPAIRED WORK ABILITY8
HAEMATOCRIT DECREASED8
GALLBLADDER DISORDER8
EYE PAIN8
EJECTION FRACTION DECREASED8
DISORIENTATION8
BLINDNESS8
AUTOIMMUNE HEPATITIS8
ANTINUCLEAR ANTIBODY POSITIVE8
ANOSMIA8
ANAPHYLACTIC SHOCK8
ACUTE RESPIRATORY DISTRESS SYNDROME8
ABDOMINAL TENDERNESS8
STOMATITIS7
RASH ERYTHEMATOUS7
PHOTOPSIA7
NERVOUS SYSTEM DISORDER7
MYOCARDIAL INFARCTION7
MUSCLE SPASMS7
JOINT SWELLING7
HAEMATURIA7
FAECES DISCOLOURED7
EPISTAXIS7
CONTUSION7
CHOLECYSTITIS7
BODY TEMPERATURE INCREASED7
BALANCE DISORDER7
AGEUSIA7
ACUTE HEPATIC FAILURE7
ABASIA7
WHITE BLOOD CELL COUNT DECREASED6
WHEEZING6
VENTRICULAR FIBRILLATION6
UNEVALUABLE EVENT6
THROAT TIGHTNESS6
SYNCOPE VASOVAGAL6
SUPRAVENTRICULAR EXTRASYSTOLES6
SPEECH DISORDER6
ROAD TRAFFIC ACCIDENT6
PROTEINURIA6
POLLAKIURIA6
PHARYNGOLARYNGEAL PAIN6
PANCYTOPENIA6
MYOPATHY6
METABOLIC ACIDOSIS6
LEUKOCYTOSIS6
INTERNATIONAL NORMALISED RATIO DECREASED6
INFLAMMATION6
HYPERGLYCAEMIA6
HEPATITIS FULMINANT6
HEPATIC TRAUMA6
HEPATIC ENCEPHALOPATHY6
HEART RATE IRREGULAR6
HAEMORRHAGE6
HAEMATEMESIS6
FACE OEDEMA6
DYSURIA6
DRUG EXPOSURE DURING PREGNANCY6
COMA6
CHOLESTASIS6
CHEST DISCOMFORT6
CARDIO-RESPIRATORY ARREST6
CARDIAC FAILURE6
BRONCHITIS6
BLOOD AMYLASE INCREASED6
ANGIONEUROTIC OEDEMA6
AMMONIA INCREASED6
ACTIVITIES OF DAILY LIVING IMPAIRED6
ACIDOSIS6
WEIGHT INCREASED5
VISUAL IMPAIRMENT5
VENTRICULAR TACHYCARDIA5
URTICARIA GENERALISED5
TROPONIN INCREASED5
TREATMENT NONCOMPLIANCE5
THINKING ABNORMAL5
THERAPY NON-RESPONDER5
SINUS TACHYCARDIA5
SERUM SICKNESS5
SERUM FERRITIN INCREASED5
RETCHING5
RESPIRATORY RATE INCREASED5
RENAL FAILURE CHRONIC5
RASH GENERALISED5
PHOTOPHOBIA5
PERICARDIAL EFFUSION5
PARALYSIS5
ORAL CANDIDIASIS5
NERVOUSNESS5
MYOCARDIAL ISCHAEMIA5
MITRAL VALVE INCOMPETENCE5
MENTAL DISORDER5
ISCHAEMIC HEPATITIS5
INTERSTITIAL LUNG DISEASE5
IMPAIRED DRIVING ABILITY5
HAEMATOCHEZIA5
GLOSSODYNIA5
GASTROINTESTINAL DISORDER5
FLUSHING5
FEELING HOT5
EPSTEIN-BARR VIRUS INFECTION5
DRUG TOXICITY5
DISTURBANCE IN ATTENTION5
DISSEMINATED INTRAVASCULAR COAGULATION5
DIALYSIS5
COLOUR BLINDNESS5
COLD SWEAT5
CEREBRAL INFARCTION5
CARDIAC DISORDER5
C-REACTIVE PROTEIN INCREASED5
BRAIN OEDEMA5
BLOOD POTASSIUM DECREASED5
BLOOD IMMUNOGLOBULIN G INCREASED5
BLOOD CHOLESTEROL INCREASED5
ATELECTASIS5
ANGIOEDEMA5
ANAPHYLACTIC REACTION5
AMNESIA5
ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED5
ABDOMINAL PAIN LOWER5
YELLOW SKIN4
VARICES OESOPHAGEAL4
URINE OUTPUT DECREASED4
URINARY RETENTION4
UPPER RESPIRATORY TRACT INFECTION4
TRICUSPID VALVE INCOMPETENCE4
TOXIC EPIDERMAL NECROLYSIS4
THIRST4
TACHYPNOEA4
SUPRAVENTRICULAR TACHYCARDIA4
SUDDEN DEATH4
SMOOTH MUSCLE ANTIBODY POSITIVE4
SKIN DISCOLOURATION4
RASH PRURITIC4
PURPURA4
PULMONARY CONGESTION4
POST PROCEDURAL COMPLICATION4
PNEUMONIA ASPIRATION4
PLATELET COUNT INCREASED4
PAROSMIA4
OXYGEN SATURATION DECREASED4
OVERDOSE4
OCCULT BLOOD POSITIVE4
MUSCULOSKELETAL STIFFNESS4
MUSCLE TWITCHING4
MENTAL IMPAIRMENT4
LUNG DISORDER4
LOW DENSITY LIPOPROTEIN INCREASED4
LIVER INJURY4
LABORATORY TEST ABNORMAL4
JAUNDICE CHOLESTATIC4
HYPOPHAGIA4
HYPERKALAEMIA4
HEPATITIS CHOLESTATIC4
HEPATIC FIBROSIS4
HEAD INJURY4
HALLUCINATION, VISUAL4
GASTROOESOPHAGEAL REFLUX DISEASE4
GASTROENTERITIS4
GASTRITIS4
FLUID RETENTION4
FLATULENCE4
FLANK PAIN4
FACIAL PALSY4
ESCHERICHIA URINARY TRACT INFECTION4
ENCEPHALOPATHY4
EMOTIONAL DISTRESS4
ELECTROCARDIOGRAM QT PROLONGED4
ELECTROCARDIOGRAM QT CORRECTED INTERVAL PROLONGED4
ELECTROCARDIOGRAM ABNORMAL4
DYSPEPSIA4
DYSGRAPHIA4
DYSARTHRIA4
DRUG HYPERSENSITIVITY4
DELIRIUM4
CORONARY ARTERY DISEASE4
CHRONIC OBSTRUCTIVE PULMONARY DISEASE4
CHOLANGITIS4
CEREBROVASCULAR ACCIDENT4
CATHETER SEPSIS4
CARDIOMYOPATHY4
CARDIOMEGALY4
BLOOD BILIRUBIN UNCONJUGATED INCREASED4
BLISTER4
AUTOIMMUNE DISORDER4
ASTHMA4
ANURIA4
ABDOMINAL SYMPTOM4
VITREOUS FLOATERS3
VISUAL FIELD DEFECT3
VASCULITIS3
TUNNEL VISION3
TORSADE DE POINTES3
TINNITUS3
TEMPORAL ARTERITIS3
SYSTEMIC LUPUS ERYTHEMATOSUS3
STRABISMUS3
STOMACH DISCOMFORT3
STAPHYLOCOCCAL SEPSIS3
SCAR3
RHONCHI3
RETINOPATHY3
RESPIRATORY TRACT INFECTION3
RENAL CYST3
REFUSAL OF TREATMENT BY PATIENT3
RECTAL HAEMORRHAGE3
READING DISORDER3
RASH MACULO-PAPULAR3
PULSE ABSENT3
PROTHROMBIN TIME SHORTENED3
POST PROCEDURAL HAEMORRHAGE3
PORTAL HYPERTENSION3
PHOTOSENSITIVITY REACTION3
PHARYNGITIS3
PHARYNGEAL OEDEMA3
PERICARDITIS3
PATHOGEN RESISTANCE3
PANCREATIC ENZYMES INCREASED3
PALLOR3
ORAL PAIN3
ORAL INTAKE REDUCED3
OLIGURIA3
NIGHT SWEATS3
NEPHROPATHY TOXIC3
NASOPHARYNGITIS3
MYOSITIS3
MYASTHENIA GRAVIS CRISIS3
MUSCULOSKELETAL CHEST PAIN3
MUSCLE INJURY3
MIGRAINE3
MASTICATION DISORDER3
MALNUTRITION3
LYMPHOCYTE COUNT INCREASED3
LYMPHOCYTE COUNT DECREASED3
LUNG INFILTRATION3
LIVER TRANSPLANT REJECTION3
LIVER TRANSPLANT3
INTERNATIONAL NORMALISED RATIO ABNORMAL3
INFECTION3
IMMUNE SYSTEM DISORDER3
HYPOALBUMINAEMIA3
HOT FLUSH3
HEPATITIS VIRAL3
HEPATITIS B3
HEPATIC LESION3
HEPATIC CYST3
HEMIPARESIS3
HEART RATE DECREASED3
HEARING IMPAIRED3
HAEMORRHAGE INTRACRANIAL3
HAEMOPTYSIS3
HAEMOLYTIC ANAEMIA3
HAEMATOCRIT INCREASED3
HAEMANGIOMA OF LIVER3
GLYCOSYLATED HAEMOGLOBIN INCREASED3
GENERALISED ERYTHEMA3
GASTROINTESTINAL HAEMORRHAGE3
GASTRIC DISORDER3
FIBROMYALGIA3
FEELING COLD3
FACIAL PAIN3
EYE DISORDER3
EXTRASYSTOLES3
ERYTHEMA NODOSUM3
EPILEPSY3
EATING DISORDER3
DYSSTASIA3
DYSAESTHESIA3
DIABETES MELLITUS3
DEEP VEIN THROMBOSIS3
DECUBITUS ULCER3
CYANOSIS3
CRYPTOGENIC CIRRHOSIS3
COORDINATION ABNORMAL3
COGNITIVE DISORDER3
CHRONIC HEPATITIS3
CHOLECYSTITIS CHRONIC3
CHANGE OF BOWEL HABIT3
BRAIN NATRIURETIC PEPTIDE INCREASED3
BONE PAIN3
BLOOD URINE PRESENT3
BLOOD UREA DECREASED3
BLOOD TRIGLYCERIDES INCREASED3
BLOOD CALCIUM DECREASED3
BILIARY CIRRHOSIS3
ASPIRATION3
APNOEA3
APLASTIC ANAEMIA3
ANTIMITOCHONDRIAL ANTIBODY POSITIVE3
AGRANULOCYTOSIS3
ACUTE MYOCARDIAL INFARCTION3
ABNORMAL SENSATION IN EYE3
VOCAL CORD PARESIS2
VOCAL CORD DISORDER2
VITH NERVE PARALYSIS2
VENTRICULAR HYPERTROPHY2
UPPER GASTROINTESTINAL HAEMORRHAGE2
UNRESPONSIVE TO VERBAL STIMULI2
UNRESPONSIVE TO STIMULI2
TONGUE DISORDER2
TONGUE BLACK HAIRY2
THROMBOSIS2
TENDERNESS2
STRIDOR2
STARING2
SPHINCTER OF ODDI DYSFUNCTION2
SKIN LACERATION2
SKIN EXFOLIATION2
SKIN DISORDER2
SELF-MEDICATION2
RIB FRACTURE2
RETINAL VEIN OCCLUSION2
RETINAL OEDEMA2
RETINAL DISORDER2
RESTLESSNESS2
RENAL TUBULAR NECROSIS2
RENAL PAIN2
RENAL DISORDER2
RED BLOOD CELL COUNT INCREASED2
RASH PAPULAR2
RASH MACULAR2
PUPILS UNEQUAL2
PULMONARY FUNCTION TEST DECREASED2
PULMONARY EMBOLISM2
PSYCHOTIC DISORDER2
PSYCHOMOTOR HYPERACTIVITY2
PSEUDOMEMBRANOUS COLITIS2
PROTEIN TOTAL DECREASED2
PRESYNCOPE2
POLYARTHRITIS2
PHARMACEUTICAL PRODUCT COMPLAINT2
PERITONITIS2
PERICARDIAL HAEMORRHAGE2
PANCREATITIS ACUTE2
PAIN OF SKIN2
OROPHARYNGEAL SWELLING2
OROPHARYNGEAL PAIN2
ORAL MUCOSAL BLISTERING2
OFF LABEL USE2
OBSTRUCTIVE AIRWAYS DISORDER2
NUCHAL RIGIDITY2
NOCTURIA2
NEUTROPHIL COUNT INCREASED2
NEUROLOGICAL SYMPTOM2
NEPHRITIS ALLERGIC2
NECROSIS ISCHAEMIC2
NECK PAIN2
MYOCARDITIS2
MYELODYSPLASTIC SYNDROME2
MYELITIS2
MUSCLE HAEMORRHAGE2
MUSCLE DISORDER2
MUSCLE CRAMP2
MUSCLE CONTRACTURE2
MULTIPLE SCLEROSIS2
MOVEMENT DISORDER2
MOTOR DYSFUNCTION2
MONOCYTE COUNT INCREASED2
MOBILITY DECREASED2
MIOSIS2
METABOLIC ENCEPHALOPATHY2
METABOLIC DISORDER2
MEMORY IMPAIRMENT2
MELAENA2
MASS2
MANIA2
MACULAR OEDEMA2
LYMPHOCYTE MORPHOLOGY ABNORMAL2
LISTLESS2
LEUKOCYTOCLASTIC VASCULITIS2
LACERATION2
KLEBSIELLA INFECTION2
ISCHAEMIA2
IRON DEFICIENCY ANAEMIA2
IRON BINDING CAPACITY TOTAL DECREASED2
INTRAOCULAR PRESSURE INCREASED2
INTESTINAL PERFORATION2
INFLUENZA2
IMMUNOLOGY TEST ABNORMAL2
IMMUNOGLOBULINS INCREASED2
ILL-DEFINED DISORDER2
ILEUS2
HYPOXIA2
HYPOKINESIA2
HYPOGLYCAEMIC COMA2
HYPOCOAGULABLE STATE2
HYPOCALCAEMIA2
HYPOAESTHESIA ORAL2
HYPOAESTHESIA FACIAL2
HYPOACUSIS2
HUMERUS FRACTURE2
HIGH DENSITY LIPOPROTEIN INCREASED2
HIGH DENSITY LIPOPROTEIN DECREASED2
HERPES ZOSTER2
HEPATORENAL SYNDROME2
HEPATITIS C ANTIBODY POSITIVE2
HEPATIC PAIN2
HEPATIC CONGESTION2
HEMIPLEGIA2
HALO VISION2
HALLUCINATION, AUDITORY2
HAEMOLYSIS2
HAEMOGLOBIN INCREASED2
HAEMODIALYSIS2
GRAND MAL CONVULSION2
GASTRIC ULCER HAEMORRHAGE2
GASTRIC ULCER2
GALLBLADDER OPERATION2
GALLBLADDER ENLARGEMENT2
GALLBLADDER CHOLESTEROLOSIS2
FREQUENT BOWEL MOVEMENTS2
FORMICATION2
FOOD INTOLERANCE2
FLUID OVERLOAD2
FEELING DRUNK2
EYE MOVEMENT DISORDER2
EYE INFLAMMATION2
ERYTHEMA MULTIFORME2
EROSIVE OESOPHAGITIS2
EPSTEIN-BARR VIRUS ANTIBODY POSITIVE2
EOSINOPHIL PERCENTAGE INCREASED2
ENTEROCOLITIS2
ENDOCARDITIS2
ELECTROMECHANICAL DISSOCIATION2
ELECTROCARDIOGRAM P WAVE ABNORMAL2
DYSPNOEA EXACERBATED2
DYSPHONIA2
DUODENAL ULCER PERFORATION2
DRY MOUTH2
Drug-induced liver injury2
DRUG PRESCRIBING ERROR2
DRUG LEVEL INCREASED2
DRUG INTOLERANCE2
DISCOMFORT2
DILATATION VENTRICULAR2
DIFFICULTY IN WALKING2
DIARRHOEA HAEMORRHAGIC2
DIABETES MELLITUS INSULIN-DEPENDENT2
DERMATITIS BULLOUS2
DEPRESSION2
DEAFNESS2
CYTOMEGALOVIRUS HEPATITIS2
CYTOMEGALOVIRUS ANTIBODY POSITIVE2
CYCLOPLEGIA2
CRYPTOGENIC ORGANIZING PNEUMONIA2
COXSACKIE VIRAL INFECTION2
CONGESTIVE CARDIOMYOPATHY2
COLON GANGRENE2
COLITIS2
CLOSTRIDIUM COLITIS2
CHRONIC HEPATIC FAILURE2
CHOKING2
CHAPPED LIPS2
CEREBRAL ISCHAEMIA2
CARDIAC TAMPONADE2
CARBON DIOXIDE DECREASED2
BURNING SENSATION2
BUNDLE BRANCH BLOCK RIGHT2
BRONCHOSPASM2
BRONCHOPNEUMONIA2
BREATH SOUNDS ABNORMAL2
BONE MARROW FAILURE2
BONE MARROW DEPRESSION2
BODY TEMPERATURE DECREASED2
BLOOD PRESSURE SYSTOLIC INCREASED2
BLOOD PH DECREASED2
BLOOD IMMUNOGLOBULIN E INCREASED2
BLOOD IMMUNOGLOBULIN A INCREASED2
BLOOD CREATININE DECREASED2
BLOOD CREATINE PHOSPHOKINASE MB INCREASED2
BIOPSY LIVER ABNORMAL2
BILIARY TRACT DISORDER2
BILIARY CIRRHOSIS PRIMARY2
BARRETT'S OESOPHAGUS2
BACTERIAL INFECTION2
BACTERIA SPUTUM IDENTIFIED2
AZOTAEMIA2
ATRIOVENTRICULAR BLOCK2
APHTHOUS STOMATITIS2
AORTIC ANEURYSM RUPTURE2
ANTINUCLEAR ANTIBODY INCREASED2
ANOXIC ENCEPHALOPATHY2
ANGIOPATHY2
ANGINA PECTORIS2
AMAUROSIS FUGAX2
AMAUROSIS2
ALPHA 1 FOETOPROTEIN INCREASED2
ALOPECIA2
ALCOHOLISM2
AGITATION2
ACUTE RESPIRATORY FAILURE2
ACUTE PRERENAL FAILURE2
ABORTION SPONTANEOUS2
ABORTION INDUCED2
YERSINIA INFECTION1
XEROPHTHALMIA1
WOUND INFECTION STAPHYLOCOCCAL1
WAIST CIRCUMFERENCE INCREASED1
VITREOUS DETACHMENT1
VISUAL PATHWAY DISORDER1
VISUAL ACUITY TESTS ABNORMAL1
VIRAL MYOCARDITIS1
VIRAL LOAD INCREASED1
VIRAEMIA1
VIITH NERVE PARALYSIS1
Ventricular hypokinesia1
Ventricular arrhythmia1
VEIN DISORDER1
VASCULAR PURPURA1
VASCULAR CALCIFICATION1
VARICOSE VEIN1
VAGINAL SWELLING1
VAGINAL HAEMORRHAGE1
UVEITIS1
URTICARIA CHRONIC1
URINE PHOSPHATE INCREASED1
URINE BILIRUBIN INCREASED1
URINE ANALYSIS ABNORMAL1
URINARY TRACT INFECTION ENTEROCOCCAL1
URINARY INCONTINENCE1
UNRESPONSIVE TO PAIN STIMULI1
ULTRASOUND ABDOMEN ABNORMAL1
ULCER1
TYPE 1 DIABETES MELLITUS1
TUBULOINTERSTITIAL NEPHRITIS1
Tryptase increased1
Troponin I increased1
TRIGEMINAL NEURALGIA1
TRICHORRHEXIS1
TRAUMATIC BRAIN INJURY1
TRANSPLANT REJECTION1
TRANSFERRIN SATURATION INCREASED1
TOXICITY TO VARIOUS AGENTS1
Toothache1
TOOTH DISCOLOURATION1
TONSILLITIS1
TONGUE PARALYSIS1
TONGUE DRY1
TONGUE BITING1
THROMBOTIC THROMBOCYTOPENIC PURPURA1
THROMBOCYTHAEMIA1
THIRST DECREASED1
THERMAL BURN1
THERAPEUTIC RESPONSE INCREASED1
THERAPEUTIC RESPONSE DECREASED1
THERAPEUTIC AGENT TOXICITY1
TENSION HEADACHE1
TENDONITIS1
TENDON DISORDER1
TENDON RUPTURE1
TEARFULNESS1
TACHYARRHYTHMIA1
SYSTEMIC INFLAMMATORY RESPONSE SYNDROME1
SUNBURN1
SUFFOCATION FEELING1
SUBDURAL HAEMATOMA1
STRESS SYMPTOMS1
STREPTOCOCCAL SEPSIS1
STREPTOCOCCAL BACTERAEMIA1
STAPHYLOCOCCAL INFECTION1
STAPHYLOCOCCAL ABSCESS1
SQUAMOUS CELL CARCINOMA1
SPUTUM RETENTION1
SPUTUM DISCOLOURED1
SPINAL OSTEOARTHRITIS1
SPINAL DISORDER1
SPIDER NAEVUS1
SOPOR1
SMOOTH MUSCLE ANTIBODY1
SMALL INTESTINAL OBSTRUCTION1
SLEEP APNOEA SYNDROME1
SKIN WRINKLING1
SKIN WARM1
SKIN ULCER1
SKIN REACTION1
SKIN NECROSIS1
Skin mass1
SKIN INFECTION1
Skin burning sensation1
SKIN BACTERIAL INFECTION1
SINUSITIS BACTERIAL1
SINUS DISORDER1
SINUS BRADYCARDIA1
SINUS ARRHYTHMIA1
SINUS ARREST1
SICK SINUS SYNDROME1
SHOULDER PAIN1
SENSITIVITY OF TEETH1
SENSATION OF PRESSURE1
SENSATION OF FOREIGN BODY1
SEIZURE ANOXIC1
SCOTOMA1
SCOLIOSIS1
SCLERAL DISCOLOURATION1
ROTAVIRUS TEST POSITIVE1
RHINORRHOEA1
RHINITIS1
RHEUMATOID FACTOR POSITIVE1
RHEUMATOID FACTOR INCREASED1
RETROPERITONEAL HAEMATOMA1
RETROGRADE AMNESIA1
RETINAL HAEMORRHAGE1
RETINAL EXUDATES1
RETICULOCYTE PERCENTAGE INCREASED1
RETICULOCYTE COUNT INCREASED1
RESPIRATORY PARALYSIS1
RESPIRATORY DEPRESSION1
RESPIRATORY ALKALOSIS1
RESPIRATORY ACIDOSIS1
RESPIRATION ABNORMAL1
RENAL TUBULAR ACIDOSIS1
RENAL PAPILLARY NECROSIS1
RENAL INJURY1
RENAL HAEMORRHAGE1
REFLUX OESOPHAGITIS1
RED CELL DISTRIBUTION WIDTH INCREASED1
RED BLOOD CELL ABNORMALITY1
RALES1
RADICULITIS1
PUPILLARY REFLEX IMPAIRED1
PULSE ABNORMAL1
PULMONARY VALVE INCOMPETENCE1
PULMONARY HAEMORRHAGE1
PSYCHOTIC DISORDER DUE TO A GENERAL MEDICAL CONDITION1
PRURITUS GENERALISED1
PRURIGO1
PROTHROMBIN TIME RATIO INCREASED1
PROTEIN TOTAL INCREASED1
PRODUCTIVE COUGH1
PROCEDURAL PAIN1
PRESBYOPIA1
PREGNANCY1
POST-TRAUMATIC STRESS DISORDER1
POST PROCEDURAL VOMITING1
POST PROCEDURAL HAEMATOMA1
PORTAL VEIN THROMBOSIS1
PORTAL TRIADITIS1
POOR QUALITY DRUG ADMINISTERED1
POLYURIA1
POLYNEUROPATHY1
POLYMYOSITIS1
POIKILOCYTOSIS1
PO2 INCREASED1
PO2 DECREASED1
PNEUMOTHORAX1
PNEUMONITIS1
PNEUMONIA STAPHYLOCOCCAL1
PNEUMONIA MYCOPLASMAL1
PLEURITIC PAIN1
PLEURISY1
PLEURAL HAEMORRHAGE1
PLEURAL DISORDER1
PLASMAPHERESIS1
PLASMA CELLS INCREASED1
PITUITARY TUMOUR BENIGN1
PHOTODERMATOSIS1
PHLEBITIS1
PHARYNGEAL LESION1
PHARYNGEAL ERYTHEMA1
PHARYNGEAL DISORDER1
PERTUSSIS1
PERSONALITY DISORDER1
PERITONEAL HAEMORRHAGE1
PERIPHERAL PARALYSIS1
PERIPHERAL NERVE OPERATION1
PERIPHERAL ISCHAEMIA1
PERIORBITAL OEDEMA1
PELVIC INFLAMMATORY DISEASE1
PELVIC FLUID COLLECTION1
PCO2 INCREASED1
PARESIS CRANIAL NERVE1
Paresis1
PARANOIA1
PAPILLOEDEMA1
PANIC ATTACK1
PANCREATITIS CHRONIC1
PANCREATIC ENLARGEMENT1
PANCREATIC DUCT OBSTRUCTION1
PANCREAS LIPOMATOSIS1
PALMAR ERYTHEMA1
PAINFUL RESPIRATION1
OSTEOMYELITIS1
ORTHOSTATIC HYPOTENSION1
ORAL PRURITUS1
ORAL MUCOSAL HYPERTROPHY1
ORAL MUCOSAL ERUPTION1
ORAL DISCOMFORT1
OPTIC NEURITIS RETROBULBAR1
OPTIC NEURITIS1
OPHTHALMOLOGICAL EXAMINATION ABNORMAL1
ONYCHOMADESIS1
OESOPHAGITIS1
OESOPHAGEAL VARICES HAEMORRHAGE1
OESOPHAGEAL SPASM1
OESOPHAGEAL HAEMORRHAGE1
OEDEMA MOUTH1
NUCLEAR MAGNETIC RESONANCE IMAGING ABNORMAL1
NON-HODGKIN'S LYMPHOMA1
NODAL RHYTHM1
NEUTROPHILIA1
NEUTROPHIL PERCENTAGE INCREASED1
NEUROTOXICITY1
NEURODERMATITIS1
NEURALGIA1
NEPHROLITHIASIS1
NEOPLASM MALIGNANT1
NECROSIS1
NECK INJURY1
NASAL SEPTUM DEVIATION1
NASAL DISCOMFORT1
NASAL CONGESTION1
MYOPIA1
MYOCLONUS1
MYCOPLASMA SEROLOGY POSITIVE1
MUSCULOSKELETAL PAIN1
MUSCLE RIGIDITY1
MULTIPLE DRUG OVERDOSE1
MUCOUS MEMBRANE DISORDER1
MUCOSAL MEMBRANE HYPERPLASIA1
MUCOSAL INFLAMMATION1
MOUTH ULCERATION1
MONONUCLEOSIS HETEROPHILE TEST POSITIVE1
MONOCYTE COUNT ABNORMAL1
MIGRAINE WITH AURA1
MICTURITION URGENCY1
MICROCYTOSIS1
METASTASES TO LYMPH NODES1
METAMORPHOPSIA1
MENINGITIS PNEUMOCOCCAL1
MEGACOLON1
MECHANICAL VENTILATION1
MEAN PLATELET VOLUME DECREASED1
MEAN CELL VOLUME INCREASED1
MATERNAL DRUGS AFFECTING FOETUS1
MASTOIDITIS1
MARKEDLY REDUCED DIETARY INTAKE1
MANTLE CELL LYMPHOMA1
MALARIA1
MADAROSIS1
MACULOPATHY1
MACULAR DEGENERATION1
MACROCYTOSIS1
LYMPHOID TISSUE HYPERPLASIA1
LYMPHOCYTIC INFILTRATION1
LYMPHOCYTE STIMULATION TEST POSITIVE1
LYMPHOCYTE PERCENTAGE DECREASED1
LYMPHADENITIS1
LYME DISEASE1
LUNG NEOPLASM MALIGNANT1
LUNG NEOPLASM1
Lower respiratory tract infection1
LONG QT SYNDROME1
LOEFFLER'S SYNDROME1
LOCALISED OEDEMA1
LOCAL SWELLING1
LOBAR PNEUMONIA1
LIVER OPERATION1
LIVER ABSCESS1
LIPASE ABNORMAL1
LIP SWELLING1
LIP OEDEMA1
LIMB INJURY1
LIGHT CHAIN ANALYSIS INCREASED1
LEUKOCYTURIA1
LEG AMPUTATION1
LEFT VENTRICULAR FAILURE1
LEFT VENTRICULAR DYSFUNCTION1
LARYNGOPHARYNGITIS1
LACTOBACILLUS INFECTION1
LACTIC ACIDOSIS1
Kounis syndrome1
KERATOACANTHOMA1
JOINT INJURY1
ISCHAEMIC CARDIOMYOPATHY1
IRRITABILITY1
INTUBATION COMPLICATION1
INTUBATION1
INTRACARDIAC THROMBUS1
INTRA-UTERINE DEATH1
INTESTINAL SPASM1
INTESTINAL RESECTION1
INTESTINAL OBSTRUCTION1
INTENTIONAL DRUG MISUSE1
INJURY ASPHYXIATION1
INFECTIOUS MONONUCLEOSIS1
INCORRECT DOSE ADMINISTERED1
INCONTINENCE1
INCOHERENT1
INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION1
IMPETIGO1
IMPAIRED HEALING1
IMPAIRED GASTRIC EMPTYING1
IMMUNOSUPPRESSION1
ILEITIS1
IIIRD NERVE DISORDER1
HYPOVITAMINOSIS1
HYPOTONIA1
HYPOTHERMIA1
HYPOSMIA1
HYPOREFLEXIA1
HYPOPROTHROMBINAEMIA1
HYPOPROTEINAEMIA1
HYPOPHOSPHATAEMIA1
HYPOCHLORAEMIA1
HYPERVOLAEMIA1
HYPERVENTILATION1
HYPERURICAEMIA1
HYPERTRIGLYCERIDAEMIA1
HYPERTRANSAMINASAEMIA1
HYPERSOMNIA1
HYPERPYREXIA1
HYPERPHOSPHATAEMIA1
HYPERLIPIDAEMIA1
HYPERKINESIA1
HYPERGAMMAGLOBULINAEMIA1
HYPERBILIRUBINAEMIA1
HYPERAEMIA1
HYPERACUSIS1
HYDROTHORAX1
HOSPITALISATION1
HICCUPS1
HIATUS HERNIA1
HERNIA1
HEPATOSPLENOMEGALY1
Hepatocellular injury1
HEPATOBILIARY SCAN ABNORMAL1
HEPATITIS CHRONIC ACTIVE1
HEPATITIS C1
HEPATITIS B VIRUS TEST1
HEPATITIS B SURFACE ANTIGEN POSITIVE1
HEPATITIS B CORE ANTIGEN POSITIVE1
HEPATITIS A ANTIBODY POSITIVE1
HEPATITIS A1
HEPATIC VEIN OCCLUSION1
HEPATIC NEOPLASM MALIGNANT1
HEPATIC NEOPLASM1
HEPATIC MASS1
HEPATIC INFARCTION1
HEPATIC HAEMORRHAGE1
HEPATIC ENZYME ABNORMAL1
HEPATIC ATROPHY1
HEPATIC ARTERY THROMBOSIS1
HENOCH-SCHONLEIN PURPURA1
HELICOBACTER GASTRITIS1
HEART RATE ABNORMAL1
HEART INJURY1
HAPTOGLOBIN INCREASED1
HAPTOGLOBIN DECREASED1
HAEMOPNEUMOTHORAX1
HAEMOCHROMATOSIS1
HAEMATOMA1
HAEMARTHROSIS1
GRAM STAIN POSITIVE1
GLYCOSYLATED HAEMOGLOBIN DECREASED1
GLOSSITIS1
GLOMERULONEPHRITIS1
GLOMERULAR FILTRATION RATE DECREASED1
GLOBULINS INCREASED1
GINGIVAL HYPERTROPHY1
GENITAL LESION1
GENITAL HAEMORRHAGE1
GENERAL PHYSICAL CONDITION ABNORMAL1
GENE MUTATION1
GASTROINTESTINAL TUBE INSERTION1
GASTROINTESTINAL PAIN1
GASTROINTESTINAL NECROSIS1
GASTROINTESTINAL INJURY1
GASTROINTESTINAL INFLAMMATION1
GASTRIC ULCER PERFORATION1
GASTRIC CANCER1
GANGRENE1
GAMMOPATHY1
GAMMA-GLUTAMYLTRANSFERASE1
GALLBLADDER OEDEMA1
FUSOBACTERIUM INFECTION1
FUNGAL SKIN INFECTION1
FUNGAL INFECTION1
FRACTURE1
FOOD AVERSION1
FOOD ALLERGY1
FIBRINOLYSIS INCREASED1
FIBRINOLYSIS ABNORMAL1
FEBRILE CONVULSION1
FEAR OF FALLING1
FANCONI SYNDROME1
FAECES HARD1
FAECAL VOLUME DECREASED1
FAECAL INCONTINENCE1
Facial paralysis1
FACIAL BONES FRACTURE1
EYELID PTOSIS1
EYELID OEDEMA1
EYELID DISORDER1
EYE SWELLING1
EYE PRURITUS1
EYE OPERATION1
EYE INJURY1
EYE INFECTION FUNGAL1
EYE HAEMORRHAGE1
EXTREMITY NECROSIS1
EXTRAPYRAMIDAL DISORDER1
EXTRAOCULAR MUSCLE PARESIS1
Expired product administered1
EUPHORIC MOOD1
ESCHERICHIA SEPSIS1
ESCHERICHIA INFECTION1
ERUCTATION1
EPSTEIN-BARR VIRUS ANTIGEN POSITIVE1
EPIGASTRIC DISCOMFORT1
EOSINOPHILIC PNEUMONIA CHRONIC1
EOSINOPHILIC PNEUMONIA1
ENTEROCOLITIS INFECTIOUS1
ENTEROCOLITIS HAEMORRHAGIC1
ENDOTRACHEAL INTUBATION1
ENCEPHALITIS HERPES1
ENCEPHALITIS1
EMPYEMA1
EMPTY SELLA SYNDROME1
EMOTIONAL DISORDER1
EMBOLISM1
ELECTROLYTE IMBALANCE1
ELECTROCARDIOGRAM T WAVE INVERSION1
ELECTROCARDIOGRAM T WAVE ABNORMAL1
Electrocardiogram ST segment elevation1
ELECTROCARDIOGRAM ST SEGMENT DEPRESSION1
ELECTROCARDIOGRAM QT INTERVAL1
ELECTROCARDIOGRAM QRS COMPLEX PROLONGED1
ELECTROCARDIOGRAM PR PROLONGATION1
ELECTROCARDIOGRAM POOR R-WAVE PROGRESSION1
ELECTROCARDIOGRAM CHANGE1
ECZEMA1
ECTOPIC PREGNANCY1
ECHOCARDIOGRAM ABNORMAL1
ECCHYMOSIS1
Ear pain1
EAR DISCOMFORT1
DYSPNOEA AT REST1
DYSCALCULIA1
DRY SKIN1
DRY EYE1
Drug reaction with eosinophilia and systemic symptoms1
DRUG RASH WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS1
DRUG LEVEL CHANGED1
DRUG EFFECT PROLONGED1
DRUG DOSE OMISSION1
DRUG ABUSER1
DRUG ADMINISTRATION ERROR1
DROOLING1
DOUBLE STRANDED DNA ANTIBODY1
DIVERTICULUM1
DISEASE PROGRESSION1
DIRECTIONAL DOPPLER FLOW TESTS ABNORMAL1
DILATATION ATRIAL1
DIASTOLIC DYSFUNCTION1
DIABETES MELLITUS INADEQUATE CONTROL1
DERMATOMYOSITIS1
DERMATITIS EXFOLIATIVE1
DERMATITIS CONTACT1
DERMATITIS ALLERGIC1
DERMATITIS ACNEIFORM1
DERMATITIS1
DENTAL PLAQUE1
DENTAL CARIES1
DEMENTIA ALZHEIMER'S TYPE1
DECREASED ACTIVITY1
DEAFNESS UNILATERAL1
DEAFNESS NEUROSENSORY1
DEAFNESS BILATERAL1
DARK CIRCLES UNDER EYES1
CYTOMEGALOVIRUS TEST1
CYTOMEGALOVIRUS INFECTION1
CYSTITIS HAEMORRHAGIC1
CSF LYMPHOCYTE COUNT INCREASED1
CRYING1
CREPITATIONS1
CREATININE RENAL CLEARANCE DECREASED1
CRANIAL NERVE PARALYSIS1
CORONARY ARTERY THROMBOSIS1
CORONARY ARTERY OCCLUSION1
CORONARY ARTERY ATHEROSCLEROSIS1
COOMBS DIRECT TEST POSITIVE1
CONGENITAL CYSTIC KIDNEY DISEASE1
CONCUSSION1
COMPULSIONS1
COMPLICATIONS OF TRANSPLANTED LIVER1
COMPLICATIONS OF TRANSPLANT SURGERY1
COMPLICATIONS OF MATERNAL EXPOSURE TO THERAPEUTIC DRUGS1
COMA HEPATIC1
COLOUR BLINDNESS ACQUIRED1
COLONIC POLYP1
COLLAGEN DISORDER1
COLECTOMY1
COLD AGGLUTININS POSITIVE1
COGWHEEL RIGIDITY1
CLOSTRIDIUM DIFFICILE COLITIS1
CLAVICLE FRACTURE1
CILIARY MUSCLE SPASM1
CHRONIC OBSTRUCTIVE AIRWAYS DISEASE EXACERBATED1
CHOLURIA1
CHOLESTATIC LIVER INJURY1
CHOLECYSTITIS ACUTE1
CHEST X-RAY ABNORMAL1
CHEILITIS1
CERULOPLASMIN DECREASED1
CEREBROVASCULAR DISORDER1
CEREBRAL VENOUS THROMBOSIS1
CEREBRAL HAEMORRHAGE1
CEREBRAL CYST1
CEREBRAL ATROPHY1
CEREBRAL ARTERY OCCLUSION1
CAUSTIC INJURY1
CATHETER PLACEMENT1
CATARACT1
CAROTID ARTERY OCCLUSION1
CARDIOTOXICITY1
CARDIOPULMONARY FAILURE1
CARDIOMYOPATHY ACUTE1
CARDIOGENIC SHOCK1
CARDIOACTIVE DRUG LEVEL INCREASED1
CARDIAC PACEMAKER MALFUNCTION1
CARDIAC FLUTTER1
CARBON DIOXIDE INCREASED1
CANDIDIASIS1
CAMPYLOBACTER INFECTION1
BURNS SECOND DEGREE1
BUNDLE BRANCH BLOCK LEFT1
BUDD-CHIARI SYNDROME1
BRONCHITIS CHRONIC1
BRONCHITIS ACUTE1
BREAST DISCHARGE1
BRAIN DAMAGE1
BRAIN ABSCESS1
BONE DISORDER1
BLOOD URINE1
BLOOD URIC ACID INCREASED1
BLOOD PRESSURE INADEQUATELY CONTROLLED1
BLOOD PRESSURE FLUCTUATION1
BLOOD PRESSURE DIASTOLIC INCREASED1
BLOOD PRESSURE DIASTOLIC DECREASED1
BLOOD POTASSIUM INCREASED1
BLOOD PHOSPHORUS INCREASED1
BLOOD MAGNESIUM INCREASED1
BLOOD IRON DECREASED1
BLOOD IMMUNOGLOBULIN M INCREASED1
BLOOD GLUCOSE DECREASED1
BLOOD FIBRINOGEN INCREASED1
BLOOD FIBRINOGEN DECREASED1
BLOOD DISORDER1
BLOOD CULTURE POSITIVE1
Blood creatine phosphokinase MB1
BLOOD CHOLESTEROL DECREASED1
BLOOD CHLORIDE INCREASED1
BLOOD CALCIUM INCREASED1
BLOOD BILIRUBIN ABNORMAL1
BLOOD ALKALINE PHOSPHATASE DECREASED1
BLOOD ALKALINE PHOSPHATASE1
BLOOD ALBUMIN INCREASED1
BLEEDING VARICOSE VEIN1
BILIRUBINURIA1
BILIARY DILATATION1
BILIARY CYST1
BILIARY COLIC1
BILE OUTPUT1
BILE DUCT STENOSIS1
BILE DUCT OBSTRUCTION1
BENIGN INTRACRANIAL HYPERTENSION1
BEDRIDDEN1
BACTERIA URINE IDENTIFIED1
BACTERIA BLOOD IDENTIFIED1
AURICULAR SWELLING1
AURA1
ATRIOVENTRICULAR BLOCK SECOND DEGREE1
ATRIAL THROMBOSIS1
ATOPY1
ATAXIA1
ASPHYXIA1
ARTHROPATHY1
ARTHRITIS BACTERIAL1
ARTHRITIS1
ARTERIOSCLEROSIS1
APPETITE DISORDER1
APPENDIX DISORDER1
APHONIA1
APALLIC SYNDROME1
AORTIC VALVE SCLEROSIS1
AORTIC VALVE DISEASE1
ANXIETY DISORDER1
ANTIPSYCHOTIC DRUG LEVEL ABOVE THERAPEUTIC1
ANTIMITOCHONDRIAL ANTIBODY1
ANTIBODY TEST POSITIVE1
ANTI-HBE ANTIBODY POSITIVE1
ANOXIA1
ANKLE FRACTURE1
ANISOCYTOSIS1
ANION GAP INCREASED1
Angle closure glaucoma1
ANGIOTENSIN CONVERTING ENZYME INCREASED1
ANGER1
ANAEMIA OF CHRONIC DISEASE1
AMPUTATION1
AMPHETAMINES POSITIVE1
AMMONIA1
AMENORRHOEA1
AMBLYOPIA1
ALTERED VISUAL DEPTH PERCEPTION1
ALTERED STATE OF CONSCIOUSNESS1
ALPHA 2 GLOBULIN INCREASED1
ALCOHOLIC1
ALBUMIN URINE1
AGORAPHOBIA1
ADVERSE EVENT1
ADRENAL ADENOMA1
ADENOMYOSIS1
ADENOMA BENIGN1
ACUTE TONSILLITIS1
ACUTE MYELOID LEUKAEMIA1
ACTINIC KERATOSIS1
ACNE1
ACARODERMATITIS1
ABSCESS1
ABNORMAL DREAMS1
ABNORMAL BEHAVIOUR1





Toxicity information:

Toxicity type: N/A



External links:

ChEBML: CHEMBL1136
DrugBank: DB00976