sildenafil

General information:

Withdrawn ID:	EMA39
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es):	G04BE03
Molecular Formula:	C22H30N6O4S
Molweight:	474.576

Withdrawal information:

Withdrawn due to drug safety reasons:	No

Side-effects:

Total reported cases (submitted by medical professionals) with sildenafil as primary suspect:	11136

Reported final outcomes:

Hospitalization (initial or prolonged):	2602
Death:	2526
Life-Threatening condition:	335
Disability:	274
Intervention required to prevent permanent impairment/damage:	40
Congenital anomaly:	6

Reported side-effects:

Side-effect	Case number
DRUG INEFFECTIVE	1451
DEATH	1281
MALIGNANT MELANOMA	950
DYSPNOEA	482
HEADACHE	450
OFF LABEL USE	429
Product use issue	391
PULMONARY HYPERTENSION	365
OPTIC ISCHAEMIC NEUROPATHY	341
CONDITION AGGRAVATED	326
HYPOTENSION	322
MALAISE	265
BLINDNESS	262
Malignant melanoma in situ	261
PNEUMONIA	221
VISION BLURRED	216
DIZZINESS	210
CARDIAC FAILURE	201
DRUG INTERACTION	188
ANXIETY	179
FLUSHING	176
FALL	173
CHEST PAIN	163
Visual impairment	159
NAUSEA	153
CEREBROVASCULAR ACCIDENT	153
CARDIAC FAILURE CONGESTIVE	153
FATIGUE	149
SYNCOPE	147
MYOCARDIAL INFARCTION	138
BLINDNESS UNILATERAL	135
RIGHT VENTRICULAR FAILURE	132
HYPERTENSION	132
CARDIAC ARREST	131
RESPIRATORY FAILURE	129
DIARRHOEA	126
COUGH	120
VOMITING	119
ATRIAL FIBRILLATION	119
NASAL CONGESTION	112
PULMONARY ARTERIAL HYPERTENSION	111
VISUAL ACUITY REDUCED	109
DEPRESSION	109
Product use in unapproved indication	107
DISEASE PROGRESSION	106
Intentional product misuse	105
PULMONARY OEDEMA	104
CARDIAC DISORDER	104
FLUID RETENTION	102
ASTHENIA	102
RENAL FAILURE	100
BLOOD PRESSURE DECREASED	100
PALPITATIONS	99
OEDEMA PERIPHERAL	99
LOSS OF CONSCIOUSNESS	99
VISUAL FIELD DEFECT	96
PAIN	93
DEAFNESS	93
CYANOPSIA	92
BACK PAIN	90
WEIGHT DECREASED	89
PYREXIA	85
PRODUCT QUALITY ISSUE	84
DRUG EFFECT DECREASED	84
NASOPHARYNGITIS	83
Metastatic malignant melanoma	83
Intentional product use issue	83
OXYGEN SATURATION DECREASED	81
HOSPITALISATION	80
FEELING ABNORMAL	80
ANAEMIA	79
THERAPEUTIC RESPONSE UNEXPECTED	78
HYPOXIA	78
OVERDOSE	76
DRUG INEFFECTIVE FOR UNAPPROVED INDICATION	76
DRUG ABUSE	75
Emotional distress	74
PROSTATE CANCER	73
EPISTAXIS	73
SEPSIS	72
Drug effect incomplete	72
CHRONIC OBSTRUCTIVE PULMONARY DISEASE	72
ERECTILE DYSFUNCTION	71
DRUG HYPERSENSITIVITY	71
PRIAPISM	70
HEART RATE INCREASED	69
ACUTE MYOCARDIAL INFARCTION	69
TACHYCARDIA	67
ERECTION INCREASED	66
DYSPEPSIA	66
GAIT DISTURBANCE	65
PAIN IN EXTREMITY	64
Prescribed overdose	63
HYPOACUSIS	63
RETINAL VEIN OCCLUSION	61
INFLUENZA	60
PLEURAL EFFUSION	59
CEREBRAL HAEMORRHAGE	59
RASH	58
INSOMNIA	58
HAEMORRHAGE	58
CATARACT	58
BLOOD PRESSURE INCREASED	58
TINNITUS	56
MYALGIA	56
ARRHYTHMIA	56
WEIGHT INCREASED	54
INCORRECT DOSE ADMINISTERED	54
CARDIO-RESPIRATORY ARREST	54
ABDOMINAL PAIN	54
Pre-existing condition improved	53
OEDEMA	53
CONFUSIONAL STATE	53
CHEST DISCOMFORT	53
ARTHRALGIA	53
Peripheral swelling	52
MEMORY IMPAIRMENT	51
Malignant melanoma stage IV	50
GASTROINTESTINAL HAEMORRHAGE	49
DIABETES MELLITUS	49
INFECTION	48
INTENTIONAL OVERDOSE	47
HYPERHIDROSIS	47
VENTRICULAR FIBRILLATION	45
ERYTHEMA	45
ABDOMINAL PAIN UPPER	45
ABDOMINAL DISCOMFORT	45
LUNG DISORDER	44
ISCHAEMIC STROKE	44
TREMOR	43
PAPILLOEDEMA	43
GENERAL PHYSICAL HEALTH DETERIORATION	43
DECREASED APPETITE	43
Toxicity to various agents	42
RETINAL HAEMORRHAGE	42
COMA	42
BLINDNESS TRANSIENT	42
URINARY TRACT INFECTION	41
DRUG DOSE OMISSION	41
VISUAL DISTURBANCE	40
NEOPLASM MALIGNANT	40
Lentigo maligna	40
GASTROOESOPHAGEAL REFLUX DISEASE	40
FLUID OVERLOAD	40
DEHYDRATION	40
DEAFNESS UNILATERAL	40
Acute kidney injury	40
THROMBOCYTOPENIA	39
RETINAL ARTERY OCCLUSION	39
Malignant melanoma stage III	39
INTERSTITIAL LUNG DISEASE	39
Suspected counterfeit product	38
PULMONARY EMBOLISM	38
HAEMOPTYSIS	38
BRONCHITIS	38
BRADYCARDIA	38
SELF-MEDICATION	37
MUSCLE SPASMS	37
CIRCULATORY COLLAPSE	37
THROMBOSIS	36
PHOTOPHOBIA	36
EYE PAIN	36
ASCITES	36
ABDOMINAL DISTENSION	36
HYPOAESTHESIA	35
Expired product administered	35
DYSPNOEA EXERTIONAL	35
CORONARY ARTERY DISEASE	35
CHORIORETINOPATHY	35
TRANSIENT ISCHAEMIC ATTACK	34
SWELLING	34
PRURITUS	34
RHINORRHOEA	33
PULMONARY FIBROSIS	33
DRUG INTOLERANCE	33
CARDIOGENIC SHOCK	33
BLOOD CREATININE INCREASED	33
SCOTOMA	32
PARAESTHESIA	32
BLOOD GLUCOSE INCREASED	32
BLOOD CHOLESTEROL INCREASED	32
THERAPY CESSATION	31
ROAD TRAFFIC ACCIDENT	31
RESPIRATORY ARREST	31
RENAL IMPAIRMENT	31
RENAL DISORDER	31
MULTI-ORGAN FAILURE	31
HAEMOGLOBIN DECREASED	31
CEREBRAL INFARCTION	31
ANGIOEDEMA	31
AMNESIA	31
SOMNOLENCE	30
FEELING HOT	30
CONVULSION	30
BLOOD TESTOSTERONE DECREASED	30
SUDDEN DEATH	29
SCLERODERMA	29
RENAL FAILURE ACUTE	29
PULMONARY HAEMORRHAGE	29
Product dose omission	29
PLATELET COUNT DECREASED	29
Neoplasm progression	29
HOT FLUSH	29
CHILLS	29
CELLULITIS	29
BODY HEIGHT DECREASED	29
ACUTE RESPIRATORY FAILURE	29
SUBARACHNOID HAEMORRHAGE	28
STRESS	28
SINUSITIS	28
RESPIRATORY DISORDER	28
NO ADVERSE EVENT	28
Malignant melanoma stage II	28
MACULAR DEGENERATION	28
GASTROINTESTINAL DISORDER	28
DIPLOPIA	28
CYANOSIS	28
CONSTIPATION	28
VERTIGO	27
VENTRICULAR TACHYCARDIA	27
PNEUMONIA ASPIRATION	27
OCULAR HYPERAEMIA	27
HEPATIC FAILURE	27
GLAUCOMA	27
DYSPHAGIA	27
CORONARY ARTERY OCCLUSION	27
CHROMATOPSIA	27
BALANCE DISORDER	27
ARTHRITIS	27
THERAPY NON-RESPONDER	26
PRODUCTIVE COUGH	26
PERICARDIAL EFFUSION	26
OPTIC NEURITIS	26
OPTIC ATROPHY	26
MEDICATION ERROR	26
HYPERSENSITIVITY	26
HIP FRACTURE	26
HEMIPARESIS	26
COMPLETED SUICIDE	26
ASPARTATE AMINOTRANSFERASE INCREASED	26
ALANINE AMINOTRANSFERASE INCREASED	26
AGITATION	26
TREATMENT NONCOMPLIANCE	25
RETINAL DETACHMENT	25
HEPATOTOXICITY	25
EYE HAEMORRHAGE	25
Drug effective for unapproved indication	25
CARDIAC FAILURE CHRONIC	25
CARDIAC FAILURE ACUTE	25
ARTHROPATHY	25
SWELLING FACE	24
Superficial spreading melanoma stage unspecified	24
SKIN ULCER	24
RECTAL HAEMORRHAGE	24
Prescription drug used without a prescription	24
PAIN IN JAW	24
MUSCULAR WEAKNESS	24
Malignant melanoma stage I	24
MACULOPATHY	24
LIVER DISORDER	24
HEPATIC FUNCTION ABNORMAL	24
EYE DISORDER	24
CONTUSION	24
SUICIDE ATTEMPT	23
PHOTOPSIA	23
OROPHARYNGEAL PAIN	23
Maternal exposure during pregnancy	23
MACULAR OEDEMA	23
LIVER FUNCTION TEST ABNORMAL	23
DYSURIA	23
ANGINA PECTORIS	23
SPEECH DISORDER	22
PULMONARY CONGESTION	22
PRESYNCOPE	22
MIGRAINE	22
HEART RATE DECREASED	22
DRY MOUTH	22
ATRIAL FLUTTER	22
SINUS TACHYCARDIA	21
RHABDOMYOLYSIS	21
Product substitution issue	21
GENERALISED OEDEMA	21
GAMMA-GLUTAMYLTRANSFERASE INCREASED	21
DRUG DEPENDENCE	21
CHOLELITHIASIS	21
APHASIA	21
RESPIRATORY DISTRESS	20
PEYRONIE'S DISEASE	20
LOWER LIMB FRACTURE	20
INTERNATIONAL NORMALISED RATIO INCREASED	20
HEAD INJURY	20
DISORIENTATION	20
DEPRESSED LEVEL OF CONSCIOUSNESS	20
DEEP VEIN THROMBOSIS	20
URINARY RETENTION	19
SLEEP APNOEA SYNDROME	19
PNEUMOTHORAX	19
PENIS DISORDER	19
OCULAR VASCULAR DISORDER	19
LIMB INJURY	19
HAEMATURIA	19
GOUT	19
DEAFNESS NEUROSENSORY	19
BLOOD UREA INCREASED	19
WHEEZING	18
TRANSIENT GLOBAL AMNESIA	18
PULMONARY ARTERIAL PRESSURE INCREASED	18
LUNG NEOPLASM MALIGNANT	18
LACRIMATION INCREASED	18
INJURY	18
HYPERKALAEMIA	18
HEPATIC CIRRHOSIS	18
EJACULATION DISORDER	18
DYSARTHRIA	18
WOUND	17
UPPER RESPIRATORY TRACT INFECTION	17
SUDDEN CARDIAC DEATH	17
STAPHYLOCOCCAL INFECTION	17
SINUS CONGESTION	17
RETINAL DISORDER	17
PULMONARY VENO-OCCLUSIVE DISEASE	17
Product prescribing error	17
PANCYTOPENIA	17
JAUNDICE	17
FLATULENCE	17
Drug administered to patient of inappropriate age	17
CARDIOMEGALY	17
SUDDEN HEARING LOSS	16
SHOCK	16
RESPIRATORY TRACT INFECTION	16
LETHARGY	16
JOINT SWELLING	16
INTRAOCULAR PRESSURE INCREASED	16
INTENTIONAL DRUG MISUSE	16
INFLUENZA LIKE ILLNESS	16
HEPATIC ENZYME INCREASED	16
DRUG DISPENSING ERROR	16
ACUTE CORONARY SYNDROME	16
VITREOUS FLOATERS	15
SKIN DISCOLOURATION	15
SEPTIC SHOCK	15
Seizure	15
Pulseless electrical activity	15
Product dispensing error	15
POST PROCEDURAL COMPLICATION	15
NECK PAIN	15
HAEMATEMESIS	15
DYSPHONIA	15
Drug-induced liver injury	15
Drug prescribing error	15
DISEASE RECURRENCE	15
COVID-19	15
COAGULOPATHY	15
CHOLESTASIS	15
C-REACTIVE PROTEIN INCREASED	15
Basal cell carcinoma	15
ALCOHOL USE	15
ABNORMAL BEHAVIOUR	15
WHITE BLOOD CELL COUNT INCREASED	14
VIRAL INFECTION	14
Therapeutic product effect incomplete	14
Terminal state	14
SYSTEMIC LUPUS ERYTHEMATOSUS	14
SUBSTANCE ABUSE	14
SPINAL FRACTURE	14
PHARMACEUTICAL PRODUCT COMPLAINT	14
PALLOR	14
OPTIC NEUROPATHY	14
Nodular melanoma	14
Lung transplant	14
INTESTINAL ISCHAEMIA	14
HYPOKALAEMIA	14
HAEMATOCHEZIA	14
DYSGEUSIA	14
COLOUR BLINDNESS	14
COLON CANCER	14
CARDIOMYOPATHY	14
BLOOD BILIRUBIN INCREASED	14
ASTHMA	14
Wrong technique in product usage process	13
VITREOUS DETACHMENT	13
URTICARIA	13
UNRESPONSIVE TO STIMULI	13
TYPE 2 DIABETES MELLITUS	13
Treatment failure	13
RIB FRACTURE	13
Retinal toxicity	13
RENAL TUBULAR NECROSIS	13
POLLAKIURIA	13
PENILE PAIN	13
NEUROPATHY PERIPHERAL	13
NERVOUSNESS	13
MUSCULOSKELETAL DISORDER	13
Metastases to lymph nodes	13
INTESTINAL OBSTRUCTION	13
HERPES ZOSTER	13
FACE OEDEMA	13
ELECTROCARDIOGRAM ABNORMAL	13
Dyschromatopsia	13
DEVICE RELATED INFECTION	13
COGNITIVE DISORDER	13
Chronic kidney disease	13
CATHETERISATION CARDIAC	13
CARDIOVASCULAR DISORDER	13
BLOOD PRESSURE ABNORMAL	13
AORTIC ANEURYSM	13
AGGRESSION	13
VISUAL BRIGHTNESS	12
URINARY INCONTINENCE	12
UNEVALUABLE EVENT	12
SNEEZING	12
SINUS DISORDER	12
RESTLESSNESS	12
PRODUCT TASTE ABNORMAL	12
PAINFUL ERECTION	12
OSTEOARTHRITIS	12
OPTIC DISC DISORDER	12
MUSCULOSKELETAL PAIN	12
LEFT VENTRICULAR FAILURE	12
ISCHAEMIA	12
Generalised tonic-clonic seizure	12
FLANK PAIN	12
EYE SWELLING	12
DRY SKIN	12
DRUG EXPOSURE DURING PREGNANCY	12
DRUG EFFECT DELAYED	12
DIABETIC RETINOPATHY	12
Contraindicated product administered	12
BURNING SENSATION	12
BRONCHOSPASM	12
BLOOD CREATINE PHOSPHOKINASE INCREASED	12
Back disorder	12
ACUTE PULMONARY OEDEMA	12
VASODILATATION	11
SUPRAVENTRICULAR TACHYCARDIA	11
Squamous cell carcinoma	11
SKIN LESION	11
RHEUMATOID ARTHRITIS	11
OLIGURIA	11
MYOCARDIAL ISCHAEMIA	11
MUSCULOSKELETAL STIFFNESS	11
Multiple organ dysfunction syndrome	11
MOTOR DYSFUNCTION	11
MOBILITY DECREASED	11
MENTAL STATUS CHANGES	11
MENTAL DISORDER	11
HYPERGLYCAEMIA	11
HEMIPLEGIA	11
HAEMODYNAMIC INSTABILITY	11
HAEMATOMA	11
HAEMATOCRIT DECREASED	11
FOOD INTERACTION	11
EXERCISE TOLERANCE DECREASED	11
ERYTHEMA MULTIFORME	11
ENCEPHALOPATHY	11
DIALYSIS	11
CYSTITIS	11
CONCUSSION	11
BLOOD POTASSIUM DECREASED	11
ASPIRATION	11
ARTERIAL OCCLUSIVE DISEASE	11
ANKLE FRACTURE	11
ANEURYSM	11
ANAPHYLACTIC SHOCK	11
ALTERED STATE OF CONSCIOUSNESS	11
ACUTE RESPIRATORY DISTRESS SYNDROME	11
VITREOUS HAEMORRHAGE	10
UPPER LIMB FRACTURE	10
TRICUSPID VALVE INCOMPETENCE	10
SURGERY	10
SUBDURAL HAEMATOMA	10
SKIN DISORDER	10
SCAR	10
RETINAL VASCULAR OCCLUSION	10
RETINAL VASCULAR DISORDER	10
PROSTATIC SPECIFIC ANTIGEN INCREASED	10
PARALYSIS	10
OPTIC NERVE DISORDER	10
Nightmare	10
Myocarditis	10
METASTASES TO CENTRAL NERVOUS SYSTEM	10
LUNG INFECTION	10
INFLAMMATION	10
IMPAIRED DRIVING ABILITY	10
HYPOVOLAEMIA	10
HYPONATRAEMIA	10
HERNIA	10
HEARING IMPAIRED	10
HAEMORRHAGE INTRACRANIAL	10
GLYCOSYLATED HAEMOGLOBIN INCREASED	10
GLOBAL AMNESIA	10
FOOT FRACTURE	10
EJECTION FRACTION DECREASED	10
DISTURBANCE IN ATTENTION	10
DISSEMINATED INTRAVASCULAR COAGULATION	10
DEMENTIA	10
COR PULMONALE	10
CARDIAC TAMPONADE	10
CARDIAC OPERATION	10
CARDIAC MURMUR	10
Brain injury	10
BENIGN PROSTATIC HYPERPLASIA	10
ANORGASMIA	10
ABORTION SPONTANEOUS	10
WRONG TECHNIQUE IN DRUG USAGE PROCESS	9
VENTRICULAR EXTRASYSTOLES	9
TRANSAMINASES INCREASED	9
TOOTH DISORDER	9
THROAT IRRITATION	9
THERAPEUTIC RESPONSE DECREASED	9
TACHYPNOEA	9
STATUS EPILEPTICUS	9
SHOCK HAEMORRHAGIC	9
Right ventricular dilatation	9
RETINOPATHY	9
RETINITIS PIGMENTOSA	9
RETINAL VEIN THROMBOSIS	9
RETINAL ISCHAEMIA	9
PUPILLARY REFLEX IMPAIRED	9
PULMONARY ALVEOLAR HAEMORRHAGE	9
PREMATURE BABY	9
POST PROCEDURAL HAEMORRHAGE	9
PANCREATITIS	9
MUSCULOSKELETAL DISCOMFORT	9
MITRAL VALVE INCOMPETENCE	9
MELAENA	9
MANIA	9
LOWER RESPIRATORY TRACT INFECTION	9
LIP SWELLING	9
LIMB DISCOMFORT	9
LEUKOPENIA	9
LABORATORY TEST ABNORMAL	9
Keratitis	9
INTERNATIONAL NORMALISED RATIO ABNORMAL	9
INFARCTION	9
HYPERLIPIDAEMIA	9
HEART RATE IRREGULAR	9
HALLUCINATION	9
GLOMERULAR FILTRATION RATE DECREASED	9
GASTRITIS	9
GASTRIC DISORDER	9
FEELING COLD	9
Exposure during pregnancy	9
EXPIRED DRUG ADMINISTERED	9
EMPHYSEMA	9
EAR PAIN	9
DRUG ADMINISTRATION ERROR	9
DELIRIUM	9
CONJUNCTIVITIS	9
CEREBRAL HAEMATOMA	9
BUNDLE BRANCH BLOCK RIGHT	9
BRAIN NATRIURETIC PEPTIDE INCREASED	9
BONE PAIN	9
BLOOD LACTATE DEHYDROGENASE INCREASED	9
BLOOD ALKALINE PHOSPHATASE INCREASED	9
ATRIOVENTRICULAR BLOCK	9
ARTERIOSCLEROSIS CORONARY ARTERY	9
ANURIA	9
ANGIOPATHY	9
ALOPECIA	9
ABASIA	9
VENTRICULAR HYPOKINESIA	8
VENTILATION PERFUSION MISMATCH	8
TUBULOINTERSTITIAL NEPHRITIS	8
SUICIDAL IDEATION	8
Substance use disorder	8
SPINAL CORD INFARCTION	8
Rotator cuff syndrome	8
RETINOPATHY OF PREMATURITY	8
RENAL FAILURE CHRONIC	8
RAYNAUD'S PHENOMENON	8
RASH ERYTHEMATOUS	8
PULMONARY THROMBOSIS	8
PROSTATIC DISORDER	8
Product dose omission issue	8
PRODUCT COUNTERFEIT	8
Premature delivery	8
PENILE HAEMORRHAGE	8
ORTHOSTATIC HYPOTENSION	8
OBESITY	8
NEURALGIA	8
NERVOUS SYSTEM DISORDER	8
NERVE INJURY	8
NERVE COMPRESSION	8
MYOCARDIAL FIBROSIS	8
MUSCLE STRAIN	8
METABOLIC ACIDOSIS	8
Melanoma recurrent	8
LIBIDO DECREASED	8
LEFT VENTRICULAR DYSFUNCTION	8
LARYNGEAL OEDEMA	8
INTERVERTEBRAL DISC PROTRUSION	8
Internal haemorrhage	8
ILEUS	8
Herpes simplex encephalitis	8
HAEMORRHOIDS	8
HAEMORRHAGIC STROKE	8
GASTROENTERITIS	8
GASTRIC HAEMORRHAGE	8
Gallbladder disorder	8
FRACTURE OF PENIS	8
Foetal exposure during pregnancy	8
EYELID PTOSIS	8
EJACULATION FAILURE	8
EAR DISCOMFORT	8
DYSSTASIA	8
DRUG TOXICITY	8
DISCOMFORT	8
DEPRESSED MOOD	8
Deafness bilateral	8
CRYING	8
Concomitant disease aggravated	8
COLOUR BLINDNESS ACQUIRED	8
COLD SWEAT	8
CHRONIC RESPIRATORY FAILURE	8
CEREBRAL ISCHAEMIA	8
BLOOD SODIUM DECREASED	8
ARTERIOSCLEROSIS	8
ARTERIAL DISORDER	8
AORTIC STENOSIS	8
AORTIC DISSECTION	8
ALCOHOL INTERACTION	8
Actinic keratosis	8
ABNORMAL SENSATION IN EYE	8
WITHDRAWAL SYNDROME	7
Weight fluctuation	7
VENTRICULAR HYPERTROPHY	7
VENTRICULAR ARRHYTHMIA	7
UROSEPSIS	7
UPPER GASTROINTESTINAL HAEMORRHAGE	7
ULCER	7
TESTICULAR PAIN	7
SPONTANEOUS PENILE ERECTION	7
SICKLE CELL ANAEMIA WITH CRISIS	7
RETINAL TEAR	7
Retching	7
RESTLESS LEGS SYNDROME	7
RED BLOOD CELL COUNT DECREASED	7
PENILE SWELLING	7
PARTIAL SEIZURES	7
PANCREATITIS ACUTE	7
ORTHOPNOEA	7
OPTIC DISC HAEMORRHAGE	7
OESOPHAGEAL VARICES HAEMORRHAGE	7
Miosis	7
MICTURITION URGENCY	7
Metastases to lung	7
METASTASES TO LIVER	7
MENTAL IMPAIRMENT	7
Melanocytic naevus	7
Male orgasmic disorder	7
LYMPHADENOPATHY	7
LOW DENSITY LIPOPROTEIN INCREASED	7
Loss of personal independence in daily activities	7
Localised infection	7
Laryngitis	7
Lactic acidosis	7
JOINT INJURY	7
INTRA-UTERINE DEATH	7
INTERNATIONAL NORMALISED RATIO DECREASED	7
IDIOPATHIC PULMONARY FIBROSIS	7
Hypoglycaemia	7
HYPERTENSIVE CRISIS	7
HYPERCHOLESTEROLAEMIA	7
Hyperbilirubinaemia	7
Hepatocellular injury	7
Hepatic fibrosis	7
GAZE PALSY	7
Femur fracture	7
FEAR	7
FACIAL PAIN	7
FACIAL BONES FRACTURE	7
End stage renal disease	7
Electrocardiogram ST segment depression	7
Drug use disorder	7
Drug resistance	7
DIVERTICULITIS	7
DILATATION VENTRICULAR	7
Device leakage	7
DEMENTIA ALZHEIMER'S TYPE	7
DEAFNESS TRANSITORY	7
CORONARY ARTERY THROMBOSIS	7
CORONARY ARTERY STENOSIS	7
CIRCUMSTANCE OR INFORMATION CAPABLE OF LEADING TO MEDICATION ERROR	7
Choking	7
CAROTID ARTERY OCCLUSION	7
CARDIOPULMONARY FAILURE	7
CARDIAC VALVE DISEASE	7
BLOOD TRIGLYCERIDES INCREASED	7
Blood disorder	7
BACK INJURY	7
ATELECTASIS	7
Aphonia	7
ADVERSE EVENT	7
ACCIDENTAL OVERDOSE	7
ACCIDENT AT WORK	7
ABDOMINAL PAIN LOWER	7
Wrong product administered	6
WHITE BLOOD CELL COUNT DECREASED	6
Viral upper respiratory tract infection	6
VENOUS THROMBOSIS	6
TUNNEL VISION	6
TOXIC SKIN ERUPTION	6
Therapeutic response changed	6
Systemic scleroderma	6
Splenic infarction	6
Spinal cord disorder	6
SLEEP DISORDER	6
SKIN REACTION	6
SKIN EXFOLIATION	6
SKIN CANCER	6
SKIN BURNING SENSATION	6
SEXUAL ABUSE	6
SCIATICA	6
SARCOIDOSIS	6
RETINAL OEDEMA	6
RETINAL EXUDATES	6
RETINAL DEGENERATION	6
PULSE ABSENT	6
PSYCHOMOTOR HYPERACTIVITY	6
PROSTATOMEGALY	6
Post-traumatic stress disorder	6
PNEUMONIA BACTERIAL	6
PETECHIAE	6
Penile curvature	6
Pelvic fracture	6
PARKINSON'S DISEASE	6
Paresis	6
PANIC ATTACK	6
NOCTURIA	6
NO THERAPEUTIC RESPONSE	6
NIGHT BLINDNESS	6
NEPHROLITHIASIS	6
NEOPLASM	6
MUSCULOSKELETAL CHEST PAIN	6
MUSCLE TWITCHING	6
Micturition frequency decreased	6
METHAEMOGLOBINAEMIA	6
MENORRHAGIA	6
Macular detachment	6
Liver injury	6
JOINT EFFUSION	6
Joint dislocation	6
ISCHAEMIC HEPATITIS	6
INTENTIONAL MISUSE	6
INCONTINENCE	6
IIIRD NERVE PARALYSIS	6
HYPOPERFUSION	6
HYPERTONIC BLADDER	6
HIP ARTHROPLASTY	6
HICCUPS	6
HIATUS HERNIA	6
HEPATIC CONGESTION	6
HEPARIN-INDUCED THROMBOCYTOPENIA	6
HEAD DISCOMFORT	6
HAEMOLYSIS	6
GLUCOSE TOLERANCE IMPAIRED	6
GASTROENTERITIS VIRAL	6
FRACTURE	6
FAECES DISCOLOURED	6
EYELID OEDEMA	6
EYE IRRITATION	6
Extra dose administered	6
Executive dysfunction	6
EPILEPSY	6
ENDOTHELIAL DYSFUNCTION	6
EMOTIONAL DISORDER	6
ELECTROCARDIOGRAM QT PROLONGED	6
ECCHYMOSIS	6
EATING DISORDER	6
DRY EYE	6
DRUG WITHDRAWAL SYNDROME	6
DRUG TOLERANCE	6
DIASTOLIC DYSFUNCTION	6
DEVICE BREAKAGE	6
Creatinine renal clearance decreased	6
CONJUNCTIVAL HAEMORRHAGE	6
CONGESTIVE CARDIOMYOPATHY	6
COLITIS	6
CEREBRAL THROMBOSIS	6
Cerebral small vessel ischaemic disease	6
CEREBRAL ATROPHY	6
Catheter site infection	6
CAROTID ARTERY DISSECTION	6
CARDIAC OUTPUT DECREASED	6
BRAIN OEDEMA	6
BRAIN NEOPLASM	6
Blood uric acid increased	6
BLOOD TEST ABNORMAL	6
BLOOD PRESSURE SYSTOLIC INCREASED	6
BLOOD PRESSURE DIASTOLIC DECREASED	6
BLOOD GLUCOSE DECREASED	6
Blood count abnormal	6
ATRIAL SEPTAL DEFECT	6
ATAXIA	6
Accidental exposure to product	6
ACCIDENT	6
Walking distance test abnormal	5
VOLVULUS	5
VENOUS PRESSURE JUGULAR INCREASED	5
VASCULAR RESISTANCE PULMONARY INCREASED	5
VARICES OESOPHAGEAL	5
ULCER HAEMORRHAGE	5
Toxic shock syndrome	5
THYROID NEOPLASM	5
Thunderclap headache	5
THROAT TIGHTNESS	5
Throat cancer	5
Thirst	5
Therapy change	5
Therapeutic product effect decreased	5
TESTICULAR SWELLING	5
TACHYARRHYTHMIA	5
SWOLLEN TONGUE	5
SUDDEN VISUAL LOSS	5
STENT PLACEMENT	5
RIGHT VENTRICULAR HYPERTROPHY	5
Right ventricular dysfunction	5
RETINOPATHY HYPERTENSIVE	5
RETINAL VASCULITIS	5
RETINAL INFARCTION	5
RETINAL ARTERY THROMBOSIS	5
RESPIRATORY TRACT HAEMORRHAGE	5
Renal cancer	5
REFUSAL OF TREATMENT BY PATIENT	5
RALES	5
PULMONARY HYPERTENSIVE CRISIS	5
PULMONARY ARTERIAL PRESSURE DECREASED	5
Poor quality sleep	5
POLYURIA	5
PLATELET COUNT INCREASED	5
PERSISTENT FOETAL CIRCULATION	5
PERITONITIS BACTERIAL	5
PERIPHERAL VASCULAR DISORDER	5
PERIPHERAL ISCHAEMIA	5
PENILE VEIN THROMBOSIS	5
Oxygen saturation abnormal	5
Osteoporosis	5
OESOPHAGEAL DISORDER	5
NO ADVERSE EFFECT	5
NIGHT SWEATS	5
MOUTH ULCERATION	5
MOOD ALTERED	5
MICTURITION DISORDER	5
Metastatic neoplasm	5
MALNUTRITION	5
LACERATION	5
IRON DEFICIENCY ANAEMIA	5
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION	5
Impaired gastric emptying	5
Illness	5
HYPOTHERMIA	5
HYPERTHYROIDISM	5
HYPERCAPNIA	5
Heart transplant	5
GYNAECOMASTIA	5
Finger amputation	5
FEELING JITTERY	5
FACIAL PALSY	5
EYE PRURITUS	5
Exposure to toxic agent	5
EXOSTOSIS	5
EXCORIATION	5
EOSINOPHILIA	5
ENDOCARDITIS	5
ELECTROMECHANICAL DISSOCIATION	5
ELECTROCARDIOGRAM ST SEGMENT ELEVATION	5
ECHOCARDIOGRAM ABNORMAL	5
EAR INFECTION	5
DRUG LEVEL INCREASED	5
DRUG ERUPTION	5
DIFFICULTY IN WALKING	5
DIABETIC NEUROPATHY	5
DIABETES MELLITUS INADEQUATE CONTROL	5
DETACHMENT OF RETINAL PIGMENT EPITHELIUM	5
DERMATITIS EXFOLIATIVE	5
COORDINATION ABNORMAL	5
Chorioretinitis	5
CHOLECYSTITIS	5
CHLOROPSIA	5
Cerebral venous thrombosis	5
CAROTID ARTERY STENOSIS	5
CARDIAC FIBRILLATION	5
Cardiac dysfunction	5
BRONCHOPULMONARY ASPERGILLOSIS	5
BREAST CANCER	5
BLOOD URINE PRESENT	5
BLOOD PRESSURE INADEQUATELY CONTROLLED	5
Blood iron decreased	5
BLOOD CREATINE PHOSPHOKINASE MB INCREASED	5
BIPOLAR DISORDER	5
ATROPHY	5
ATRIAL TACHYCARDIA	5
ASPHYXIA	5
ARTERIOVENOUS MALFORMATION	5
Aortic dissection rupture	5
Anaphylactoid reaction	5
ANAPHYLACTIC REACTION	5
AFFECTIVE DISORDER	5
ACUTE SINUSITIS	5
Acute macular outer retinopathy	5
ACTIVITIES OF DAILY LIVING IMPAIRED	5
Accidental exposure to product by child	5
Vocal cord paralysis	4
VITREOUS DISORDER	4
VAGINAL HAEMORRHAGE	4
URINE OUTPUT DECREASED	4
TOXIC EPIDERMAL NECROLYSIS	4
THYROID DISORDER	4
Tension headache	4
Systolic hypertension	4
STRABISMUS	4
STEVENS-JOHNSON SYNDROME	4
SPLENOMEGALY	4
Sinus headache	4
SENSORY LOSS	4
SENSORY DISTURBANCE	4
Sensation of blood flow	4
SEBORRHOEIC KERATOSIS	4
Scoliosis	4
Right ventricular systolic pressure increased	4
Reversible cerebral vasoconstriction syndrome	4
RETINAL INJURY	4
RETINAL DEPOSITS	4
Respiratory tract congestion	4
RESPIRATORY RATE INCREASED	4
PUPILLARY DISORDER	4
Pulmonary vascular resistance abnormality	4
PULMONARY MASS	4
PSYCHOTIC DISORDER	4
Psoriasis	4
PROTHROMBIN TIME PROLONGED	4
PROSTATE EXAMINATION ABNORMAL	4
Product preparation error	4
Product label issue	4
Procedural haemorrhage	4
Primary headache associated with sexual activity	4
Prerenal failure	4
PREMATURE EJACULATION	4
POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME	4
POOR QUALITY DRUG ADMINISTERED	4
POOR PERIPHERAL CIRCULATION	4
Pharyngeal disorder	4
PENILE HAEMATOMA	4
PARAPLEGIA	4
Paranasal sinus discomfort	4
PANIC REACTION	4
Pancreatic carcinoma	4
OSTEONECROSIS	4
Osteomyelitis	4
Organ failure	4
ORAL PAIN	4
OPEN ANGLE GLAUCOMA	4
OCULAR HYPERTENSION	4
Ocular discomfort	4
NORMOCHROMIC NORMOCYTIC ANAEMIA	4
MYOPIA	4
MYDRIASIS	4
MULTIPLE SCLEROSIS	4
MULTIPLE INJURIES	4
Multi-organ disorder	4
MOVEMENT DISORDER	4
MITRAL VALVE DISEASE	4
METAMORPHOPSIA	4
LYMPHOMA	4
LOWER GASTROINTESTINAL HAEMORRHAGE	4
LOCALISED OEDEMA	4
LOCAL SWELLING	4
LIPASE INCREASED	4
Leukoencephalopathy	4
LEFT VENTRICULAR HYPERTROPHY	4
LARGE INTESTINAL HAEMORRHAGE	4
LACUNAR INFARCTION	4
IVth nerve paralysis	4
ISCHAEMIC CARDIOMYOPATHY	4
INTRA-ABDOMINAL HAEMORRHAGE	4
INTERVERTEBRAL DISC DISORDER	4
INGUINAL HERNIA	4
INCREASED BRONCHIAL SECRETION	4
INCORRECT ROUTE OF DRUG ADMINISTRATION	4
IMPAIRED HEALING	4
Immobile	4
IDIOPATHIC THROMBOCYTOPENIC PURPURA	4
Hypoglossal nerve paralysis	4
HYPERTRIGLYCERIDAEMIA	4
HYPERMETROPIA	4
HEPATOMEGALY	4
HEPATITIS	4
HEPATIC STEATOSIS	4
Hangover	4
HAND FRACTURE	4
HALO VISION	4
HALLUCINATION, VISUAL	4
HAEMORRHAGE SUBCUTANEOUS	4
HAEMODIALYSIS	4
Gravitational oedema	4
GRAND MAL CONVULSION	4
GOUTY ARTHRITIS	4
GOITRE	4
GASTROINTESTINAL INFLAMMATION	4
GASTRITIS EROSIVE	4
GASTRIC CANCER	4
Frustration tolerance decreased	4
FOETAL GROWTH RESTRICTION	4
FOAMING AT MOUTH	4
FIBROSIS	4
EYE INJURY	4
EXTREMITY NECROSIS	4
EJACULATION DELAYED	4
ECZEMA	4
DUODENAL ULCER	4
Drug reaction with eosinophilia and systemic symptoms	4
DRUG EFFECT PROLONGED	4
DRUG EFFECT INCREASED	4
DRUG ABUSER	4
DIVERTICULUM	4
DILATATION ATRIAL	4
DEVICE MALFUNCTION	4
Dermatitis bullous	4
Crohn's disease	4
Conjunctival hyperaemia	4
COLITIS ULCERATIVE	4
COLITIS ISCHAEMIC	4
CLOSTRIDIUM DIFFICILE COLITIS	4
Chest injury	4
Cheilitis	4
Cerebral amyloid angiopathy	4
CATHETER RELATED INFECTION	4
CAROTID ARTERY DISEASE	4
Cardiovascular insufficiency	4
CARDIAC STRESS TEST ABNORMAL	4
CANDIDIASIS	4
BRONCHOPNEUMONIA	4
BREAST CANCER FEMALE	4
BLOOD TESTOSTERONE ABNORMAL	4
BLOOD PRESSURE SYSTOLIC DECREASED	4
BLOOD ALBUMIN DECREASED	4
BLADDER SPASM	4
Basilar artery thrombosis	4
BACTERIAL INFECTION	4
BACTERAEMIA	4
ATRIOVENTRICULAR BLOCK FIRST DEGREE	4
ATRIOVENTRICULAR BLOCK COMPLETE	4
AORTIC ARTERIOSCLEROSIS	4
Anticoagulation drug level below therapeutic	4
Anti factor VIII antibody test	4
ANGIONEUROTIC OEDEMA	4
Anal ulcer	4
AMMONIA INCREASED	4
AMAUROSIS FUGAX	4
ACUTE HEPATIC FAILURE	4
Acquired haemophilia	4
ACCIDENTAL EXPOSURE	4
XANTHOPSIA	3
WRONG DRUG ADMINISTERED	3
Wrong dose	3
Wrist fracture	3
VENTRICULAR SEPTAL DEFECT	3
Ventricular remodelling	3
VEIN DISORDER	3
VASODILATION PROCEDURE	3
VASCULAR RUPTURE	3
VASCULAR OCCLUSION	3
Uterine cancer	3
URINE ANALYSIS ABNORMAL	3
URINARY TRACT DISORDER	3
URETHRAL HAEMORRHAGE	3
Upper-airway cough syndrome	3
UPPER RESPIRATORY TRACT INFLAMMATION	3
TRISMUS	3
Transfusion	3
Transcription medication error	3
TONGUE OEDEMA	3
TONGUE DISORDER	3
THROMBOTIC THROMBOCYTOPENIC PURPURA	3
Thrombosis corpora cavernosa	3
Therapy interrupted	3
Therapeutic product effect delayed	3
THERAPEUTIC AGENT TOXICITY	3
TENDONITIS	3
TEMPORAL ARTERITIS	3
SYNCOPE VASOVAGAL	3
SUFFOCATION FEELING	3
Substance use	3
STRIDOR	3
Still's disease	3
STAPHYLOCOCCAL BACTERAEMIA	3
SPUTUM DISCOLOURED	3
Soft tissue disorder	3
SNORING	3
SMALL INTESTINAL OBSTRUCTION	3
Sinus node dysfunction	3
SEXUAL DYSFUNCTION	3
SENSATION OF PRESSURE	3
ROSACEA	3
Rhinitis allergic	3
RETROGRADE EJACULATION	3
RETINITIS	3
RETINAL PIGMENT EPITHELIOPATHY	3
Retinal neovascularisation	3
RETINAL ARTERY EMBOLISM	3
RESUSCITATION	3
Respiration abnormal	3
RENAL CYST	3
REFLUX OESOPHAGITIS	3
RECTAL PROLAPSE	3
RASH PRURITIC	3
RASH GENERALISED	3
PURPURA	3
PUPILS UNEQUAL	3
Pulmonary vascular disorder	3
PROTEINURIA	3
PROSTATIC OPERATION	3
Product size issue	3
Product label confusion	3
Product administration error	3
Product administered to patient of inappropriate age	3
Procedural pain	3
PROCEDURAL COMPLICATION	3
PREMATURE LABOUR	3
PORTAL VEIN THROMBOSIS	3
POLYP	3
POLYNEUROPATHY	3
Pneumonia viral	3
Pleuritic pain	3
PHOTOSENSITIVITY REACTION	3
PHARYNGEAL OEDEMA	3
PHARMACEUTICAL PRODUCT COUNTERFEIT	3
PERITONEAL HAEMORRHAGE	3
PERIPHERAL COLDNESS	3
PEPTIC ULCER	3
PALATAL OEDEMA	3
Ototoxicity	3
ORAL DISORDER	3
OPTIC NERVE INJURY	3
Oligohydramnios	3
Obstructive airways disorder	3
NYSTAGMUS	3
NUCLEAR MAGNETIC RESONANCE IMAGING BRAIN ABNORMAL	3
Non-cardiogenic pulmonary oedema	3
Neutrophil count increased	3
NEUROGENIC BLADDER	3
Neoplasm recurrence	3
NEONATAL HYPOTENSION	3
N-terminal prohormone brain natriuretic peptide increased	3
MYOPATHY	3
Muscle injury	3
MUSCLE DISORDER	3
MULTIPLE FRACTURES	3
MOUTH HAEMORRHAGE	3
MIDDLE INSOMNIA	3
MEDICAL DEVICE COMPLICATION	3
MEAN ARTERIAL PRESSURE DECREASED	3
MASS	3
MACULAR HOLE	3
Lymphocyte count abnormal	3
LUNG NEOPLASM	3
Lumbar vertebral fracture	3
LOSS OF LIBIDO	3
Ligament sprain	3
Leukocytosis	3
LEG AMPUTATION	3
IRRITABILITY	3
IRON DEFICIENCY	3
Intracranial artery dissection	3
INTERMITTENT CLAUDICATION	3
Intentional dose omission	3
INGROWING NAIL	3
Infusion site erythema	3
Inappropriate schedule of product administration	3
IMPAIRED WORK ABILITY	3
ILL-DEFINED DISORDER	3
HYPOXIC ENCEPHALOPATHY	3
HYPOVENTILATION	3
HYPOTHYROIDISM	3
HYPOCALCAEMIA	3
HYPOAESTHESIA FACIAL	3
HYPERTENSIVE HEART DISEASE	3
HYPERSOMNIA	3
HYDROCEPHALUS	3
HYDROCELE	3
HEPATORENAL SYNDROME	3
HEPATITIS CHOLESTATIC	3
HEPATITIS C	3
HEPATITIS ACUTE	3
HEMIANOPIA HOMONYMOUS	3
HEART VALVE REPLACEMENT	3
HEART VALVE INCOMPETENCE	3
HAEMOTHORAX	3
Haemorrhoidal haemorrhage	3
HAEMORRHAGIC DIATHESIS	3
Haemorrhagic anaemia	3
Haemorrhage urinary tract	3
HAEMOLYTIC ANAEMIA	3
HAEMOGLOBIN INCREASED	3
Haemoglobin abnormal	3
Haematotoxicity	3
HAEMATOSPERMIA	3
HAEMATOCRIT INCREASED	3
HAEMANGIOMA	3
Glomerulonephritis minimal lesion	3
GLOMERULAR FILTRATION RATE ABNORMAL	3
GLARE	3
Gingival disorder	3
GENERAL PHYSICAL CONDITION ABNORMAL	3
Gastrointestinal infection	3
Gastritis hypertrophic	3
GANGRENE	3
Food poisoning	3
Fixed eruption	3
FAECALOMA	3
FAECAL INCONTINENCE	3
Face injury	3
EYE MOVEMENT DISORDER	3
Eye inflammation	3
EYE DISCHARGE	3
Exposure via partner	3
ERYTHEMA OF EYELID	3
ERYSIPELAS	3
ERUCTATION	3
EPSTEIN-BARR VIRUS INFECTION	3
Energy increased	3
Encephalomalacia	3
ELECTROLYTE IMBALANCE	3
EAR DISORDER	3
DYSTONIA	3
DYSPAREUNIA	3
Dyslexia	3
DYSKINESIA	3
DRUG SCREEN POSITIVE	3
DISTURBANCE IN SEXUAL AROUSAL	3
Disease complication	3
DIPLEGIA	3
Desmoplastic melanoma	3
Death neonatal	3
CYST	3
Cyanosis central	3
CORNEAL DISORDER	3
COR PULMONALE CHRONIC	3
Concomitant disease progression	3
COMPUTERISED TOMOGRAM ABNORMAL	3
Complication associated with device	3
COLONIC POLYP	3
COLON ADENOMA	3
Clostridium difficile infection	3
CHRONIC HEPATIC FAILURE	3
CHROMATURIA	3
CHOROIDAL NEOVASCULARISATION	3
CHOROIDAL INFARCTION	3
CHEST X-RAY ABNORMAL	3
CHEMOTHERAPY	3
Cerebellar infarction	3
CATHETER RELATED COMPLICATION	3
CAROTID ARTERY ATHEROMA	3
CAROTID ARTERIOSCLEROSIS	3
Cardiac sarcoidosis	3
CARDIAC PACEMAKER INSERTION	3
CARDIAC FLUTTER	3
Cardiac discomfort	3
CARBON DIOXIDE INCREASED	3
Caesarean section	3
BUNDLE BRANCH BLOCK LEFT	3
Bronchopulmonary dysplasia	3
BRONCHIECTASIS	3
BREATH SOUNDS ABNORMAL	3
BREAST PAIN	3
Bradypnoea	3
Body temperature increased	3
BODY TEMPERATURE DECREASED	3
BLOOD THYROID STIMULATING HORMONE INCREASED	3
BLOOD PRESSURE FLUCTUATION	3
BLOOD POTASSIUM INCREASED	3
BLOOD CREATINE INCREASED	3
BLOOD CALCIUM DECREASED	3
Blister	3
BILIRUBIN CONJUGATED INCREASED	3
BILE DUCT OBSTRUCTION	3
BENIGN INTRACRANIAL HYPERTENSION	3
Basal ganglia haemorrhage	3
AUTOIMMUNE HEPATITIS	3
ATTENTION DEFICIT/HYPERACTIVITY DISORDER	3
ASTHENOPIA	3
ARTHROPOD BITE	3
ARTHRITIS INFECTIVE	3
ARTERIAL STENOSIS	3
ARRHYTHMIA SUPRAVENTRICULAR	3
APPENDICITIS	3
APALLIC SYNDROME	3
ANOREXIA	3
AMENORRHOEA	3
ALCOHOL POISONING	3
Adulterated product	3
Acral lentiginous melanoma	3
ACIDOSIS	3
Weaning failure	2
WALKING DISABILITY	2
VITH NERVE PARALYSIS	2
VITAMIN D DEFICIENCY	2
Vertebral artery dissection	2
VENTRICULAR FAILURE	2
VENTRICULAR DYSKINESIA	2
VENTRICULAR DYSFUNCTION	2
Ventricular assist device insertion	2
Vein rupture	2
VASCULAR OPERATION	2
VASCULAR GRAFT	2
VASCULAR CALCIFICATION	2
UVEITIS	2
URINE FLOW DECREASED	2
URINARY TRACT OBSTRUCTION	2
URGE INCONTINENCE	2
UNRESPONSIVE TO PAIN STIMULI	2
Underweight	2
UNDERDOSE	2
TYMPANIC MEMBRANE PERFORATION	2
Troponin T increased	2
TROPONIN INCREASED	2
TRIGEMINAL NERVE DISORDER	2
Transverse sinus thrombosis	2
Transplant	2
Tracheal haemorrhage	2
TORSADE DE POINTES	2
Toothache	2
TOOTH LOSS	2
TOOTH INFECTION	2
Tooth fracture	2
TOOTH ABSCESS	2
Tibia fracture	2
THROMBOTIC STROKE	2
Thrombosis in device	2
THORACIC VERTEBRAL FRACTURE	2
THERMAL BURN	2
THERAPEUTIC RESPONSE INCREASED	2
THERAPEUTIC RESPONSE DELAYED	2
THALAMUS HAEMORRHAGE	2
TETANY	2
TESTICULAR DISORDER	2
TENSION	2
TENDON DISORDER	2
TENDERNESS	2
TACHYPHYLAXIS	2
SYSTEMIC SCLEROSIS	2
Symptom recurrence	2
Swelling of eyelid	2
SURGICAL PROCEDURE REPEATED	2
SUPRAVENTRICULAR EXTRASYSTOLES	2
SUPERINFECTION	2
Subretinal fluid	2
SUBDURAL HAEMORRHAGE	2
Stress cardiomyopathy	2
Stomatitis necrotising	2
STOMATITIS	2
Sternal fracture	2
STAPHYLOCOCCUS TEST POSITIVE	2
STAPHYLOCOCCAL SEPSIS	2
SPUTUM INCREASED	2
SPUTUM ABNORMAL	2
Spontaneous intrahepatic portosystemic venous shunt	2
SPLINTER HAEMORRHAGES	2
SPINAL DISORDER	2
Spinal cord ischaemia	2
SPINAL CORD INJURY	2
SPINAL COLUMN STENOSIS	2
SMALL INTESTINAL HAEMORRHAGE	2
SLUGGISHNESS	2
Sleep disorder due to general medical condition, insomnia type	2
SKIN HYPERPIGMENTATION	2
SKIN HAEMORRHAGE	2
Skin fissures	2
Skin abrasion	2
SINUS BRADYCARDIA	2
Shoulder fracture	2
SENSATION OF HEAVINESS	2
SEMEN VOLUME INCREASED	2
SEDATION	2
Secretion discharge	2
Seasonal allergy	2
SCROTAL PAIN	2
SCREAMING	2
Scratch	2
RHONCHI	2
RHINITIS	2
RETROPERITONEAL HAEMORRHAGE	2
Retinogram abnormal	2
Retinal vascular thrombosis	2
RETINAL SCAR	2
RESTRICTIVE PULMONARY DISEASE	2
RESPIRATORY TRACT INFECTION VIRAL	2
RESPIRATORY FUME INHALATION DISORDER	2
RENAL CELL CARCINOMA STAGE UNSPECIFIED	2
Renal artery dissection	2
RED BLOOD CELL SEDIMENTATION RATE INCREASED	2
Rectal cancer	2
Rebound effect	2
Rash papular	2
RADICAL PROSTATECTOMY	2
QUADRIPLEGIA	2
QUADRIPARESIS	2
PUPIL FIXED	2
PULMONARY VEIN STENOSIS	2
PULMONARY VALVE INCOMPETENCE	2
Pulmonary hypoplasia	2
Pulmonary capillary haemangiomatosis	2
PULMONARY ARTERY ANEURYSM	2
Pulmonary arteriovenous fistula	2
Pulmonary arterial wedge pressure increased	2
Psychotic symptom	2
PSEUDOMONAS INFECTION	2
PROTHROMBIN TIME ABNORMAL	2
PROSTATITIS	2
PROSTATECTOMY	2
PROSTATE CANCER RECURRENT	2
Product storage error	2
Product packaging issue	2
Product packaging confusion	2
Product colour issue	2
Prescribed underdose	2
PREGNANCY	2
POTENTIATING DRUG INTERACTION	2
POST PROCEDURAL INFECTION	2
Portal hypertension	2
Poor feeding infant	2
Polyhydramnios	2
POLYCHROMASIA	2
Poisoning	2
PO2 DECREASED	2
PNEUMONITIS	2
PNEUMONIA PNEUMOCOCCAL	2
Pneumonia fungal	2
PNEUMATOSIS INTESTINALIS	2
PLEURAL DISORDER	2
PLATELET FUNCTION TEST ABNORMAL	2
PLATELET DISORDER	2
Plasma cell myeloma	2
PINGUECULA	2
PHLEBITIS	2
PHIMOSIS	2
PHARYNGOLARYNGEAL PAIN	2
Pharyngeal abscess	2
Pericarditis	2
Pericardial drainage	2
PENILE SIZE REDUCED	2
Penile burning sensation	2
PARANOIA	2
Paranasal sinus hypersecretion	2
Paraesthesia oral	2
PAPILLITIS	2
Pancreatic disorder	2
Oxygen therapy	2
OTITIS MEDIA	2
Orgasm abnormal	2
ORGANIC ERECTILE DYSFUNCTION	2
ORAL CANDIDIASIS	2
OPTIC NERVE SHEATH HAEMORRHAGE	2
Optic nerve infarction	2
OPTIC NERVE HYPOPLASIA	2
OPTIC NERVE CUP/DISC RATIO DECREASED	2
OPTIC DISC VASCULAR DISORDER	2
Ophthalmic herpes zoster	2
ONYCHOMYCOSIS	2
OESOPHAGITIS	2
OESOPHAGEAL ULCER	2
OESOPHAGEAL STENOSIS	2
OEDEMA GENITAL	2
OEDEMA DUE TO CARDIAC DISEASE	2
ODYNOPHAGIA	2
OCULAR ICTERUS	2
NUCLEAR MAGNETIC RESONANCE IMAGING ABNORMAL	2
NO ADVERSE REACTION	2
NO ADVERSE DRUG EFFECT	2
NEUTROPENIA	2
NEUROPATHY	2
NEPHROTIC SYNDROME	2
NEPHROSCLEROSIS	2
NEPHROGENIC ANAEMIA	2
NECROTISING COLITIS	2
Neck mass	2
Neck injury	2
Nasal septum deviation	2
NASAL OEDEMA	2
NASAL MUCOSAL DISORDER	2
NARCOLEPSY	2
MYOGLOBIN BLOOD INCREASED	2
Myoclonus	2
Myocardial rupture	2
MYELODYSPLASTIC SYNDROME	2
MUSCLE TIGHTNESS	2
MUSCLE SPASTICITY	2
MUSCLE RUPTURE	2
MUSCLE FATIGUE	2
MUSCLE ATROPHY	2
MULTIPLE MYELOMA	2
MUCOSAL HAEMORRHAGE	2
Mouth swelling	2
MONOCYTE COUNT INCREASED	2
MITRAL VALVE STENOSIS	2
MIGRAINE WITH AURA	2
Middle ear effusion	2
Micrococcus test positive	2
MICROANGIOPATHIC HAEMOLYTIC ANAEMIA	2
METRORRHAGIA	2
Metastatic carcinoid tumour	2
Metastases to spleen	2
Metastases to pancreas	2
Metastases to neck	2
METABOLIC ENCEPHALOPATHY	2
METABOLIC DISORDER	2
Mesenteric haematoma	2
MENINGITIS	2
MENIERE'S DISEASE	2
Marasmus	2
Mallory-Weiss syndrome	2
Lymphoedema	2
Lung carcinoma cell type unspecified stage IV	2
LOW CARDIAC OUTPUT SYNDROME	2
Loss of visual contrast sensitivity	2
LOCALISED INTRAABDOMINAL FLUID COLLECTION	2
LIVER TRANSPLANT	2
LIPIDS INCREASED	2
LIP OEDEMA	2
LIP DISORDER	2
Limb operation	2
LIBIDO INCREASED	2
Libido disorder	2
LEUKOCYTOCLASTIC VASCULITIS	2
LENTICULAR OPACITIES	2
LARYNGEAL CANCER	2
LACRIMATION DECREASED	2
Jugular vein distension	2
JUDGEMENT IMPAIRED	2
Joint stiffness	2
ISCHAEMIC CEREBRAL INFARCTION	2
Iridocyclitis	2
INTRAOCULAR PRESSURE TEST ABNORMAL	2
Intracranial venous sinus thrombosis	2
Intracranial mass	2
Intracranial aneurysm	2
INTESTINAL INFARCTION	2
INTERVERTEBRAL DISC COMPRESSION	2
INJECTION SITE SWELLING	2
Injection site reaction	2
Injection site pain	2
Infusion site pain	2
Infusion site haemorrhage	2
Influenza B virus test positive	2
INFERTILITY	2
Infantile vomiting	2
Increased ventricular preload	2
INCREASED UPPER AIRWAY SECRETION	2
INCORRECT STORAGE OF DRUG	2
Incoherent	2
Inappropriate affect	2
Immunosuppression	2
IMMUNE SYSTEM DISORDER	2
ILEUS PARALYTIC	2
HYPOXIC-ISCHAEMIC ENCEPHALOPATHY	2
Hypopnoea	2
HYPOMANIA	2
Hypocoagulable state	2
HYPOCHROMIC ANAEMIA	2
HYPOAESTHESIA ORAL	2
Hyperventilation	2
HYPERURICAEMIA	2
HYPERTENSIVE CARDIOMEGALY	2
Hypersensitivity vasculitis	2
HYPERKERATOSIS	2
HYPERCOAGULATION	2
Hyperchlorhydria	2
HYPERCALCAEMIA	2
HYPERAMMONAEMIA	2
HYDRONEPHROSIS	2
HIV INFECTION	2
HISTOPLASMOSIS	2
HISTIOCYTOSIS HAEMATOPHAGIC	2
HILAR LYMPHADENOPATHY	2
HERNIA REPAIR	2
Hepatopulmonary syndrome	2
Hepatocellular carcinoma	2
Hepatitis B	2
HEPATITIS A	2
HEPATIC NEOPLASM MALIGNANT	2
HEPATIC ENCEPHALOPATHY	2
Hepatic cancer	2
HEMIANOPIA	2
Heart rate abnormal	2
HAIR GROWTH ABNORMAL	2
HAEMODYNAMIC TEST ABNORMAL	2
GUN SHOT WOUND	2
GROIN PAIN	2
GRANULOMA	2
GLAUCOMATOUS OPTIC DISC ATROPHY	2
Gingival bleeding	2
GENITAL SWELLING	2
GASTROINTESTINAL ULCER	2
Gastrointestinal melanoma	2
GASTROINTESTINAL HYPOMOTILITY	2
GASTRITIS HAEMORRHAGIC	2
Gastric ulcer	2
GASTRIC INFECTION	2
Galectin-3 increased	2
Gait inability	2
FUNDOSCOPY ABNORMAL	2
FULL BLOOD COUNT DECREASED	2
FREQUENT BOWEL MOVEMENTS	2
Foveal degeneration	2
FOREIGN BODY	2
FOOT OPERATION	2
Focal dyscognitive seizures	2
FIBROMYALGIA	2
Feeling of relaxation	2
Feeding disorder	2
Fat tissue increased	2
FACIAL PARESIS	2
Facial paralysis	2
EYELID FUNCTION DISORDER	2
Eye infection	2
EXTRASYSTOLES	2
EXTRAOCULAR MUSCLE DISORDER	2
Exposure via breast milk	2
EXOPHTHALMOS	2
EXERCISE TEST ABNORMAL	2
Excessive dynamic airway collapse	2
Euphoric mood	2
Erythrosis	2
EPIGASTRIC DISCOMFORT	2
EPIDIDYMAL CYST	2
Eosinophil count increased	2
Endotracheal intubation	2
ENCEPHALITIS	2
EMBOLISM	2
ELECTROCARDIOGRAM QRS COMPLEX PROLONGED	2
Echocardiogram	2
Ear haemorrhage	2
DYSPNOEA PAROXYSMAL NOCTURNAL	2
DYSPNOEA EXACERBATED	2
DYSPHASIA	2
Dyslipidaemia	2
Dysgraphia	2
DYSAESTHESIA	2
DRY THROAT	2
DROOLING	2
DIVERTICULUM INTESTINAL	2
DIARRHOEA INFECTIOUS	2
Diaphragmatic hernia	2
DIABETIC COMPLICATION	2
DIABETES MELLITUS NON-INSULIN-DEPENDENT	2
Device related sepsis	2
Device occlusion	2
Developmental delay	2
DERMATITIS CONTACT	2
DERMATITIS ALLERGIC	2
DERMATITIS	2
DEPENDENCE ON ENABLING MACHINE OR DEVICE	2
DELUSION	2
DEFAECATION URGENCY	2
Decreased interest	2
CYTOMEGALOVIRUS INFECTION	2
CYTOLYTIC HEPATITIS	2
CYSTIC FIBROSIS	2
CSF TEST ABNORMAL	2
CREST syndrome	2
Coronary artery dilatation	2
Coronary arterial stent insertion	2
Contraindicated drug administered	2
CONSCIOUSNESS FLUCTUATING	2
Congenital pulmonary artery anomaly	2
COMPRESSION FRACTURE	2
COAGULATION TIME PROLONGED	2
CLUSTER HEADACHE	2
CLUMSINESS	2
CLOSTRIDIAL INFECTION	2
Clavicle fracture	2
CLAUSTROPHOBIA	2
CHRONIC RIGHT VENTRICULAR FAILURE	2
Choroid melanoma	2
CHORIORETINAL DISORDER	2
CHOREOATHETOSIS	2
CHOREA	2
CHOLECYSTECTOMY	2
CERVICOBRACHIAL SYNDROME	2
CEREBROVASCULAR DISORDER	2
Cerebral disorder	2
Cerebral calcification	2
CEREBRAL ARTERY THROMBOSIS	2
CEREBRAL ARTERY STENOSIS	2
CEREBRAL ARTERY OCCLUSION	2
Central venous catheterisation	2
CENTRAL LINE INFECTION	2
CATHETER SITE RELATED REACTION	2
Catheter management	2
CATARACT NUCLEAR	2
Carpal tunnel syndrome	2
CAROTID BRUIT	2
Cardiorenal syndrome	2
Cardiac myxoma	2
Cardiac index increased	2
CARDIAC INDEX DECREASED	2
CARDIAC HYPERTROPHY	2
CARDIAC FAILURE HIGH OUTPUT	2
Cardiac death	2
Carcinoid syndrome	2
CALCULUS URINARY	2
CALCINOSIS	2
Bursitis	2
BRAIN HERNIATION	2
Bradyphrenia	2
BRADYARRHYTHMIA	2
BONE MARROW DEPRESSION	2
BONE DENSITY DECREASED	2
BLOOD TESTOSTERONE INCREASED	2
BLOOD HOMOCYSTEINE INCREASED	2
BLOOD GLUCOSE ABNORMAL	2
Blood culture positive	2
BLOOD CHLORIDE DECREASED	2
BLOOD ALBUMIN ABNORMAL	2
BLEPHARITIS	2
BLADDER NEOPLASM	2
Bladder disorder	2
BLADDER CANCER	2
Biopsy liver	2
Bile duct stone	2
Bedridden	2
AZOTAEMIA	2
Axillary mass	2
AUTOIMMUNE DISORDER	2
Auditory disorder	2
ATRIOVENTRICULAR BLOCK SECOND DEGREE	2
Atrial septal defect repair	2
ASTIGMATISM	2
ARTERIOSPASM CORONARY	2
APNOEA	2
Anomalous pulmonary venous connection	2
ANGLE CLOSURE GLAUCOMA	2
ANGINA UNSTABLE	2
Anger	2
ANEURYSM RUPTURED	2
ANALGESIC THERAPY	2
ANAESTHETIC COMPLICATION	2
ANAEMIA OF CHRONIC DISEASE	2
AMYLOIDOSIS	2
AMPHETAMINES POSITIVE	2
Amblyopia	2
AMAUROSIS	2
Alcohol abuse	2
ADVERSE DRUG REACTION	2
Acute lymphocytic leukaemia recurrent	2
ABNORMAL DREAMS	2
ABDOMINAL HERNIA	2
Yellow skin	1
Wrong schedule	1
Wrong route	1
Wrong patient received product	1
Wound infection staphylococcal	1
Wound infection bacterial	1
WOUND HAEMORRHAGE	1
White matter lesion	1
WHEELCHAIR USER	1
WEIGHT BELOW NORMAL	1
Wallenberg syndrome	1
WALDENSTROM'S MACROGLOBULINAEMIA	1
VULVOVAGINITIS	1
Vulvovaginal pruritus	1
VOCAL CORD PARESIS	1
Vocal cord neoplasm	1
Vitamin D decreased	1
VITAMIN B12 INCREASED	1
Vitamin B12 deficiency	1
Vitamin B complex deficiency	1
Visual field tests abnormal	1
VISUAL ACUITY TESTS	1
VISUAL ACUITY REDUCED TRANSIENTLY	1
Viral test positive	1
VICTIM OF HOMICIDE	1
VICTIM OF CRIME	1
VESTIBULAR DISORDER	1
VERTIGO POSITIONAL	1
Vertebral foraminal stenosis	1
VERTEBRAL ARTERY STENOSIS	1
Ventricular septal defect repair	1
VENOUS STASIS	1
Venous pressure increased	1
Venous occlusion	1
Venous haemorrhage	1
VENA CAVA THROMBOSIS	1
Vena cava injury	1
Vasospasm	1
VASOMOTOR RHINITIS	1
VASOCONSTRICTION	1
VASCULITIS GASTROINTESTINAL	1
VASCULITIS	1
Vascular stent restenosis	1
VASCULAR SHUNT	1
VASCULAR RESISTANCE SYSTEMIC DECREASED	1
Vascular malformation	1
Vascular insufficiency	1
VASCULAR GRAFT OCCLUSION	1
VASCULAR ENCEPHALOPATHY	1
Vascular compression	1
VASCULAR BYPASS GRAFT	1
Vascular access complication	1
Varicose vein	1
VAGINAL LESION	1
Vaginal inflammation	1
VAGINAL DISCHARGE	1
Vaginal cyst	1
UVULITIS	1
UTERINE HAEMORRHAGE	1
Uterine disorder	1
URINE OUTPUT INCREASED	1
Urinary tract infection fungal	1
URINARY BLADDER HAEMORRHAGE	1
Ureteric stenosis	1
URETERIC CANCER	1
URETERAL NEOPLASM	1
Upper extremity mass	1
UNWANTED PREGNANCY	1
UNEXPECTED THERAPEUTIC DRUG EFFECT	1
UMBILICAL HERNIA, OBSTRUCTIVE	1
UMBILICAL HERNIA	1
ULNAR NERVE INJURY	1
Ulcerative keratitis	1
Type IV hypersensitivity reaction	1
Tumour rupture	1
Tumour marker increased	1
Tumour haemorrhage	1
Tuberculosis	1
Troponin abnormal	1
Trisomy 21	1
TRISOMY 18	1
Tricuspid valve disease	1
Traumatic lung injury	1
Traumatic intracranial haemorrhage	1
Traumatic intracranial haematoma	1
Traumatic haemorrhage	1
TRAUMATIC BRAIN INJURY	1
TRANSURETHRAL PROSTATECTOMY	1
TRANSPLANT REJECTION	1
Transplant failure	1
Transplant evaluation	1
TRACHEOSTOMY	1
Total lung capacity decreased	1
Tooth injury	1
TOOTH DISCOLOURATION	1
Tonsillectomy	1
TONSILLAR DISORDER	1
Tonsil cancer	1
TONIC CONVULSION	1
TONGUE DISCOLOURATION	1
Tongue coated	1
Toe amputation	1
TOBACCO ABUSE	1
Tinea versicolour	1
Tic	1
Thyroxine free abnormal	1
THYROIDITIS	1
THYROIDECTOMY	1
Thyroid hormones increased	1
Thymic cyst	1
THROMBOTIC MICROANGIOPATHY	1
Threatened labour	1
THINKING ABNORMAL	1
Thermohypoaesthesia	1
THERAPY REGIMEN CHANGED	1
Therapeutic product ineffective for unapproved indication	1
Therapeutic product effect variable	1
TESTIS CANCER	1
Testicular neoplasm	1
Testicular mass	1
Tendon rupture	1
Tendon injury	1
TEMPOROMANDIBULAR JOINT SYNDROME	1
Temperature regulation disorder	1
Tachyphrenia	1
TABLET PHYSICAL ISSUE	1
Systolic dysfunction	1
Systemic sclerosis pulmonary	1
SYSTEMIC INFLAMMATORY RESPONSE SYNDROME	1
SUTURE RUPTURE	1
SUPRAPUBIC PAIN	1
Superior sagittal sinus thrombosis	1
SUICIDAL BEHAVIOUR	1
Subendocardial ischaemia	1
Subcutaneous haematoma	1
STUPOR	1
STRESS URINARY INCONTINENCE	1
Stress ulcer	1
Stool analysis abnormal	1
STENT OCCLUSION	1
Stenotrophomonas infection	1
STEM CELL TRANSPLANT	1
STAPHYLOCOCCAL ABSCESS	1
SPUTUM CULTURE POSITIVE	1
Spondylitis	1
SPLENIC RUPTURE	1
Splenic lesion	1
SPLENECTOMY	1
Spleen disorder	1
Spleen congestion	1
Spirometry abnormal	1
Spinal pain	1
Spinal osteoarthritis	1
Spinal operation	1
Spinal deformity	1
Spinal cord compression	1
Spinal compression fracture	1
SPIDER NAEVUS	1
Spermatozoa abnormal	1
SOFT TISSUE INJURY	1
SOCIAL AVOIDANT BEHAVIOUR	1
SMOKER	1
Small intestine ulcer	1
SMALL CELL LUNG CANCER STAGE UNSPECIFIED	1
SLEEP TERROR	1
SLEEP STUDY ABNORMAL	1
Sleep study	1
Skull fractured base	1
Skull fracture	1
SKIN WARM	1
Skin tightness	1
Skin papilloma	1
Skin operation	1
Skin necrosis	1
Skin mass	1
SKIN LACERATION	1
Skin irritation	1
Skin injury	1
Skin infection	1
Skin cancer metastatic	1
SKIN BACTERIAL INFECTION	1
Skin atrophy	1
Skeletal injury	1
Sinus rhythm	1
Sinus arrhythmia	1
Sickle cell anaemia	1
Sick sinus syndrome	1
SHOULDER PAIN	1
SHOULDER OPERATION	1
SEXUALLY TRANSMITTED DISEASE	1
SEXUAL OFFENCE	1
SERRATIA INFECTION	1
Serous retinal detachment	1
Serositis	1
Septic arthritis staphylococcal	1
Sensitivity to weather change	1
Senile dementia	1
SELF MUTILATION	1
SELF ESTEEM DECREASED	1
Scrotal swelling	1
SCROTAL OEDEMA	1
SCROTAL HAEMATOMA	1
Scrotal cyst	1
Scleroderma renal crisis	1
Sclerema	1
SCLERAL PIGMENTATION	1
SCLERAL DISORDER	1
SCINTILLATING SCOTOMA	1
SCHIZOPHRENIA, PARANOID TYPE	1
SCHISTOSOMIASIS	1
SCHAMBERG'S DISEASE	1
Salivary hypersecretion	1
Salivary gland disorder	1
RUPTURED CEREBRAL ANEURYSM	1
ROTAVIRUS INFECTION	1
Rotator cuff repair	1
Right-to-left cardiac shunt	1
Right atrial dilatation	1
RHEUMATOID FACTOR POSITIVE	1
Retroperitoneal fibrosis	1
Retrograde amnesia	1
RETINAL PALLOR	1
Retinal melanoma	1
RETINAL DYSTROPHY	1
Retinal artery stenosis	1
RETINAL ANEURYSM	1
Restrictive cardiomyopathy	1
Respiratory syncytial virus infection	1
Respiratory syncytial virus bronchiolitis	1
Respiratory moniliasis	1
RESPIRATORY GAS EXCHANGE DISORDER	1
RESPIRATORY DEPRESSION	1
RENAL PAIN	1
RENAL NEOPLASM	1
Renal mass	1
Renal infarct	1
Renal hypertension	1
RENAL CELL CARCINOMA	1
Renal cancer stage IV	1
RENAL CANCER METASTATIC	1
Renal atrophy	1
RENAL ANEURYSM	1
REMOVAL OF TRANSPLANTED ORGAN	1
REGURGITATION	1
REFUSAL OF TREATMENT BY RELATIVE	1
RED BLOOD CELLS URINE POSITIVE	1
RED BLOOD CELLS URINE	1
RED BLOOD CELL MORPHOLOGY ABNORMAL	1
RED BLOOD CELL COUNT INCREASED	1
Rectal tenesmus	1
Reaction to drug excipients	1
RASH PUSTULAR	1
Rash maculo-papular	1
RASH MACULAR	1
RADIUS FRACTURE	1
RADIOTHERAPY	1
Radiculopathy	1
RADIATION INJURY	1
Quality of life decreased	1
QRS AXIS ABNORMAL	1
PYURIA	1
Pyloric stenosis	1
Pyelonephritis	1
PULSE PRESSURE DECREASED	1
PULPITIS DENTAL	1
Pulmonary sepsis	1
PULMONARY SARCOIDOSIS	1
PULMONARY INFARCTION	1
Pulmonary function test decreased	1
Pulmonary function test abnormal	1
PULMONARY ARTERY THERAPEUTIC PROCEDURE	1
PULMONARY ARTERY DILATATION	1
PULMONARY ARTERIAL PRESSURE ABNORMAL	1
PSYCHIATRIC SYMPTOM	1
Psoas abscess	1
PSEUDOMYXOMA PERITONEI	1
PRURITUS GENERALISED	1
PROTHROMBIN TIME SHORTENED	1
PROTHROMBIN LEVEL DECREASED	1
PROTEIN URINE PRESENT	1
PROSTHESIS IMPLANTATION	1
PROSTATISM	1
PROSTATIC SPECIFIC ANTIGEN DECREASED	1
Prostatic specific antigen abnormal	1
Prostatic pain	1
PROSTATIC OBSTRUCTION	1
Prostatic haemorrhage	1
PROSTATE CANCER STAGE I	1
Prostate cancer metastatic	1
Promotion of wound healing	1
Prolactin-producing pituitary tumour	1
Product use complaint	1
Product selection error	1
Product reconstitution quality issue	1
Product preparation issue	1
Product physical issue	1
Product name confusion	1
Product lot number issue	1
Product expiration date issue	1
Product dose omission in error	1
Product dispensing issue	1
Product communication issue	1
Product commingling	1
Product coating issue	1
Product availability issue	1
PROCTITIS	1
PROCTALGIA	1
Procedural hypotension	1
Primary hyperaldosteronism	1
PRESUMED OCULAR HISTOPLASMOSIS SYNDROME	1
Prescription form tampering	1
Precancerous cells present	1
Poverty of thought content	1
Postoperative wound infection	1
Postoperative respiratory failure	1
POSTOPERATIVE HERNIA	1
POSTOPERATIVE FEVER	1
POSTMENOPAUSAL HAEMORRHAGE	1
POST PROCEDURAL OEDEMA	1
Post procedural haematoma	1
Post procedural cellulitis	1
Post herpetic neuralgia	1
Portopulmonary hypertension	1
Portal vein pressure increased	1
Polymyositis	1
POLYMYALGIA RHEUMATICA	1
Polycythaemia	1
PO2 ABNORMAL	1
Pneumonia staphylococcal	1
Pneumonia legionella	1
Pneumonia klebsiella	1
Pneumocystis jirovecii pneumonia	1
Pneumocystis jirovecii infection	1
PLEURAL FIBROSIS	1
Pleural calcification	1
PLASMAPHERESIS	1
PITUITARY TUMOUR BENIGN	1
PITUITARY HAEMORRHAGE	1
PIGMENTATION DISORDER	1
PIGMENT DISPERSION SYNDROME	1
PHYSICAL PRODUCT LABEL ISSUE	1
Physical deconditioning	1
PHYSICAL ASSAULT	1
PHOSPHENES	1
Phonophobia	1
PHLEBITIS INFECTIVE	1
PHARYNGITIS	1
Pharyngeal injury	1
Petit mal epilepsy	1
PERTUSSIS	1
Personality disorder	1
PERSEVERATION	1
PERITONITIS	1
PERISTALSIS VISIBLE	1
Peripheral pulse decreased	1
Peripheral nerve injury	1
PERIPHERAL ARTERY ANEURYSM	1
Peripheral arterial occlusive disease	1
PERIPANCREATIC FLUID COLLECTION	1
PERIODONTITIS	1
PERICARDITIS ADHESIVE	1
Pericardial haemorrhage	1
Performance status decreased	1
PERFORMANCE FEAR	1
PERCUSSION TEST ABNORMAL	1
Penis injury	1
PENIS DEVIATION	1
PENILE WART	1
Penile vascular disorder	1
PENILE PROSTHESIS INSERTION	1
Penile discharge	1
PENILE ABSCESS	1
Pelvic prolapse	1
Pelvic pain	1
PELVI-URETERIC OBSTRUCTION	1
PCO2 INCREASED	1
PATENT DUCTUS ARTERIOSUS REPAIR	1
Patent ductus arteriosus	1
Patella fracture	1
PARATRACHEAL LYMPHADENOPATHY	1
PARANEOPLASTIC SYNDROME	1
Paranasal sinus injury	1
Papule	1
PANCREATITIS RELAPSING	1
PANCREATIC NEOPLASM	1
Pancreatic cyst	1
PANCREATIC CARCINOMA METASTATIC	1
Pancreatic abscess	1
PANCREAS LIPOMATOSIS	1
Pancreas infection	1
Palmar erythema	1
Painful respiration	1
Pain of skin	1
Oxygen supplementation	1
OXYGEN SATURATION INCREASED	1
OXYGEN SATURATION	1
Overweight	1
OVARIAN FAILURE	1
Otorrhoea	1
OTITIS EXTERNA	1
Osteoporotic fracture	1
Osteopenia	1
OSTEOMYELITIS ACUTE	1
OSCILLOPSIA	1
Oropharyngeal discomfort	1
Oropharyngeal cancer	1
Orchitis noninfective	1
Orchitis	1
ORCHIDECTOMY	1
ORBITAL CYST	1
ORAL SOFT TISSUE DISORDER	1
Oral mucosal exfoliation	1
ORAL INTAKE REDUCED	1
Oral herpes	1
Oral discomfort	1
Optical coherence tomography abnormal	1
OPTIC NEURITIS RETROBULBAR	1
OPTIC DISC DRUSEN	1
OPERATIVE HAEMORRHAGE	1
Onychomadesis	1
Off label use of device	1
Oesophagogastric fundoplasty	1
OESOPHAGEAL SPASM	1
OESOPHAGEAL OEDEMA	1
OESOPHAGEAL OBSTRUCTION	1
Oesophageal haemorrhage	1
Oesophageal carcinoma	1
OESOPHAGEAL CANDIDIASIS	1
OCCULT BLOOD POSITIVE	1
Obsessive-compulsive disorder	1
Obsessive thoughts	1
NORMAL TENSION GLAUCOMA	1
Normal newborn	1
NONSPECIFIC REACTION	1
Noninfective gingivitis	1
Nodule	1
NOCTIPHOBIA	1
NOCARDIOSIS	1
NO REACTION ON PREVIOUS EXPOSURE TO DRUG	1
Nipple pain	1
Nipple exudate bloody	1
Nipple disorder	1
NEUROPATHIC PAIN	1
Neuromyopathy	1
NEUROLOGICAL SYMPTOM	1
NEUROLOGICAL EXAMINATION ABNORMAL	1
Neurological decompensation	1
Neurologic neglect syndrome	1
Neurofibrosarcoma	1
Neuroendocrine carcinoma of the skin	1
Neurodevelopmental disorder	1
NEURODEGENERATIVE DISORDER	1
NERVE DEGENERATION	1
Nephropathy	1
NEPHRITIS INTERSTITIAL	1
Neonatal respiratory distress syndrome	1
Neonatal respiratory distress	1
Neonatal asphyxia	1
NECROSIS	1
Neck surgery	1
NASOPHARYNGEAL REFLUX	1
Nasal injury	1
Nasal inflammation	1
Nasal disorder	1
NASAL DISCOMFORT	1
Myotonic dystrophy	1
MYOCLONIC EPILEPSY	1
MYELOPATHY	1
Myelitis transverse	1
MYCOTOXICOSIS	1
MYCOSIS FUNGOIDES	1
Mycobacterium avium complex infection	1
Musculoskeletal injury	1
MUSCULAR DYSTROPHY	1
MUSCLE ENZYME INCREASED	1
Muscle contractions involuntary	1
Multiple sclerosis relapse	1
MULTIPLE DRUG OVERDOSE INTENTIONAL	1
MULTIPLE CHEMICAL SENSITIVITY	1
Mucosal inflammation	1
Mucosal hyperaemia	1
MOTION SICKNESS	1
MORPHOEA	1
Mood swings	1
Monoparesis	1
MONOCYTE PERCENTAGE INCREASED	1
Monoclonal gammopathy	1
MIXED LIVER INJURY	1
Mixed connective tissue disease	1
Mitral valve replacement	1
MITRAL VALVE CALCIFICATION	1
MIDDLE EAR DISORDER	1
MICROCYTOSIS	1
Microcytic anaemia	1
MICROANGIOPATHY	1
METASTATIC SQUAMOUS CELL CARCINOMA	1
Metastases to spinal cord	1
Metastases to small intestine	1
Metastases to retroperitoneum	1
Metastases to peritoneum	1
Metastases to eye	1
Metastases to adrenals	1
METAPLASIA	1
Metabolic surgery	1
MESENTERIC OCCLUSION	1
Mental fatigue	1
Mental disorder due to a general medical condition	1
MENSTRUAL DISORDER	1
MENISCUS LESION	1
Meniscus injury	1
Meningoencephalitis viral	1
Melanoderma	1
Melanocytic hyperplasia	1
Melanaemia	1
MEDICATION TAMPERING	1
MEDICATION CRYSTALS IN URINE	1
Medical device site pain	1
Medical device site infection	1
Medical device removal	1
Mediastinal abscess	1
Mechanical ventilation	1
Mechanical ileus	1
MEAN PLATELET VOLUME INCREASED	1
Mastocytosis	1
Mantle cell lymphoma	1
MALIGNANT SPLENIC NEOPLASM	1
Malignant pleural effusion	1
Malignant neoplasm progression	1
Malignant anorectal neoplasm	1
Malabsorption from injection site	1
Malabsorption	1
MACULAR SCAR	1
Macular reflex abnormal	1
MACULAR ISCHAEMIA	1
Macular fibrosis	1
MACROCYTOSIS	1
Lymphocytic leukaemia	1
LYMPHOCYTE PERCENTAGE DECREASED	1
LYMPHOCYTE COUNT INCREASED	1
Lymphocyte count decreased	1
Lymphocele	1
Lymphangioleiomyomatosis	1
Lymphadenopathy mediastinal	1
Lupus nephritis	1
Lung opacity	1
Lung infiltration	1
LUNG CONSOLIDATION	1
LUNG CANCER METASTATIC	1
Lower respiratory tract congestion	1
LOWER LIMB DEFORMITY	1
Low birth weight baby	1
LOSS OF CONTROL OF LEGS	1
LOCALISED OSTEOARTHRITIS	1
LOBAR PNEUMONIA	1
Liver function test increased	1
LIVE BIRTH	1
Lipoma	1
LIP ULCERATION	1
Lip pain	1
Lip and/or oral cavity cancer	1
Ligament rupture	1
Leukoplakia	1
LEUKOCYTE ANTIGEN B-27 POSITIVE	1
LEUKOARAIOSIS	1
LEUKAEMIA	1
LENS DISORDER	1
LENS DISLOCATION	1
LEIOMYOSARCOMA	1
LEFT VENTRICULAR HEAVE	1
Left ventricular dilatation	1
LEFT VENTRICLE OUTFLOW TRACT OBSTRUCTION	1
Left atrial enlargement	1
Laryngospasm	1
LARYNGEAL ERYTHEMA	1
Large intestine polyp	1
LARGE INTESTINE PERFORATION	1
Large intestine infection	1
LARGE INTESTINAL ULCER	1
Language disorder	1
Langerhans' cell histiocytosis	1
Lacrimal disorder	1
LABYRINTHITIS	1
LABILE HYPERTENSION	1
LABILE BLOOD PRESSURE	1
Labelled drug-drug interaction medication error	1
KNEE OPERATION	1
KNEE ARTHROPLASTY	1
KLEBSIELLA INFECTION	1
Kidney transplant rejection	1
Kidney infection	1
Kidney enlargement	1
KERATORHEXIS	1
KERATOCONJUNCTIVITIS SICCA	1
KELOID SCAR	1
Joint lock	1
JOINT LIGAMENT RUPTURE	1
Jaw fracture	1
Jaw disorder	1
JAUNDICE CHOLESTATIC	1
Irritable bowel syndrome	1
Irregular breathing	1
IRITIS	1
IRIS TRANSILLUMINATION DEFECT	1
Iris melanoma	1
Intraventricular haemorrhage	1
INTRACARDIAC THROMBUS	1
Intracardiac pressure increased	1
Intra-abdominal fluid collection	1
Intestinal varices haemorrhage	1
INTESTINAL POLYP	1
Intestinal perforation	1
INTESTINAL OPERATION	1
Intestinal mass	1
Intestinal haemorrhage	1
Intestinal haematoma	1
Intestinal dilatation	1
Intestinal cyst	1
INTESTINAL CONGESTION	1
INTESTINAL ADHESION LYSIS	1
INTERTRIGO CANDIDA	1
Intertrigo	1
Interruption of aortic arch	1
INTERNATIONAL NORMALISED RATIO FLUCTUATION	1
Intercostal neuralgia	1
Intercepted product prescribing error	1
Intercepted product dispensing error	1
Intercepted medication error	1
Intentional self-injury	1
Intensive care	1
Insurance issue	1
INSULINOMA	1
Insulin autoimmune syndrome	1
Injection site oedema	1
Injection site inflammation	1
Injection site infection	1
Injection site haemorrhage	1
Injection site cellulitis	1
Injection site abscess	1
Initial insomnia	1
Inhibitory drug interaction	1
INGUINAL HERNIA REPAIR	1
Infusion site vesicles	1
Infusion site swelling	1
Infusion site pruritus	1
Infusion site infection	1
Infusion site induration	1
Infusion site abscess	1
Infertility female	1
Infective exacerbation of chronic obstructive airways disease	1
Infectious mononucleosis	1
Infectious colitis	1
Infected skin ulcer	1
Increased tendency to bruise	1
Increased appetite	1
Incorrect product storage	1
INCORRECT DRUG ADMINISTRATION DURATION	1
Incorrect dosage administered	1
Incision site pain	1
IMPULSIVE BEHAVIOUR	1
IMPRISONMENT	1
ILIAC ARTERY OCCLUSION	1
IATROGENIC INJURY	1
HYPOVOLAEMIC SHOCK	1
HYPOTONIA	1
HYPOTHALAMO-PITUITARY DISORDERS	1
HYPOSPERMIA	1
Hypospadias	1
Hypoplastic left heart syndrome	1
HYPOPITUITARISM	1
Hypophagia	1
Hypomenorrhoea	1
HYPOKINESIA	1
HYPOGEUSIA	1
HYPOAESTHESIA EYE	1
Hypervolaemia	1
Hypertransaminasaemia	1
Hypertonia	1
Hyperthermia	1
HYPERTENSIVE CARDIOMYOPATHY	1
HYPERSPLENISM	1
Hyperreflexia	1
HYPERPYREXIA	1
Hyperprolactinaemia	1
HYPERPHAGIA	1
HYPERPARATHYROIDISM	1
Hyperlactacidaemia	1
HYPERDYNAMIC PRECORDIUM	1
Hyperchloraemia	1
Hyperaesthesia	1
Hospice care	1
HORNER'S SYNDROME	1
Hormone level abnormal	1
HODGKIN'S DISEASE	1
Histamine level increased	1
HIGH DENSITY LIPOPROTEIN DECREASED	1
HERPES SIMPLEX SEROLOGY POSITIVE	1
HERPES SIMPLEX	1
HERPES OPHTHALMIC	1
HERNIA HIATUS REPAIR	1
HEREDITARY ANGIOEDEMA	1
HEPATORENAL FAILURE	1
HEPATOCELLULAR DAMAGE	1
HEPATITIS B ANTIBODY	1
HEPATIC TRAUMA	1
HEPATIC PAIN	1
HEPATIC NEOPLASM	1
Hepatic necrosis	1
Hepatic lesion	1
Hepatic infection	1
HEPATIC HAEMORRHAGE	1
Hepatic cytolysis	1
HEPATIC ATROPHY	1
HEMIPLEGIA TRANSIENT	1
Helicobacter infection	1
Heart disease congenital	1
HEART AND LUNG TRANSPLANT	1
Head and neck cancer	1
Harlequin skin reaction	1
Hangnail	1
Hand-eye coordination impaired	1
Hand amputation	1
HALLUCINATION, TACTILE	1
Hallucination, auditory	1
Hairy cell leukaemia	1
Hair texture abnormal	1
HAEMORRHAGIC ASCITES	1
Haemoperitoneum	1
Haemoglobinaemia	1
HAEMOCHROMATOSIS	1
HAEMOBILIA	1
Haematocrit abnormal	1
HAEMANGIOMA OF LIVER	1
GROIN INFECTION	1
GRIP STRENGTH DECREASED	1
Graft infection	1
Glossitis	1
GLOMERULONEPHRITIS MEMBRANOUS	1
GLOMERULONEPHRITIS MEMBRANOPROLIFERATIVE	1
GLOMERULONEPHRITIS	1
GLIOBLASTOMA	1
Gingival swelling	1
Gingival pain	1
GENITAL HYPOAESTHESIA	1
Genital herpes simplex	1
Genital haemorrhage	1
Gastrointestinal wall thickening	1
GASTROINTESTINAL TUBE INSERTION	1
GASTROINTESTINAL TELANGIECTASIA	1
GASTROINTESTINAL OEDEMA	1
Gastrointestinal obstruction	1
GASTROINTESTINAL NECROSIS	1
Gastrointestinal melanosis	1
GASTROINTESTINAL CARCINOMA	1
Gastrointestinal arteriovenous malformation	1
Gastrointestinal angiodysplasia haemorrhagic	1
Gastrointestinal angiodysplasia	1
GASTROENTERITIS CLOSTRIDIAL	1
GASTRIC VARICES HAEMORRHAGE	1
Gastric varices	1
GASTRIC POLYPS	1
GASTRIC OPERATION	1
GALLBLADDER OPERATION	1
GAIT SPASTIC	1
FURUNCLE	1
Fungal oesophagitis	1
Functional gastrointestinal disorder	1
Full blood count increased	1
Full blood count abnormal	1
FRUSTRATION	1
Frostbite	1
Fractured ischium	1
Fractured coccyx	1
FOREIGN BODY TRAUMA	1
Forced vital capacity decreased	1
Foot amputation	1
Foetal death	1
FLAT AFFECT	1
FLASHBACK	1
Fistula	1
Fibula fracture	1
Fibroma	1
Femoral neck fracture	1
FEMORAL ARTERIAL STENOSIS	1
Feeling of despair	1
Feeling drunk	1
Fear of disease	1
FAT EMBOLISM	1
FALLOT'S TETRALOGY	1
FAILURE OF IMPLANT	1
Faeces soft	1
FACIAL NERVE DISORDER	1
EYELID CYST	1
EYE REDNESS	1
Eye operation	1
Eye opacity	1
EYE OEDEMA	1
Eye colour change	1
Exudative retinopathy	1
Extravasation	1
Extraocular muscle paresis	1
EXTRANODAL MARGINAL ZONE B-CELL LYMPHOMA (MALT TYPE)	1
Exposure via ingestion	1
EXPOSURE TO CHEMICAL POLLUTION	1
EXCESSIVE MASTURBATION	1
ESSENTIAL HYPERTENSION	1
Escherichia urinary tract infection	1
ESCHERICHIA TEST POSITIVE	1
Escherichia infection	1
Escherichia bacteraemia	1
EPSTEIN-BARR VIRUS ANTIBODY POSITIVE	1
EPSTEIN-BARR VIRUS ANTIBODY	1
EPIDERMOLYSIS	1
EPICONDYLITIS	1
EOSINOPHILIC PNEUMONIA	1
Eosinophil percentage increased	1
Enzyme level increased	1
ENTEROCOLITIS INFECTIOUS	1
ENTEROCOLITIS	1
ENTEROCOCCUS TEST POSITIVE	1
ENTEROCOCCAL INFECTION	1
Enterobacter sepsis	1
Enteritis infectious	1
ENLARGED CLITORIS	1
ENDOMETRIAL HYPERTROPHY	1
Endolymphatic hydrops	1
ENDOCRINE DISORDER	1
ENDARTERECTOMY	1
Empyema	1
EMBOLISM ARTERIAL	1
Elschnig's bodies	1
ELEVATED MOOD	1
ELECTROENCEPHALOGRAM ABNORMAL	1
ELECTROCARDIOGRAM ST-T SEGMENT ABNORMAL	1
ELECTROCARDIOGRAM ST SEGMENT ABNORMAL	1
Electrocardiogram repolarisation abnormality	1
ELECTROCARDIOGRAM QT CORRECTED INTERVAL PROLONGED	1
ELECTROCARDIOGRAM PR PROLONGATION	1
Electrocardiogram J wave increased	1
ELECTROCARDIOGRAM CHANGE	1
Electric shock sensation	1
Eisenmenger's syndrome	1
ECTOPIC PREGNANCY	1
ECONOMIC PROBLEM	1
Early satiety	1
EAR NEOPLASM MALIGNANT	1
Ear malformation	1
EAR INJURY	1
EAR INFECTION VIRAL	1
Ear canal erythema	1
Dyspnoea at rest	1
Dysplastic naevus	1
Dysphemia	1
Dysmenorrhoea	1
DUODENAL ULCER HAEMORRHAGE	1
Dry gangrene	1
Dry age-related macular degeneration	1
Drug tolerance increased	1
DRUG TOLERANCE DECREASED	1
Drug screen false positive	1
DRUG LEVEL DECREASED	1
DRUG LEVEL CHANGED	1
DRUG LEVEL BELOW THERAPEUTIC	1
Drug effect variable	1
Drop attacks	1
Documented hypersensitivity to administered drug	1
Dizziness postural	1
Diverticulum intestinal haemorrhagic	1
DISTAL ILEAL OBSTRUCTION SYNDROME	1
DISSOCIATIVE IDENTITY DISORDER	1
DISORDER OF ORBIT	1
DISLOCATION OF JOINT PROSTHESIS	1
DISABILITY	1
DIGITAL ULCER	1
Diet refusal	1
Diarrhoea haemorrhagic	1
DIAPHRAGMATIC PARALYSIS	1
DIAPHRAGMALGIA	1
Dialysis related complication	1
DIABETIC RETINAL OEDEMA	1
Diabetic ketoacidosis	1
DIABETIC GLAUCOMA	1
Diabetic foot infection	1
DIABETIC EYE DISEASE	1
Device dislocation	1
Device defective	1
Device damage	1
Device computer issue	1
Device battery issue	1
Dermoid cyst	1
DERMATITIS ATOPIC	1
DERMAL CYST	1
DEPOSIT EYE	1
Dependence on oxygen therapy	1
DEPENDENCE	1
Dental pulp disorder	1
Dental discomfort	1
Dental caries	1
DELUSIONAL DISORDER, PERSECUTORY TYPE	1
Deformity	1
DECUBITUS ULCER	1
DECREASED VENTRICULAR PRELOAD	1
DECREASED EYE CONTACT	1
Decreased activity	1
DECEREBRATION	1
DEAFNESS TRAUMATIC	1
DEAFNESS PERMANENT	1
Daydreaming	1
Cytotoxic oedema	1
Cystoid macular oedema	1
Cystitis haemorrhagic	1
CUTIS LAXA	1
CUTANEOUS VASCULITIS	1
CUSHINGOID	1
CSF PRESSURE INCREASED	1
CRYPTOGENIC ORGANIZING PNEUMONIA	1
Cross sensitivity reaction	1
COVID-19 pneumonia	1
COUNTERFEIT DRUG ADMINISTERED	1
Coronavirus infection	1
CORONARY OSTIAL STENOSIS	1
CORONARY ARTERY SURGERY	1
CORONARY ARTERY INSUFFICIENCY	1
CORONARY ARTERY BYPASS	1
CORONARY ARTERY ATHEROSCLEROSIS	1
Cor pulmonale acute	1
CONNECTIVE TISSUE DISORDER	1
Conjunctival melanoma	1
CONJUNCTIVAL BLEB	1
Congestive hepatopathy	1
Congenital pneumonia	1
CONGENITAL MITRAL VALVE STENOSIS	1
Congenital diaphragmatic hernia	1
Congenital coronary artery malformation	1
CONGENITAL ARTERIAL MALFORMATION	1
CONGENITAL ANOMALY	1
CONFABULATION	1
Complications of transplanted liver	1
COMPLICATIONS OF TRANSPLANT SURGERY	1
COMPLICATION OF PREGNANCY	1
COMPLICATED MIGRAINE	1
Complex regional pain syndrome	1
Combined pulmonary fibrosis and emphysema	1
Coma scale abnormal	1
COMA HEPATIC	1
COLOUR VISION TESTS ABNORMAL	1
Colostomy	1
Colonoscopy	1
COLON GANGRENE	1
Colon cancer stage IV	1
COLON CANCER RECURRENT	1
Colon cancer metastatic	1
COLLAGEN DISORDER	1
Colitis microscopic	1
COELIAC DISEASE	1
COARCTATION OF THE AORTA	1
CLUBBING	1
Clostridium test positive	1
CLOSED HEAD INJURY	1
CLONIC CONVULSION	1
CLITORAL ENGORGEMENT	1
Cleft palate	1
Claudication of jaw muscles	1
CIRRHOSIS ALCOHOLIC	1
CIRCUMORAL OEDEMA	1
Chylothorax	1
CHRONIC SINUSITIS	1
CHRONIC OBSTRUCTIVE AIRWAYS DISEASE	1
Chronic hepatitis	1
CHOROIDAL NAEVUS	1
CHOROIDAL DETACHMENT	1
CHORIORETINAL SCAR	1
CHORIORETINAL ATROPHY	1
Chondropathy	1
CHOLANGITIS	1
Cholangiocarcinoma	1
Choking sensation	1
Chlamydial infection	1
Chest wall haematoma	1
Chemical injury	1
CHALAZION	1
Cervical spinal stenosis	1
CERUMEN IMPACTION	1
CEREBROVASCULAR STENOSIS	1
Cerebrovascular insufficiency	1
Cerebral ventricle dilatation	1
Cerebral cyst	1
CEREBRAL ATHEROSCLEROSIS	1
CEREBRAL ARTERY EMBOLISM	1
Cerebral arteriosclerosis	1
CEREBELLAR ISCHAEMIA	1
CEREBELLAR ATROPHY	1
Central nervous system melanoma	1
CENTRAL NERVOUS SYSTEM LESION	1
Central cord syndrome	1
Cellulitis staphylococcal	1
Cell marker increased	1
CATHETERISATION CARDIAC ABNORMAL	1
Catheter site swelling	1
Catheter site scab	1
Catheter site rash	1
Catheter site pruritus	1
Catheter site inflammation	1
Catheter site discharge	1
Catheter site cellulitis	1
CATHETER PLACEMENT	1
CATARACT SUBCAPSULAR	1
CATARACT OPERATION	1
Carotid artery thrombosis	1
Cardiovascular evaluation	1
CARDIOACTIVE DRUG LEVEL INCREASED	1
Cardio-respiratory arrest neonatal	1
Cardiac ventricular thrombosis	1
Cardiac septal hypertrophy	1
Cardiac septal defect	1
CARDIAC PROCEDURE COMPLICATION	1
Cardiac pacemaker replacement	1
Cardiac infection	1
Cardiac function test abnormal	1
Cardiac device reprogramming	1
Cardiac cirrhosis	1
CARDIAC ANEURYSM	1
Cardiac ablation	1
CARCINOEMBRYONIC ANTIGEN INCREASED	1
Carbon monoxide diffusing capacity decreased	1
CARBON DIOXIDE DECREASED	1
CARBON DIOXIDE ABNORMAL	1
Capillary fragility	1
Candida infection	1
Cancer surgery	1
Calculus urethral	1
CACHEXIA	1
C-REACTIVE PROTEIN ABNORMAL	1
BURNS SECOND DEGREE	1
BURN OESOPHAGEAL	1
Buccal mucosal roughening	1
Bronchitis chronic	1
BRONCHITIS BACTERIAL	1
BRONCHITIS ACUTE	1
Breast tumour excision	1
Breast swelling	1
Breast neoplasm	1
Breast mass	1
BREAST DISCHARGE	1
Breast cyst	1
Breast cancer recurrent	1
Breast cancer male	1
BRAIN STEM INFARCTION	1
BRAIN STEM HAEMORRHAGE	1
Brain death	1
Brain abscess	1
Bradykinesia	1
Bradycardia neonatal	1
BOWEL SOUNDS ABNORMAL	1
BOWEL MOVEMENT IRREGULARITY	1
BORRELIA INFECTION	1
BONE NEOPLASM	1
Bone marrow transplant	1
BONE MARROW TOXICITY	1
Bone marrow oedema	1
Bone loss	1
BONE GRAFT	1
BODY MASS INDEX INCREASED	1
Body fat disorder	1
Blood viscosity increased	1
BLOOD UREA NITROGEN/CREATININE RATIO INCREASED	1
Blood thyroid stimulating hormone decreased	1
Blood testosterone free decreased	1
BLOOD SODIUM INCREASED	1
Blood prolactin increased	1
BLOOD PRESSURE SYSTOLIC ABNORMAL	1
Blood pressure normal	1
BLOOD PRESSURE IMMEASURABLE	1
BLOOD PRESSURE DIASTOLIC INCREASED	1
BLOOD POTASSIUM ABNORMAL	1
Blood parathyroid hormone increased	1
BLOOD OSMOLARITY INCREASED	1
Blood oestrogen increased	1
BLOOD LUTEINISING HORMONE DECREASED	1
Blood loss anaemia	1
BLOOD LACTIC ACID INCREASED	1
Blood glucose fluctuation	1
BLOOD GLUCOSE	1
BLOOD FOLLICLE STIMULATING HORMONE INCREASED	1
BLOOD ETHANOL INCREASED	1
Blood electrolytes abnormal	1
Blood creatinine abnormal	1
Blood creatine phosphokinase decreased	1
Blood creatine decreased	1
Blood creatine abnormal	1
Blood cortisol decreased	1
BLOOD CHOLINESTERASE DECREASED	1
Blood cholesterol abnormal	1
BLOOD CHLORIDE INCREASED	1
BLOOD CATECHOLAMINES ABNORMAL	1
BLOOD CALCIUM INCREASED	1
Blood calcium abnormal	1
BLOOD CAFFEINE INCREASED	1
BLOOD BILIRUBIN UNCONJUGATED INCREASED	1
Blood bilirubin abnormal	1
BLOOD BICARBONATE DECREASED	1
BLOOD AMYLASE INCREASED	1
Blood alkaline phosphatase decreased	1
Blister rupture	1
BLINDNESS CORTICAL	1
BLIGHTED OVUM	1
BLEPHAROSPASM	1
Bleeding varicose vein	1
BLADDER OBSTRUCTION	1
BLADDER NECK OBSTRUCTION	1
Bladder irritation	1
Bladder dysfunction	1
BLADDER DILATATION	1
Bipolar I disorder	1
Biliary tract infection	1
BILIARY CYST	1
Biliary cirrhosis primary	1
Biliary cirrhosis	1
Bile duct cancer	1
BENIGN BONE NEOPLASM	1
Behaviour disorder	1
Basophil count increased	1
BASAL GANGLIA STROKE	1
BARRETT'S OESOPHAGUS	1
BALANITIS	1
Bacteriuria	1
Bacterial sepsis	1
B-cell small lymphocytic lymphoma	1
Autoimmune haemolytic anaemia	1
Autism spectrum disorder	1
Aura	1
Atrial pressure increased	1
ATHEROSCLEROSIS	1
ASPIRATION BRONCHIAL	1
ASPERMIA	1
Aspergillus test positive	1
Aspergillus infection	1
ASPERGILLOSIS	1
ASPARTATE AMINOTRANSFERASE DECREASED	1
ARTHROSCOPIC SURGERY	1
Arthritis bacterial	1
Artery dissection	1
Arterial thrombosis	1
Arterial rupture	1
Arterial haemorrhage	1
ARTERIAL BYPASS OPERATION	1
Arrhythmogenic right ventricular dysplasia	1
Areflexia	1
ARACHNOID CYST	1
Apraxia	1
Appetite disorder	1
Apparent death	1
APLASTIC ANAEMIA	1
APLASIA PURE RED CELL	1
AORTIC VALVE STENOSIS	1
Aortic valve incompetence	1
Aortic valve disease	1
AORTIC SURGERY	1
AORTIC DISORDER	1
AORTIC CALCIFICATION	1
AORTIC ATHEROSCLEROSIS	1
AORTIC ANEURYSM RUPTURE	1
Antisynthetase syndrome	1
Antisocial behaviour	1
ANTINUCLEAR ANTIBODY INCREASED	1
ANTICONVULSANT DRUG LEVEL DECREASED	1
ANTI-ERYTHROPOIETIN ANTIBODY POSITIVE	1
ANTERIOR CHAMBER DISORDER	1
ANOXIA	1
ANOSMIA	1
ANORECTAL DISORDER	1
ANOGENITAL WARTS	1
Ankyloglossia congenital	1
ANISOCYTOSIS	1
Animal scratch	1
Animal bite	1
ANHEDONIA	1
ANGIOTENSIN CONVERTING ENZYME DECREASED	1
Angiosarcoma	1
ANGIOPLASTY	1
ANGIOGRAM ABNORMAL	1
Angiogram	1
Angiodysplasia	1
Anginal equivalent	1
ANDROPAUSE	1
Androgen deficiency	1
ANASTOMOTIC STENOSIS	1
Anal incontinence	1
Anaemia neonatal	1
ANAEMIA MACROCYTIC	1
Amylase increased	1
Amniotic fluid volume increased	1
ALTERED VISUAL DEPTH PERCEPTION	1
ALPHA 2 GLOBULIN DECREASED	1
Allergic reaction to excipient	1
Alcoholism	1
ALCOHOL WITHDRAWAL SYNDROME	1
ALCOHOL DETOXIFICATION	1
Akathisia	1
AGRANULOCYTOSIS	1
Agoraphobia	1
AGONAL RHYTHM	1
Ageusia	1
Aerophagia	1
Adrenomegaly	1
ADRENAL NEOPLASM	1
Adrenal haemorrhage	1
Adrenal disorder	1
ADRENAL ADENOMA	1
ADMINISTRATION SITE PAIN	1
ADJUSTMENT DISORDER WITH DEPRESSED MOOD	1
ADENOMA BENIGN	1
Adenocarcinoma of colon	1
ACUTE STRESS DISORDER	1
Acute prerenal failure	1
ACUTE MYELOMONOCYTIC LEUKAEMIA	1
Acute myeloid leukaemia	1
ACUTE LYMPHOCYTIC LEUKAEMIA	1
Acute abdomen	1
ACTIVATED PARTIAL THROMBOPLASTIN TIME ABNORMAL	1
ACROCHORDON	1
Acral lentiginous melanoma stage III	1
ACQUIRED DIAPHRAGMATIC EVENTRATION	1
ACOUSTIC NEUROMA	1
ACOUSTIC NEURITIS	1
Acetabulum fracture	1
Accidental death	1
Abscess limb	1
Abscess drainage	1
Abscess	1
ABORTION INDUCED	1
Abnormal weight gain	1
Abnormal loss of weight	1
Abnormal faeces	1
ABDOMINAL TENDERNESS	1
ABDOMINAL SYMPTOM	1
ABDOMINAL STRANGULATED HERNIA	1
Abdominal infection	1

Filtered ChEMBL targets:

Target UniProtKB ID	Activity in nm	Target Name	Target gene
O15440	1200	Multidrug resistance-associated protein 5	MRP5_HUMAN
O76074	1	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE5A_HUMAN
O76083	3400	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	PDE9A_HUMAN
P27815	5000	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	PDE4A_HUMAN
P29274	199.53	Adenosine receptor A2a	AA2AR_HUMAN
P51160	24	Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	PDE6C_HUMAN
P54750	600	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	PDE1A_HUMAN
Q12809	3300	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN
Q13946	4690	High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	PDE7A_HUMAN
Q9HCR9	2300	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	PDE11_HUMAN
Q9Y233	3100	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	PDE10_HUMAN

Toxicity information:

Toxicity type:	N/A

External links:

ChEBML:	CHEMBL192
DrugBank:	DB00203