parecoxib
General information:
| Withdrawn ID: | EMA32 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | M01AH04 |
| Molecular Formula: | C19H18N2O4S |
| Molweight: | 370.422 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | No |
|---|
Side-effects:
| Total reported cases (submitted by medical professionals) with parecoxib as primary suspect: | 5 |
|---|
Reported final outcomes:
| Hospitalization (initial or prolonged): | 2 |
|---|---|
| Death: | 1 |
Reported side-effects:
| Side-effect | Case number |
|---|---|
| Liver abscess | 1 |
| URETHRAL PAIN | 1 |
| Transaminases increased | 1 |
| STEVENS-JOHNSON SYNDROME | 1 |
| Septic shock | 1 |
| Sepsis | 1 |
| RENAL FAILURE ACUTE | 1 |
| Rash | 1 |
| NAUSEA | 1 |
| MYOCARDIAL INFARCTION | 1 |
| Bilirubin conjugated abnormal | 1 |
| Hypotension | 1 |
| Haemoglobin decreased | 1 |
| Gastroduodenal haemorrhage | 1 |
| DYSPHAGIA | 1 |
| Cardiac failure | 1 |
| CARDIAC ARREST | 1 |
| BLOOD PRESSURE DECREASED | 1 |
| Blood bilirubin unconjugated increased | 1 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| P35354 | 5 | Prostaglandin G/H synthase 2 | PGH2_HUMAN |
Toxicity information:
| Toxicity type: | N/A |
|---|
External links:
| ChEBML: | CHEMBL1206690 |
|---|---|
| DrugBank: | DB08439 |