aliskiren


EMA2



General information:


Withdrawn ID: EMA2
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es): C09XA02
Molecular Formula: C30H53N3O6
Molweight: 551.758



Withdrawal information:


Withdrawn due to drug safety reasons:No



Side-effects:

Total reported cases (submitted by medical professionals) with aliskiren as primary suspect: 3577


Reported final outcomes:
Hospitalization (initial or prolonged): 1364
Death: 347
Life-Threatening condition: 230
Disability: 91
Congenital anomaly: 7
Intervention required to prevent permanent impairment/damage: 1


Reported side-effects:

Side-effect Case number
BLOOD CREATININE INCREASED312
DYSPNOEA251
BLOOD PRESSURE INCREASED202
RENAL FAILURE179
HYPERKALAEMIA161
ANGIOEDEMA159
DIZZINESS153
RENAL FAILURE ACUTE153
HYPOTENSION150
HYPERTENSION148
RENAL IMPAIRMENT146
CEREBROVASCULAR ACCIDENT131
OEDEMA PERIPHERAL131
DIARRHOEA130
CARDIAC FAILURE127
MALAISE121
HEADACHE112
BLOOD UREA INCREASED111
NAUSEA107
HYPONATRAEMIA97
VOMITING97
DEATH92
FATIGUE89
ASTHENIA86
BLOOD POTASSIUM INCREASED86
BLOOD PRESSURE INADEQUATELY CONTROLLED84
DRUG INEFFECTIVE80
RASH80
CHEST PAIN79
SYNCOPE78
COUGH73
OEDEMA72
ATRIAL FIBRILLATION71
DEHYDRATION71
FALL70
DIABETES MELLITUS66
PRURITUS66
ABDOMINAL PAIN62
Concomitant disease progression62
DRUG INTERACTION62
BLOOD PRESSURE DECREASED61
ANAEMIA59
ANGINA PECTORIS58
PYREXIA57
PROTEINURIA56
DYSPHAGIA55
GLYCOSYLATED HAEMOGLOBIN INCREASED55
LOSS OF CONSCIOUSNESS55
GLOMERULAR FILTRATION RATE DECREASED54
HAEMOGLOBIN DECREASED54
FEELING ABNORMAL53
PNEUMONIA53
RENAL FAILURE CHRONIC52
BRADYCARDIA50
BLOOD GLUCOSE INCREASED48
DISEASE PROGRESSION48
WEIGHT DECREASED48
BLOOD PRESSURE SYSTOLIC INCREASED47
Decreased appetite47
PALPITATIONS46
HYPERTENSIVE CRISIS45
SWELLING FACE45
SWOLLEN TONGUE45
ARRHYTHMIA44
BLOOD PRESSURE DIASTOLIC DECREASED44
CONDITION AGGRAVATED44
CHEST DISCOMFORT43
CONFUSIONAL STATE43
CARDIAC FAILURE CONGESTIVE42
PAIN42
ARTHRALGIA41
MYALGIA41
TACHYCARDIA41
URINE ALBUMIN/CREATININE RATIO INCREASED41
HYPOKALAEMIA40
ERYTHEMA39
LIP SWELLING39
MYOCARDIAL INFARCTION38
WEIGHT INCREASED38
PHARYNGEAL OEDEMA37
CORONARY ARTERY DISEASE36
GAMMA-GLUTAMYLTRANSFERASE INCREASED36
HYPERHIDROSIS36
PAIN IN EXTREMITY36
URINARY TRACT INFECTION36
GAIT DISTURBANCE35
TRANSIENT ISCHAEMIC ATTACK35
ANXIETY34
HEART RATE INCREASED34
MUSCULAR WEAKNESS34
ALANINE AMINOTRANSFERASE INCREASED33
URTICARIA32
DEPRESSION31
DYSARTHRIA31
PLEURAL EFFUSION31
PULMONARY OEDEMA31
FACE OEDEMA30
Acute kidney injury29
ASPARTATE AMINOTRANSFERASE INCREASED29
BACK PAIN29
Chronic kidney disease29
CARDIAC ARREST28
HYPERSENSITIVITY28
ACUTE MYOCARDIAL INFARCTION27
PARAESTHESIA27
LEFT VENTRICULAR HYPERTROPHY26
RENAL DISORDER26
VERTIGO26
PERIORBITAL OEDEMA25
HAEMATOCRIT DECREASED24
C-REACTIVE PROTEIN INCREASED23
RENAL ARTERY STENOSIS23
SOMNOLENCE23
TREMOR23
CEREBRAL INFARCTION22
CONVULSION22
DIABETIC NEPHROPATHY22
MITRAL VALVE INCOMPETENCE22
RASH GENERALISED22
VENTRICULAR TACHYCARDIA22
ABDOMINAL DISCOMFORT21
ABDOMINAL PAIN UPPER21
CHRONIC OBSTRUCTIVE PULMONARY DISEASE21
CREATININE RENAL CLEARANCE DECREASED21
EYELID OEDEMA21
HEART RATE DECREASED21
INFECTION21
ASTHMA20
GENERAL PHYSICAL HEALTH DETERIORATION20
HYPOGLYCAEMIA20
SWELLING20
ABDOMINAL DISTENSION19
JAUNDICE19
MUSCLE SPASMS19
POLLAKIURIA19
ANAPHYLACTIC REACTION18
BLOOD CREATINE PHOSPHOKINASE INCREASED18
CARDIO-RESPIRATORY ARREST18
MYOCARDIAL ISCHAEMIA18
RESPIRATORY FAILURE18
SEPSIS18
SLEEP DISORDER18
THROMBOCYTOPENIA18
TYPE 2 DIABETES MELLITUS18
URINE OUTPUT DECREASED18
BLOOD POTASSIUM DECREASED17
BLOOD SODIUM DECREASED17
BLOOD URIC ACID INCREASED17
CARDIOMEGALY17
GOUT17
HEPATIC ENZYME INCREASED17
WHITE BLOOD CELL COUNT INCREASED17
BRAIN NATRIURETIC PEPTIDE INCREASED16
CARDIAC FAILURE ACUTE16
DIALYSIS16
DYSPNOEA EXERTIONAL16
INSOMNIA16
ORTHOPNOEA16
ORTHOSTATIC HYPOTENSION16
SUDDEN CARDIAC DEATH16
BLOOD PRESSURE FLUCTUATION15
CARDIOGENIC SHOCK15
CIRCULATORY COLLAPSE15
CONSTIPATION15
GASTROINTESTINAL HAEMORRHAGE15
GASTROOESOPHAGEAL REFLUX DISEASE15
GENERALISED OEDEMA15
HAEMATURIA15
HEMIPARESIS15
Hepatic function abnormal15
Hepatic steatosis15
HYPOVOLAEMIA15
JOINT SWELLING15
LETHARGY15
LIP OEDEMA15
OLIGURIA15
PANCREATITIS15
PLATELET COUNT DECREASED15
PULMONARY CONGESTION15
PULMONARY EMBOLISM15
VENTRICULAR EXTRASYSTOLES15
VISION BLURRED15
BLOOD BILIRUBIN INCREASED14
BRONCHITIS14
CARDIAC DISORDER14
DRY MOUTH14
DYSURIA14
EXTRASYSTOLES14
FLUID RETENTION14
MICROALBUMINURIA14
RENIN INCREASED14
SLEEP APNOEA SYNDROME14
THROAT TIGHTNESS14
TRICUSPID VALVE INCOMPETENCE14
BLISTER13
BLOOD CREATINE INCREASED13
BURNING SENSATION13
CEREBRAL HAEMORRHAGE13
DIABETES MELLITUS INADEQUATE CONTROL13
ELECTROCARDIOGRAM QT PROLONGED13
HAEMORRHAGE13
HYPOAESTHESIA13
Left ventricular dysfunction13
LIVER FUNCTION TEST ABNORMAL13
METABOLIC ACIDOSIS13
NASOPHARYNGITIS13
ROAD TRAFFIC ACCIDENT13
TONGUE OEDEMA13
TOXIC SKIN ERUPTION13
AGITATION12
ALOPECIA12
APHASIA12
CONTUSION12
DYSPEPSIA12
Electrocardiogram QRS complex prolonged12
EOSINOPHILIA12
GASTROENTERITIS12
GASTROINTESTINAL DISORDER12
HYPERLIPIDAEMIA12
INFLAMMATION12
INTERSTITIAL LUNG DISEASE12
NEPHROPATHY12
NERVOUSNESS12
OEDEMA MOUTH12
Presyncope12
RED BLOOD CELL COUNT DECREASED12
SURGERY12
ACUTE CORONARY SYNDROME11
ACUTE PULMONARY OEDEMA11
ATRIOVENTRICULAR BLOCK11
AZOTAEMIA11
BLOOD TRIGLYCERIDES INCREASED11
CARDIOMYOPATHY11
CATARACT11
CHILLS11
EJECTION FRACTION DECREASED11
FLUSHING11
INJURY11
LUNG DISORDER11
Pancreatitis acute11
PRODUCTIVE COUGH11
PULMONARY FIBROSIS11
RHABDOMYOLYSIS11
VENTRICULAR FIBRILLATION11
WHEEZING11
ANURIA10
BLOOD ALKALINE PHOSPHATASE INCREASED10
BLOOD PRESSURE ABNORMAL10
CONJUNCTIVAL HAEMORRHAGE10
CYSTITIS10
DISORIENTATION10
DRUG HYPERSENSITIVITY10
HEPATITIS10
LEUKOCYTOSIS10
LIPASE INCREASED10
NEPHROTIC SYNDROME10
OBESITY10
ODYNOPHAGIA10
PALLOR10
PETECHIAE10
Prostate cancer10
RESPIRATORY DISORDER10
SPEECH DISORDER10
SUDDEN DEATH10
TACHYARRHYTHMIA10
URINARY INCONTINENCE10
ARTHRITIS9
ASCITES9
BALANCE DISORDER9
BLOOD CHOLESTEROL INCREASED9
BRAIN OEDEMA9
Cardiac failure chronic9
CONCOMITANT DISEASE AGGRAVATED9
ECZEMA9
EYE SWELLING9
FEELING COLD9
FEELING HOT9
FLANK PAIN9
HALLUCINATION9
HEMIPLEGIA9
HEPATIC FAILURE9
HEPATOMEGALY9
HOT FLUSH9
Hypothyroidism9
LOCAL SWELLING9
MULTI-ORGAN FAILURE9
MUSCULOSKELETAL PAIN9
NASAL CONGESTION9
OSTEOARTHRITIS9
PRURITUS GENERALISED9
PULMONARY HYPERTENSION9
RALES9
RASH PRURITIC9
RENAL CYST9
SKIN DISCOLOURATION9
STRESS9
TACHYPNOEA9
VISUAL ACUITY REDUCED9
VISUAL IMPAIRMENT9
Wrong technique in product usage process9
ANGINA UNSTABLE8
BLOOD LACTATE DEHYDROGENASE INCREASED8
BLOOD PRESSURE DIASTOLIC INCREASED8
BLOOD PRESSURE SYSTOLIC DECREASED8
BRONCHOSPASM8
BUNDLE BRANCH BLOCK LEFT8
CHOLELITHIASIS8
DERMATITIS ALLERGIC8
DRUG INTOLERANCE8
DYSPHONIA8
ELECTROLYTE IMBALANCE8
EYE DISORDER8
Foetal exposure during pregnancy8
HAEMATOCHEZIA8
HAEMORRHOIDS8
HEAD INJURY8
HYPERGLYCAEMIA8
HYPERPARATHYROIDISM SECONDARY8
HYPERTRIGLYCERIDAEMIA8
HYPERURICAEMIA8
HYPOPHAGIA8
INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION8
ISCHAEMIC STROKE8
LIVER DISORDER8
LYMPHADENOPATHY8
MENTAL STATUS CHANGES8
MUSCULOSKELETAL STIFFNESS8
PANCYTOPENIA8
PARAESTHESIA ORAL8
Peripheral swelling8
PHOTOSENSITIVITY REACTION8
Product use issue8
RASH MACULO-PAPULAR8
SINUS TACHYCARDIA8
SKIN DISORDER8
SUPRAVENTRICULAR TACHYCARDIA8
THROMBOSIS8
VIITH NERVE PARALYSIS8
WRONG TECHNIQUE IN DRUG USAGE PROCESS8
Anhedonia7
AORTIC STENOSIS7
BLOOD ALBUMIN DECREASED7
BLOOD GLUCOSE DECREASED7
BRONCHOPNEUMONIA7
Carotid artery stenosis7
COMA7
CREATININE URINE INCREASED7
DERMATITIS7
DERMATITIS BULLOUS7
DIASTOLIC DYSFUNCTION7
DRUG ERUPTION7
Drug-induced liver injury7
Dyslipidaemia7
ELECTROCARDIOGRAM ABNORMAL7
EPISTAXIS7
FLATULENCE7
Gastric ulcer7
GYNAECOMASTIA7
HAEMATEMESIS7
LACTIC ACIDOSIS7
LIMB DISCOMFORT7
LUNG NEOPLASM MALIGNANT7
MENTAL DISORDER7
NEUTROPHIL COUNT INCREASED7
OROPHARYNGEAL PAIN7
PERICARDIAL EFFUSION7
POLYURIA7
RASH ERYTHEMATOUS7
RENAL PAIN7
RENAL TUBULAR NECROSIS7
SHOCK7
SKIN EXFOLIATION7
SKIN LESION7
SKIN ULCER7
STRIDOR7
THIRST7
THROAT IRRITATION7
TINNITUS7
VASCULITIS7
ACUTE PRERENAL FAILURE6
ALBUMIN URINE PRESENT6
AMNESIA6
Aortic valve incompetence6
ARTERIOSCLEROSIS6
ATRIAL FLUTTER6
ATRIOVENTRICULAR BLOCK COMPLETE6
ATRIOVENTRICULAR BLOCK FIRST DEGREE6
BLOOD UREA DECREASED6
BRADYARRHYTHMIA6
CELLULITIS6
CONGESTIVE CARDIOMYOPATHY6
CORONARY ARTERY STENOSIS6
CYANOSIS6
DEPRESSED LEVEL OF CONSCIOUSNESS6
DEPRESSED MOOD6
Diabetic retinopathy6
ENDOTRACHEAL INTUBATION6
EPILEPSY6
ERECTILE DYSFUNCTION6
FRACTURE6
GASTRITIS6
HAEMATOMA6
HEPATIC NECROSIS6
HYPOTONIA6
INCORRECT DOSE ADMINISTERED6
INTERNATIONAL NORMALISED RATIO INCREASED6
IRON DEFICIENCY ANAEMIA6
KIDNEY INFECTION6
Large intestine polyp6
MALIGNANT HYPERTENSION6
MEMORY IMPAIRMENT6
MOVEMENT DISORDER6
NOCTURNAL DYSPNOEA6
PEMPHIGOID6
PERIPHERAL COLDNESS6
Pneumonia aspiration6
PROTEIN URINE PRESENT6
RASH MACULAR6
RECTAL CANCER6
RENAL FUNCTION TEST ABNORMAL6
RESPIRATORY DISTRESS6
RESUSCITATION6
RIGHT VENTRICULAR FAILURE6
SINUS BRADYCARDIA6
STENT PLACEMENT6
TREATMENT NONCOMPLIANCE6
UPPER RESPIRATORY TRACT INFECTION6
URINARY RETENTION6
VENTRICULAR HYPOKINESIA6
ABASIA5
ABNORMAL BEHAVIOUR5
ACIDOSIS5
Aneurysm5
Atrioventricular block second degree5
BLINDNESS UNILATERAL5
BLOOD ALBUMIN INCREASED5
BLOOD CALCIUM DECREASED5
BLOOD DISORDER5
Blood sodium increased5
BLOOD URINE PRESENT5
Bone marrow failure5
BREAST CANCER5
BUNDLE BRANCH BLOCK RIGHT5
CARDIAC PACEMAKER INSERTION5
CEREBELLAR INFARCTION5
CEREBRAL ISCHAEMIA5
COLON ADENOMA5
COORDINATION ABNORMAL5
CORONARY ARTERY OCCLUSION5
CREPITATIONS5
DEEP VEIN THROMBOSIS5
DELIRIUM5
DERMATITIS EXFOLIATIVE5
DIPLOPIA5
DYSGEUSIA5
EATING DISORDER5
ELECTROCARDIOGRAM T WAVE ABNORMAL5
FAECES DISCOLOURED5
FEMUR FRACTURE5
Fluid overload5
GASTRIC CANCER5
HAEMORRHAGIC STROKE5
HEPATIC CIRRHOSIS5
Hepatocellular injury5
HERPES ZOSTER5
HIATUS HERNIA5
HYPERCHOLESTEROLAEMIA5
HYPERVENTILATION5
INFARCTION5
LACERATION5
LEFT VENTRICULAR FAILURE5
LUNG INFILTRATION5
LYMPHOEDEMA5
MATERNAL EXPOSURE DURING PREGNANCY5
MELAENA5
METASTASES TO CENTRAL NERVOUS SYSTEM5
NECK PAIN5
NEOPLASM MALIGNANT5
NEPHROGENIC ANAEMIA5
NEPHROLITHIASIS5
NIGHTMARE5
NORMOCHROMIC NORMOCYTIC ANAEMIA5
OSTEOPOROSIS5
OVERDOSE5
PROTEIN TOTAL DECREASED5
Pulmonary vascular disorder5
RASH PAPULAR5
RENAL CELL CARCINOMA5
RESTLESSNESS5
SENSATION OF HEAVINESS5
SEPTIC SHOCK5
STEVENS-JOHNSON SYNDROME5
STOMATITIS5
SUICIDAL IDEATION5
THERAPEUTIC RESPONSE DECREASED5
THYROID DISORDER5
TROPONIN INCREASED5
VENTRICULAR HYPERTROPHY5
White blood cell count decreased5
ACTIVITIES OF DAILY LIVING IMPAIRED4
AGGRESSION4
ALTERED STATE OF CONSCIOUSNESS4
ARTERIAL OCCLUSIVE DISEASE4
ARTERIOSCLEROSIS CORONARY ARTERY4
ASPHYXIA4
BLINDNESS4
BLOOD CALCIUM INCREASED4
BREATH SOUNDS ABNORMAL4
CARDIAC ENZYMES INCREASED4
CARDIAC FLUTTER4
CARDIOVASCULAR DISORDER4
CEREBROVASCULAR DISORDER4
Cholecystitis4
CHROMATURIA4
COLON CANCER4
Conjoined twins4
DEMENTIA4
DILATATION ATRIAL4
DILATATION VENTRICULAR4
DISCOMFORT4
DIVERTICULUM INTESTINAL4
DROOLING4
DRUG EFFECT DECREASED4
DRUG RASH WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS4
Dyspnoea at rest4
Dyspnoea paroxysmal nocturnal4
Endocarditis4
ESCHERICHIA INFECTION4
Exposure during pregnancy4
EYE PAIN4
Faecal incontinence4
GASTRIC DISORDER4
GENERALISED ERYTHEMA4
GLOSSODYNIA4
HALLUCINATION, VISUAL4
HEART DISEASE CONGENITAL4
HEART RATE IRREGULAR4
HEAT ILLNESS4
HEPATIC CYST4
HERNIA4
HYPERNATRAEMIA4
HYPOCALCAEMIA4
HYPOCHLORAEMIA4
HYPOXIA4
INFLUENZA4
IRRITABILITY4
Ischaemic cardiomyopathy4
LEFT ATRIAL DILATATION4
LEUKOCYTOCLASTIC VASCULITIS4
LEUKOPENIA4
LUNG INFECTION4
LYMPHOMA4
MUSCLE TIGHTNESS4
MYELODYSPLASTIC SYNDROME4
MYOSITIS4
NECROSIS4
NEPHROSCLEROSIS4
NEURALGIA4
NEUROPATHY PERIPHERAL4
NODULE4
NON-CARDIAC CHEST PAIN4
Ocular icterus4
PARKINSON'S DISEASE4
PERIPHERAL ARTERIAL OCCLUSIVE DISEASE4
PIGMENTATION DISORDER4
POLYNEUROPATHY4
POST PROCEDURAL HAEMATOMA4
PURPURA4
PYELONEPHRITIS4
RASH PUSTULAR4
RENAL ATROPHY4
Respiratory arrest4
RESPIRATORY TRACT INFECTION4
RHEUMATOID ARTHRITIS4
RIB FRACTURE4
Seizure4
SENSORY LOSS4
Sinusitis4
SKIN OEDEMA4
SPINAL OSTEOARTHRITIS4
STAPHYLOCOCCAL INFECTION4
TONGUE BITING4
TORSADE DE POINTES4
Toxicity to various agents4
TRANSAMINASES INCREASED4
UPPER LIMB FRACTURE4
URINE COLOUR ABNORMAL4
Ventricular septal defect4
ABDOMINAL PAIN LOWER3
ABORTION INDUCED3
ABORTION SPONTANEOUS3
ACUTE RESPIRATORY DISTRESS SYNDROME3
ACUTE RESPIRATORY FAILURE3
AGRANULOCYTOSIS3
ALBUMINURIA3
ALVEOLITIS3
AORTIC ANEURYSM3
AORTIC ARTERIOSCLEROSIS3
AORTIC DISSECTION3
Aortic valve sclerosis3
ARTHROPATHY3
ASPIRATION3
Atelectasis3
Back injury3
BILE DUCT STONE3
Bipolar disorder3
BLOOD ALDOSTERONE INCREASED3
BLOOD CHLORIDE INCREASED3
BLOOD CREATININE ABNORMAL3
Blood glucose abnormal3
BLOOD IMMUNOGLOBULIN E INCREASED3
BONE PAIN3
BRAIN STEM INFARCTION3
CARDIAC HYPERTROPHY3
CATHETERISATION CARDIAC3
CEREBRAL ATROPHY3
CHOKING3
CHOLESTASIS3
Coagulopathy3
COLD SWEAT3
COMPUTERISED TOMOGRAM ABNORMAL3
Congenital bladder anomaly3
CORONARY ARTERIAL STENT INSERTION3
CORONARY ARTERY RESTENOSIS3
Diabetic neuropathy3
DISSEMINATED INTRAVASCULAR COAGULATION3
DIVERTICULUM3
DRUG EXPOSURE DURING PREGNANCY3
DRUG PRESCRIBING ERROR3
DRY SKIN3
ELECTROCARDIOGRAM REPOLARISATION ABNORMALITY3
EMPHYSEMA3
ENTEROCOLITIS HAEMORRHAGIC3
EOSINOPHIL COUNT INCREASED3
ERYSIPELAS3
EYE HAEMORRHAGE3
FEMORAL NECK FRACTURE3
FORCED EXPIRATORY VOLUME DECREASED3
Gastritis erosive3
GENERAL PHYSICAL CONDITION ABNORMAL3
GLAUCOMA3
GLOMERULONEPHRITIS3
GRAND MAL CONVULSION3
HAEMOLYTIC ANAEMIA3
HAEMORRHAGE INTRACRANIAL3
HEARING IMPAIRED3
HEART RATE ABNORMAL3
Hepatic congestion3
HEPATIC NEOPLASM MALIGNANT3
HEPATITIS TOXIC3
HEPATOTOXICITY3
HIGH DENSITY LIPOPROTEIN DECREASED3
HIP FRACTURE3
HYDRONEPHROSIS3
HYPERCALCAEMIA3
HYPERKERATOSIS3
HYPERPARATHYROIDISM3
HYPERTHYROIDISM3
HYPOAESTHESIA ORAL3
HYPOKINESIA3
HYPOVOLAEMIC SHOCK3
IMPAIRED GASTRIC EMPTYING3
IMPAIRED HEALING3
INFLUENZA LIKE ILLNESS3
INTENTIONAL OVERDOSE3
INTESTINAL ISCHAEMIA3
Intestinal malrotation3
IRRITABLE BOWEL SYNDROME3
ISCHAEMIC CEREBRAL INFARCTION3
LACRIMATION INCREASED3
LACUNAR INFARCTION3
LARYNGEAL OEDEMA3
LARYNGOSPASM3
LOW DENSITY LIPOPROTEIN INCREASED3
LUNG CANCER METASTATIC3
LUNG NEOPLASM3
LYMPHOCYTE COUNT DECREASED3
Lymphocyte stimulation test positive3
MACULAR DEGENERATION3
Medication error3
MENTAL IMPAIRMENT3
METASTATIC NEOPLASM3
MOBILITY DECREASED3
MONOCYTE COUNT INCREASED3
MOTOR DYSFUNCTION3
MULTIPLE MYELOMA3
MUSCLE RIGIDITY3
Muscle spasticity3
NEPHROANGIOSCLEROSIS3
NEUTROPENIA3
NOCTURIA3
OBSTRUCTIVE AIRWAYS DISORDER3
OCULAR HYPERAEMIA3
Oesophageal ulcer3
ORCHITIS3
ORGANIC ERECTILE DYSFUNCTION3
OXYGEN SATURATION DECREASED3
PAIN IN JAW3
PAIN OF SKIN3
PARALYSIS3
PARKINSONISM3
PERIPHERAL VASCULAR DISORDER3
Peripheral venous disease3
Persistent cloaca3
PLATELET COUNT INCREASED3
POST PROCEDURAL HAEMORRHAGE3
PRE-ECLAMPSIA3
PRIMARY HYPERALDOSTERONISM3
PROTHROMBIN TIME PROLONGED3
Pseudomembranous colitis3
PSORIASIS3
RAYNAUD'S PHENOMENON3
RECTAL HAEMORRHAGE3
RED BLOOD CELL SEDIMENTATION RATE INCREASED3
RENAL CANCER3
RENAL TUBULAR ACIDOSIS3
RENIN DECREASED3
SENSATION OF PRESSURE3
SENSE OF OPPRESSION3
SENSORY DISTURBANCE3
SERUM FERRITIN INCREASED3
STOMACH DISCOMFORT3
SUBARACHNOID HAEMORRHAGE3
Systemic lupus erythematosus3
THROMBOCYTOSIS3
TONGUE DISCOLOURATION3
TRACHEOBRONCHITIS3
TRANSITIONAL CELL CARCINOMA3
Truncus arteriosus persistent3
ULCER3
UPPER GASTROINTESTINAL HAEMORRHAGE3
Urachal abnormality3
URINE OUTPUT INCREASED3
UROSEPSIS3
VASCULITIS NECROTISING3
Ventricular arrhythmia3
VIRAL INFECTION3
VISUAL FIELD DEFECT3
VITAMIN B12 DEFICIENCY3
VITREOUS DETACHMENT3
VITREOUS HAEMORRHAGE3
YELLOW SKIN3
ABDOMINAL HERNIA2
Abdominal tenderness2
Abdominal wall haemorrhage2
ABNORMAL LOSS OF WEIGHT2
ACARODERMATITIS2
ACCIDENTAL EXPOSURE2
ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED2
ACUTE HEPATIC FAILURE2
ADDUCTOR VOCAL CORD WEAKNESS2
ADENOMA BENIGN2
ALVEOLITIS ALLERGIC2
Amylase increased2
ANAL HAEMORRHAGE2
ANAPHYLACTIC SHOCK2
ANIMAL BITE2
Ankle fracture2
ANOSOGNOSIA2
Aortic dilatation2
APATHY2
APHAGIA2
APHONIA2
Apparent death2
APPENDICITIS2
APPENDICITIS PERFORATED2
Arteriovenous fistula2
Autoimmune thyroiditis2
AUTONOMIC NERVOUS SYSTEM IMBALANCE2
BACK DISORDER2
BACTERAEMIA2
BARRETT'S OESOPHAGUS2
BILIRUBIN CONJUGATED INCREASED2
BILIRUBIN URINE2
BIOPSY KIDNEY2
BLADDER CANCER2
BLADDER DISORDER2
Blood aldosterone decreased2
BLOOD AMYLASE INCREASED2
Blood creatinine decreased2
BLOOD GLUCOSE FLUCTUATION2
BLOOD IRON INCREASED2
BLOOD LACTIC ACID INCREASED2
BLOOD PHOSPHORUS INCREASED2
BLOOD POTASSIUM ABNORMAL2
BLOOD UREA ABNORMAL2
BLOOD UREA NITROGEN/CREATININE RATIO INCREASED2
BODY TEMPERATURE INCREASED2
Bone atrophy2
BRAIN DEATH2
BRAIN INJURY2
BRAIN MASS2
BREAST PAIN2
BRONCHIAL CARCINOMA2
BRONCHIAL HYPERREACTIVITY2
BUNDLE BRANCH BLOCK2
CACHEXIA2
Calcium metabolism disorder2
CANDIDIASIS2
CAPILLARY DISORDER2
CARBON DIOXIDE DECREASED2
CARDIAC DEATH2
CARDIAC MURMUR2
Cardiac output decreased2
Cardiac septal defect2
CARDIAC TAMPONADE2
CARDIAC VALVE DISEASE2
CARDIORENAL SYNDROME2
CARDIOVASCULAR INSUFFICIENCY2
Carotid artery disease2
Carotid artery occlusion2
Carotid artery thrombosis2
CEREBELLAR HAEMORRHAGE2
CEREBRAL ARTERIOSCLEROSIS2
Cerebral hypoperfusion2
CEREBRAL MICROANGIOPATHY2
CHEST X-RAY ABNORMAL2
Cholangitis2
CHOLECYSTITIS ACUTE2
CHOLECYSTITIS INFECTIVE2
Chronic gastritis2
CHRONIC HEPATITIS2
CLAVICLE FRACTURE2
COGNITIVE DISORDER2
COLITIS2
COLITIS ISCHAEMIC2
COLON CANCER METASTATIC2
COLONIC POLYP2
Congenital cardiovascular anomaly2
CONJUNCTIVAL HYPERAEMIA2
CONJUNCTIVITIS2
CORONARY ANGIOPLASTY2
CORONARY ARTERY BYPASS2
CROHN'S DISEASE2
CYST2
CYTOLYTIC HEPATITIS2
Deafness bilateral2
DECREASED ACTIVITY2
Delusion2
Device dislocation2
Diarrhoea infectious2
Disability2
DISTURBANCE IN ATTENTION2
Drug abuse2
DRUG DOSE OMISSION2
DRY EYE2
DUODENAL ULCER2
DYSKINESIA2
DYSSTASIA2
Ear pain2
ECTOPIA CORDIS2
EFFUSION2
Ejection fraction2
ELECTROCARDIOGRAM QRS COMPLEX ABNORMAL2
ELECTROENCEPHALOGRAM ABNORMAL2
Encephalomalacia2
ENCEPHALOPATHY2
EOSINOPHILIC PNEUMONIA2
EPIGASTRIC DISCOMFORT2
ERUCTATION2
EXCORIATION2
Exostosis2
EYE INFECTION2
EYE INJURY2
EYE OEDEMA2
FACIAL PAIN2
FAECES PALE2
Fear2
FOAMING AT MOUTH2
FOOD ALLERGY2
FOREIGN BODY2
FUNGAL INFECTION2
Gait inability2
GALLBLADDER DISORDER2
GANGRENE2
GASTRIC HAEMORRHAGE2
GASTRIC ULCER HAEMORRHAGE2
GASTROINTESTINAL PAIN2
GINGIVAL SWELLING2
GINGIVITIS2
GLOMERULOSCLEROSIS2
GLOSSITIS2
GLYCOSURIA2
GOUTY ARTHRITIS2
GRANULOMA2
GRAVITATIONAL OEDEMA2
GUTTATE PSORIASIS2
HAEMODIALYSIS2
Haemodynamic instability2
HAEMORRHAGIC DIATHESIS2
Helicobacter infection2
HEMIANOPIA HOMONYMOUS2
HEPATIC NEOPLASM2
HEPATITIS A2
HEPATITIS ACUTE2
HEPATITIS CHOLESTATIC2
HIP SURGERY2
HYPERCREATININAEMIA2
HYPERMAGNESAEMIA2
HYPERPHOSPHATAEMIA2
Hypersensitivity vasculitis2
HYPERTENSIVE ENCEPHALOPATHY2
HYPERTONIA2
Hypoacusis2
HYPOAESTHESIA FACIAL2
HYPOALBUMINAEMIA2
Hypogonadism2
Hypomagnesaemia2
HYPOPROTEINAEMIA2
Hypoxic-ischaemic encephalopathy2
IDIOPATHIC THROMBOCYTOPENIC PURPURA2
ILEUS2
Ill-defined disorder2
Immune thrombocytopenic purpura2
Immunodeficiency2
INCONTINENCE2
INCREASED UPPER AIRWAY SECRETION2
Infected skin ulcer2
INGUINAL HERNIA2
INTERNATIONAL NORMALISED RATIO DECREASED2
Intracranial pressure increased2
ISCHAEMIA2
JAW DISORDER2
KNEE ARTHROPLASTY2
LICHEN PLANUS2
LICHENOID KERATOSIS2
LIFE SUPPORT2
Limb deformity2
Limb malformation2
LIP DRY2
Liver abscess2
LIVER INJURY2
LOCALISED INFECTION2
LOWER LIMB FRACTURE2
LUNG SQUAMOUS CELL CARCINOMA STAGE III2
Macular fibrosis2
Macular oedema2
MALIGNANT PLEURAL EFFUSION2
MEAN CELL HAEMOGLOBIN CONCENTRATION DECREASED2
MEAN CELL VOLUME DECREASED2
MECHANICAL VENTILATION2
MEDIASTINAL DISORDER2
MEDICATION RESIDUE2
MENORRHAGIA2
METABOLIC DISORDER2
Metabolic encephalopathy2
Metastases to bone marrow2
METASTASIS2
MICROCYTIC ANAEMIA2
MICTURITION DISORDER2
MICTURITION URGENCY2
MIGRAINE2
MONOCLONAL GAMMOPATHY2
MOUTH ULCERATION2
MUCOSAL DRYNESS2
MUCOUS STOOLS2
Multiple organ dysfunction syndrome2
MUMPS2
MUSCLE STRAIN2
MUSCLE TWITCHING2
Musculoskeletal disorder2
MYOCLONIC EPILEPSY2
NEPHRITIS2
NERVE INJURY2
NERVOUS SYSTEM DISORDER2
NO ADVERSE EVENT2
NO THERAPEUTIC RESPONSE2
Nodal rhythm2
NOREPINEPHRINE INCREASED2
NORMAL NEWBORN2
OESOPHAGEAL PAIN2
OESOPHAGITIS2
Off label use2
OPTIC ISCHAEMIC NEUROPATHY2
ORAL DISORDER2
Oral mucosal blistering2
OROPHARYNGEAL SWELLING2
Osteopenia2
PALATAL OEDEMA2
PANCREATIC CARCINOMA2
Pancreatic insufficiency2
PANCREATIC PSEUDOCYST2
PANIC ATTACK2
PANIC DISORDER2
PARTIAL SEIZURES2
Pelvic fracture2
PERICARDITIS2
PERIPHERAL ISCHAEMIA2
Peritonitis2
PERIVASCULAR DERMATITIS2
PERSONALITY DISORDER2
PHARYNGEAL DISORDER2
PHARYNGOLARYNGEAL PAIN2
PHLEBITIS2
Pituitary tumour benign2
POLYCYTHAEMIA2
POLYDIPSIA2
POLYP2
PORTAL VEIN THROMBOSIS2
PRODUCT PHYSICAL ISSUE2
Product quality issue2
Product use in unapproved indication2
PROSTATIC DISORDER2
PROSTATIC SPECIFIC ANTIGEN INCREASED2
PROSTATOMEGALY2
PROTEIN TOTAL INCREASED2
PSEUDOMONAS INFECTION2
PSYCHIATRIC SYMPTOM2
PSYCHOMOTOR RETARDATION2
Pyelonephritis acute2
Pyuria2
RASH VESICULAR2
Rebound effect2
REFLEXES ABNORMAL2
RENAL MASS2
RENAL TUBULAR DISORDER2
Retching2
Retinal haemorrhage2
RETINAL TEAR2
RETINOPATHY2
Rhinitis2
RHINITIS ALLERGIC2
RHINORRHOEA2
Rotator cuff syndrome2
Scar2
SCHIZOPHRENIA2
SEROTONIN SYNDROME2
Serum ferritin decreased2
SEXUAL DYSFUNCTION2
SINUS DISORDER2
Sinus node dysfunction2
SJOGREN'S SYNDROME2
Skin cancer2
SKIN FISSURES2
SKIN HAEMORRHAGE2
SKIN HYPERPIGMENTATION2
SKIN NECROSIS2
SKIN REACTION2
SLUGGISHNESS2
SPINAL COLUMN STENOSIS2
Spinal disorder2
STAPHYLOCOCCUS TEST POSITIVE2
Streptococcal infection2
SUBCUTANEOUS ABSCESS2
SUBDURAL HAEMATOMA2
SUFFOCATION FEELING2
SUPRAVENTRICULAR EXTRASYSTOLES2
SYNOVIAL CYST2
TENSION2
THALAMUS HAEMORRHAGE2
THROAT CANCER2
THROMBOPHLEBITIS2
Thyroid neoplasm2
TONGUE HAEMORRHAGE2
TONIC CLONIC MOVEMENTS2
TONSILLITIS2
TOOTH FRACTURE2
TOOTHACHE2
TOXIC EPIDERMAL NECROLYSIS2
TRANSFUSION2
TUBULOINTERSTITIAL NEPHRITIS2
TUMOUR EXCISION2
Upper respiratory tract inflammation2
URAEMIC ENCEPHALOPATHY2
URINE ABNORMALITY2
URINE PROTEIN/CREATININE RATIO INCREASED2
Vaginal haemorrhage2
VARICOSE VEIN2
VASCULAR PURPURA2
Vasodilatation2
VENOUS INSUFFICIENCY2
Ventricular dysfunction2
VERTIGO POSITIONAL2
Vitamin D deficiency2
VITREOUS FLOATERS2
WITHDRAWAL HYPERTENSION2
WOUND2
ABDOMINAL MASS1
Abdominal sepsis1
ABNORMAL DREAMS1
ABNORMAL SENSATION IN EYE1
ACCIDENT1
Accident at work1
Accidental exposure to product1
ACNE1
Acquired epidermolysis bullosa1
Actinic keratosis1
ACUTE FEBRILE NEUTROPHILIC DERMATOSIS1
ACUTE MYELOID LEUKAEMIA1
Acute right ventricular failure1
ACUTE STRESS DISORDER1
ADENOCARCINOMA1
Adenocarcinoma gastric1
Adjustment disorder1
Adrenal gland cancer1
ADRENAL NEOPLASM1
Affect lability1
AFFECTIVE DISORDER1
Age-related macular degeneration1
AGEUSIA1
Alcoholic liver disease1
ALKALOSIS1
ALLERGIC HEPATITIS1
ALLERGY TO CHEMICALS1
ALOPECIA AREATA1
AMAUROSIS FUGAX1
ANAEMIA MACROCYTIC1
Anaemia of chronic disease1
Anaemia of malignant disease1
ANAEMIA VITAMIN B12 DEFICIENCY1
ANAL EROSION1
ANAL PRURITUS1
ANASTOMOTIC ULCER1
ANGER1
Angiodermatitis1
ANGIOPATHY1
ANGIOSCLEROSIS1
ANGLE CLOSURE GLAUCOMA1
ANIMAL SCRATCH1
ANION GAP DECREASED1
ANORECTAL DISCOMFORT1
ANOREXIA1
ANOSMIA1
Anticoagulation drug level above therapeutic1
ANTICONVULSANT DRUG LEVEL BELOW THERAPEUTIC1
ANTINEUTROPHIL CYTOPLASMIC ANTIBODY1
ANTIPSYCHOTIC DRUG LEVEL INCREASED1
AORTIC CALCIFICATION1
Aortic injury1
Aortic valve stenosis1
Aplastic anaemia1
APNOEA1
APPARENT LIFE THREATENING EVENT1
APPENDICECTOMY1
ARTERIAL STENOSIS1
ASPIRATION PLEURAL CAVITY1
Asthenopia1
ASTHMATIC CRISIS1
ASTIGMATISM1
Ataxia1
ATRIAL TACHYCARDIA1
ATRIOVENTRICULAR DISSOCIATION1
ATRIOVENTRICULAR EXTRASYSTOLES1
AURA1
AUTOIMMUNE DISORDER1
Autoimmune haemolytic anaemia1
Autoimmune hepatitis1
AUTOIMMUNE THROMBOCYTOPENIA1
BACTERIA BLOOD IDENTIFIED1
Bacterial sepsis1
BACTERIAL TEST POSITIVE1
BASAL CELL CARCINOMA1
BASAL GANGLIA HAEMORRHAGE1
Basal ganglia stroke1
BASILAR ARTERY OCCLUSION1
BASOPHIL COUNT DECREASED1
BED REST1
BEDRIDDEN1
Benign mediastinal neoplasm1
BENIGN NEOPLASM1
Benign prostatic hyperplasia1
BIFASCICULAR BLOCK1
BIOPSY BONE MARROW ABNORMAL1
BIOPSY BREAST1
BIOPSY KIDNEY ABNORMAL1
BIOPSY LIVER1
BIOPSY SITE UNSPECIFIED ABNORMAL1
Bladder outlet obstruction1
Bladder transitional cell carcinoma1
Blast cell count increased1
BLOOD ALCOHOL INCREASED1
BLOOD BICARBONATE INCREASED1
BLOOD CHLORIDE DECREASED1
BLOOD COUNT ABNORMAL1
BLOOD CREATINE PHOSPHOKINASE MB INCREASED1
BLOOD ELECTROLYTES INCREASED1
BLOOD ERYTHROPOIETIN INCREASED1
BLOOD FIBRINOGEN INCREASED1
Blood homocysteine increased1
BLOOD MAGNESIUM ABNORMAL1
BLOOD MAGNESIUM DECREASED1
BLOOD OSMOLARITY DECREASED1
BLOOD PARATHYROID HORMONE INCREASED1
BLOOD PH INCREASED1
Blood pressure orthostatic1
BLOOD PROLACTIN INCREASED1
BLOOD THYROID STIMULATING HORMONE INCREASED1
BLOOD URINE1
BLOODY DISCHARGE1
Bone disorder1
Bone graft1
BONE MARROW DISORDER1
BONE NEOPLASM1
BORRELIA INFECTION1
Bowel movement irregularity1
BRADYKINESIA1
BRAIN NEOPLASM1
Brain stem haemorrhage1
BRAIN STEM STROKE1
Breast cancer metastatic1
BREATH ODOUR1
BRONCHIAL IRRITATION1
BRONCHIAL OBSTRUCTION1
BRONCHIOLITIS1
BRONCHITIS BACTERIAL1
BRONCHOALVEOLAR LAVAGE ABNORMAL1
BRONCHOPNEUMOPATHY1
CAESAREAN SECTION1
Calculus urinary1
CAMPYLOBACTER GASTROENTERITIS1
Carbohydrate antigen 125 increased1
CARBON MONOXIDE POISONING1
CARCINOID TUMOUR OF THE DUODENUM1
CARDIAC ASTHMA1
Cardiac sarcoidosis1
Cardiac valve rupture1
CARDIAC VENTRICULAR DISORDER1
CARDIOVERSION1
Carotid arteriosclerosis1
CAROTID PULSE1
CASTLEMAN'S DISEASE1
Cataract nuclear1
CATARACT OPERATION1
CATHETER PLACEMENT1
CATHETER REMOVAL1
Catheter site infection1
CAUTERY TO NOSE1
CELL DEATH1
Cellulitis staphylococcal1
CENTRAL NERVOUS SYSTEM INFECTION1
CENTRAL NERVOUS SYSTEM LESION1
CEREBELLAR HAEMANGIOMA1
CEREBELLAR SYNDROME1
CEREBRAL ARTERY EMBOLISM1
CEREBRAL ARTERY STENOSIS1
CEREBRAL DISORDER1
CEREBRAL HAEMATOMA1
Cerebral vasoconstriction1
CEREBROVASCULAR STENOSIS1
Cervical spinal stenosis1
Cervicitis1
Chest injury1
CHEYNE-STOKES RESPIRATION1
CHOKING SENSATION1
CHOLECYSTECTOMY1
CHOLURIA1
CHRONIC RESPIRATORY FAILURE1
Chronic sinusitis1
CIRCUMORAL OEDEMA1
CLONIC CONVULSION1
Clumsiness1
Coagulation time prolonged1
COELIAC DISEASE1
COLECTOMY1
COLITIS COLLAGENOUS1
COLORECTAL CANCER1
COMA SCALE ABNORMAL1
COMPLETED SUICIDE1
CONDUCTION DISORDER1
CONGENITAL CENTRAL NERVOUS SYSTEM ANOMALY1
CONGENITAL CYSTIC KIDNEY DISEASE1
CONTINUOUS HAEMODIAFILTRATION1
Conversion disorder1
CORONARY ARTERY DILATATION1
Coronary artery embolism1
CORONARY ARTERY THROMBOSIS1
Cortical laminar necrosis1
CORTISOL FREE URINE INCREASED1
Costovertebral angle tenderness1
CRANIOCEREBRAL INJURY1
CREATININE RENAL CLEARANCE1
Creatinine renal clearance abnormal1
CREATININE RENAL CLEARANCE INCREASED1
CREATININE URINE DECREASED1
CREUTZFELDT-JAKOB DISEASE1
CRYING1
CSF SHUNT REMOVAL1
Cushingoid1
CYSTITIS HAEMORRHAGIC1
CYTOMEGALOVIRUS TEST POSITIVE1
Deafness1
Defect conduction intraventricular1
DELUSIONAL PERCEPTION1
Dementia of the Alzheimer's type, with delirium1
DEMYELINATING POLYNEUROPATHY1
Dental caries1
DERMATITIS PSORIASIFORM1
DERMATOSIS1
Device malfunction1
Diabetic autonomic neuropathy1
Diabetic complication1
DIABETIC FOOT1
DIABETIC GASTROPARESIS1
DIABETIC KETOACIDOSIS1
Diabetic retinal oedema1
Dialysis disequilibrium syndrome1
Diaphragmatic hernia1
DIARRHOEA HAEMORRHAGIC1
DIVERTICULAR PERFORATION1
DIVERTICULITIS1
DIZZINESS POSTURAL1
Drug administration error1
Drug dependence1
Drug reaction with eosinophilia and systemic symptoms1
DRUG RESISTANCE1
DRUG TOXICITY1
DRY THROAT1
DUODENAL NEOPLASM1
Duodenal polyp1
Duodenitis1
DYSAESTHESIA1
DYSLALIA1
Dysmenorrhoea1
DYSPHORIA1
Ear disorder1
Ear pruritus1
Early satiety1
ECCHYMOSIS1
ECHOCARDIOGRAM1
ECHOCARDIOGRAM ABNORMAL1
ECHOGRAPHY ABNORMAL1
ECZEMA VESICULAR1
EJACULATION DISORDER1
Ejection fraction abnormal1
Electrocardiogram Q waves1
ELECTROCARDIOGRAM QRS COMPLEX SHORTENED1
ELECTROCARDIOGRAM QT SHORTENED1
ELECTROCARDIOGRAM ST SEGMENT DEPRESSION1
ELECTROCARDIOGRAM ST SEGMENT ELEVATION1
ELECTROCARDIOGRAM T WAVE AMPLITUDE INCREASED1
Electrocardiogram T wave inversion1
EMBOLISM1
Embolism venous1
EMOTIONAL DISTRESS1
End stage renal disease1
Endocarditis staphylococcal1
Endocrine disorder1
ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY1
ENTERITIS1
Enteritis infectious1
Enterocolitis1
ENZYME ABNORMALITY1
ENZYME ACTIVITY DECREASED1
EOSINOPHIL COUNT DECREASED1
EOSINOPHIL PERCENTAGE INCREASED1
Eosinophilic cellulitis1
EOSINOPHILIC OESOPHAGITIS1
Epidermal necrosis1
EPINEPHRINE INCREASED1
EPSTEIN-BARR VIRUS INFECTION1
EROSIVE DUODENITIS1
ERYTHEMA NODOSUM1
ERYTHEMA OF EYELID1
Essential hypertension1
ESSENTIAL TREMOR1
Exercise tolerance decreased1
Expired product administered1
Extradural haematoma1
EXTRANODAL MARGINAL ZONE B-CELL LYMPHOMA (MALT TYPE)1
EXTRAPYRAMIDAL DISORDER1
EXTRASKELETAL OSSIFICATION1
EXTUBATION1
EYE IRRITATION1
EYE MOVEMENT DISORDER1
Eye pruritus1
EYELIDS PRURITUS1
FACIAL PARESIS1
Faecal elastase concentration decreased1
Failure to thrive1
FEAR OF DEATH1
Feeling jittery1
Feeling of despair1
FEMORAL ARTERY OCCLUSION1
FIBRIN D DIMER INCREASED1
Fibrocystic breast disease1
FIBROSIS1
FILARIASIS1
FISTULA1
FLUID INTAKE REDUCED1
FLUID REPLACEMENT1
Foetal growth restriction1
FOETAL HEART RATE ABNORMAL1
FOETAL MALFORMATION1
FOOD INTOLERANCE1
FOOT DEFORMITY1
Foot fracture1
FORMICATION1
Frequent bowel movements1
FULL BLOOD COUNT DECREASED1
FURUNCLE1
GALACTORRHOEA1
Gallbladder enlargement1
GALLBLADDER OPERATION1
GALLBLADDER PAIN1
GAMMA-GLUTAMYLTRANSFERASE1
GAMMA-GLUTAMYLTRANSFERASE ABNORMAL1
GASTRECTOMY1
Gastric adenoma1
Gastric fistula1
Gastric mucosal lesion1
Gastric neoplasm1
Gastric perforation1
Gastric polyps1
Gastritis viral1
GASTROENTERITIS CLOSTRIDIAL1
Gastrointestinal angiodysplasia1
GASTROINTESTINAL CARCINOMA1
Gastrointestinal infection1
GASTROINTESTINAL NEOPLASM1
GASTROINTESTINAL SOUNDS ABNORMAL1
GASTROINTESTINAL STROMAL TUMOUR1
GASTROSTOMY TUBE INSERTION1
Genital cancer male1
GINGIVAL ABSCESS1
GINGIVAL BLEEDING1
GINGIVAL DISORDER1
GINGIVAL ERYTHEMA1
Gingival hyperplasia1
Gingival hypertrophy1
Gingival pain1
GLIOSIS1
Glomerular filtration rate abnormal1
GLOMERULAR VASCULAR DISORDER1
GLOMERULONEPHRITIS MEMBRANOUS1
GLOMERULONEPHRITIS RAPIDLY PROGRESSIVE1
GLUCOSE TOLERANCE IMPAIRED1
GLUCOSE TOLERANCE TEST ABNORMAL1
GRANULOCYTE COUNT DECREASED1
Grunting1
Haemangioma of liver1
Haemarthrosis1
HAEMOCHROMATOSIS1
HAEMOGLOBIN ABNORMAL1
Haemolysis1
HAEMOLYTIC URAEMIC SYNDROME1
HAEMOPTYSIS1
HAEMORRHAGE URINARY TRACT1
HAEMORRHAGIC ANAEMIA1
HAEMORRHAGIC DISORDER1
Haemorrhagic infarction1
HAEMORRHAGIC URTICARIA1
Haemorrhagic vasculitis1
HAEMOTHORAX1
HAIR COLOUR CHANGES1
HALLUCINATION, AUDITORY1
HANTAVIRAL INFECTION1
HEART SOUNDS ABNORMAL1
HEART TRANSPLANT1
Heart valve incompetence1
HEART VALVE REPLACEMENT1
HEMIANOPIA1
HEPATIC EMBOLISATION1
HEPATIC ENZYME ABNORMAL1
HEPATIC FIBROSIS1
HEPATIC LESION1
HEPATITIS B ANTIBODY POSITIVE1
Hepatocellular carcinoma1
HERNIA REPAIR1
HERPES SIMPLEX1
Hiccups1
HIGH DENSITY LIPOPROTEIN INCREASED1
HIGH FREQUENCY ABLATION1
Hip arthroplasty1
HISTAMINE LEVEL INCREASED1
HISTIOCYTOSIS1
HISTOLOGY ABNORMAL1
HOMICIDAL IDEATION1
Homocystinaemia1
HOSPITALISATION1
HUMERUS FRACTURE1
HYDROCELE1
Hydrocephalus1
Hyperadrenalism1
HYPERAEMIA1
HYPERALBUMINAEMIA1
HYPERALDOSTERONISM1
HYPERCHLORHYDRIA1
HYPERCREATINAEMIA1
Hyperglycaemic hyperosmolar nonketotic syndrome1
HYPERKINESIA1
HYPERLIPASAEMIA1
HYPERPROTEINAEMIA1
HYPERSOMNIA1
HYPERTENSIVE CARDIOMYOPATHY1
Hypertensive emergency1
HYPERTENSIVE HEART DISEASE1
Hypertensive nephropathy1
Hyperthermia1
Hypertransaminasaemia1
HYPERTROPHIC CARDIOMYOPATHY1
HYPERTROPHY1
HYPERURICOSURIA1
Hypochromic anaemia1
HYPOGLYCAEMIC COMA1
Hypoosmolar state1
Hypoparathyroidism1
HYPOPERFUSION1
Hyporeflexia1
HYPOTHERMIA1
HYPOVENTILATION1
ICHTHYOSIS1
Idiopathic urticaria1
IDIOSYNCRATIC DRUG REACTION1
ILLUSION1
IMPAIRED DRIVING ABILITY1
IMPAIRED WORK ABILITY1
IMPLANTABLE DEFIBRILLATOR INSERTION1
IN-STENT CORONARY ARTERY RESTENOSIS1
INCISIONAL DRAINAGE1
Incorrect drug dosage form administered1
INFECTION PARASITIC1
INFECTIOUS DISEASE CARRIER1
INFECTIOUS PERITONITIS1
INFECTIOUS PLEURAL EFFUSION1
Inferior vena cava dilatation1
Inflammatory bowel disease1
INTERMITTENT CLAUDICATION1
INTESTINAL GANGRENE1
INTESTINAL OBSTRUCTION1
INTESTINAL RESECTION1
INTRACARDIAC THROMBUS1
INTRACRANIAL HYPOTENSION1
INTRAVENTRICULAR HAEMORRHAGE1
INTUBATION1
Ischaemic hepatitis1
ITCHING SCAR1
Joint dislocation1
JOINT EFFUSION1
Joint injury1
JOINT STIFFNESS1
JUGULAR VEIN DISTENSION1
KETOSIS1
KIDNEY ENLARGEMENT1
KIDNEY FIBROSIS1
KIDNEY SMALL1
Klebsiella infection1
KNEE OPERATION1
Labelled drug-drug interaction medication error1
LABILE HYPERTENSION1
LACTOSE INTOLERANCE1
LEUKOCYTURIA1
Leukoplakia1
LIBIDO DECREASED1
Lichen sclerosus1
LIGAMENT SPRAIN1
Limb injury1
LIMB TRAUMATIC AMPUTATION1
LIP AND/OR ORAL CAVITY CANCER1
LIP EROSION1
LIP EXFOLIATION1
LIPID METABOLISM DISORDER1
LIPIDS ABNORMAL1
Liver tenderness1
LOCALISED OEDEMA1
LOCHIAL INFECTION1
LOGORRHOEA1
Long QT syndrome1
LOSS OF LIBIDO1
Low birth weight baby1
LOWER RESPIRATORY TRACT INFECTION1
LUMBAR SPINAL STENOSIS1
LUNG CARCINOMA CELL TYPE UNSPECIFIED RECURRENT1
LYMPHADENECTOMY1
LYMPHADENOPATHY MEDIASTINAL1
LYMPHOCELE1
LYMPHOCYTE PERCENTAGE DECREASED1
LYMPHOPENIA1
MACROANGIOPATHY1
MACROGLOSSIA1
MAJOR DEPRESSION1
Malignant glioma1
Malignant neoplasm progression1
Malignant urinary tract neoplasm1
Mallory-Weiss syndrome1
MALNUTRITION1
MASS1
MASTITIS1
MATERNAL DRUGS AFFECTING FOETUS1
MEAN CELL HAEMOGLOBIN DECREASED1
MEAN CELL VOLUME INCREASED1
MEAN PLATELET VOLUME DECREASED1
Medical device complication1
Medication residue present1
MENISCAL DEGENERATION1
Meniscus injury1
MENOPAUSE1
Menstrual disorder1
MESENTERIC ARTERY EMBOLISM1
MESENTERIC ARTERY STENOSIS1
METABOLIC SYNDROME1
METAMYELOCYTE COUNT INCREASED1
Metastases to bone1
METASTASES TO KIDNEY1
MICROANGIOPATHY1
MIDDLE INSOMNIA1
Migraine without aura1
Mineral deficiency1
MITRAL VALVE CALCIFICATION1
MIXED LIVER INJURY1
MONOCYTE COUNT DECREASED1
MONOCYTE PERCENTAGE INCREASED1
MONOCYTOSIS1
Mood altered1
MORBID THOUGHTS1
MOUNTAIN SICKNESS ACUTE1
MOUTH HAEMORRHAGE1
MOUTH INJURY1
MUCOSAL EROSION1
MUCOSAL HAEMORRHAGE1
Mucosal inflammation1
MUCOSAL ULCERATION1
MUCOUS MEMBRANE DISORDER1
MULTIPLE FRACTURES1
MUSCLE ATROPHY1
MUSCLE DISORDER1
MUSCLE INJURY1
MUSCULOSKELETAL CHEST PAIN1
Musculoskeletal discomfort1
MUTISM1
Myasthenia gravis1
MYELODYSPLASTIC SYNDROME TRANSFORMATION1
Myelopathy1
Myocarditis1
MYOCLONUS1
MYOGLOBIN BLOOD INCREASED1
MYOPATHY1
N-TERMINAL PROHORMONE BRAIN NATRIURETIC PEPTIDE1
N-terminal prohormone brain natriuretic peptide increased1
Nasal septum deviation1
Neck dissection1
Neck injury1
NECROSIS ISCHAEMIC1
NECROSIS OF ARTERY1
NEGATIVE THOUGHTS1
Neonatal respiratory distress syndrome1
NEOPLASM1
NEOPLASM RECURRENCE1
NEPHRITIC SYNDROME1
NEPHROPATHY TOXIC1
NEURITIS1
NEURODERMATITIS1
Neurofibroma1
Neurologic neglect syndrome1
NEUROLOGICAL DECOMPENSATION1
NEUROLOGICAL SYMPTOM1
Neurosis1
NEUTROPHIL PERCENTAGE INCREASED1
NIGHT BLINDNESS1
NIPPLE PAIN1
NODAL ARRHYTHMIA1
NUCLEAR MAGNETIC RESONANCE IMAGING BRAIN ABNORMAL1
Nutritional condition abnormal1
NYSTAGMUS1
OBSTRUCTION1
Obstructive uropathy1
Occult blood positive1
OCULAR VASCULAR DISORDER1
OEDEMA MUCOSAL1
Oesophageal carcinoma1
Oesophageal disorder1
OESOPHAGEAL VARICES HAEMORRHAGE1
OESOPHAGOGASTROSTOMY1
Onychomycosis1
Open angle glaucoma1
OPTIC NEURITIS1
ORAL CANDIDIASIS1
ORAL LICHEN PLANUS1
ORAL MUCOSA EROSION1
ORAL PAIN1
ORBITAL OEDEMA1
OROPHARYNGEAL DISCOMFORT1
ORTHOSTATIC INTOLERANCE1
OSTEONECROSIS1
Otorrhoea1
Ovarian cancer1
OXYGEN CONSUMPTION DECREASED1
PANCREAS LIPOMATOSIS1
PANCREATIC CALCIFICATION1
Pancreatic duct obstruction1
PANCREATIC ENZYMES INCREASED1
PANCREATIC MASS1
Pancreatitis chronic1
PANCREATITIS HAEMORRHAGIC1
PANCREATITIS RELAPSING1
Papule1
PARADOXICAL DRUG REACTION1
PARADOXICAL PRESSOR RESPONSE1
Parakeratosis1
PARENTERAL NUTRITION1
PARESIS1
Patella fracture1
Pelvic discomfort1
Pelvic fluid collection1
PELVIC MASS1
PEMPHIGUS1
PENILE OEDEMA1
PENIS DISORDER1
Peptic ulcer1
Peptic ulcer perforation1
PERCUTANEOUS CORONARY INTERVENTION1
Performance status decreased1
Periarthritis1
PERICARDIAL EXCISION1
PERICARDIAL HAEMORRHAGE1
PERIORBITAL DISORDER1
Periorbital swelling1
PERIPHERAL EMBOLISM1
Peritoneal cloudy effluent1
PERITONEAL PERMEABILITY INCREASED1
PERONEAL NERVE PALSY1
PERSONALITY CHANGE1
Phantom pain1
Pharyngeal cancer1
PHARYNGITIS1
PHOTOPHOBIA1
PHYSICAL DISABILITY1
Pituitary enlargement1
Plantar fasciitis1
Plasma cell myeloma1
PLASMACYTOMA1
PLATELET AGGREGATION1
PLEURAL ADHESION1
Pleural fibrosis1
PNEUMONIA BACTERIAL1
PNEUMONIA FUNGAL1
PNEUMONIA MYCOPLASMAL1
PNEUMONIA PNEUMOCOCCAL1
PNEUMOTHORAX1
PO2 DECREASED1
Poisoning1
POLYARTHRITIS1
Polyglandular autoimmune syndrome type III1
POLYMENORRHOEA1
Poor quality product administered1
Poor quality sleep1
POROKERATOSIS1
Portal hypertensive gastropathy1
Post procedural complication1
POST PROCEDURAL INFECTION1
POST-TRAUMATIC PAIN1
Post-traumatic stress disorder1
Postoperative wound complication1
POSTOPERATIVE WOUND INFECTION1
Postrenal failure1
PRE-EXISTING CONDITION IMPROVED1
PREGNANCY1
Premature baby1
Premature delivery1
PRIAPISM1
Proctalgia1
Product dose omission1
Product monitoring error1
Product storage error1
Product taste abnormal1
PROSTATE TENDERNESS1
PROSTATECTOMY1
PROSTATIC ADENOMA1
Prostatic obstruction1
PROSTATIC OPERATION1
Prostatitis1
PROSTHESIS IMPLANTATION1
Protein total abnormal1
PROTEIN URINE1
PROTHROMBIN TIME SHORTENED1
PRURITUS ALLERGIC1
Psychomotor skills impaired1
PSYCHOSOMATIC DISEASE1
PSYCHOTIC DISORDER1
PSYCHOTIC DISORDER DUE TO A GENERAL MEDICAL CONDITION1
Pubis fracture1
PULMONARY ARTERIAL HYPERTENSION1
PULMONARY ARTERIAL WEDGE PRESSURE DECREASED1
Pulmonary function test abnormal1
PULMONARY HAEMORRHAGE1
Pulmonary mass1
PULMONARY THROMBOSIS1
PURULENCE1
PUSTULAR PSORIASIS1
QRS axis abnormal1
QUADRIPARESIS1
QUALITY OF LIFE DECREASED1
RADIATION INJURY1
RADIATION SICKNESS SYNDROME1
RADICULOPATHY1
RADIOTHERAPY1
REACTION TO DRUG EXCIPIENTS1
Rectal adenoma1
RECTAL CANCER METASTATIC1
RECTAL POLYP1
RED BLOOD CELLS URINE1
RED CELL DISTRIBUTION WIDTH INCREASED1
REFRACTORY ANAEMIA1
Refractory cytopenia with unilineage dysplasia1
RENAL ANEURYSM1
RENAL ARTERIOSCLEROSIS1
Renal artery occlusion1
RENAL ARTERY THROMBOSIS1
RENAL COLIC1
RENAL INJURY1
RENAL ISCHAEMIA1
RENAL NEOPLASM1
RENAL TUBULAR ATROPHY1
RENAL VESSEL DISORDER1
Respiratory alkalosis1
Respiratory tract congestion1
RETICULOCYTE COUNT INCREASED1
Retinal artery embolism1
Retinal artery occlusion1
Retinal detachment1
Retinal vein occlusion1
RETINOPATHY HYPERTENSIVE1
RETROGRADE AMNESIA1
Retrograde ejaculation1
Retroperitoneal fibrosis1
RHINOVIRUS INFECTION1
RHONCHI1
RHYTHM IDIOVENTRICULAR1
RIB DEFORMITY1
SALIVARY HYPERSECRETION1
SCIATICA1
Scleroderma1
SCREAMING1
SEASONAL ALLERGY1
SEBORRHOEIC KERATOSIS1
Secondary hypertension1
SEDATION1
Senile ankylosing vertebral hyperostosis1
SENSATION OF FOREIGN BODY1
SEROMA1
SEROSITIS1
Shock hypoglycaemic1
SHORT-BOWEL SYNDROME1
Sialoadenitis1
SICK SINUS SYNDROME1
SILENT MYOCARDIAL INFARCTION1
Single functional kidney1
Sinoatrial block1
SINUS ARREST1
SKELETAL INJURY1
SKIN BURNING SENSATION1
SKIN INFECTION1
SKIN INJURY1
SKIN IRRITATION1
SKIN OPERATION1
Skin papilloma1
Skin plaque1
SKIN SWELLING1
SKIN TEST NEGATIVE1
SKIN TIGHTNESS1
SLOW SPEECH1
Small cell lung cancer1
SMALL CELL LUNG CANCER STAGE UNSPECIFIED1
Small intestinal haemorrhage1
SOCIAL PHOBIA1
Soft tissue infection1
SOMNAMBULISM1
SOPOR1
Spinal compression fracture1
SPINAL CORD COMPRESSION1
SPINAL CORD INJURY CERVICAL1
Spinal fracture1
SPINAL MYELOGRAM ABNORMAL1
Spinal pain1
SPLENIC EMBOLISM1
SQUAMOUS CELL CARCINOMA1
Squamous cell carcinoma of lung1
Staphylococcal sepsis1
Stasis dermatitis1
STATUS EPILEPTICUS1
Steatorrhoea1
STENT OCCLUSION1
STOMA CARE1
Streptobacillus test positive1
STREPTOCOCCAL SEPSIS1
Suicide attempt1
SYNOVIAL RUPTURE1
SYSTEMIC INFLAMMATORY RESPONSE SYNDROME1
SYSTOLIC HYPERTENSION1
TELANGIECTASIA1
TENSION HEADACHE1
THALAMIC INFARCTION1
THALASSAEMIA1
THERAPEUTIC AGENT TOXICITY1
THERAPEUTIC PRODUCT INEFFECTIVE1
THERAPEUTIC RESPONSE UNEXPECTED1
Therapy cessation1
THERMAL BURN1
THORACIC CAVITY DRAINAGE1
Thoracic vertebral fracture1
THROMBOTIC STROKE1
THROMBOTIC THROMBOCYTOPENIC PURPURA1
THYROID HAEMORRHAGE1
THYROID OPERATION1
THYROIDECTOMY1
Thyrotoxic crisis1
TONGUE COATED1
TONGUE HAEMATOMA1
TONGUE INJURY1
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED1
Tongue paralysis1
TONSILLAR INFLAMMATION1
TOOTH EXTRACTION1
Total lung capacity decreased1
Toxic encephalopathy1
Tracheal disorder1
Transferrin increased1
TRANSFERRIN SATURATION INCREASED1
TRANSPLANT REJECTION1
TRANSURETHRAL PROSTATECTOMY1
TREATMENT FAILURE1
TRICHORRHEXIS1
TRIGEMINAL NEURALGIA1
TRISOMY 131
TRISOMY 181
TROPONIN I INCREASED1
TRYPTASE1
TYPE 1 DIABETES MELLITUS1
TYPE I HYPERSENSITIVITY1
ULTRASOUND CHEST1
ULTRASOUND KIDNEY ABNORMAL1
ULTRASOUND SCAN ABNORMAL1
Umbilical hernia1
UNRESPONSIVE TO STIMULI1
Upper-airway cough syndrome1
URETERAL DIVERTICULUM1
URETHRAL DISCHARGE1
URETHRAL INJURY1
URETHRITIS1
URETHROSCOPY1
URINARY CASTS1
Urinary retention postoperative1
URINARY TRACT DISORDER1
URINARY TRACT INFLAMMATION1
Urine albumin/creatinine ratio decreased1
Urine analysis abnormal1
URINE ODOUR ABNORMAL1
UTERINE CONTRACTIONS DURING PREGNANCY1
UTERINE LEIOMYOMA1
Uveitis1
VAGINAL DISCHARGE1
VARICELLA VIRUS TEST POSITIVE1
VARICOSE VEIN RUPTURED1
Vascular calcification1
Vascular dementia1
Vascular encephalopathy1
Vascular graft occlusion1
Vascular occlusion1
VASOPLEGIA SYNDROME1
Vein rupture1
VENOUS PRESSURE INCREASED1
Venous pressure jugular increased1
Venous stenosis1
VENOUS THROMBOSIS1
VENOUS THROMBOSIS LIMB1
Ventricular dyskinesia1
VENTRICULAR FAILURE1
VENTRICULAR PRE-EXCITATION1
Ventricular tachyarrhythmia1
VERTEBRAL ARTERY STENOSIS1
Vertebrobasilar insufficiency1
VESTIBULAR NEURONITIS1
VITAL CAPACITY DECREASED1
Volume blood increased1
VULVOVAGINAL MYCOTIC INFECTION1
Walking disability1
WEGENER'S GRANULOMATOSIS1
WHITE BLOOD CELL DISORDER1
WHITE BLOOD CELLS URINE POSITIVE1
WITHDRAWAL SYNDROME1
WOUND INFECTION1
Wound infection staphylococcal1
Xerosis1





Filtered ChEMBL targets:

Target UniProtKB ID Activity in nm Target Name Target gene
P00797 0.4 Renin RENI_HUMAN



Toxicity information:

Toxicity type: N/A



External links:

ChEBML: CHEMBL1639
DrugBank: DB09026