Isoxsuprine
General information:
| Withdrawn ID: | DB08941 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | C04AA01 |
| Molecular Formula: | C18H23NO3 |
| Molweight: | 301.386 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | No |
|---|---|
| First approved: | 1997 |
Side-effects:
| Total reported cases (submitted by medical professionals) with Isoxsuprine as primary suspect: | 2 |
|---|
Reported final outcomes:
| Congenital anomaly: | 1 |
|---|
Reported side-effects:
| Side-effect | Case number |
|---|---|
| LIMB MALFORMATION | 2 |
| MATERNAL DRUGS AFFECTING FOETUS | 2 |
| GESTATIONAL DIABETES | 1 |
| NEONATAL DISORDER | 1 |
| PREGNANCY | 1 |
| VAGINAL HAEMORRHAGE | 1 |
Filtered ChEMBL targets:
| Target UniProtKB ID | Activity in nm | Target Name | Target gene |
|---|---|---|---|
| Q16665 | 50.1 | Hypoxia-inducible factor 1-alpha | HIF1A_HUMAN |
Toxicity information:
| Toxicity class: | 3 |
|---|---|
| LD50: | 200 mg/kg |
External links:
| ChEBML: | CHEMBL1197051 |
|---|---|
| DrugBank: | DB08941 |