| APPLICATION SITE ERYTHEMA | 172 |
| APPLICATION SITE VESICLES | 154 |
| APPLICATION SITE PAIN | 130 |
| Incorrect drug administration duration | 124 |
| Drug administered at inappropriate site | 75 |
| APPLICATION SITE SCAB | 58 |
| APPLICATION SITE SWELLING | 52 |
| Drug ineffective | 48 |
| Inappropriate schedule of drug administration | 47 |
| Application site exfoliation | 46 |
| Incorrect dose administered | 44 |
| Squamous cell carcinoma | 42 |
| Squamous cell carcinoma of skin | 41 |
| Drug administration error | 39 |
| Application site reaction | 37 |
| Eye swelling | 36 |
| Accidental exposure to product | 30 |
| Application site burn | 29 |
| Application site pustules | 27 |
| Application site discharge | 27 |
| Headache | 26 |
| Eye irritation | 20 |
| Erythema | 20 |
| Application site inflammation | 20 |
| Hypersensitivity | 19 |
| Incorrect product administration duration | 18 |
| Application site erosion | 18 |
| Application site scar | 17 |
| Application site discolouration | 17 |
| Periorbital oedema | 16 |
| Application site ulcer | 16 |
| APPLICATION SITE PRURITUS | 16 |
| Product use issue | 15 |
| Eye pain | 15 |
| Skin reaction | 14 |
| Eyelid oedema | 14 |
| Application site oedema | 14 |
| Pain | 13 |
| Nausea | 13 |
| Medication error | 13 |
| Swelling face | 12 |
| Application site paraesthesia | 12 |
| Application site irritation | 12 |
| Inappropriate schedule of product administration | 11 |
| Herpes zoster | 11 |
| Product storage error | 10 |
| Dyspnoea | 10 |
| Drug dispensing error | 10 |
| DERMATITIS CONTACT | 10 |
| Blister | 10 |
| Pyrexia | 9 |
| Ocular hyperaemia | 9 |
| Basal cell carcinoma | 9 |
| Application site warmth | 9 |
| Application site infection | 9 |
| Application site dryness | 9 |
| Off label use | 8 |
| No adverse event | 8 |
| Lip swelling | 8 |
| Insomnia | 8 |
| Swollen tongue | 7 |
| Product packaging quantity issue | 7 |
| Influenza like illness | 7 |
| Incorrect product storage | 7 |
| Dizziness | 7 |
| Burns second degree | 7 |
| Adverse event | 7 |
| Treatment noncompliance | 6 |
| Social problem | 6 |
| Skin exfoliation | 6 |
| Pruritus | 6 |
| Paraesthesia oral | 6 |
| Neoplasm malignant | 6 |
| Inflammation | 6 |
| Diarrhoea | 6 |
| Application site rash | 6 |
| Application site haemorrhage | 6 |
| Angioedema | 6 |
| Visual impairment | 5 |
| Vision blurred | 5 |
| SKIN ULCER | 5 |
| Product use in unapproved indication | 5 |
| Paraesthesia | 5 |
| Lacrimation increased | 5 |
| Keratoacanthoma | 5 |
| Face oedema | 5 |
| Disease progression | 5 |
| Dermatitis | 5 |
| APPLICATION SITE HYPERSENSITIVITY | 5 |
| Vomiting | 4 |
| Skin lesion | 4 |
| Product quality issue | 4 |
| Oropharyngeal pain | 4 |
| Mouth ulceration | 4 |
| Malignant melanoma | 4 |
| Malaise | 4 |
| Fatigue | 4 |
| Dysphagia | 4 |
| Dermatitis bullous | 4 |
| Application site discomfort | 4 |
| Actinic keratosis | 4 |
| Wrong technique in product usage process | 3 |
| Wrong technique in drug usage process | 3 |
| Urticaria | 3 |
| Throat irritation | 3 |
| Therapeutic response unexpected | 3 |
| Swelling | 3 |
| Skin erosion | 3 |
| Sepsis | 3 |
| Scab | 3 |
| Rhinorrhoea | 3 |
| Quality of life decreased | 3 |
| Post inflammatory pigmentation change | 3 |
| Periorbital swelling | 3 |
| MYALGIA | 3 |
| Multiple use of single-use product | 3 |
| Lip oedema | 3 |
| Hypoaesthesia oral | 3 |
| Eye burns | 3 |
| Dysgeusia | 3 |
| Dry mouth | 3 |
| Disease recurrence | 3 |
| Corneal abrasion | 3 |
| Chills | 3 |
| Bowen's disease | 3 |
| Atypical fibroxanthoma | 3 |
| Asthenia | 3 |
| Application site papules | 3 |
| Application site induration | 3 |
| Accidental overdose | 3 |
| Visual acuity reduced | 2 |
| Trigeminal nerve disorder | 2 |
| Transient ischaemic attack | 2 |
| Toxicity to various agents | 2 |
| Toxic skin eruption | 2 |
| Throat tightness | 2 |
| Superinfection | 2 |
| STAPHYLOCOCCAL INFECTION | 2 |
| Skin warm | 2 |
| Sinus pain | 2 |
| Seborrhoeic keratosis | 2 |
| Scar | 2 |
| Rash pustular | 2 |
| Rash generalised | 2 |
| Rash erythematous | 2 |
| Rash | 2 |
| Pulmonary embolism | 2 |
| Product administration error | 2 |
| Product administered at inappropriate site | 2 |
| Pharyngeal oedema | 2 |
| Papule | 2 |
| Overdose | 2 |
| Oedema | 2 |
| Madarosis | 2 |
| Loss of consciousness | 2 |
| Local swelling | 2 |
| Lentigo maligna | 2 |
| Impetigo | 2 |
| Hypoaesthesia | 2 |
| Hypertension | 2 |
| Hyperkeratosis | 2 |
| Hyperhidrosis | 2 |
| Gait disturbance | 2 |
| Eyelid ptosis | 2 |
| Eye oedema | 2 |
| Exfoliative rash | 2 |
| Erysipelas | 2 |
| Diplopia | 2 |
| Dermatitis allergic | 2 |
| Condition aggravated | 2 |
| Cellulitis | 2 |
| Burns first degree | 2 |
| Blood pressure increased | 2 |
| Blindness transient | 2 |
| Blindness | 2 |
| Arthralgia | 2 |
| Application site telangiectasia | 2 |
| Anxiety | 2 |
| Anosmia | 2 |
| Anaphylactic reaction | 2 |
| Alopecia | 2 |
| Vitreous floaters | 1 |
| Vitreous detachment | 1 |
| VIIth nerve paralysis | 1 |
| Urinary retention | 1 |
| Unevaluable event | 1 |
| Underdose | 1 |
| Ulcerative keratitis | 1 |
| Ulcer | 1 |
| Tremor | 1 |
| Tooth disorder | 1 |
| Tongue pruritus | 1 |
| Tongue oedema | 1 |
| Tongue discomfort | 1 |
| Tongue discolouration | 1 |
| Thermal burn | 1 |
| Superinfection bacterial | 1 |
| Sudden death | 1 |
| Stevens-Johnson syndrome | 1 |
| Spontaneous haematoma | 1 |
| Somnolence | 1 |
| Skin tightness | 1 |
| Skin swelling | 1 |
| Skin squamous cell carcinoma recurrent | 1 |
| Skin neoplasm excision | 1 |
| Skin necrosis | 1 |
| Skin mass | 1 |
| Skin infection | 1 |
| Skin hypopigmentation | 1 |
| Skin hypertrophy | 1 |
| Skin fragility | 1 |
| Skin cancer metastatic | 1 |
| Skin cancer | 1 |
| Skin burning sensation | 1 |
| Sinusitis | 1 |
| Sinus disorder | 1 |
| Sensory disturbance | 1 |
| Sensation of foreign body | 1 |
| Secretion discharge | 1 |
| Scleritis | 1 |
| Sarcoma of skin | 1 |
| Rash morbilliform | 1 |
| Rash maculo-papular | 1 |
| Rash macular | 1 |
| Purulence | 1 |
| Pupils unequal | 1 |
| Pupillary disorder | 1 |
| Product container seal issue | 1 |
| Product container issue | 1 |
| Primary mediastinal large B-cell lymphoma | 1 |
| Prescribed overdose | 1 |
| Post herpetic neuralgia | 1 |
| Porokeratosis | 1 |
| Pneumonia aspiration | 1 |
| Pigmentation disorder | 1 |
| Photosensitivity reaction | 1 |
| Photophobia | 1 |
| Pharyngitis | 1 |
| Pharyngeal swelling | 1 |
| Pharyngeal erythema | 1 |
| Periorbital inflammation | 1 |
| Periorbital infection | 1 |
| Penile necrosis | 1 |
| Palpitations | 1 |
| Pain of skin | 1 |
| Pain in jaw | 1 |
| Otorrhoea | 1 |
| Osteoarthritis | 1 |
| Orthopnoea | 1 |
| Oral pain | 1 |
| Oral fungal infection | 1 |
| Ophthalmoplegia | 1 |
| Ophthalmic herpes zoster | 1 |
| Oedema peripheral | 1 |
| Ocular discomfort | 1 |
| Nonspecific reaction | 1 |
| Non-Hodgkin's lymphoma | 1 |
| No therapeutic response | 1 |
| Nipple pain | 1 |
| Neoplasm skin | 1 |
| Neoplasm progression | 1 |
| Myocardial infarction | 1 |
| Muscular weakness | 1 |
| Muscle contracture | 1 |
| Mucosal inflammation | 1 |
| Mouth haemorrhage | 1 |
| Migraine | 1 |
| Metastatic malignant melanoma | 1 |
| Metastases to lung | 1 |
| Melanocytic hyperplasia | 1 |
| Melaena | 1 |
| Macular fibrosis | 1 |
| Lymphoedema | 1 |
| Lymphadenopathy | 1 |
| Loss of personal independence in daily activities | 1 |
| Localised oedema | 1 |
| Liver function test abnormal | 1 |
| Lip pain | 1 |
| Lip blister | 1 |
| Lethargy | 1 |
| Laryngeal oedema | 1 |
| Lacrimation decreased | 1 |
| Keratosis pilaris | 1 |
| Keloid scar | 1 |
| Joint range of motion decreased | 1 |
| Joint instability | 1 |
| Intestinal obstruction | 1 |
| Initial insomnia | 1 |
| Influenza | 1 |
| Incorrect dosage administered | 1 |
| Impaired work ability | 1 |
| Impaired healing | 1 |
| IIIrd nerve paralysis | 1 |
| Hypokinesia | 1 |
| Hyperaesthesia | 1 |
| Hordeolum | 1 |
| Herpes zoster cutaneous disseminated | 1 |
| Herpes simplex | 1 |
| Heart rate increased | 1 |
| Haematemesis | 1 |
| Granuloma skin | 1 |
| Generalised erythema | 1 |
| Gastroenteritis | 1 |
| Fibrous histiocytoma | 1 |
| Feeling hot | 1 |
| Feeling abnormal | 1 |
| Fat necrosis | 1 |
| Fall | 1 |
| Facial paralysis | 1 |
| Facial pain | 1 |
| Facial asymmetry | 1 |
| Eyelid margin crusting | 1 |
| Eyelid irritation | 1 |
| Eye operation | 1 |
| Eye injury | 1 |
| Eye inflammation | 1 |
| Eye infection | 1 |
| Eye discharge | 1 |
| Erythema of eyelid | 1 |
| Eosinophilic cellulitis | 1 |
| Entropion | 1 |
| Eczema herpeticum | 1 |
| Eczema | 1 |
| Eating disorder | 1 |
| Ear pain | 1 |
| Dysuria | 1 |
| Dysphonia | 1 |
| Dry skin | 1 |
| Drug prescribing error | 1 |
| Drug intolerance | 1 |
| Drug hypersensitivity | 1 |
| Drug dose omission | 1 |
| Dermatitis exfoliative | 1 |
| Dermatitis atopic | 1 |
| Dental necrosis | 1 |
| Dental discomfort | 1 |
| Deafness | 1 |
| Cough | 1 |
| Corneal infection | 1 |
| Corneal graft rejection | 1 |
| Corneal bleeding | 1 |
| Conjunctivitis | 1 |
| Conjunctival hyperaemia | 1 |
| Concomitant disease progression | 1 |
| Cold sweat | 1 |
| Circumoral oedema | 1 |
| Chest pain | 1 |
| Chest discomfort | 1 |
| Chemical eye injury | 1 |
| Carcinoma in situ | 1 |
| Cancer surgery | 1 |
| Burns third degree | 1 |
| Burning sensation | 1 |
| Breath odour | 1 |
| Breast cancer | 1 |
| Bradycardia | 1 |
| Bone pain | 1 |
| Body temperature increased | 1 |
| Blister rupture | 1 |
| Blindness unilateral | 1 |
| Basosquamous carcinoma | 1 |
| Bacterial infection | 1 |
| Atrial fibrillation | 1 |
| Application site wound | 1 |
| Application site urticaria | 1 |
| Application site nodule | 1 |
| Application site hypoaesthesia | 1 |
| Application site fissure | 1 |
| Application site extravasation | 1 |
| Application site dermatitis | 1 |
| Application site bruise | 1 |
| Aphthous stomatitis | 1 |
| Anaphylactoid reaction | 1 |
| Anaphylactic shock | 1 |
| Alopecia scarring | 1 |
| Allergic keratitis | 1 |
| Aggression | 1 |
| Ageusia | 1 |
| Administration site scar | 1 |
| Administration site indentation | 1 |
| Activities of daily living impaired | 1 |
| Acne | 1 |
| Abscess bacterial | 1 |
| Abdominal pain | 1 |
| Abdominal discomfort | 1 |
