Result page for
Withdrawn ID DB00382:
Tacrine
![DB00382](./images/DB00382.png)
General information:
Withdrawal information:
Withdrawn due to drug safety reasons: | No |
First approved: |
1993 |
First withdrawn: |
2013 |
Last withdrawn: |
2013 |
Filtered ChEMBL targets:
Target UniProtKB ID |
Activity in nm |
Target Name |
Target gene |
P05067 |
12.21 |
Amyloid-beta precursor protein |
A4_HUMAN |
P06276 |
7 |
Cholinesterase |
CHLE_HUMAN |
P22303 |
7.53 |
Acetylcholinesterase |
ACES_HUMAN |
Q04844 |
152.28 |
Acetylcholine receptor subunit epsilon |
ACHE_HUMAN |
Toxicity information:
Toxicity class: |
3 |
Toxicity type: |
N/A |
LD50: |
290 mg/kg |
External links: