Tacrine

General information:

Withdrawn ID:	DB00382
Canonical SMILES:
Standard InChI:
Standard InChIKey:
ATC class(es):	N06DA01
Molecular Formula:	C13H14N2
Molweight:	198.264

Withdrawal information:

Withdrawn due to drug safety reasons:	No
First approved:	1993
First withdrawn:	2013
Last withdrawn:	2013

Filtered ChEMBL targets:

Target UniProtKB ID	Activity in nm	Target Name	Target gene
P05067	12.21	Amyloid-beta precursor protein	A4_HUMAN
P06276	7	Cholinesterase	CHLE_HUMAN
P22303	7.53	Acetylcholinesterase	ACES_HUMAN
Q04844	152.28	Acetylcholine receptor subunit epsilon	ACHE_HUMAN

Toxicity information:

Toxicity class:	3
Toxicity type:	N/A
LD50:	290 mg/kg

External links:

ChEBML:	CHEMBL95
DrugBank:	DB00382